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The map label for this gene is rpoC [H]

Identifier: 170750236

GI number: 170750236

Start: 4082987

End: 4087198

Strand: Reverse

Name: rpoC [H]

Synonym: Mrad2831_3838

Alternate gene names: 170750236

Gene position: 4087198-4082987 (Counterclockwise)

Preceding gene: 170750237

Following gene: 170750235

Centisome position: 67.25

GC content: 66.38

Gene sequence:

>4212_bases
ATGAACCAAGAGGTCATGAACCTTTTCAACCAGCAGGCCCAGCCGGTCAGCTTCGACCAGATCAAGATCTCGATCTCGTC
CCCGGAGAAGATCCTCTCCTGGTCGTACGGCGAGATCAAGAAGCCCGAGACCATCAACTACCGGACCTTCAAGCCCGAGC
GCGACGGCCTGTTCTGCGCGCGCATCTTCGGACCGATCAAGGACTACGAGTGCTTGTGCGGCAAGTACAAGCGCATGAAG
TACAAGGGCGTCATCTGCGAGAAGTGCGGCGTCGAGGTCACCCTCGCGCGCGTCCGGCGCGACCGCATGGGCCACATCGA
GCTGGCCGCCCCCGTCGCGCACATCTGGTTCCTGAAGTCGCTGCCGAGCCGCATCGGCCTGCTGCTCGACATGGCGCTCA
AGGACCTCGAGCGGATCCTGTACTTCGAGTCGTACTGCGTCATCGAGCCGGGCCTCACCCCCCTGAAGGAGCGTCAGCTC
CTGTCGGAGGAGGAGTACCTGCGCGCGCAGGAGGAGTACGGCGAGGATAGCTTCACGGCCATGATCGGCGCCGAGGCCAT
CCGGCGCATCCTGCAGGAGCTCGACCTCGACAAGATCGCCAACGACCTGCGCGAGGAGATCGCGGTCACCACCTCGGAGC
TGAAGCCCAAGAAGCTCCTGAAGCGGCTCAAGATCATCGAGGCATTCCAGATGTCCGGCAACAAGCCGGAATGGATGATC
CTGACGGTCGTGCCGGTGATCCCGCCGGACCTGCGCCCGCTGGTCCCGCTGGACGGCGGCCGCTTCGCGACCTCCGACCT
CAACGATCTGTACCGCCGCGTCATCAACCGCAACAACCGCCTGAAGCGGCTGATCGAGCTGCGCGCGCCCGACATCATCA
TCCGCAACGAGAAGCGGATGCTGCAGGAGGCGGTCGACGCGCTGTTCGACAACGGCCGCCGCGGCCGCGTCATCACGGGC
GCCAACAAGCGCCCGCTGAAGTCGCTCGCCGACATGCTGAAGGGCAAGCAGGGCCGGTTCCGCCAGAACCTGCTCGGCAA
GCGCGTCGACTACTCGGGCCGCTCGGTCATCGTGGTCGGTCCGGAGCTGAAGCTGCACCAGTGCGGCCTGCCCAAGAAGA
TGGCGCTGGAGCTGTTCAAGCCGTTCATCTACGCGCGCCTCGACGCCAAGGGTTTCTCGGCCACCGTCAAGCAGGCCAAG
AAGCTCGTGGAGAAGGAGAAGCCGGAGGTCTGGGACATCCTCGATGAGGTGATCCGCGAGCACCCGGTGATGCTGAACCG
CGCGCCGACGCTGCACCGCCTCGGCATCCAGGCCTTCGAGCCGAAGCTGATCGAGGGCAAGGCGATCCAGCTGCACCCGC
TGGTCTGCGCCGCGTTCAACGCCGACTTCGACGGCGACCAGATGGCCGTGCACGTCCCGCTGTCGCTCGAGGCGCAGCTG
GAAGCGCGCGTCCTGATGATGTCGACCAACAACATCCTGCACCCGGCCAACGGTCAGCCGATCATCGTGCCGTCGCAGGA
CATCGTGCTCGGCCTCTACTACCTGTCGATCGTGGCCGAGGGCGCGCCGGGCGAGTACAAGCCCGACAACGCCAAGAACC
CGATGCAGGGCGTCTACGGCGACATGGGCGAGCTCGAGCACGCCCTGGCCGCCAAGGCCGTGTCGCTGCACTCGAAGATC
AAGTGGCGCTGGACCGGCATCGGCCCGGACGGCGAGCCCCTGACCAAGACCTACGAGACCACCCCCGGCCGCGTGATCCT
CTCCGGCGCCCTGCCGAAGCACGCCAAGGTGCCCTTCGACGTCGTCAACAAGCTGATGACCAAGAAGGAGATCTCGGCGA
TGATCGACACCGTCTACCGCCACTGCGGTCAGAAGGAGTCGGTGATCTTCTGTGACCGGATCATGGCGCTCGGCTTCAAC
CACGCGTTCAAGGCCGGCATTTCGTTCGGCAAGGACGACATGGTCGTGCCGGAGAACAAGTGGTCGATCGTCGACACGAC
CCGCGCGCTCGTGAAGGATTACGAGCAGCAGTACAACGACGGCCTGATCACCCAGGGCGAGAAGTACAACAAGGTGGTCG
ACGCCTGGGCCAAGTGCTCGGACAAGCTGGCCGCCGAGATGATGGGCCGCATCTCCAGCGTCCAGAAGGACGAGAAGGGT
GCGGACAAGCAGGTCAACTCGATCTACATGATGAGCCACTCGGGTGCCCGTGGCTCGCCTGCCCAGATGAAGCAGCTCGC
GGCGATGCGCGGCCTCATGGCCAAGCCGTCGGGCGAGATCATCGAGACCCCGATCATCTCGAACTTCAAGGAAGGTCTGG
ACGTGCTGGAGTACTTCAACTCCACGCACGGTGCCCGTAAGGGCCTCGCCGACACCGCGCTGAAGACCGCCAACTCCGGC
TACCTGACCCGCCGCCTCGTCGACGTGGCGCAGGACGCGGTCATCCGCGAGGTGGATTGCGGCACGACGAGCGGCATCAA
GATGCGCGCCATCGTGGATGCCGGCCAGGTCGTGGCGACGCTCGCCACCCGCATCCTCGGCCGCGCCACGGCGGAGGATC
TGGTGGCCGCCGACGGCACGGTGATCGTCAAGACCGGCGAGACCATCGAGGAGCGGCACCTGCCGGCGATCAACGCCGCC
GGCATCCAGGAGGTGAAGATCCGCTCGGTGCTGGTCTGCGCGACCAAGAGCGGCGTCTGCGCCACCTGCTACGGGCGCGA
CCTCGCCCGCGGCACGCCCGTCAACATGGGCGAGGCCGTCGGCGTCATCGCGGCGCAGTCGATCGGCGAGCCGGGCACGC
AGCTCACGATGCGCACCTTCCACATCGGTGGTGCGGCCCAGATCGCCGACTCGTCGTTCATCGAGTCGAGCTTCGAGGGC
ACGATCAAGATCCGCAACCGGGCCGTGGCCAAGAACACGGACGGGGATCTGATCGCCACCGGCCGCAACGTGGCGGTGGT
CATCGTCGGGTCGGACGGGGTCGAGCGGGCGGTCCACCGCCTGCAGTACGGCGCCAAGCTCCGGGTCGACGAGGGTGACA
AGATCAAGCGCGGGCAGCGGATCGCCGAGTGGGATCCCTACACCCGTCCGATCCTCACCGAGGTGGACGGCATCGTGGCC
TACGAGGATCTGGTCGACGGCCAGTCCATGACCGAGACCACCGACGAGTCGACCGGCATCGCCAAGCGCGTCGTGGTCGA
CTGGCGCGGCTCGGCCCGGACCTCGGACCTGAAGCCCGCGATGGTCGTGGTCGACCGGGACGGCAAGGCGCTCAAGCTGC
CGCGCGGCTCGGACGCCCGCTACTTCCTGCCGGTCGACGCCATCATCGGCTTCGACCCGGGCGCGACGGTCAAGGCCGGC
GACATCCTCGCCCGCGTCTCGACTGACTCGGCCAAGACCCGCGACATCACCGGCGGTCTGCCGCGGGTGGCGGAGCTGTT
CGAGGCACGGCGCCCGAAGGACGCGGCGATCATCGCCGAGAAGTCGGGGACCATCGCGTTCGGCCGCGACTACAAGAACA
AGCGTCGGCTCACGCTGACGCCGCATGACGGCTCGGAGGCGGTCGAGTACCTGATCCCGAAGGGCAAGCACATCCACCTG
CAGGACGGCGACGTGGTCGAGCTCGGCGATTACATCGTCGACGGCAACCCGGCGCCGCACGACATCCTGGCGATCAAGGG
CGTGGAGGAACTCGCGGCCTACCTCGTCAACGAGATCCAGGAGGTCTACCGGCTGCAGGGCGTGTCGATCAACGACAAGC
ACATCGAGGTGATCGTCCGTCAGATGCTGCAGAAGGTCGAGGTGACCGACGGCGGCGACTCGGACATCCTCTCGGGCGAC
CAGATCGATCGCACGGAGCTGACCGACTACAACGAGAAGCTGCTCGCCGAGGGCAAGAAGCCGATCCAGGGCGTCCCGGT
CCTGCTCGGCATCACCAAGGCGTCGCTGCAGACGAAGTCGTTCATCTCGGCGGCCTCGTTCCAGGAGACCACCCGCGTCC
TCACCGAGGCGGCGGTCAACGGAAAGGTCGACACGCTGGAAGGCCTGAAGGAGAACGTCATCGTCGGCTCGCTCATCCCG
GCCGGCACGGGCTCGATGGTGGCGGACATCCGCTCCATCGCCCGCCGCCGCGACGCGATGATCCTGCAGCAGAAGCAGGC
CGAGAGCGGCGCGATGCCGGTCGAGGAGCTTCCGCCGGCCGCTGCCGAGTAA

Upstream 100 bases:

>100_bases
TGGACGACGGTGAGCAGCGCCCGCGCGGGGCGCGGCGCCGGATCTTTTTCAGGACGCGGTGGCCCGGCGCGGGGCTGCCG
GCGTCAACAAGGAGCGGATC

Downstream 100 bases:

>100_bases
GATCACGGGTCGGACTGAGACGAGAGAGGGCGGCCTGCGGGCCGCCCTTTCCTTTTGTGGCGCGCCTTTCTCGGCGCGGC
CGACTTTGCGGGCGCCGCGA

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1403; Mature: 1403

Protein sequence:

>1403_residues
MNQEVMNLFNQQAQPVSFDQIKISISSPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMK
YKGVICEKCGVEVTLARVRRDRMGHIELAAPVAHIWFLKSLPSRIGLLLDMALKDLERILYFESYCVIEPGLTPLKERQL
LSEEEYLRAQEEYGEDSFTAMIGAEAIRRILQELDLDKIANDLREEIAVTTSELKPKKLLKRLKIIEAFQMSGNKPEWMI
LTVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIIRNEKRMLQEAVDALFDNGRRGRVITG
ANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYARLDAKGFSATVKQAK
KLVEKEKPEVWDILDEVIREHPVMLNRAPTLHRLGIQAFEPKLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQL
EARVLMMSTNNILHPANGQPIIVPSQDIVLGLYYLSIVAEGAPGEYKPDNAKNPMQGVYGDMGELEHALAAKAVSLHSKI
KWRWTGIGPDGEPLTKTYETTPGRVILSGALPKHAKVPFDVVNKLMTKKEISAMIDTVYRHCGQKESVIFCDRIMALGFN
HAFKAGISFGKDDMVVPENKWSIVDTTRALVKDYEQQYNDGLITQGEKYNKVVDAWAKCSDKLAAEMMGRISSVQKDEKG
ADKQVNSIYMMSHSGARGSPAQMKQLAAMRGLMAKPSGEIIETPIISNFKEGLDVLEYFNSTHGARKGLADTALKTANSG
YLTRRLVDVAQDAVIREVDCGTTSGIKMRAIVDAGQVVATLATRILGRATAEDLVAADGTVIVKTGETIEERHLPAINAA
GIQEVKIRSVLVCATKSGVCATCYGRDLARGTPVNMGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQIADSSFIESSFEG
TIKIRNRAVAKNTDGDLIATGRNVAVVIVGSDGVERAVHRLQYGAKLRVDEGDKIKRGQRIAEWDPYTRPILTEVDGIVA
YEDLVDGQSMTETTDESTGIAKRVVVDWRGSARTSDLKPAMVVVDRDGKALKLPRGSDARYFLPVDAIIGFDPGATVKAG
DILARVSTDSAKTRDITGGLPRVAELFEARRPKDAAIIAEKSGTIAFGRDYKNKRRLTLTPHDGSEAVEYLIPKGKHIHL
QDGDVVELGDYIVDGNPAPHDILAIKGVEELAAYLVNEIQEVYRLQGVSINDKHIEVIVRQMLQKVEVTDGGDSDILSGD
QIDRTELTDYNEKLLAEGKKPIQGVPVLLGITKASLQTKSFISAASFQETTRVLTEAAVNGKVDTLEGLKENVIVGSLIP
AGTGSMVADIRSIARRRDAMILQQKQAESGAMPVEELPPAAAE

Sequences:

>Translated_1403_residues
MNQEVMNLFNQQAQPVSFDQIKISISSPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMK
YKGVICEKCGVEVTLARVRRDRMGHIELAAPVAHIWFLKSLPSRIGLLLDMALKDLERILYFESYCVIEPGLTPLKERQL
LSEEEYLRAQEEYGEDSFTAMIGAEAIRRILQELDLDKIANDLREEIAVTTSELKPKKLLKRLKIIEAFQMSGNKPEWMI
LTVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIIRNEKRMLQEAVDALFDNGRRGRVITG
ANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYARLDAKGFSATVKQAK
KLVEKEKPEVWDILDEVIREHPVMLNRAPTLHRLGIQAFEPKLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQL
EARVLMMSTNNILHPANGQPIIVPSQDIVLGLYYLSIVAEGAPGEYKPDNAKNPMQGVYGDMGELEHALAAKAVSLHSKI
KWRWTGIGPDGEPLTKTYETTPGRVILSGALPKHAKVPFDVVNKLMTKKEISAMIDTVYRHCGQKESVIFCDRIMALGFN
HAFKAGISFGKDDMVVPENKWSIVDTTRALVKDYEQQYNDGLITQGEKYNKVVDAWAKCSDKLAAEMMGRISSVQKDEKG
ADKQVNSIYMMSHSGARGSPAQMKQLAAMRGLMAKPSGEIIETPIISNFKEGLDVLEYFNSTHGARKGLADTALKTANSG
YLTRRLVDVAQDAVIREVDCGTTSGIKMRAIVDAGQVVATLATRILGRATAEDLVAADGTVIVKTGETIEERHLPAINAA
GIQEVKIRSVLVCATKSGVCATCYGRDLARGTPVNMGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQIADSSFIESSFEG
TIKIRNRAVAKNTDGDLIATGRNVAVVIVGSDGVERAVHRLQYGAKLRVDEGDKIKRGQRIAEWDPYTRPILTEVDGIVA
YEDLVDGQSMTETTDESTGIAKRVVVDWRGSARTSDLKPAMVVVDRDGKALKLPRGSDARYFLPVDAIIGFDPGATVKAG
DILARVSTDSAKTRDITGGLPRVAELFEARRPKDAAIIAEKSGTIAFGRDYKNKRRLTLTPHDGSEAVEYLIPKGKHIHL
QDGDVVELGDYIVDGNPAPHDILAIKGVEELAAYLVNEIQEVYRLQGVSINDKHIEVIVRQMLQKVEVTDGGDSDILSGD
QIDRTELTDYNEKLLAEGKKPIQGVPVLLGITKASLQTKSFISAASFQETTRVLTEAAVNGKVDTLEGLKENVIVGSLIP
AGTGSMVADIRSIARRRDAMILQQKQAESGAMPVEELPPAAAE
>Mature_1403_residues
MNQEVMNLFNQQAQPVSFDQIKISISSPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMK
YKGVICEKCGVEVTLARVRRDRMGHIELAAPVAHIWFLKSLPSRIGLLLDMALKDLERILYFESYCVIEPGLTPLKERQL
LSEEEYLRAQEEYGEDSFTAMIGAEAIRRILQELDLDKIANDLREEIAVTTSELKPKKLLKRLKIIEAFQMSGNKPEWMI
LTVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIIRNEKRMLQEAVDALFDNGRRGRVITG
ANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYARLDAKGFSATVKQAK
KLVEKEKPEVWDILDEVIREHPVMLNRAPTLHRLGIQAFEPKLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQL
EARVLMMSTNNILHPANGQPIIVPSQDIVLGLYYLSIVAEGAPGEYKPDNAKNPMQGVYGDMGELEHALAAKAVSLHSKI
KWRWTGIGPDGEPLTKTYETTPGRVILSGALPKHAKVPFDVVNKLMTKKEISAMIDTVYRHCGQKESVIFCDRIMALGFN
HAFKAGISFGKDDMVVPENKWSIVDTTRALVKDYEQQYNDGLITQGEKYNKVVDAWAKCSDKLAAEMMGRISSVQKDEKG
ADKQVNSIYMMSHSGARGSPAQMKQLAAMRGLMAKPSGEIIETPIISNFKEGLDVLEYFNSTHGARKGLADTALKTANSG
YLTRRLVDVAQDAVIREVDCGTTSGIKMRAIVDAGQVVATLATRILGRATAEDLVAADGTVIVKTGETIEERHLPAINAA
GIQEVKIRSVLVCATKSGVCATCYGRDLARGTPVNMGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQIADSSFIESSFEG
TIKIRNRAVAKNTDGDLIATGRNVAVVIVGSDGVERAVHRLQYGAKLRVDEGDKIKRGQRIAEWDPYTRPILTEVDGIVA
YEDLVDGQSMTETTDESTGIAKRVVVDWRGSARTSDLKPAMVVVDRDGKALKLPRGSDARYFLPVDAIIGFDPGATVKAG
DILARVSTDSAKTRDITGGLPRVAELFEARRPKDAAIIAEKSGTIAFGRDYKNKRRLTLTPHDGSEAVEYLIPKGKHIHL
QDGDVVELGDYIVDGNPAPHDILAIKGVEELAAYLVNEIQEVYRLQGVSINDKHIEVIVRQMLQKVEVTDGGDSDILSGD
QIDRTELTDYNEKLLAEGKKPIQGVPVLLGITKASLQTKSFISAASFQETTRVLTEAAVNGKVDTLEGLKENVIVGSLIP
AGTGSMVADIRSIARRRDAMILQQKQAESGAMPVEELPPAAAE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=925, Percent_Identity=23.7837837837838, Blast_Score=180, Evalue=1e-44,
Organism=Homo sapiens, GI39725938, Length=871, Percent_Identity=24.7990815154994, Blast_Score=158, Evalue=5e-38,
Organism=Homo sapiens, GI103471997, Length=245, Percent_Identity=29.7959183673469, Blast_Score=94, Evalue=1e-18,
Organism=Escherichia coli, GI2367335, Length=1414, Percent_Identity=59.8302687411598, Blast_Score=1655, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=899, Percent_Identity=23.5817575083426, Blast_Score=167, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI25145495, Length=667, Percent_Identity=26.6866566716642, Blast_Score=164, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6320061, Length=885, Percent_Identity=24.8587570621469, Blast_Score=171, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6324690, Length=575, Percent_Identity=27.304347826087, Blast_Score=154, Evalue=7e-38,
Organism=Drosophila melanogaster, GI281360912, Length=853, Percent_Identity=24.0328253223916, Blast_Score=162, Evalue=1e-39,
Organism=Drosophila melanogaster, GI17530899, Length=486, Percent_Identity=26.7489711934156, Blast_Score=154, Evalue=3e-37,
Organism=Drosophila melanogaster, GI17647875, Length=335, Percent_Identity=26.2686567164179, Blast_Score=100, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 154557; Mature: 154557

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQEVMNLFNQQAQPVSFDQIKISISSPEKILSWSYGEIKKPETINYRTFKPERDGLFCA
CCHHHHHHHHCCCCCCEEEEEEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEE
RIFGPIKDYECLCGKYKRMKYKGVICEKCGVEVTLARVRRDRMGHIELAAPVAHIWFLKS
HHHCCCCHHHHHHHHHHHHHCCCEEHHHCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHH
LPSRIGLLLDMALKDLERILYFESYCVIEPGLTPLKERQLLSEEEYLRAQEEYGEDSFTA
HHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHCHHHHHHHHHHCCCCHHHH
MIGAEAIRRILQELDLDKIANDLREEIAVTTSELKPKKLLKRLKIIEAFQMSGNKPEWMI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEE
LTVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIIRNEKRM
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHH
LQEAVDALFDNGRRGRVITGANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVG
HHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEC
PELKLHQCGLPKKMALELFKPFIYARLDAKGFSATVKQAKKLVEKEKPEVWDILDEVIRE
CCCEEHHCCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HPVMLNRAPTLHRLGIQAFEPKLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQL
CCEEECCCCCHHHHCHHHCCCEEECCCEEEEECEEEEEECCCCCCCCEEEEECCEECCCC
EARVLMMSTNNILHPANGQPIIVPSQDIVLGLYYLSIVAEGAPGEYKPDNAKNPMQGVYG
CEEEEEEECCCEEECCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCC
DMGELEHALAAKAVSLHSKIKWRWTGIGPDGEPLTKTYETTPGRVILSGALPKHAKVPFD
CHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHH
VVNKLMTKKEISAMIDTVYRHCGQKESVIFCDRIMALGFNHAFKAGISFGKDDMVVPENK
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCHHHHHCCCCCCCCEECCCCC
WSIVDTTRALVKDYEQQYNDGLITQGEKYNKVVDAWAKCSDKLAAEMMGRISSVQKDEKG
CCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ADKQVNSIYMMSHSGARGSPAQMKQLAAMRGLMAKPSGEIIETPIISNFKEGLDVLEYFN
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHH
STHGARKGLADTALKTANSGYLTRRLVDVAQDAVIREVDCGTTSGIKMRAIVDAGQVVAT
CCCHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCCCCCCCEEEEEEHHHHHHHHH
LATRILGRATAEDLVAADGTVIVKTGETIEERHLPAINAAGIQEVKIRSVLVCATKSGVC
HHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCCCCCCCCHHEEEEEEEEEECCCCCE
ATCYGRDLARGTPVNMGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQIADSSFIESSFEG
EEECCCHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCC
TIKIRNRAVAKNTDGDLIATGRNVAVVIVGSDGVERAVHRLQYGAKLRVDEGDKIKRGQR
EEEEECEEEECCCCCCEEEECCCEEEEEECCCCHHHHHHHHHCCCEEEECCCCHHHCCCC
IAEWDPYTRPILTEVDGIVAYEDLVDGQSMTETTDESTGIAKRVVVDWRGSARTSDLKPA
CCCCCCCCCCHHHHHCCCEEHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCE
MVVVDRDGKALKLPRGSDARYFLPVDAIIGFDPGATVKAGDILARVSTDSAKTRDITGGL
EEEEECCCCEEECCCCCCCEEEEEEHHEEECCCCCCEECCCEEEEECCCCCCCCCCCCCC
PRVAELFEARRPKDAAIIAEKSGTIAFGRDYKNKRRLTLTPHDGSEAVEYLIPKGKHIHL
HHHHHHHHHCCCCCCEEEEECCCCEEECCCCCCCCEEEECCCCCHHHHHHHCCCCCEEEE
QDGDVVELGDYIVDGNPAPHDILAIKGVEELAAYLVNEIQEVYRLQGVSINDKHIEVIVR
CCCCEEEECCEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
QMLQKVEVTDGGDSDILSGDQIDRTELTDYNEKLLAEGKKPIQGVPVLLGITKASLQTKS
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHH
FISAASFQETTRVLTEAAVNGKVDTLEGLKENVIVGSLIPAGTGSMVADIRSIARRRDAM
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHHHHH
ILQQKQAESGAMPVEELPPAAAE
HHHHHHHCCCCCCHHHCCCCCCC
>Mature Secondary Structure
MNQEVMNLFNQQAQPVSFDQIKISISSPEKILSWSYGEIKKPETINYRTFKPERDGLFCA
CCHHHHHHHHCCCCCCEEEEEEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEE
RIFGPIKDYECLCGKYKRMKYKGVICEKCGVEVTLARVRRDRMGHIELAAPVAHIWFLKS
HHHCCCCHHHHHHHHHHHHHCCCEEHHHCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHH
LPSRIGLLLDMALKDLERILYFESYCVIEPGLTPLKERQLLSEEEYLRAQEEYGEDSFTA
HHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHCHHHHHHHHHHCCCCHHHH
MIGAEAIRRILQELDLDKIANDLREEIAVTTSELKPKKLLKRLKIIEAFQMSGNKPEWMI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEE
LTVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIIRNEKRM
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHH
LQEAVDALFDNGRRGRVITGANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVG
HHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEC
PELKLHQCGLPKKMALELFKPFIYARLDAKGFSATVKQAKKLVEKEKPEVWDILDEVIRE
CCCEEHHCCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HPVMLNRAPTLHRLGIQAFEPKLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQL
CCEEECCCCCHHHHCHHHCCCEEECCCEEEEECEEEEEECCCCCCCCEEEEECCEECCCC
EARVLMMSTNNILHPANGQPIIVPSQDIVLGLYYLSIVAEGAPGEYKPDNAKNPMQGVYG
CEEEEEEECCCEEECCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCC
DMGELEHALAAKAVSLHSKIKWRWTGIGPDGEPLTKTYETTPGRVILSGALPKHAKVPFD
CHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHH
VVNKLMTKKEISAMIDTVYRHCGQKESVIFCDRIMALGFNHAFKAGISFGKDDMVVPENK
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCHHHHHCCCCCCCCEECCCCC
WSIVDTTRALVKDYEQQYNDGLITQGEKYNKVVDAWAKCSDKLAAEMMGRISSVQKDEKG
CCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ADKQVNSIYMMSHSGARGSPAQMKQLAAMRGLMAKPSGEIIETPIISNFKEGLDVLEYFN
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHH
STHGARKGLADTALKTANSGYLTRRLVDVAQDAVIREVDCGTTSGIKMRAIVDAGQVVAT
CCCHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCCCCCCCEEEEEEHHHHHHHHH
LATRILGRATAEDLVAADGTVIVKTGETIEERHLPAINAAGIQEVKIRSVLVCATKSGVC
HHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCCCCCCCCHHEEEEEEEEEECCCCCE
ATCYGRDLARGTPVNMGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQIADSSFIESSFEG
EEECCCHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCC
TIKIRNRAVAKNTDGDLIATGRNVAVVIVGSDGVERAVHRLQYGAKLRVDEGDKIKRGQR
EEEEECEEEECCCCCCEEEECCCEEEEEECCCCHHHHHHHHHCCCEEEECCCCHHHCCCC
IAEWDPYTRPILTEVDGIVAYEDLVDGQSMTETTDESTGIAKRVVVDWRGSARTSDLKPA
CCCCCCCCCCHHHHHCCCEEHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCE
MVVVDRDGKALKLPRGSDARYFLPVDAIIGFDPGATVKAGDILARVSTDSAKTRDITGGL
EEEEECCCCEEECCCCCCCEEEEEEHHEEECCCCCCEECCCEEEEECCCCCCCCCCCCCC
PRVAELFEARRPKDAAIIAEKSGTIAFGRDYKNKRRLTLTPHDGSEAVEYLIPKGKHIHL
HHHHHHHHHCCCCCCEEEEECCCCEEECCCCCCCCEEEECCCCCHHHHHHHCCCCCEEEE
QDGDVVELGDYIVDGNPAPHDILAIKGVEELAAYLVNEIQEVYRLQGVSINDKHIEVIVR
CCCCEEEECCEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
QMLQKVEVTDGGDSDILSGDQIDRTELTDYNEKLLAEGKKPIQGVPVLLGITKASLQTKS
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHH
FISAASFQETTRVLTEAAVNGKVDTLEGLKENVIVGSLIPAGTGSMVADIRSIARRRDAM
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHHHHH
ILQQKQAESGAMPVEELPPAAAE
HHHHHHHCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA