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The map label for this gene is rpoB [H]

Identifier: 170750237

GI number: 170750237

Start: 4087374

End: 4091498

Strand: Reverse

Name: rpoB [H]

Synonym: Mrad2831_3839

Alternate gene names: 170750237

Gene position: 4091498-4087374 (Counterclockwise)

Preceding gene: 170750238

Following gene: 170750236

Centisome position: 67.32

GC content: 67.27

Gene sequence:

>4125_bases
ATGGCCAACACGCTGGTCGGTCGCAAGCGCATTCGGAAGTTCTTCGGCAAGATCAAGGAAGTTGCCGAGATGCCGAACCT
CATCGAGGTTCAGAAGGCGTCCTACGACCAGTTCCTGATGGTCGACGAGCCCGAGGGCGGGCGCGCCGACGAGGGGCTGC
AGAGCGTGTTCAAGTCGGTGTTCCCGATCTCCGACTTCGCCTCCACGGCGCTGCTGGAGTTCGTGCGCTACACCTTCGAG
GCGCCCAAGTACGACGTGGACGAGTGCCGCCAGCGCGGCATCACCTTCGCGGCGCCGCTGAAGGTCACGCTGCGCCTCAT
CGTGTTCGATGTCGATCCCGACACCCAGGCCAAGTCGGTCAAGGACATCAAGGAGCAGGACGTCTACATGGGCGACATGC
CCCTGATGACGGAGAACGGCACCTTCATCGTCAACGGCACCGAGCGCGTCATCGTCTCGCAGATGCACCGCTCGCCGGGC
GTGTTCTTCGACCACGACAAGGGCAAGACCCACTCCTCGGGCAAGCTCCTGTTCGCCGCCCGCATCATCCCGTACCGGGG
CTCCTGGCTCGACGTCGAGTTCGACGCCAAGGACATCGTGCACGTCCGCATCGACCGGAAGCGCAAGCTGCCGGCGACGT
CGCTGCTCTACGCGCTCGGCCTCGACGGCGAGGAGATCCTGTCGACCTTCTACAACAAGGTCGTCTACGACCGGGACGGC
GCCGACTGGCGCGTGCCGTTCGACGCCGAGCGCATGAAGGGCATGAAGGCCACCGTCGACCTGATCGACGCCGATTCCGG
CGAGGTCGTGCTCGAGGCCGGCAAGAAGCTCAACGCCCGCAACGCCCGCCAGATCACCGAGAAGGGCACCAAGTTCCTCA
AGGCGACCGACGAGGATCTCGTCGGCCAGTACGTCGCCGAGGACCTCGTCAACGCCCAGACCGGTGAGATCTGGGCCGAG
GCCGGCGAGGAGGTCACCGACAAGCTCCTGAAGAGCCTGGAGGAGGTCGGGATCACCGAGCTGCCGGTGCTCGACATCGA
CCACGTCAACATCGGCCCGTACATCCGCAACACGCTGGCGGTGGACAAGAATTCCAACCGCGAGGGCGCGCTGTTCGACA
TCTACCGGGTCATGCGCCCGGGCGAGCCGCCGACCCTCGAGACCGCCGAGGCGATGTTCCACTCGCTGTTCTTCGATTCC
GAGCGCTACGACCTCTCGGCGGTCGGCCGCGTGAAGATGAACATGCGTCTCGACCTCGACGCCGCCGACACCGTGCGCAC
GCTCCGCAAGGAGGACATGCTGGCGGTGGTCAAGGCGCTCGTGGAGCTGCGCGACGGCAAGGGCGAGGTCGACGACATCG
ACCACCTCGGCAACCGCCGCGTCCGCTCGGTGGGCGAGCTCATGGAGAACCAGTACCGCCTGGGCCTCCTGCGCATGGAG
CGCGCCATCCGCGAGCGCATGAGCCAGGTCGACATCGACACGGTCATGCCGCAGGACCTGATCAACGCGAAGCCCGCGGC
CGCGGCCGTGCGCGAGTTCTTCGGCTCGTCGCAGCTGTCGCAGTTCATGGACCAGACCAACCCGCTCTCCGAGGTGACGC
ACAAGCGCCGCCTCTCGGCCCTCGGCCCGGGCGGTCTGACCCGCGAGCGCGCCGGCTTCGAGGTGCGCGACGTGCACCCG
ACGCACTACGGCCGCATCTGCCCGATCGAGACGCCGGAAGGCCCGAACATCGGCCTGATCAACTCGCTCGCGACCTTCGC
GCGGGTGAACAAGTACGGCTTCATCGAGACCCCGTTCCGCCGCGTGCGCGACGGCGTGGTCACCGACGAGGTCGCCTACC
TCTCGGCCATGGAGGAGGCGAAGTACTACGTCGCCCAGGCGAACGCCCAGATGGACGAGAACCGCAAGCTCACGGAGGAC
CTCGTGGTCTGCCGCCGGGCCGGCGAGGTGATCGTCGTGGGTCCCGAGCGCGTCGACCTCATGGACGTGTCGCCGAAGCA
GCTCGTCTCGGTGGCCGCGGCGCTGATCCCGTTCCTCGAGAACGACGACGCCAACCGCGCGCTCATGGGCTCGAACATGC
AGCGCCAGGCGGTGCCGCTGGTCCGCGCCGACGCCCCGTTCGTGGGCACCGGCATGGAGGCGGTGGTCGCCCGGGATTCC
GGCGCCGCCATCGCGGCCCGCCGGGCCGGCATCATCGATCAGGTGGACGCCACCCGTATCGTCATCCGCGCCACCGAGGA
GGCCGACGCCAACAAGCCCGGCGTCGACATCTACCGCCTGCAGAAGTTCCAGCGCTCCAACCAGTCGACCTGCATCACGC
AGAAGCCGCTGGTCCGCGTCGGCGAGTTCGTGAAGAAGGGCGAGATCATCGCCGACGGTCCCTCGACCGAGTTCGGCGAG
CTGGCGCTCGGCCGGAACGTGCTCGTCGCGTTCATGCCGTGGAACGGCTACAACTTCGAGGACTCGATCCTGCTCTCCGA
GCGGATCGTGAAGGATGACGTGTTCACCTCGATCCACATCGAGGAGTTCGAGGTGATGGCCCGCGACACCAAGCTCGGGC
CGGAGGAGATCACCCGCGACATCCCGAACGTCTCCGAGGAGGCGCTCAAGAACCTCGACGAGGCCGGCATCGTCTACATC
GGTGCCGAGGTGAATGCCGGCGACATCCTCGTCGGCAAGATCACCCCGAAGGGCGAGAGCCCGATGACGCCGGAGGAGAA
GCTGCTCCGCGCCATCTTCGGCGAGAAGGCCTCGGACGTGCGCGACACCTCGCTGCGGGTGCCGCCGGGCGTCACCGGCA
CGATCGTCGAGGTCCGAGTGTTCAACCGCCACGGCGTCGACAAGGACGAGCGCGCCCAGGCGATCGAGCGCGAGGAGATC
GAGCGGCTCGCCAAGGACCGCGACGACGAGCAGGCGATCCTCGACCGCAACACCTACGCCCGCCTGGCGGACGTGCTGAT
CGGTCAGGCGCCGGTGGCCGGCCCGAAGGGCTTCAAGAAGGACACCACGCTCACCCGCGAGCTGATCAACGACTACCCGC
GCTCGCAGTGGTGGCAGTTCGCCGTCATCGACGACCGTCTCATGACCGAGATGGAGGCGATGCAGAAGCAGTACGACGAG
TCGAAGAAGCGCCTCGAGCAGCGCTTCCTCGACAAGGTCGAGAAGCTGCAGCGCGGCGACGAGCTGCCCCCCGGCGTCAT
GAAGATGGTCAAGGTCTTCGTGGCGGTGAAGCGCAAGATCCAGCCGGGCGACAAGATGGCCGGCCGTCACGGCAACAAGG
GTGTCGTGTCGCGGATCGTGCCGATCGAGGACATGCCGTTCCTGGAAGACGGGACGCACGCCGACATCGTGCTCAACCCG
CTGGGCGTGCCCTCGCGCATGAACGTCGGGCAGATCCTGGAGACGCACCTGGGCTGGGCGGCTGCGGGCCTGGGTCGCAA
GGTGTCGAAGGCGGTGGATGCCTATCTGAAGACCCAGGACATCGCGCCGCTGCGGGAGGAGATGAAGGCGATCTACTCCC
CCGGCGAGCTCGACGGCCTGACGGACGAGGAGCTGGCCGAGGCCGGCAACAACGTCCGCCGCGGCGTGCCGATGGCCACC
CCGGTCTTCAACGGCGCCAAGGAGGCCGACATCGAGCAGATGCTGGAGATGGCCGGGCTGGACCGCTCGGCGCAGTCGAC
GCTCTACGACGGGCGCACCGGCGAGCCCTTCGACCGCAAGGTCACCATGGGCTACATCTACATGCTGAAGCTCCACCACC
TCGTGGACGACAAGATCCACGCGCGCTCGATCGGCCCGTACTCGCTCGTCACCCAGCAGCCGCTGGGCGGCAAGGCGCAG
TTCGGCGGCCAGCGCTTCGGCGAGATGGAGGTCTGGGCGCTCGAGGCCTACGGCGCGGCCTACACGCTGCAGGAGATGCT
CACGGTGAAGTCGGACGACGTGGCCGGCCGCACCAAGGTCTACGAGGCGATCGTCCGCGGCGACGACACGTTCGAGGCCG
GCATCCCCGAGTCGTTCAACGTGCTCGTCAAGGAGATGCGCTCGCTCGGCCTCAACGTCGAGCTCACCTCCTCCAAGAAG
GCGGCCAACGACCAGCTGGAGCCGCCGGCGGACGCGGCCGAGTAA

Upstream 100 bases:

>100_bases
GTGGCGCGGCTCGGCGGGGCGCGCGTCACGGCCCGGTGCGGGAGGTCCCTTTCGGGAACGCTTCCCCGGGCGCGAGGCAC
GCGGGTAGGAGCGAGGTCAC

Downstream 100 bases:

>100_bases
GAGAGAACCACACCTCCCGTGGCGGCGGGTCACCGCCGCCACGGTCGAGCGGGAAGGGGAGGGGCCTTCCGAGGTTGGAC
GACGGTGAGCAGCGCCCGCG

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1374; Mature: 1373

Protein sequence:

>1374_residues
MANTLVGRKRIRKFFGKIKEVAEMPNLIEVQKASYDQFLMVDEPEGGRADEGLQSVFKSVFPISDFASTALLEFVRYTFE
APKYDVDECRQRGITFAAPLKVTLRLIVFDVDPDTQAKSVKDIKEQDVYMGDMPLMTENGTFIVNGTERVIVSQMHRSPG
VFFDHDKGKTHSSGKLLFAARIIPYRGSWLDVEFDAKDIVHVRIDRKRKLPATSLLYALGLDGEEILSTFYNKVVYDRDG
ADWRVPFDAERMKGMKATVDLIDADSGEVVLEAGKKLNARNARQITEKGTKFLKATDEDLVGQYVAEDLVNAQTGEIWAE
AGEEVTDKLLKSLEEVGITELPVLDIDHVNIGPYIRNTLAVDKNSNREGALFDIYRVMRPGEPPTLETAEAMFHSLFFDS
ERYDLSAVGRVKMNMRLDLDAADTVRTLRKEDMLAVVKALVELRDGKGEVDDIDHLGNRRVRSVGELMENQYRLGLLRME
RAIRERMSQVDIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHP
THYGRICPIETPEGPNIGLINSLATFARVNKYGFIETPFRRVRDGVVTDEVAYLSAMEEAKYYVAQANAQMDENRKLTED
LVVCRRAGEVIVVGPERVDLMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLVRADAPFVGTGMEAVVARDS
GAAIAARRAGIIDQVDATRIVIRATEEADANKPGVDIYRLQKFQRSNQSTCITQKPLVRVGEFVKKGEIIADGPSTEFGE
LALGRNVLVAFMPWNGYNFEDSILLSERIVKDDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIVYI
GAEVNAGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSLRVPPGVTGTIVEVRVFNRHGVDKDERAQAIEREEI
ERLAKDRDDEQAILDRNTYARLADVLIGQAPVAGPKGFKKDTTLTRELINDYPRSQWWQFAVIDDRLMTEMEAMQKQYDE
SKKRLEQRFLDKVEKLQRGDELPPGVMKMVKVFVAVKRKIQPGDKMAGRHGNKGVVSRIVPIEDMPFLEDGTHADIVLNP
LGVPSRMNVGQILETHLGWAAAGLGRKVSKAVDAYLKTQDIAPLREEMKAIYSPGELDGLTDEELAEAGNNVRRGVPMAT
PVFNGAKEADIEQMLEMAGLDRSAQSTLYDGRTGEPFDRKVTMGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQ
FGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELTSSKK
AANDQLEPPADAAE

Sequences:

>Translated_1374_residues
MANTLVGRKRIRKFFGKIKEVAEMPNLIEVQKASYDQFLMVDEPEGGRADEGLQSVFKSVFPISDFASTALLEFVRYTFE
APKYDVDECRQRGITFAAPLKVTLRLIVFDVDPDTQAKSVKDIKEQDVYMGDMPLMTENGTFIVNGTERVIVSQMHRSPG
VFFDHDKGKTHSSGKLLFAARIIPYRGSWLDVEFDAKDIVHVRIDRKRKLPATSLLYALGLDGEEILSTFYNKVVYDRDG
ADWRVPFDAERMKGMKATVDLIDADSGEVVLEAGKKLNARNARQITEKGTKFLKATDEDLVGQYVAEDLVNAQTGEIWAE
AGEEVTDKLLKSLEEVGITELPVLDIDHVNIGPYIRNTLAVDKNSNREGALFDIYRVMRPGEPPTLETAEAMFHSLFFDS
ERYDLSAVGRVKMNMRLDLDAADTVRTLRKEDMLAVVKALVELRDGKGEVDDIDHLGNRRVRSVGELMENQYRLGLLRME
RAIRERMSQVDIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHP
THYGRICPIETPEGPNIGLINSLATFARVNKYGFIETPFRRVRDGVVTDEVAYLSAMEEAKYYVAQANAQMDENRKLTED
LVVCRRAGEVIVVGPERVDLMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLVRADAPFVGTGMEAVVARDS
GAAIAARRAGIIDQVDATRIVIRATEEADANKPGVDIYRLQKFQRSNQSTCITQKPLVRVGEFVKKGEIIADGPSTEFGE
LALGRNVLVAFMPWNGYNFEDSILLSERIVKDDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIVYI
GAEVNAGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSLRVPPGVTGTIVEVRVFNRHGVDKDERAQAIEREEI
ERLAKDRDDEQAILDRNTYARLADVLIGQAPVAGPKGFKKDTTLTRELINDYPRSQWWQFAVIDDRLMTEMEAMQKQYDE
SKKRLEQRFLDKVEKLQRGDELPPGVMKMVKVFVAVKRKIQPGDKMAGRHGNKGVVSRIVPIEDMPFLEDGTHADIVLNP
LGVPSRMNVGQILETHLGWAAAGLGRKVSKAVDAYLKTQDIAPLREEMKAIYSPGELDGLTDEELAEAGNNVRRGVPMAT
PVFNGAKEADIEQMLEMAGLDRSAQSTLYDGRTGEPFDRKVTMGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQ
FGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELTSSKK
AANDQLEPPADAAE
>Mature_1373_residues
ANTLVGRKRIRKFFGKIKEVAEMPNLIEVQKASYDQFLMVDEPEGGRADEGLQSVFKSVFPISDFASTALLEFVRYTFEA
PKYDVDECRQRGITFAAPLKVTLRLIVFDVDPDTQAKSVKDIKEQDVYMGDMPLMTENGTFIVNGTERVIVSQMHRSPGV
FFDHDKGKTHSSGKLLFAARIIPYRGSWLDVEFDAKDIVHVRIDRKRKLPATSLLYALGLDGEEILSTFYNKVVYDRDGA
DWRVPFDAERMKGMKATVDLIDADSGEVVLEAGKKLNARNARQITEKGTKFLKATDEDLVGQYVAEDLVNAQTGEIWAEA
GEEVTDKLLKSLEEVGITELPVLDIDHVNIGPYIRNTLAVDKNSNREGALFDIYRVMRPGEPPTLETAEAMFHSLFFDSE
RYDLSAVGRVKMNMRLDLDAADTVRTLRKEDMLAVVKALVELRDGKGEVDDIDHLGNRRVRSVGELMENQYRLGLLRMER
AIRERMSQVDIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPT
HYGRICPIETPEGPNIGLINSLATFARVNKYGFIETPFRRVRDGVVTDEVAYLSAMEEAKYYVAQANAQMDENRKLTEDL
VVCRRAGEVIVVGPERVDLMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLVRADAPFVGTGMEAVVARDSG
AAIAARRAGIIDQVDATRIVIRATEEADANKPGVDIYRLQKFQRSNQSTCITQKPLVRVGEFVKKGEIIADGPSTEFGEL
ALGRNVLVAFMPWNGYNFEDSILLSERIVKDDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIVYIG
AEVNAGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSLRVPPGVTGTIVEVRVFNRHGVDKDERAQAIEREEIE
RLAKDRDDEQAILDRNTYARLADVLIGQAPVAGPKGFKKDTTLTRELINDYPRSQWWQFAVIDDRLMTEMEAMQKQYDES
KKRLEQRFLDKVEKLQRGDELPPGVMKMVKVFVAVKRKIQPGDKMAGRHGNKGVVSRIVPIEDMPFLEDGTHADIVLNPL
GVPSRMNVGQILETHLGWAAAGLGRKVSKAVDAYLKTQDIAPLREEMKAIYSPGELDGLTDEELAEAGNNVRRGVPMATP
VFNGAKEADIEQMLEMAGLDRSAQSTLYDGRTGEPFDRKVTMGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQF
GGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELTSSKKA
ANDQLEPPADAAE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI238908505, Length=301, Percent_Identity=31.5614617940199, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI238908503, Length=301, Percent_Identity=31.5614617940199, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI33469941, Length=320, Percent_Identity=29.6875, Blast_Score=131, Evalue=6e-30,
Organism=Homo sapiens, GI212286172, Length=320, Percent_Identity=29.6875, Blast_Score=130, Evalue=7e-30,
Organism=Homo sapiens, GI4505941, Length=245, Percent_Identity=32.2448979591837, Blast_Score=120, Evalue=7e-27,
Organism=Escherichia coli, GI1790419, Length=1364, Percent_Identity=58.4310850439883, Blast_Score=1624, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=293, Percent_Identity=30.0341296928328, Blast_Score=124, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17506623, Length=236, Percent_Identity=33.4745762711864, Blast_Score=123, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17552304, Length=245, Percent_Identity=31.8367346938775, Blast_Score=119, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6324781, Length=293, Percent_Identity=32.0819112627986, Blast_Score=135, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6325267, Length=246, Percent_Identity=33.3333333333333, Blast_Score=126, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6324725, Length=310, Percent_Identity=28.0645161290323, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17647877, Length=244, Percent_Identity=34.0163934426229, Blast_Score=129, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17136446, Length=247, Percent_Identity=34.0080971659919, Blast_Score=116, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17136444, Length=245, Percent_Identity=31.4285714285714, Blast_Score=116, Evalue=1e-25,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 153096; Mature: 152965

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTLVGRKRIRKFFGKIKEVAEMPNLIEVQKASYDQFLMVDEPEGGRADEGLQSVFKSV
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEHHHCCCCCEEEEECCCCCCCHHHHHHHHHHH
FPISDFASTALLEFVRYTFEAPKYDVDECRQRGITFAAPLKVTLRLIVFDVDPDTQAKSV
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEECCEEEEEEEEEECCCCCHHHHH
KDIKEQDVYMGDMPLMTENGTFIVNGTERVIVSQMHRSPGVFFDHDKGKTHSSGKLLFAA
HHHHHHCCEECCCCEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEE
RIIPYRGSWLDVEFDAKDIVHVRIDRKRKLPATSLLYALGLDGEEILSTFYNKVVYDRDG
EEECCCCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHEECCCC
ADWRVPFDAERMKGMKATVDLIDADSGEVVLEAGKKLNARNARQITEKGTKFLKATDEDL
CCEECCCCHHHHCCCEEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHH
VGQYVAEDLVNAQTGEIWAEAGEEVTDKLLKSLEEVGITELPVLDIDHVNIGPYIRNTLA
HHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHEEE
VDKNSNREGALFDIYRVMRPGEPPTLETAEAMFHSLFFDSERYDLSAVGRVKMNMRLDLD
ECCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHEECEEEEEEEECCC
AADTVRTLRKEDMLAVVKALVELRDGKGEVDDIDHLGNRRVRSVGELMENQYRLGLLRME
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
RAIRERMSQVDIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEVTHKRRLSA
HHHHHHHHHCCHHHCCCHHHHCCCHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHH
LGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIETPFR
CCCCCCCHHHCCCEEEECCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHH
RVRDGVVTDEVAYLSAMEEAKYYVAQANAQMDENRKLTEDLVVCRRAGEVIVVGPERVDL
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCEEE
MDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLVRADAPFVGTGMEAVVARDS
ECCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHCCCEEECCCCCCCCCCEEEEECCC
GAAIAARRAGIIDQVDATRIVIRATEEADANKPGVDIYRLQKFQRSNQSTCITQKPLVRV
CCCHHHHHCCCHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHH
GEFVKKGEIIADGPSTEFGELALGRNVLVAFMPWNGYNFEDSILLSERIVKDDVFTSIHI
HHHHHCCCEEECCCCCCHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHEEEH
EEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIVYIGAEVNAGDILVGKITPKGES
HHHHHHHHHCCCCHHHHHHHCCCCHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCC
PMTPEEKLLRAIFGEKASDVRDTSLRVPPGVTGTIVEVRVFNRHGVDKDERAQAIEREEI
CCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHH
ERLAKDRDDEQAILDRNTYARLADVLIGQAPVAGPKGFKKDTTLTRELINDYPRSQWWQF
HHHHHCCCCHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEE
AVIDDRLMTEMEAMQKQYDESKKRLEQRFLDKVEKLQRGDELPPGVMKMVKVFVAVKRKI
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
QPGDKMAGRHGNKGVVSRIVPIEDMPFLEDGTHADIVLNPLGVPSRMNVGQILETHLGWA
CCCHHHCCCCCCCCHHHEECCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHH
AAGLGRKVSKAVDAYLKTQDIAPLREEMKAIYSPGELDGLTDEELAEAGNNVRRGVPMAT
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHCCCCCCC
PVFNGAKEADIEQMLEMAGLDRSAQSTLYDGRTGEPFDRKVTMGYIYMLKLHHLVDDKIH
CCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
ARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKV
HCCCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEEHHCHHHHHHHHHHHCCCCCCHHHHH
YEAIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELTSSKKAANDQLEPPADAAE
HHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ANTLVGRKRIRKFFGKIKEVAEMPNLIEVQKASYDQFLMVDEPEGGRADEGLQSVFKSV
CCCHHHHHHHHHHHHHHHHHHHCCCCEEHHHCCCCCEEEEECCCCCCCHHHHHHHHHHH
FPISDFASTALLEFVRYTFEAPKYDVDECRQRGITFAAPLKVTLRLIVFDVDPDTQAKSV
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEECCEEEEEEEEEECCCCCHHHHH
KDIKEQDVYMGDMPLMTENGTFIVNGTERVIVSQMHRSPGVFFDHDKGKTHSSGKLLFAA
HHHHHHCCEECCCCEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEE
RIIPYRGSWLDVEFDAKDIVHVRIDRKRKLPATSLLYALGLDGEEILSTFYNKVVYDRDG
EEECCCCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHEECCCC
ADWRVPFDAERMKGMKATVDLIDADSGEVVLEAGKKLNARNARQITEKGTKFLKATDEDL
CCEECCCCHHHHCCCEEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHH
VGQYVAEDLVNAQTGEIWAEAGEEVTDKLLKSLEEVGITELPVLDIDHVNIGPYIRNTLA
HHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHEEE
VDKNSNREGALFDIYRVMRPGEPPTLETAEAMFHSLFFDSERYDLSAVGRVKMNMRLDLD
ECCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHEECEEEEEEEECCC
AADTVRTLRKEDMLAVVKALVELRDGKGEVDDIDHLGNRRVRSVGELMENQYRLGLLRME
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
RAIRERMSQVDIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEVTHKRRLSA
HHHHHHHHHCCHHHCCCHHHHCCCHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHH
LGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIETPFR
CCCCCCCHHHCCCEEEECCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHH
RVRDGVVTDEVAYLSAMEEAKYYVAQANAQMDENRKLTEDLVVCRRAGEVIVVGPERVDL
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCEEE
MDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLVRADAPFVGTGMEAVVARDS
ECCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHCCCEEECCCCCCCCCCEEEEECCC
GAAIAARRAGIIDQVDATRIVIRATEEADANKPGVDIYRLQKFQRSNQSTCITQKPLVRV
CCCHHHHHCCCHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHH
GEFVKKGEIIADGPSTEFGELALGRNVLVAFMPWNGYNFEDSILLSERIVKDDVFTSIHI
HHHHHCCCEEECCCCCCHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHEEEH
EEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIVYIGAEVNAGDILVGKITPKGES
HHHHHHHHHCCCCHHHHHHHCCCCHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCC
PMTPEEKLLRAIFGEKASDVRDTSLRVPPGVTGTIVEVRVFNRHGVDKDERAQAIEREEI
CCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHH
ERLAKDRDDEQAILDRNTYARLADVLIGQAPVAGPKGFKKDTTLTRELINDYPRSQWWQF
HHHHHCCCCHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEE
AVIDDRLMTEMEAMQKQYDESKKRLEQRFLDKVEKLQRGDELPPGVMKMVKVFVAVKRKI
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
QPGDKMAGRHGNKGVVSRIVPIEDMPFLEDGTHADIVLNPLGVPSRMNVGQILETHLGWA
CCCHHHCCCCCCCCHHHEECCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHH
AAGLGRKVSKAVDAYLKTQDIAPLREEMKAIYSPGELDGLTDEELAEAGNNVRRGVPMAT
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHCCCCCCC
PVFNGAKEADIEQMLEMAGLDRSAQSTLYDGRTGEPFDRKVTMGYIYMLKLHHLVDDKIH
CCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
ARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKV
HCCCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEEHHCHHHHHHHHHHHCCCCCCHHHHH
YEAIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELTSSKKAANDQLEPPADAAE
HHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA