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The map label for this gene is feaR [H]

Identifier: 170750205

GI number: 170750205

Start: 4048659

End: 4049636

Strand: Reverse

Name: feaR [H]

Synonym: Mrad2831_3807

Alternate gene names: 170750205

Gene position: 4049636-4048659 (Counterclockwise)

Preceding gene: 170750212

Following gene: 170750203

Centisome position: 66.63

GC content: 71.06

Gene sequence:

>978_bases
ATGCAGACTGTGTTCTCGACGGAAGGGCTCCACCCGAGGAACGGGTTCAGGCTGTGGCGGGACCTCCTGGGGGAGCGGCT
CGTGCCGATCGAGGTCGAGCGCCTCGACGACGGACCGTTCCGGGGCAAGCTCGACATCGCCGAGATCGGCGCGCTGCACG
TCTCCCGCCTGACGCAGAGCGCGCTGAAGTGCGAGACGACGCCCAGCGCGGCCCGGCGCCACGACAGGGCCGGGATGGTC
GTGGTGCTGTTCAAGCTCGCGGGCCTGTCGACGAGCGTTCAGGACGGCCGGGAGGCGGTGCAGCGGCCCGGCGACATGCT
GGTGCTCGACCACCGCCCCTCCGTACTGACGACCCACAGGGACAGCCAAGCCCTGTTCCTGGAGCTGCCACGGGAGCGCC
TGGAGGGCGCGCTCGGCTCGACGCGGCTCTACACTGGCCTGTCGGTCGGGGCGGAACTCGCCTCGGCCACGCTGGCGACC
CGCTTCATCCAGGAGTTGATCCGGGTGCGTCACCAGCTCACGCCCGACGCCGCCGAGCGCATGTCGGCGATCGGAGTCGA
CCTGATCGTGGCGAGCCTCGCCGAGCGGCTCGCGCAGGACGTGCCCCGGCCCATCCACGGCAGCGTCGTCGTTCAGCGCG
CCAAGGCGTATGTCGAAGCTCATCTGGGCGACCCGGGCCTCGACCCGCCGCAGCTCGCGGCCGTCATGGGCGTCTCGCTG
CGCCGCCTCCAGGAGCTGTTCCACGAGCGCGGCCAGCACATCTCAGACTGGATCTGGGAACGCCGGCTGGCGGCGGCGGC
CAAGCGCCTGGCGGACCCGGCCTGCCTGCAGCTGTCGATCGGGATGCTCGCCTATGGCTGCGGATTCACGAGTCAAGCGC
ACTTCTCCCGCCGGTTCAAGGATTGCCACGGCCTGACGCCGCGCGAGTACAGGGATGCGGCCGTGCTGCGGGCCACCGGC
GCTCCGTCGGTTCGCTGA

Upstream 100 bases:

>100_bases
TCGTTCGATCGTGAGAATGTATAGAAATATACTTAGCGATCGGGTCGAATGACCGCTGCGCGGCCGACCGATATCGCGGC
GGCGACTCCAGACGTTGCCC

Downstream 100 bases:

>100_bases
CCGCGACGGTGGACGGCCTCGGCCGATCCTGCCCCGCCCCGGCGCGCGGGCCGGCCTCGCGACTCCGCCGAAGGCGCCGC
CGCGCGAGCGGGACTTCAGC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MQTVFSTEGLHPRNGFRLWRDLLGERLVPIEVERLDDGPFRGKLDIAEIGALHVSRLTQSALKCETTPSAARRHDRAGMV
VVLFKLAGLSTSVQDGREAVQRPGDMLVLDHRPSVLTTHRDSQALFLELPRERLEGALGSTRLYTGLSVGAELASATLAT
RFIQELIRVRHQLTPDAAERMSAIGVDLIVASLAERLAQDVPRPIHGSVVVQRAKAYVEAHLGDPGLDPPQLAAVMGVSL
RRLQELFHERGQHISDWIWERRLAAAAKRLADPACLQLSIGMLAYGCGFTSQAHFSRRFKDCHGLTPREYRDAAVLRATG
APSVR

Sequences:

>Translated_325_residues
MQTVFSTEGLHPRNGFRLWRDLLGERLVPIEVERLDDGPFRGKLDIAEIGALHVSRLTQSALKCETTPSAARRHDRAGMV
VVLFKLAGLSTSVQDGREAVQRPGDMLVLDHRPSVLTTHRDSQALFLELPRERLEGALGSTRLYTGLSVGAELASATLAT
RFIQELIRVRHQLTPDAAERMSAIGVDLIVASLAERLAQDVPRPIHGSVVVQRAKAYVEAHLGDPGLDPPQLAAVMGVSL
RRLQELFHERGQHISDWIWERRLAAAAKRLADPACLQLSIGMLAYGCGFTSQAHFSRRFKDCHGLTPREYRDAAVLRATG
APSVR
>Mature_325_residues
MQTVFSTEGLHPRNGFRLWRDLLGERLVPIEVERLDDGPFRGKLDIAEIGALHVSRLTQSALKCETTPSAARRHDRAGMV
VVLFKLAGLSTSVQDGREAVQRPGDMLVLDHRPSVLTTHRDSQALFLELPRERLEGALGSTRLYTGLSVGAELASATLAT
RFIQELIRVRHQLTPDAAERMSAIGVDLIVASLAERLAQDVPRPIHGSVVVQRAKAYVEAHLGDPGLDPPQLAAVMGVSL
RRLQELFHERGQHISDWIWERRLAAAAKRLADPACLQLSIGMLAYGCGFTSQAHFSRRFKDCHGLTPREYRDAAVLRATG
APSVR

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=276, Percent_Identity=27.536231884058, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 35831; Mature: 35831

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTVFSTEGLHPRNGFRLWRDLLGERLVPIEVERLDDGPFRGKLDIAEIGALHVSRLTQS
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
ALKCETTPSAARRHDRAGMVVVLFKLAGLSTSVQDGREAVQRPGDMLVLDHRPSVLTTHR
HHHCCCCHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCCEEEECC
DSQALFLELPRERLEGALGSTRLYTGLSVGAELASATLATRFIQELIRVRHQLTPDAAER
CCCHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
MSAIGVDLIVASLAERLAQDVPRPIHGSVVVQRAKAYVEAHLGDPGLDPPQLAAVMGVSL
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
RRLQELFHERGQHISDWIWERRLAAAAKRLADPACLQLSIGMLAYGCGFTSQAHFSRRFK
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
DCHGLTPREYRDAAVLRATGAPSVR
HHCCCCCHHHHCHHHEEECCCCCCC
>Mature Secondary Structure
MQTVFSTEGLHPRNGFRLWRDLLGERLVPIEVERLDDGPFRGKLDIAEIGALHVSRLTQS
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
ALKCETTPSAARRHDRAGMVVVLFKLAGLSTSVQDGREAVQRPGDMLVLDHRPSVLTTHR
HHHCCCCHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCCEEEECC
DSQALFLELPRERLEGALGSTRLYTGLSVGAELASATLATRFIQELIRVRHQLTPDAAER
CCCHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
MSAIGVDLIVASLAERLAQDVPRPIHGSVVVQRAKAYVEAHLGDPGLDPPQLAAVMGVSL
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
RRLQELFHERGQHISDWIWERRLAAAAKRLADPACLQLSIGMLAYGCGFTSQAHFSRRFK
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
DCHGLTPREYRDAAVLRATGAPSVR
HHCCCCCHHHHCHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]