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The map label for this gene is ltrA [H]

Identifier: 170750230

GI number: 170750230

Start: 4077320

End: 4078192

Strand: Direct

Name: ltrA [H]

Synonym: Mrad2831_3832

Alternate gene names: 170750230

Gene position: 4077320-4078192 (Clockwise)

Preceding gene: 170750228

Following gene: 170750232

Centisome position: 67.09

GC content: 75.83

Gene sequence:

>873_bases
GTGGAGCTCGACTGGGACGACTTCCGGTTCGTGAAGGCGGTGGCCGACCGGGGCGGCCTGACCGCGGCGTCGGCCGAGCT
CGGCATCAACCACTCGACGGCATTCCGGCGTCTCGCCGCCCTGGAGGCGCGGCTCGGCACGCGCCTGTTCGAGCGGCTGC
GCACGGGCTACGTGCCGACCGCGGCCGGGCAGGCGATGGTCGACGCGGCCGGGCGCATCGAGACGGACGTGACGCGGTTC
GCCCGCGCGGTGGCGGGACAGGGCGAGACGCCGTCCGGCGAGCTGCGGGTGACCGCACCGGCGGGCTTCGCCGCCGAGCT
GCTGATGCCGATGCTGGCGAGCTTCGCGGAGCGCTACCCGGAGATCCGGATCGAGCTCATCCTCGCGGAGGCGACCCTCA
ACCTCTCCCGGCGCGACGCCGACGTGGCGATCCGGATCAGCCGGGAACCGAGCGAGACCCTGGTCGGGCGTCGACTGGCC
CTCACCGCGTGGGCGGTCTACGGCCGCGCCGACCGCGCCTACGGCGACCTGGCCCGGGAGGCCTGGATCAGCCCGGGGCC
GCTGGTGGCGGGGGGCTCGCTCACGCGGTTCGTGGAGGCGCGGGCGCCGTCCGACCGTGTCCGCCTGCGGATCAACGCGG
TGCCGGGCCTGGAGGCGGCGGTCGAGGCCGGCCTCGGCATCGGCCCGCTCCCCTGCTTCACGGCCGACGTGAACCCGGCG
CTGCGCCGCCTGTCCGGGCCGCACCCCGAACTCGGGGCGGACCTCTGGATCCTGACGCATCCGGACCTGCGCCACGCGGC
GCGTGTCCGGGCCTTCATGGAGCACGTCGCCGAGGCGCTGCTGCCGCTGCGGGCGCGCTTCGAGGGCCGCTGA

Upstream 100 bases:

>100_bases
GAATCGTCGGCCGGCGGATGGCCCCTGCATCGCGCATTTGCCGTCTTGCAAGAATGCCCCGACATGCAAGACTAACCTTG
CGCAGATGCAAGGATCCGGC

Downstream 100 bases:

>100_bases
TCCGGCTCAGCGGATCTCGAGCACCTCGACCTCGTGGCCGTTCACCTCGACCACGTCGCCGATCGTCTTGCCGGTGATCG
CCCGGGCGAGGGGCGCCACG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MELDWDDFRFVKAVADRGGLTAASAELGINHSTAFRRLAALEARLGTRLFERLRTGYVPTAAGQAMVDAAGRIETDVTRF
ARAVAGQGETPSGELRVTAPAGFAAELLMPMLASFAERYPEIRIELILAEATLNLSRRDADVAIRISREPSETLVGRRLA
LTAWAVYGRADRAYGDLAREAWISPGPLVAGGSLTRFVEARAPSDRVRLRINAVPGLEAAVEAGLGIGPLPCFTADVNPA
LRRLSGPHPELGADLWILTHPDLRHAARVRAFMEHVAEALLPLRARFEGR

Sequences:

>Translated_290_residues
MELDWDDFRFVKAVADRGGLTAASAELGINHSTAFRRLAALEARLGTRLFERLRTGYVPTAAGQAMVDAAGRIETDVTRF
ARAVAGQGETPSGELRVTAPAGFAAELLMPMLASFAERYPEIRIELILAEATLNLSRRDADVAIRISREPSETLVGRRLA
LTAWAVYGRADRAYGDLAREAWISPGPLVAGGSLTRFVEARAPSDRVRLRINAVPGLEAAVEAGLGIGPLPCFTADVNPA
LRRLSGPHPELGADLWILTHPDLRHAARVRAFMEHVAEALLPLRARFEGR
>Mature_290_residues
MELDWDDFRFVKAVADRGGLTAASAELGINHSTAFRRLAALEARLGTRLFERLRTGYVPTAAGQAMVDAAGRIETDVTRF
ARAVAGQGETPSGELRVTAPAGFAAELLMPMLASFAERYPEIRIELILAEATLNLSRRDADVAIRISREPSETLVGRRLA
LTAWAVYGRADRAYGDLAREAWISPGPLVAGGSLTRFVEARAPSDRVRLRINAVPGLEAAVEAGLGIGPLPCFTADVNPA
LRRLSGPHPELGADLWILTHPDLRHAARVRAFMEHVAEALLPLRARFEGR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081978, Length=155, Percent_Identity=28.3870967741935, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786401, Length=145, Percent_Identity=28.9655172413793, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1789440, Length=154, Percent_Identity=25.974025974026, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787589, Length=147, Percent_Identity=26.530612244898, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787128, Length=147, Percent_Identity=27.891156462585, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31433; Mature: 31433

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELDWDDFRFVKAVADRGGLTAASAELGINHSTAFRRLAALEARLGTRLFERLRTGYVPT
CCCCHHHHHHHHHHHHCCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AAGQAMVDAAGRIETDVTRFARAVAGQGETPSGELRVTAPAGFAAELLMPMLASFAERYP
CCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCC
EIRIELILAEATLNLSRRDADVAIRISREPSETLVGRRLALTAWAVYGRADRAYGDLARE
CEEEEEEEEEHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AWISPGPLVAGGSLTRFVEARAPSDRVRLRINAVPGLEAAVEAGLGIGPLPCFTADVNPA
HCCCCCCEEECCCHHHHHHHCCCCCEEEEEEECCCCHHHHHHCCCCCCCCCCEECCCCHH
LRRLSGPHPELGADLWILTHPDLRHAARVRAFMEHVAEALLPLRARFEGR
HHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MELDWDDFRFVKAVADRGGLTAASAELGINHSTAFRRLAALEARLGTRLFERLRTGYVPT
CCCCHHHHHHHHHHHHCCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AAGQAMVDAAGRIETDVTRFARAVAGQGETPSGELRVTAPAGFAAELLMPMLASFAERYP
CCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCC
EIRIELILAEATLNLSRRDADVAIRISREPSETLVGRRLALTAWAVYGRADRAYGDLARE
CEEEEEEEEEHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AWISPGPLVAGGSLTRFVEARAPSDRVRLRINAVPGLEAAVEAGLGIGPLPCFTADVNPA
HCCCCCCEEECCCHHHHHHHCCCCCEEEEEEECCCCHHHHHHCCCCCCCCCCEECCCCHH
LRRLSGPHPELGADLWILTHPDLRHAARVRAFMEHVAEALLPLRARFEGR
HHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]