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The map label for this gene is CYP107B1 [H]

Identifier: 170750277

GI number: 170750277

Start: 4128503

End: 4129744

Strand: Direct

Name: CYP107B1 [H]

Synonym: Mrad2831_3880

Alternate gene names: 170750277

Gene position: 4128503-4129744 (Clockwise)

Preceding gene: 170750276

Following gene: 170750278

Centisome position: 67.93

GC content: 73.11

Gene sequence:

>1242_bases
ATGTCTGACGACGCGCTGTTCGCCGCCGTGATGGATCCGGCCAACCGGGCCGACCCGTACCCGCTCTATCGACGGATGCG
GCAGCAGCCGGTCTCGCGCCAGCGCGACGGCAGCTACGTCGTCTCCACGCACGCGGCGATCCGCAGCCTGCTGTTCGACC
CGCGGCTCAGCTCCGAGGACCTGCCGCCGCCCCGGCGGCCCCGCACCGGCAACCCGCTCAAGGACCTGATCCTCAACCCG
ATCAAGAACCGCATCAGCGCCACGCACCGTCCGTTCATCTTCCGCGACCCCCCGGACCACGACCGGCTGCGCAGCCTGGT
GATGCGGGAATTCTCGATCGCGCGGGTGCAGGCGCTGCGGCCGCGGATCGCCCGGGAGGTGGACGGCCTGATCGACGCGT
GCCGGGAGCGGCGGGAGGTCTGCCTCGTGAGCGACCTGTCCTACCCCCTGCCGGTGACGGTGATCTGCGAGCTGCTCGGC
GTGCCGCGCGCGGACGAGCCGCGGTTCCAGGCCTGGGCGACGCAGCTCGCCACCGCCGTGGAGCCGGACGCGCGCCACGA
CGACGGGACCCGGCGCCAGATCGTCGGCGCCTTCGACGAGATCGCCGCCTACATGCGCGACCTCATCCGCGAGAAGCGCC
GCCGCCCGGCGGACGACATGCTGAGCGGCCTCGCCGCCCCCGGCCCGGACGGCCGGAAGCAGATGAGCGACTTCGACCTG
CTGTCGACGGCGGTCCTGCTGCTGGTCGCGGGTCACGAGACCACCGTGAACCTCATCACCAACGCGATGCTGACCCTGCT
CCGGCATCCCGAGGAGCTGGAGCGGCTCAAGGCCGATCCCGAGCGGGCCCCGCGGCTGATCGAGGAGGTCCTGCGCTACG
AGCCGCCGGTGCATTTCCGGACCCGCAAGGCCCTCGGCGCGATCGCGGTGGCCGGCGAGATGATCCCCAAGGGCGCGCCC
GTCATCCTGATGTTCGCGGCCGCGAACCGCGATCCCGACCGGTTCGCGGCGCCCGACCGCTTCGATCCCGACCGGGGCGA
CATCGAGCATTTCGGCTTCGGCGGGGGCCTGCACTACTGCGTCGGCGCACCCCTGGCGCGGCTCGAGGCCGAGATCGCCC
TGGTTGCGCTCAGCCGCCGCCTCGTCGCCCCGCGGCTCGCGGTCGATCCGCCGCCCTACCGGCCGGGCGCGTCGCTCCGG
GGGCCCGAGCAGCTGCGGATCGGCATCGACGGCGTCGCCTGA

Upstream 100 bases:

>100_bases
ATCACCGACGCCACCGACCGGCCGCGCGTCGAGATGGCGGTCCCGGGCTTCCCGCCGCCGCACCGAGCCGCCGAGGCGCG
GCCTTCCGCCGAGACCGTCC

Downstream 100 bases:

>100_bases
CCCTGGCCGTGCCCGCGCGACTCGTGAAGCGGCGGTAAACGGGTCTGTTTCACGTGAAACATTCGTAAACCCCTTCGCCC
CGAGGCGGGGCGCGCCGCCG

Product: cytochrome P450

Products: NA

Alternate protein names: Cytochrome P450CVIIB1 [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSDDALFAAVMDPANRADPYPLYRRMRQQPVSRQRDGSYVVSTHAAIRSLLFDPRLSSEDLPPPRRPRTGNPLKDLILNP
IKNRISATHRPFIFRDPPDHDRLRSLVMREFSIARVQALRPRIAREVDGLIDACRERREVCLVSDLSYPLPVTVICELLG
VPRADEPRFQAWATQLATAVEPDARHDDGTRRQIVGAFDEIAAYMRDLIREKRRRPADDMLSGLAAPGPDGRKQMSDFDL
LSTAVLLLVAGHETTVNLITNAMLTLLRHPEELERLKADPERAPRLIEEVLRYEPPVHFRTRKALGAIAVAGEMIPKGAP
VILMFAAANRDPDRFAAPDRFDPDRGDIEHFGFGGGLHYCVGAPLARLEAEIALVALSRRLVAPRLAVDPPPYRPGASLR
GPEQLRIGIDGVA

Sequences:

>Translated_413_residues
MSDDALFAAVMDPANRADPYPLYRRMRQQPVSRQRDGSYVVSTHAAIRSLLFDPRLSSEDLPPPRRPRTGNPLKDLILNP
IKNRISATHRPFIFRDPPDHDRLRSLVMREFSIARVQALRPRIAREVDGLIDACRERREVCLVSDLSYPLPVTVICELLG
VPRADEPRFQAWATQLATAVEPDARHDDGTRRQIVGAFDEIAAYMRDLIREKRRRPADDMLSGLAAPGPDGRKQMSDFDL
LSTAVLLLVAGHETTVNLITNAMLTLLRHPEELERLKADPERAPRLIEEVLRYEPPVHFRTRKALGAIAVAGEMIPKGAP
VILMFAAANRDPDRFAAPDRFDPDRGDIEHFGFGGGLHYCVGAPLARLEAEIALVALSRRLVAPRLAVDPPPYRPGASLR
GPEQLRIGIDGVA
>Mature_412_residues
SDDALFAAVMDPANRADPYPLYRRMRQQPVSRQRDGSYVVSTHAAIRSLLFDPRLSSEDLPPPRRPRTGNPLKDLILNPI
KNRISATHRPFIFRDPPDHDRLRSLVMREFSIARVQALRPRIAREVDGLIDACRERREVCLVSDLSYPLPVTVICELLGV
PRADEPRFQAWATQLATAVEPDARHDDGTRRQIVGAFDEIAAYMRDLIREKRRRPADDMLSGLAAPGPDGRKQMSDFDLL
STAVLLLVAGHETTVNLITNAMLTLLRHPEELERLKADPERAPRLIEEVLRYEPPVHFRTRKALGAIAVAGEMIPKGAPV
ILMFAAANRDPDRFAAPDRFDPDRGDIEHFGFGGGLHYCVGAPLARLEAEIALVALSRRLVAPRLAVDPPPYRPGASLRG
PEQLRIGIDGVA

Specific function: Not known, probably involved in the catabolism of octane and guaiacol. It displays a weak activity in the O-dealkylation of 7-ethoxycoumarin [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Homo sapiens, GI310125130, Length=210, Percent_Identity=31.4285714285714, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI190570174, Length=210, Percent_Identity=31.4285714285714, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI310125128, Length=210, Percent_Identity=31.4285714285714, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI14550409, Length=210, Percent_Identity=31.4285714285714, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI13435386, Length=247, Percent_Identity=21.0526315789474, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI4503211, Length=232, Percent_Identity=28.0172413793103, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI4503231, Length=341, Percent_Identity=20.2346041055718, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI16933533, Length=197, Percent_Identity=23.3502538071066, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI115532670, Length=197, Percent_Identity=26.9035532994924, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71982977, Length=197, Percent_Identity=26.3959390862944, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71982956, Length=198, Percent_Identity=26.2626262626263, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24642101, Length=193, Percent_Identity=31.6062176165803, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21355669, Length=220, Percent_Identity=26.3636363636364, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 46102; Mature: 45970

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDALFAAVMDPANRADPYPLYRRMRQQPVSRQRDGSYVVSTHAAIRSLLFDPRLSSED
CCCCCEEHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCC
LPPPRRPRTGNPLKDLILNPIKNRISATHRPFIFRDPPDHDRLRSLVMREFSIARVQALR
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHH
PRIAREVDGLIDACRERREVCLVSDLSYPLPVTVICELLGVPRADEPRFQAWATQLATAV
HHHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
EPDARHDDGTRRQIVGAFDEIAAYMRDLIREKRRRPADDMLSGLAAPGPDGRKQMSDFDL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHH
LSTAVLLLVAGHETTVNLITNAMLTLLRHPEELERLKADPERAPRLIEEVLRYEPPVHFR
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHH
TRKALGAIAVAGEMIPKGAPVILMFAAANRDPDRFAAPDRFDPDRGDIEHFGFGGGLHYC
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHCCCCCCCCCCCCCCCCCCCCCCHHHH
VGAPLARLEAEIALVALSRRLVAPRLAVDPPPYRPGASLRGPEQLRIGIDGVA
HCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCC
>Mature Secondary Structure 
SDDALFAAVMDPANRADPYPLYRRMRQQPVSRQRDGSYVVSTHAAIRSLLFDPRLSSED
CCCCEEHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCC
LPPPRRPRTGNPLKDLILNPIKNRISATHRPFIFRDPPDHDRLRSLVMREFSIARVQALR
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHH
PRIAREVDGLIDACRERREVCLVSDLSYPLPVTVICELLGVPRADEPRFQAWATQLATAV
HHHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
EPDARHDDGTRRQIVGAFDEIAAYMRDLIREKRRRPADDMLSGLAAPGPDGRKQMSDFDL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHH
LSTAVLLLVAGHETTVNLITNAMLTLLRHPEELERLKADPERAPRLIEEVLRYEPPVHFR
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHH
TRKALGAIAVAGEMIPKGAPVILMFAAANRDPDRFAAPDRFDPDRGDIEHFGFGGGLHYC
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHCCCCCCCCCCCCCCCCCCCCCCHHHH
VGAPLARLEAEIALVALSRRLVAPRLAVDPPPYRPGASLRGPEQLRIGIDGVA
HCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732208 [H]