Click here to switch to the map view.

The map label for this gene is hit [H]

Identifier: 170750151

GI number: 170750151

Start: 3995578

End: 3996015

Strand: Reverse

Name: hit [H]

Synonym: Mrad2831_3753

Alternate gene names: 170750151

Gene position: 3996015-3995578 (Counterclockwise)

Preceding gene: 170750153

Following gene: 170750147

Centisome position: 65.75

GC content: 71.69

Gene sequence:

>438_bases
ATGGCCGACGCCCGCTACGATCCCGACAACATCTTCGCCAAGATCCTGCACGGCGAGATCCCCTGCCACCGCGTCTACGA
GGACGCCCACACCCTGGCCTTCATGGACGTGATGCCCCAGGGCGAGGGCCACACGCTGGTGATCCCGAAGGCGCCGGCCC
GCGGCCTGCTCGACGCCAACCCGGACTCGCTCGCCGCGCTGATGGCGAGCGTCCAGAAGGTCGCCCGCGCCGTGAAGGCC
GCCTTCCGGGCCGAGGGTCTGACCCTGTTCCAGTTCAACGAGCCGGCCGGCGGCCAGACCGTGTTCCACCTGCACGTCCA
CGTCATCCCGCGGCGCGAGGGCGTGCCGCTGAAGCGCCACGAGGGCGGGATGGCCGACAACGCGGTCCTCGCCGAGCACG
CCGCGCGCATCCGCGCGGCGCTCGAGTCTCAGGCCTGA

Upstream 100 bases:

>100_bases
CCGCGGCGATGCAAGCGTCGCGGCGGGTCGGTTGTTCCCGTGTGGACGCGGGCGGGTACCCCGTGCAACCTGCGGCCGCT
CAAGGAGTCCCGGAGGCAGC

Downstream 100 bases:

>100_bases
CGCTCAGGCCCGGGACTCAGGCCGCGCTCGCCGAATCGCCCGACTGGGCCATGCTGGCGAGCAGCCGGCGCAGGGCGGCG
TTCTCGGTCTCGAGCTCGCT

Product: histidine triad (HIT) protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MADARYDPDNIFAKILHGEIPCHRVYEDAHTLAFMDVMPQGEGHTLVIPKAPARGLLDANPDSLAALMASVQKVARAVKA
AFRAEGLTLFQFNEPAGGQTVFHLHVHVIPRREGVPLKRHEGGMADNAVLAEHAARIRAALESQA

Sequences:

>Translated_145_residues
MADARYDPDNIFAKILHGEIPCHRVYEDAHTLAFMDVMPQGEGHTLVIPKAPARGLLDANPDSLAALMASVQKVARAVKA
AFRAEGLTLFQFNEPAGGQTVFHLHVHVIPRREGVPLKRHEGGMADNAVLAEHAARIRAALESQA
>Mature_144_residues
ADARYDPDNIFAKILHGEIPCHRVYEDAHTLAFMDVMPQGEGHTLVIPKAPARGLLDANPDSLAALMASVQKVARAVKAA
FRAEGLTLFQFNEPAGGQTVFHLHVHVIPRREGVPLKRHEGGMADNAVLAEHAARIRAALESQA

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI261278358, Length=84, Percent_Identity=38.0952380952381, Blast_Score=63, Evalue=8e-11,
Organism=Homo sapiens, GI4503719, Length=84, Percent_Identity=38.0952380952381, Blast_Score=63, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17506713, Length=108, Percent_Identity=38.8888888888889, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320078, Length=112, Percent_Identity=34.8214285714286, Blast_Score=69, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28574010, Length=108, Percent_Identity=40.7407407407407, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24581222, Length=108, Percent_Identity=40.7407407407407, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 15731; Mature: 15600

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADARYDPDNIFAKILHGEIPCHRVYEDAHTLAFMDVMPQGEGHTLVIPKAPARGLLDAN
CCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHEEEEEECCCCCCCEEEEECCCCCCCCCCC
PDSLAALMASVQKVARAVKAAFRAEGLTLFQFNEPAGGQTVFHLHVHVIPRREGVPLKRH
HHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEEEEEEECCCCCCCCCC
EGGMADNAVLAEHAARIRAALESQA
CCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADARYDPDNIFAKILHGEIPCHRVYEDAHTLAFMDVMPQGEGHTLVIPKAPARGLLDAN
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHEEEEEECCCCCCCEEEEECCCCCCCCCCC
PDSLAALMASVQKVARAVKAAFRAEGLTLFQFNEPAGGQTVFHLHVHVIPRREGVPLKRH
HHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEEEEEEECCCCCCCCCC
EGGMADNAVLAEHAARIRAALESQA
CCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]