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The map label for this gene is alsR [H]

Identifier: 170750269

GI number: 170750269

Start: 4121724

End: 4122644

Strand: Reverse

Name: alsR [H]

Synonym: Mrad2831_3872

Alternate gene names: 170750269

Gene position: 4122644-4121724 (Counterclockwise)

Preceding gene: 170750270

Following gene: 170750268

Centisome position: 67.83

GC content: 76.11

Gene sequence:

>921_bases
ATGTCCGCCGACCTGCCCGCGGCCGCGACCCTGAGCCGCCTCGACCTGAAGACGCTCCGGCTGTTCGCGGCCATCTGCGC
GGAGGGGACGCTGAACGGCGCGGCCCGCCGCGCGGCGATCGCGCCCTCGGCGGTCAGCAAGCGCCTCGCCGAACTGGAGC
ACGCGCTGGGCTGCACCTTGCTCACCCGCGAGCCGCGCGGCATGCGGCTCACGCCGGCCGGCGAGACCCTGCTGCACCAC
ACGCGCCGGATGCTGGCGAGCGCCGAGCAGATCGCCCTGGAACTCGCCGAGCACGCCCGGGGCGTGCGCGGCTTCGTGCG
GGTGCTCGCCAACCTCTCGGCCATCGTGGAGTTCCTGCCCGAGGACCTGCAGGCCTTCCTGGCCGCGCAGGACGGGATCC
GGGTCGACCTCGAGGAGCGCCCGAGCGGCGGCGTCGTCGCCGGCGTCGAGGAGGGGTTCGCCGATCTCGGCCTCTGCGCC
GACAACACCGACACCCGCGGCCTCACCGCCTACCCGTACCGGAGCGACCGCCTCGTCCTGGTGATGCCGGCCGGGCATCC
CCTGAGCGGCCGCGGCGCCGTCGCGCTGGCCGACAGCCTCGACTACGACCATGTCGGGCTGCACGCGGAGAGCTCGATCT
ACGCCGCCCTGCGCGACGAGGCCCGGCGCCTCGGCCGGCCGCTGCGGCTGCGGATGCACGTGCCGAGCTTCGACGCGATC
TGCCGCATGGCGCAGGTCGGCCTGGGGCTCGGCACCGTGCCGGAGCGCGTCTACGCCCTGCTCGGGCCGCCGATGCGCCT
CACGGCGGTGCCGCTCACCGATCCCTGGGCCGCGCGCACGCTGCGCCTCGTGGTCCGCCCGGGCGCCCTGCCGCCCGCGG
CCGCCCTCCTGCTGGAGCATCTCCGGGCCGCCGGTCGCTGA

Upstream 100 bases:

>100_bases
TTCGGCCTCGTCAACCGCGAGGGGGCCAAGGCCGGCCTCGGCACCTACGGCCAGCCGGTCGGCTCCCGCGACTGACGGCC
CGCCCGCACCGCGCCGCCGG

Downstream 100 bases:

>100_bases
GCGTGCGTTCTCCGGCGGCGAACGCACGGTGGTGCATGGCGTTTGGACTTGGCCACCGGAAGGGCCCTATCTCCGGGGCA
ACAAACGATGGAGGAAAGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSADLPAAATLSRLDLKTLRLFAAICAEGTLNGAARRAAIAPSAVSKRLAELEHALGCTLLTREPRGMRLTPAGETLLHH
TRRMLASAEQIALELAEHARGVRGFVRVLANLSAIVEFLPEDLQAFLAAQDGIRVDLEERPSGGVVAGVEEGFADLGLCA
DNTDTRGLTAYPYRSDRLVLVMPAGHPLSGRGAVALADSLDYDHVGLHAESSIYAALRDEARRLGRPLRLRMHVPSFDAI
CRMAQVGLGLGTVPERVYALLGPPMRLTAVPLTDPWAARTLRLVVRPGALPPAAALLLEHLRAAGR

Sequences:

>Translated_306_residues
MSADLPAAATLSRLDLKTLRLFAAICAEGTLNGAARRAAIAPSAVSKRLAELEHALGCTLLTREPRGMRLTPAGETLLHH
TRRMLASAEQIALELAEHARGVRGFVRVLANLSAIVEFLPEDLQAFLAAQDGIRVDLEERPSGGVVAGVEEGFADLGLCA
DNTDTRGLTAYPYRSDRLVLVMPAGHPLSGRGAVALADSLDYDHVGLHAESSIYAALRDEARRLGRPLRLRMHVPSFDAI
CRMAQVGLGLGTVPERVYALLGPPMRLTAVPLTDPWAARTLRLVVRPGALPPAAALLLEHLRAAGR
>Mature_305_residues
SADLPAAATLSRLDLKTLRLFAAICAEGTLNGAARRAAIAPSAVSKRLAELEHALGCTLLTREPRGMRLTPAGETLLHHT
RRMLASAEQIALELAEHARGVRGFVRVLANLSAIVEFLPEDLQAFLAAQDGIRVDLEERPSGGVVAGVEEGFADLGLCAD
NTDTRGLTAYPYRSDRLVLVMPAGHPLSGRGAVALADSLDYDHVGLHAESSIYAALRDEARRLGRPLRLRMHVPSFDAIC
RMAQVGLGLGTVPERVYALLGPPMRLTAVPLTDPWAARTLRLVVRPGALPPAAALLLEHLRAAGR

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=285, Percent_Identity=23.859649122807, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787806, Length=289, Percent_Identity=24.9134948096886, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI2367136, Length=254, Percent_Identity=25.5905511811024, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32691; Mature: 32560

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADLPAAATLSRLDLKTLRLFAAICAEGTLNGAARRAAIAPSAVSKRLAELEHALGCTL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCEE
LTREPRGMRLTPAGETLLHHTRRMLASAEQIALELAEHARGVRGFVRVLANLSAIVEFLP
EECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDLQAFLAAQDGIRVDLEERPSGGVVAGVEEGFADLGLCADNTDTRGLTAYPYRSDRLVL
HHHHHHHHHCCCCEEECCCCCCCCEEECHHHCHHHHCCCCCCCCCCCEEECCCCCCCEEE
VMPAGHPLSGRGAVALADSLDYDHVGLHAESSIYAALRDEARRLGRPLRLRMHVPSFDAI
EEECCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHH
CRMAQVGLGLGTVPERVYALLGPPMRLTAVPLTDPWAARTLRLVVRPGALPPAAALLLEH
HHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHEEEEECCCCCCHHHHHHHHH
LRAAGR
HHHCCC
>Mature Secondary Structure 
SADLPAAATLSRLDLKTLRLFAAICAEGTLNGAARRAAIAPSAVSKRLAELEHALGCTL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCEE
LTREPRGMRLTPAGETLLHHTRRMLASAEQIALELAEHARGVRGFVRVLANLSAIVEFLP
EECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDLQAFLAAQDGIRVDLEERPSGGVVAGVEEGFADLGLCADNTDTRGLTAYPYRSDRLVL
HHHHHHHHHCCCCEEECCCCCCCCEEECHHHCHHHHCCCCCCCCCCCEEECCCCCCCEEE
VMPAGHPLSGRGAVALADSLDYDHVGLHAESSIYAALRDEARRLGRPLRLRMHVPSFDAI
EEECCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHH
CRMAQVGLGLGTVPERVYALLGPPMRLTAVPLTDPWAARTLRLVVRPGALPPAAALLLEH
HHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHEEEEECCCCCCHHHHHHHHH
LRAAGR
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]