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The map label for this gene is ywlC [H]

Identifier: 170750228

GI number: 170750228

Start: 4075452

End: 4076450

Strand: Direct

Name: ywlC [H]

Synonym: Mrad2831_3830

Alternate gene names: 170750228

Gene position: 4075452-4076450 (Clockwise)

Preceding gene: 170750222

Following gene: 170750230

Centisome position: 67.05

GC content: 79.48

Gene sequence:

>999_bases
ATGAATGATCCCGGGTCAACGGTCCCGTCCGCGACCCGGCGGCTTCCCGCCGACGCGGCCGGCCTCGCGGAGGCCGCCGC
CCTCCTGCGGGCGGGCCGTCTCGTCGCCTTCCCCACCGAGACCGTCTACGGGCTCGGGGCGGACGCCACCGACCCCGCCG
CGGTGACGGGCATCTTCGCCGCCAAGGCGCGGCCGCGCTTCAACCCGCTGATCTCGCACCTGCCCGACGCGGTGGCGGCC
CTGGCGGAGGGGGTCTTCGACGCGCCGGCGCGCCGCCTCGCGGAGGCCTTCTGGCCCGGCCCCCTGACCCTGGTGGTCCC
GGCGCACACGGGCACGCGGGTCTGCGATCTCGTCCGCGCCGGCCTGCCGAGCCTCGCGCTACGGGTCCCGGCGCACCCGC
TCGCGCGGGACCTCCTGGCGGAGGTCGGGCGGCCGGTCGCGGCGCCCTCGGCCAACTGGTCAGGGCGGGTGAGCCCGACC
CGGGCCGCCCACGTCCTCGACGATCTCGCCGGCCGGATCTCCGCGGTGCTCGACGGCGGTGACACGCCGGTCGGCGTCGA
ATCGACGGTGGTGGCCTGCCTCGGCGGCCCGCCGCGGCTGCTGCGGCCCGGCGGGATCACCCGGGCGGCGCTCCGCGACG
TGCTCGGTCTCGATCCGGCGGCGCCCGAGGCGGCGGATGCCGACCGGCCGGCGGGCCCGGGCATGCTCGCCTCGCACTAC
GCGCCGCGGGCGCGGGTCCGCCTCGACGCGGTGCGGGTCGAGCCCGGCGAGGCGGCCCTGCTGTTCGGGCCCCGCCCCCC
GGCCGGTCACGAGACCGCGCGGGCCAGTCTCAACCTGAGCCCGGCGGGCGATCCCGCGGAGGCCGCTGCCCGGCTGTTCG
GCGCCCTGCGCGACCTCGACGCCTCGGGGGCCGAGACCATCGCGGTGGCGCCGATCCCCGAGGACGGGCTCGGCGAGGCG
ATCCGGGATCGCCTCGCCCGGGCGGCGGCGCCCCGCTGA

Upstream 100 bases:

>100_bases
TCCGGGGCGGGTTTGACCGCGCCCGCGCACCGGCGCTAGGGCGGGGCGAGGATAGGCGCGCGGGGCTCGCGCGGCCATGA
CCTCGGAGACGGCTTCCCGC

Downstream 100 bases:

>100_bases
CGGCGGAGAAATTTTCGCCGGCAGCGGAACAGAGTTCGGCCTGACCCGTTTACTGATCACGAAGGCCTTCTCAGCCCCCA
ATGGCCTTTTTCCTTTCAGG

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MNDPGSTVPSATRRLPADAAGLAEAAALLRAGRLVAFPTETVYGLGADATDPAAVTGIFAAKARPRFNPLISHLPDAVAA
LAEGVFDAPARRLAEAFWPGPLTLVVPAHTGTRVCDLVRAGLPSLALRVPAHPLARDLLAEVGRPVAAPSANWSGRVSPT
RAAHVLDDLAGRISAVLDGGDTPVGVESTVVACLGGPPRLLRPGGITRAALRDVLGLDPAAPEAADADRPAGPGMLASHY
APRARVRLDAVRVEPGEAALLFGPRPPAGHETARASLNLSPAGDPAEAAARLFGALRDLDASGAETIAVAPIPEDGLGEA
IRDRLARAAAPR

Sequences:

>Translated_332_residues
MNDPGSTVPSATRRLPADAAGLAEAAALLRAGRLVAFPTETVYGLGADATDPAAVTGIFAAKARPRFNPLISHLPDAVAA
LAEGVFDAPARRLAEAFWPGPLTLVVPAHTGTRVCDLVRAGLPSLALRVPAHPLARDLLAEVGRPVAAPSANWSGRVSPT
RAAHVLDDLAGRISAVLDGGDTPVGVESTVVACLGGPPRLLRPGGITRAALRDVLGLDPAAPEAADADRPAGPGMLASHY
APRARVRLDAVRVEPGEAALLFGPRPPAGHETARASLNLSPAGDPAEAAARLFGALRDLDASGAETIAVAPIPEDGLGEA
IRDRLARAAAPR
>Mature_332_residues
MNDPGSTVPSATRRLPADAAGLAEAAALLRAGRLVAFPTETVYGLGADATDPAAVTGIFAAKARPRFNPLISHLPDAVAA
LAEGVFDAPARRLAEAFWPGPLTLVVPAHTGTRVCDLVRAGLPSLALRVPAHPLARDLLAEVGRPVAAPSANWSGRVSPT
RAAHVLDDLAGRISAVLDGGDTPVGVESTVVACLGGPPRLLRPGGITRAALRDVLGLDPAAPEAADADRPAGPGMLASHY
APRARVRLDAVRVEPGEAALLFGPRPPAGHETARASLNLSPAGDPAEAAARLFGALRDLDASGAETIAVAPIPEDGLGEA
IRDRLARAAAPR

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=137, Percent_Identity=32.8467153284672, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321269, Length=377, Percent_Identity=35.8090185676393, Blast_Score=172, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 33761; Mature: 33761

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDPGSTVPSATRRLPADAAGLAEAAALLRAGRLVAFPTETVYGLGADATDPAAVTGIFA
CCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCEEEECCHHHEECCCCCCCCHHHHHHHH
AKARPRFNPLISHLPDAVAALAEGVFDAPARRLAEAFWPGPLTLVVPAHTGTRVCDLVRA
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHC
GLPSLALRVPAHPLARDLLAEVGRPVAAPSANWSGRVSPTRAAHVLDDLAGRISAVLDGG
CCCHHEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
DTPVGVESTVVACLGGPPRLLRPGGITRAALRDVLGLDPAAPEAADADRPAGPGMLASHY
CCCCCHHHHEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHC
APRARVRLDAVRVEPGEAALLFGPRPPAGHETARASLNLSPAGDPAEAAARLFGALRDLD
CCCCEEEEEEEEECCCCEEEEECCCCCCCCCHHHEEEECCCCCCHHHHHHHHHHHHHHCC
ASGAETIAVAPIPEDGLGEAIRDRLARAAAPR
CCCCCEEEEECCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNDPGSTVPSATRRLPADAAGLAEAAALLRAGRLVAFPTETVYGLGADATDPAAVTGIFA
CCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCEEEECCHHHEECCCCCCCCHHHHHHHH
AKARPRFNPLISHLPDAVAALAEGVFDAPARRLAEAFWPGPLTLVVPAHTGTRVCDLVRA
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHC
GLPSLALRVPAHPLARDLLAEVGRPVAAPSANWSGRVSPTRAAHVLDDLAGRISAVLDGG
CCCHHEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
DTPVGVESTVVACLGGPPRLLRPGGITRAALRDVLGLDPAAPEAADADRPAGPGMLASHY
CCCCCHHHHEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHC
APRARVRLDAVRVEPGEAALLFGPRPPAGHETARASLNLSPAGDPAEAAARLFGALRDLD
CCCCEEEEEEEEECCCCEEEEECCCCCCCCCHHHEEEECCCCCCHHHHHHHHHHHHHHCC
ASGAETIAVAPIPEDGLGEAIRDRLARAAAPR
CCCCCEEEEECCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]