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The map label for this gene is yoaE [H]

Identifier: 170750212

GI number: 170750212

Start: 4059600

End: 4061738

Strand: Reverse

Name: yoaE [H]

Synonym: Mrad2831_3814

Alternate gene names: 170750212

Gene position: 4061738-4059600 (Counterclockwise)

Preceding gene: 170750217

Following gene: 170750205

Centisome position: 66.83

GC content: 68.21

Gene sequence:

>2139_bases
ATGAACGAGATCGTCCAGCCCGAGGCCTACTCGGAGGTCTTCTACGGCGCCTGCCCGCACGATTGCCCCGACACCTGCTC
GATGCTCTTCGAGGTGAAGGGCGGCGAGCTCCTGAGCGTGCGCGGCAACCCGGACCACCCGATGACCCGCGGCGGTCTCT
GCGTGAAGCTGAAGGATTACGAGAAGCGCCACTACCACCCGGACCGTGTGCTCTACCCGATGAAGCGCGTCGGCCCGAAG
GGCTCCAAGCAGTTCGAGCGGATCACCTGGGACGAGGCGCTCGACACGATCGTCGACCGCTGGACGGCGATCATCGACCG
GTACGGGCCGCAGGCCATCGCGCCCTACAGCTACCTCGGCAACCAGGGCCTCGTGCACGGTCTGAACGGCGGCGACGCCT
TCTTCAACCGCCTGGGCGCCACCGTGACCGAGCGGACGTTCTGCGGCGAGGGCTCGTGCACGGCCTGGCTCCTCACCGTC
GGGCCGACGGCCGGCCTCGATCCCGAGAGCTACATCCACTCCAAGTACATCGTGATCTGGGCCTGCAACTCGGTCAGCAC
CAATCTGCACCACTGGGCGATCGTGAAGGACGCCCAGAAGAAGGGCGCGAAGGTCGTCGTCATCGACGCCTACGCCTCGC
GCACCGCGAAGGCCGCGGACTGGCACATCGCGCCGAGGCCGGGCACCGACGGCGCGCTCGCCATGGCGCTGATCAACTCC
ATCATCGCGCAGGGCCTCGTCGACCAGGACTACGTCGACAACCACACGATCGGCTTCGCCGACCTGAAGGAGCGGGCGGC
CCCGCGCACGCCGGAATGGGCCGCGGAGATCACCGGCGTCCCCGCCGAGGATATCCGCAAGCTCGCCTACGAGATGGCGA
CCGAGCAGCCGGTGGGCATCCGGATGGGCGTGGCGCTGGAGCGGCACTACGGCGGCGGCCAGACCATCCGGGCGGTGACC
TGCATCCCGGCGCTCACCGGCGCGTGGCGCCACGTCGGCGGCGGCGTCACCCAGTTCCCGGTCTGGGAGCATCCCTACAA
GTTCGACGTGATGTGCCGGCCCGACCTGATCCCGGAAGGGACCCGGGTCGTCTCGAACCTCCAGATCGGCCGGGCGCTGA
CCGGCGAGCTGAAGCTCGACCCGCCGATCATGTCGATGATGTGCTGGAACTCGAACCCGGTCACGCAGGCGCCCGAGACC
GACAAGATCGTCGAGGGCCTGATGCGCGAGGACCTGTTCATGGTCTCGGCCGAGCACTTCATCTCCGACACGGCCGCCTA
CGCCGACATCCTCCTGCCGGCCGCGATGGGCGCCGAGATGGAGGACATGATCCTGTCCTGGGGCCACCTCTACCTGACCT
ACAACACCAAGTGCGCGGAGGCGCCCGGCGAGGCGATCCCCAACAACGAGATCTTCCGCCGCCTCGCCGCCCGGCTCGGC
TTCGAGGAGGAGAACTTTAAGTGGACCGACGCGGAGTGCCTGGAGCACTACGTCGACTGGTCGTCGCCGGCCTGCGCGGG
CATCGACCTCCAGTACATGCGCGCGCACGGTTTCGCCCGGCTCAAGGTCGGCACGCCGGACGACCGCGCTCCGCACCGCG
ACGGCAACTTCCCGACCGATACCGGCAAGTGCATGCTCAAGATCGAGGGCGCCACGAACTTCGTCGCGCCGCCGTTCCGG
CAGATGTACGAGGGCTTCCAGCCGGGCGAGCCCCTCGACCCGCTGCCCGATTACGTCGGCGCGCGGGAATCGCACGCGAA
CGATCCCGAGCTGGCCAAGCGCTACCCGCTCAACATCGTCTCGCCCAAGAGCCACTACTTCCTGAATTCCTGCTACGCCA
ACATGGAGGACAAGCAGAAGGGTCAGGGCGAGCAGTTCGTGATGATCAGCCCGGCCGACGCGTTGGCCCGCGGCATCGTC
GACGGCGACCGCGTCCAGGTCGCCAACGCCCGCGGCGCCTTCAAGGGCGTCGCGCGCGTGACCGACGACGTCACGCACGG
CGTCGTGGTGGCGACGCTGGGCTACTGGCGCCAGCTCAACGAGGGGACGGTGAACAGCATCTCGTCGGCGGCCTTCACCG
ACATGGGCCACGCGCCGTCGTTCTCCGACAACCTCGTCGAGGTCTCGCGGGCGAACTGA

Upstream 100 bases:

>100_bases
TCGAATTAGAACTTTTCTTCCTCTCGTTGTACGCTTCTCCCGCCGGGAGCCGGGACGCCTGAACAATAACGGGACGCCTG
CGGCCGATGAGGGAGAGAGC

Downstream 100 bases:

>100_bases
TCGGCGCGGCGCGGCGACCCGCTCCCGGTCGCCGCGCTCGCACGGTCGCCCGGTCAGCCGGCGGCGCTGTCGGCGCTCCG
CCGCCGGCGGGGCCGCGCCG

Product: molybdopterin oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 712; Mature: 712

Protein sequence:

>712_residues
MNEIVQPEAYSEVFYGACPHDCPDTCSMLFEVKGGELLSVRGNPDHPMTRGGLCVKLKDYEKRHYHPDRVLYPMKRVGPK
GSKQFERITWDEALDTIVDRWTAIIDRYGPQAIAPYSYLGNQGLVHGLNGGDAFFNRLGATVTERTFCGEGSCTAWLLTV
GPTAGLDPESYIHSKYIVIWACNSVSTNLHHWAIVKDAQKKGAKVVVIDAYASRTAKAADWHIAPRPGTDGALAMALINS
IIAQGLVDQDYVDNHTIGFADLKERAAPRTPEWAAEITGVPAEDIRKLAYEMATEQPVGIRMGVALERHYGGGQTIRAVT
CIPALTGAWRHVGGGVTQFPVWEHPYKFDVMCRPDLIPEGTRVVSNLQIGRALTGELKLDPPIMSMMCWNSNPVTQAPET
DKIVEGLMREDLFMVSAEHFISDTAAYADILLPAAMGAEMEDMILSWGHLYLTYNTKCAEAPGEAIPNNEIFRRLAARLG
FEEENFKWTDAECLEHYVDWSSPACAGIDLQYMRAHGFARLKVGTPDDRAPHRDGNFPTDTGKCMLKIEGATNFVAPPFR
QMYEGFQPGEPLDPLPDYVGARESHANDPELAKRYPLNIVSPKSHYFLNSCYANMEDKQKGQGEQFVMISPADALARGIV
DGDRVQVANARGAFKGVARVTDDVTHGVVVATLGYWRQLNEGTVNSISSAAFTDMGHAPSFSDNLVEVSRAN

Sequences:

>Translated_712_residues
MNEIVQPEAYSEVFYGACPHDCPDTCSMLFEVKGGELLSVRGNPDHPMTRGGLCVKLKDYEKRHYHPDRVLYPMKRVGPK
GSKQFERITWDEALDTIVDRWTAIIDRYGPQAIAPYSYLGNQGLVHGLNGGDAFFNRLGATVTERTFCGEGSCTAWLLTV
GPTAGLDPESYIHSKYIVIWACNSVSTNLHHWAIVKDAQKKGAKVVVIDAYASRTAKAADWHIAPRPGTDGALAMALINS
IIAQGLVDQDYVDNHTIGFADLKERAAPRTPEWAAEITGVPAEDIRKLAYEMATEQPVGIRMGVALERHYGGGQTIRAVT
CIPALTGAWRHVGGGVTQFPVWEHPYKFDVMCRPDLIPEGTRVVSNLQIGRALTGELKLDPPIMSMMCWNSNPVTQAPET
DKIVEGLMREDLFMVSAEHFISDTAAYADILLPAAMGAEMEDMILSWGHLYLTYNTKCAEAPGEAIPNNEIFRRLAARLG
FEEENFKWTDAECLEHYVDWSSPACAGIDLQYMRAHGFARLKVGTPDDRAPHRDGNFPTDTGKCMLKIEGATNFVAPPFR
QMYEGFQPGEPLDPLPDYVGARESHANDPELAKRYPLNIVSPKSHYFLNSCYANMEDKQKGQGEQFVMISPADALARGIV
DGDRVQVANARGAFKGVARVTDDVTHGVVVATLGYWRQLNEGTVNSISSAAFTDMGHAPSFSDNLVEVSRAN
>Mature_712_residues
MNEIVQPEAYSEVFYGACPHDCPDTCSMLFEVKGGELLSVRGNPDHPMTRGGLCVKLKDYEKRHYHPDRVLYPMKRVGPK
GSKQFERITWDEALDTIVDRWTAIIDRYGPQAIAPYSYLGNQGLVHGLNGGDAFFNRLGATVTERTFCGEGSCTAWLLTV
GPTAGLDPESYIHSKYIVIWACNSVSTNLHHWAIVKDAQKKGAKVVVIDAYASRTAKAADWHIAPRPGTDGALAMALINS
IIAQGLVDQDYVDNHTIGFADLKERAAPRTPEWAAEITGVPAEDIRKLAYEMATEQPVGIRMGVALERHYGGGQTIRAVT
CIPALTGAWRHVGGGVTQFPVWEHPYKFDVMCRPDLIPEGTRVVSNLQIGRALTGELKLDPPIMSMMCWNSNPVTQAPET
DKIVEGLMREDLFMVSAEHFISDTAAYADILLPAAMGAEMEDMILSWGHLYLTYNTKCAEAPGEAIPNNEIFRRLAARLG
FEEENFKWTDAECLEHYVDWSSPACAGIDLQYMRAHGFARLKVGTPDDRAPHRDGNFPTDTGKCMLKIEGATNFVAPPFR
QMYEGFQPGEPLDPLPDYVGARESHANDPELAKRYPLNIVSPKSHYFLNSCYANMEDKQKGQGEQFVMISPADALARGIV
DGDRVQVANARGAFKGVARVTDDVTHGVVVATLGYWRQLNEGTVNSISSAAFTDMGHAPSFSDNLVEVSRAN

Specific function: Terminal Reductase During Anaerobic Growth On Various Sulfoxide And N-Oxide Compounds (By Similarity). [C]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm Face Of The Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787870, Length=787, Percent_Identity=28.7166454891995, Blast_Score=235, Evalue=6e-63,
Organism=Escherichia coli, GI171474008, Length=776, Percent_Identity=28.3505154639175, Blast_Score=232, Evalue=8e-62,
Organism=Escherichia coli, GI87081797, Length=781, Percent_Identity=27.6568501920615, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI145693196, Length=739, Percent_Identity=23.680649526387, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI3868721, Length=732, Percent_Identity=23.9071038251366, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI87081994, Length=752, Percent_Identity=22.0744680851064, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1787231, Length=490, Percent_Identity=23.8775510204082, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1788534, Length=740, Percent_Identity=21.7567567567568, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1787741, Length=294, Percent_Identity=24.1496598639456, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.8.99.- [C]

Molecular weight: Translated: 78478; Mature: 78478

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00932 MOLYBDOPTERIN_PROK_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEIVQPEAYSEVFYGACPHDCPDTCSMLFEVKGGELLSVRGNPDHPMTRGGLCVKLKDY
CCCCCCCHHHHHHHCCCCCCCCHHHHHHHEEECCCEEEEECCCCCCCCCCCCEEEEEECC
EKRHYHPDRVLYPMKRVGPKGSKQFERITWDEALDTIVDRWTAIIDRYGPQAIAPYSYLG
HHHCCCCCHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHC
NQGLVHGLNGGDAFFNRLGATVTERTFCGEGSCTAWLLTVGPTAGLDPESYIHSKYIVIW
CCCCEEECCCHHHHHHHHCCHHHHHEECCCCCCEEEEEEECCCCCCCHHHHHCCCEEEEE
ACNSVSTNLHHWAIVKDAQKKGAKVVVIDAYASRTAKAADWHIAPRPGTDGALAMALINS
EECCCCCCCEEEEEEEHHHHCCCEEEEEECCCCCCCCCCCCEECCCCCCCHHHHHHHHHH
IIAQGLVDQDYVDNHTIGFADLKERAAPRTPEWAAEITGVPAEDIRKLAYEMATEQPVGI
HHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCE
RMGVALERHYGGGQTIRAVTCIPALTGAWRHVGGGVTQFPVWEHPYKFDVMCRPDLIPEG
EEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCC
TRVVSNLQIGRALTGELKLDPPIMSMMCWNSNPVTQAPETDKIVEGLMREDLFMVSAEHF
HHHHHHHHHCCEEECCEEECCHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ISDTAAYADILLPAAMGAEMEDMILSWGHLYLTYNTKCAEAPGEAIPNNEIFRRLAARLG
HHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCC
FEEENFKWTDAECLEHYVDWSSPACAGIDLQYMRAHGFARLKVGTPDDRAPHRDGNFPTD
CCCCCCEECCHHHHHHHHCCCCCCCCCCCHHHHHHCCEEEEEECCCCCCCCCCCCCCCCC
TGKCMLKIEGATNFVAPPFRQMYEGFQPGEPLDPLPDYVGARESHANDPELAKRYPLNIV
CCCEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHCCCEEE
SPKSHYFLNSCYANMEDKQKGQGEQFVMISPADALARGIVDGDRVQVANARGAFKGVARV
CCCHHHHHHHHHCCCCHHHCCCCCEEEEECCHHHHHHHCCCCCEEEEECCCCHHHHHHHH
TDDVTHGVVVATLGYWRQLNEGTVNSISSAAFTDMGHAPSFSDNLVEVSRAN
HHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCC
>Mature Secondary Structure
MNEIVQPEAYSEVFYGACPHDCPDTCSMLFEVKGGELLSVRGNPDHPMTRGGLCVKLKDY
CCCCCCCHHHHHHHCCCCCCCCHHHHHHHEEECCCEEEEECCCCCCCCCCCCEEEEEECC
EKRHYHPDRVLYPMKRVGPKGSKQFERITWDEALDTIVDRWTAIIDRYGPQAIAPYSYLG
HHHCCCCCHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHC
NQGLVHGLNGGDAFFNRLGATVTERTFCGEGSCTAWLLTVGPTAGLDPESYIHSKYIVIW
CCCCEEECCCHHHHHHHHCCHHHHHEECCCCCCEEEEEEECCCCCCCHHHHHCCCEEEEE
ACNSVSTNLHHWAIVKDAQKKGAKVVVIDAYASRTAKAADWHIAPRPGTDGALAMALINS
EECCCCCCCEEEEEEEHHHHCCCEEEEEECCCCCCCCCCCCEECCCCCCCHHHHHHHHHH
IIAQGLVDQDYVDNHTIGFADLKERAAPRTPEWAAEITGVPAEDIRKLAYEMATEQPVGI
HHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCE
RMGVALERHYGGGQTIRAVTCIPALTGAWRHVGGGVTQFPVWEHPYKFDVMCRPDLIPEG
EEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCC
TRVVSNLQIGRALTGELKLDPPIMSMMCWNSNPVTQAPETDKIVEGLMREDLFMVSAEHF
HHHHHHHHHCCEEECCEEECCHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ISDTAAYADILLPAAMGAEMEDMILSWGHLYLTYNTKCAEAPGEAIPNNEIFRRLAARLG
HHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCC
FEEENFKWTDAECLEHYVDWSSPACAGIDLQYMRAHGFARLKVGTPDDRAPHRDGNFPTD
CCCCCCEECCHHHHHHHHCCCCCCCCCCCHHHHHHCCEEEEEECCCCCCCCCCCCCCCCC
TGKCMLKIEGATNFVAPPFRQMYEGFQPGEPLDPLPDYVGARESHANDPELAKRYPLNIV
CCCEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHCCCEEE
SPKSHYFLNSCYANMEDKQKGQGEQFVMISPADALARGIVDGDRVQVANARGAFKGVARV
CCCHHHHHHHHHCCCCHHHCCCCCEEEEECCHHHHHHHCCCCCEEEEECCCCHHHHHHHH
TDDVTHGVVVATLGYWRQLNEGTVNSISSAAFTDMGHAPSFSDNLVEVSRAN
HHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: May Bind 4Fe-4S Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]