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The map label for this gene is ttuB [H]

Identifier: 170750266

GI number: 170750266

Start: 4117839

End: 4119167

Strand: Reverse

Name: ttuB [H]

Synonym: Mrad2831_3869

Alternate gene names: 170750266

Gene position: 4119167-4117839 (Counterclockwise)

Preceding gene: 170750267

Following gene: 170750265

Centisome position: 67.77

GC content: 69.07

Gene sequence:

>1329_bases
ATGACCGCAGCCCTGTCCGGGTCGCCGGCCGCCGCCGAGACCGGCGCGGTGACGGAGACCGGCGTCGTCCGCAAGGTCGC
GTGGCGGCTCATGCCGCTGATCATGATCTGCTACATGTTCGCGTTCTTCGACCGCATCAACATCAGCTTCGCCAAGTTCC
AGCTCCAGAGCGACCTCGGCTTCAGCAACGTCGCCTACGGACTCGGCGCGAGCATGTTCGTGGTCGGCTACGTGATCTTC
GAGGTGCCCTCGAACCTGTTCCTCTACCGGGTCGGGGCGCGGCGCTGGATCGCCCGGATCATGATCTCCTGGGGCATCGC
CACCGCGCTGATGATCTTCATCCGCAGCGAGTGGCACTTCTACGCCCTGCGCTTCCTGATCGGCGCGATGGAGGCGGGCT
TCGCCCCCGGCATCCTCTACTACCTGACCATCTGGTTCCCGGCCTCGCATCGCGGCCGCATCACCTCGTTCATGTTCGTG
GCCTCGGCCTTCTCGGGGATCTTCGGCGCGCCGGTGGCGGGCCTGATCCTCGGCGGCCTCAACGGCGTCGGGGGCCTCGC
CGGCTGGCAATGGCTGTTCCTGGCCGGCGGCCTGCCCTGCCTCGTGCTCGGAATGCTCGTGCTGACGCGCCTCGACGACC
GGATCGCCGACGCCCGCTGGCTGTCCGAGCCCGAGAAGGCGCTCCTGTCGAGCCGGATCGCCCACCACAACCGGGATATC
GGCGACCACTCGCTGATCGGGGCGATCAAGCAGCCGGGCTTCCTGCTGATCGCGCTGATCTACTTCCTGCTCCAGATCGG
CTCCTACGGGCTGAACTTCTGGGGGCCGGACCTGATCAAGACCGCGAGCGGCGGGCAGGCGGCCTCGGTGGGTTTCCTGA
CGGCGATTCCCTACATCTGCGGGGCGATCAGCATGGTGGTGATCGGACGCCTGTCCGACGCCTCGGGCGAGCGGCCGAAA
TTCGTCGCCGGCCTCGCCATCGCGGCGGCGCTCGGCTTCTTCGGCGCCGGCCTGTTCGACAAGCACATCGTGCCGCTGAT
GTTCGCCCTGGCGCTGCTGGGGGCCGGCATCGTCGCGTCGATCCCGACCTTCTGGACGCTGCCGGCCAAGCTCGTCACCG
GCGTCGGCGCGGCCGGCGGGATCGCGCTGATCAACACGCTCGGGCAGTTCGGCGGCATCGTCAGCCCGGTGATGGTCGGC
TGGGTGAAGGATCTCACCGGCTCGACGACGCCCGCGCTCTACGGGATCGGCGTGCTCTGCCTCGTCGCCGCCGGGCTGGC
GCTCTTCGCCATGCCGGCGAGCCTGCGCCGGAGCGACCGCGCGGCGTGA

Upstream 100 bases:

>100_bases
TGCCGTGAGCTGCGCCCGAACCTGACTTCGCGGAAAGCCGCCCGTCCGAAGGCGGCACCGCCCAAGACACGTCCCTCAAG
AACACACCACGGAGGAAACC

Downstream 100 bases:

>100_bases
GACGGCCCGCCGCCCGGCGTGGCCGGGGTGGCGGATCTCGGGCGGCGGCGCGGGCCGCCAGCGGTCGTCGCGGGGCTTTA
GGCCGCGACGGACCTTGAAG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MTAALSGSPAAAETGAVTETGVVRKVAWRLMPLIMICYMFAFFDRINISFAKFQLQSDLGFSNVAYGLGASMFVVGYVIF
EVPSNLFLYRVGARRWIARIMISWGIATALMIFIRSEWHFYALRFLIGAMEAGFAPGILYYLTIWFPASHRGRITSFMFV
ASAFSGIFGAPVAGLILGGLNGVGGLAGWQWLFLAGGLPCLVLGMLVLTRLDDRIADARWLSEPEKALLSSRIAHHNRDI
GDHSLIGAIKQPGFLLIALIYFLLQIGSYGLNFWGPDLIKTASGGQAASVGFLTAIPYICGAISMVVIGRLSDASGERPK
FVAGLAIAAALGFFGAGLFDKHIVPLMFALALLGAGIVASIPTFWTLPAKLVTGVGAAGGIALINTLGQFGGIVSPVMVG
WVKDLTGSTTPALYGIGVLCLVAAGLALFAMPASLRRSDRAA

Sequences:

>Translated_442_residues
MTAALSGSPAAAETGAVTETGVVRKVAWRLMPLIMICYMFAFFDRINISFAKFQLQSDLGFSNVAYGLGASMFVVGYVIF
EVPSNLFLYRVGARRWIARIMISWGIATALMIFIRSEWHFYALRFLIGAMEAGFAPGILYYLTIWFPASHRGRITSFMFV
ASAFSGIFGAPVAGLILGGLNGVGGLAGWQWLFLAGGLPCLVLGMLVLTRLDDRIADARWLSEPEKALLSSRIAHHNRDI
GDHSLIGAIKQPGFLLIALIYFLLQIGSYGLNFWGPDLIKTASGGQAASVGFLTAIPYICGAISMVVIGRLSDASGERPK
FVAGLAIAAALGFFGAGLFDKHIVPLMFALALLGAGIVASIPTFWTLPAKLVTGVGAAGGIALINTLGQFGGIVSPVMVG
WVKDLTGSTTPALYGIGVLCLVAAGLALFAMPASLRRSDRAA
>Mature_441_residues
TAALSGSPAAAETGAVTETGVVRKVAWRLMPLIMICYMFAFFDRINISFAKFQLQSDLGFSNVAYGLGASMFVVGYVIFE
VPSNLFLYRVGARRWIARIMISWGIATALMIFIRSEWHFYALRFLIGAMEAGFAPGILYYLTIWFPASHRGRITSFMFVA
SAFSGIFGAPVAGLILGGLNGVGGLAGWQWLFLAGGLPCLVLGMLVLTRLDDRIADARWLSEPEKALLSSRIAHHNRDIG
DHSLIGAIKQPGFLLIALIYFLLQIGSYGLNFWGPDLIKTASGGQAASVGFLTAIPYICGAISMVVIGRLSDASGERPKF
VAGLAIAAALGFFGAGLFDKHIVPLMFALALLGAGIVASIPTFWTLPAKLVTGVGAAGGIALINTLGQFGGIVSPVMVGW
VKDLTGSTTPALYGIGVLCLVAAGLALFAMPASLRRSDRAA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=378, Percent_Identity=35.1851851851852, Blast_Score=224, Evalue=9e-60,
Organism=Escherichia coli, GI1789152, Length=440, Percent_Identity=26.5909090909091, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082320, Length=420, Percent_Identity=24.2857142857143, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI2367379, Length=467, Percent_Identity=24.4111349036403, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789515, Length=440, Percent_Identity=23.6363636363636, Blast_Score=65, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322025, Length=238, Percent_Identity=26.4705882352941, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321698, Length=323, Percent_Identity=23.8390092879257, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319876, Length=227, Percent_Identity=25.5506607929515, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319250, Length=172, Percent_Identity=25.5813953488372, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6322612, Length=281, Percent_Identity=23.4875444839858, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46859; Mature: 46728

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAALSGSPAAAETGAVTETGVVRKVAWRLMPLIMICYMFAFFDRINISFAKFQLQSDLG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEHHCCC
FSNVAYGLGASMFVVGYVIFEVPSNLFLYRVGARRWIARIMISWGIATALMIFIRSEWHF
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
YALRFLIGAMEAGFAPGILYYLTIWFPASHRGRITSFMFVASAFSGIFGAPVAGLILGGL
HHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHCC
NGVGGLAGWQWLFLAGGLPCLVLGMLVLTRLDDRIADARWLSEPEKALLSSRIAHHNRDI
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
GDHSLIGAIKQPGFLLIALIYFLLQIGSYGLNFWGPDLIKTASGGQAASVGFLTAIPYIC
CCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHH
GAISMVVIGRLSDASGERPKFVAGLAIAAALGFFGAGLFDKHIVPLMFALALLGAGIVAS
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHH
IPTFWTLPAKLVTGVGAAGGIALINTLGQFGGIVSPVMVGWVKDLTGSTTPALYGIGVLC
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LVAAGLALFAMPASLRRSDRAA
HHHHHHHHHHCCHHHHHCCCCC
>Mature Secondary Structure 
TAALSGSPAAAETGAVTETGVVRKVAWRLMPLIMICYMFAFFDRINISFAKFQLQSDLG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEHHCCC
FSNVAYGLGASMFVVGYVIFEVPSNLFLYRVGARRWIARIMISWGIATALMIFIRSEWHF
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
YALRFLIGAMEAGFAPGILYYLTIWFPASHRGRITSFMFVASAFSGIFGAPVAGLILGGL
HHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHCC
NGVGGLAGWQWLFLAGGLPCLVLGMLVLTRLDDRIADARWLSEPEKALLSSRIAHHNRDI
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
GDHSLIGAIKQPGFLLIALIYFLLQIGSYGLNFWGPDLIKTASGGQAASVGFLTAIPYIC
CCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHH
GAISMVVIGRLSDASGERPKFVAGLAIAAALGFFGAGLFDKHIVPLMFALALLGAGIVAS
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHH
IPTFWTLPAKLVTGVGAAGGIALINTLGQFGGIVSPVMVGWVKDLTGSTTPALYGIGVLC
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LVAAGLALFAMPASLRRSDRAA
HHHHHHHHHHCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]