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The map label for this gene is yncB [H]

Identifier: 170750134

GI number: 170750134

Start: 3976859

End: 3977878

Strand: Direct

Name: yncB [H]

Synonym: Mrad2831_3736

Alternate gene names: 170750134

Gene position: 3976859-3977878 (Clockwise)

Preceding gene: 170750131

Following gene: 170750135

Centisome position: 65.43

GC content: 71.47

Gene sequence:

>1020_bases
ATGACCACCGCCATGAACCGCCGCATCGTCCTGGCCTCGCGCCCGCACGGCGAGCCGCGGCCCGAGAATTTCCGCCTGGA
AGAGGTGCCGGTGCCGCAGCCCGGACCCGGCCAGGTCCTGCTGCGCACCCGCTGGCTGTCCCTGGACCCCTACATGCGCG
GCCGGATGAGCGACGCGAAATCCTACGCGGCGCCGGTCGAGATCGGCGCGCCGATCACCGCCGAAACCGTCGGTGAGGTG
GTCGCCTCCAACCACCCGGATCACGCCGTGGGCGACCTGCTGACGGCCTTCGCGGGCTGGCAGGAGTACTGCGTCACCGA
CGCCAAGGGGTCGCGCAAGGTCGACCCCGCCGCCGCTCCGCCCTCGACGGCGCTCGGCGTGCTCGGGATGCCGGGCATGA
CCGCCTATACCGGCCTCCTCAACATCGGCCGGCCGAAGTTCGGCGAGACCGTCGTGGTGGCGGCCGCCGCCGGCCCCGTC
GGCTCCCTGGTCGGCCAGATCGCCAAGATCCACGGCGCCCGCGCCGTCGGGATCGCGGGCGGTCCCGAGAAGTGCCGCTA
CCTCACGGAGGAGCTCGGCTTCGACGCGGCCATCGACCACCGCGGATCCGACCTGCCGGGCACGCTCGCCGCAGCCTGCC
CGAAGGGCATCGACGTGTACTTCGAGAATGTCGGCGGCGCGGTCTTCGCGGCCGTTCTGCCGCTGCTGAATCCGTTCGCG
CGGATCCCGGTCTGCGGCCTCGTCTCCGCCTACAACGCCACCGAGGTGCCCCCCGGCCCGGACCGCCTGCCCGGCCTGAT
GCGCTCGGTCCTGACCAACCGGCTGCACATCCAGGGCTTCATCGTCTGGGACTTCGCCGAGCAGGCGGAGACGTTCCGCA
AGGAGGTCGCAGGGTGGATCCAGGACGGGCGCGTCCGCTACCGCGAGGACGTGGTCGAGGGGCTGGAGAACGCTCCGGAG
GCGTTCATCGGCCTGTTGAAAGGCCGGAATTTCGGCAAGCTCGTGGTCCGGGTGTCCTGA

Upstream 100 bases:

>100_bases
CGGGACAACGCGCGACTCGTCCGCGCGATCACGGCGGAGCCTTTGCCTCCCGGGCCCGGCGCCCCAGATCGGAGCGGGAG
CCAGTTTCCGGGAGTCCGCC

Downstream 100 bases:

>100_bases
CAGAGCCTTGCCGCCCGAATGGAACAGAGATAGAACAAGAAGATCCGTCGGCGCTGCGGAAAGCGGGCACAAGCCTGACC
CGCCGGTTGCCGCTCCGGAA

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MTTAMNRRIVLASRPHGEPRPENFRLEEVPVPQPGPGQVLLRTRWLSLDPYMRGRMSDAKSYAAPVEIGAPITAETVGEV
VASNHPDHAVGDLLTAFAGWQEYCVTDAKGSRKVDPAAAPPSTALGVLGMPGMTAYTGLLNIGRPKFGETVVVAAAAGPV
GSLVGQIAKIHGARAVGIAGGPEKCRYLTEELGFDAAIDHRGSDLPGTLAAACPKGIDVYFENVGGAVFAAVLPLLNPFA
RIPVCGLVSAYNATEVPPGPDRLPGLMRSVLTNRLHIQGFIVWDFAEQAETFRKEVAGWIQDGRVRYREDVVEGLENAPE
AFIGLLKGRNFGKLVVRVS

Sequences:

>Translated_339_residues
MTTAMNRRIVLASRPHGEPRPENFRLEEVPVPQPGPGQVLLRTRWLSLDPYMRGRMSDAKSYAAPVEIGAPITAETVGEV
VASNHPDHAVGDLLTAFAGWQEYCVTDAKGSRKVDPAAAPPSTALGVLGMPGMTAYTGLLNIGRPKFGETVVVAAAAGPV
GSLVGQIAKIHGARAVGIAGGPEKCRYLTEELGFDAAIDHRGSDLPGTLAAACPKGIDVYFENVGGAVFAAVLPLLNPFA
RIPVCGLVSAYNATEVPPGPDRLPGLMRSVLTNRLHIQGFIVWDFAEQAETFRKEVAGWIQDGRVRYREDVVEGLENAPE
AFIGLLKGRNFGKLVVRVS
>Mature_338_residues
TTAMNRRIVLASRPHGEPRPENFRLEEVPVPQPGPGQVLLRTRWLSLDPYMRGRMSDAKSYAAPVEIGAPITAETVGEVV
ASNHPDHAVGDLLTAFAGWQEYCVTDAKGSRKVDPAAAPPSTALGVLGMPGMTAYTGLLNIGRPKFGETVVVAAAAGPVG
SLVGQIAKIHGARAVGIAGGPEKCRYLTEELGFDAAIDHRGSDLPGTLAAACPKGIDVYFENVGGAVFAAVLPLLNPFAR
IPVCGLVSAYNATEVPPGPDRLPGLMRSVLTNRLHIQGFIVWDFAEQAETFRKEVAGWIQDGRVRYREDVVEGLENAPEA
FIGLLKGRNFGKLVVRVS

Specific function: Unknown

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADP-dependent oxidoreductase L4BD family [H]

Homologues:

Organism=Homo sapiens, GI226246682, Length=344, Percent_Identity=37.7906976744186, Blast_Score=225, Evalue=6e-59,
Organism=Homo sapiens, GI226246680, Length=344, Percent_Identity=37.7906976744186, Blast_Score=225, Evalue=6e-59,
Organism=Homo sapiens, GI22748929, Length=344, Percent_Identity=37.7906976744186, Blast_Score=225, Evalue=6e-59,
Organism=Homo sapiens, GI226059159, Length=340, Percent_Identity=37.6470588235294, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI226059133, Length=340, Percent_Identity=37.6470588235294, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI226056130, Length=313, Percent_Identity=35.7827476038339, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI28557745, Length=359, Percent_Identity=28.6908077994429, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI226510941, Length=335, Percent_Identity=61.1940298507463, Blast_Score=426, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI133901710, Length=356, Percent_Identity=32.0224719101124, Blast_Score=178, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI133901712, Length=356, Percent_Identity=31.7415730337079, Blast_Score=178, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6323504, Length=334, Percent_Identity=28.1437125748503, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36080; Mature: 35949

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAMNRRIVLASRPHGEPRPENFRLEEVPVPQPGPGQVLLRTRWLSLDPYMRGRMSDAK
CCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEEEEECCCCHHHHCCHHHHH
SYAAPVEIGAPITAETVGEVVASNHPDHAVGDLLTAFAGWQEYCVTDAKGSRKVDPAAAP
HHCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHEECCCCCCCCCCCCCC
PSTALGVLGMPGMTAYTGLLNIGRPKFGETVVVAAAAGPVGSLVGQIAKIHGARAVGIAG
CCHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCC
GPEKCRYLTEELGFDAAIDHRGSDLPGTLAAACPKGIDVYFENVGGAVFAAVLPLLNPFA
CHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHCCCCCEEEEHHCCHHHHHHHHHHHCHHH
RIPVCGLVSAYNATEVPPGPDRLPGLMRSVLTNRLHIQGFIVWDFAEQAETFRKEVAGWI
HCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEEECHHHHHHHHHHHHHHHH
QDGRVRYREDVVEGLENAPEAFIGLLKGRNFGKLVVRVS
HCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEEC
>Mature Secondary Structure 
TTAMNRRIVLASRPHGEPRPENFRLEEVPVPQPGPGQVLLRTRWLSLDPYMRGRMSDAK
CCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEEEEECCCCHHHHCCHHHHH
SYAAPVEIGAPITAETVGEVVASNHPDHAVGDLLTAFAGWQEYCVTDAKGSRKVDPAAAP
HHCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHEECCCCCCCCCCCCCC
PSTALGVLGMPGMTAYTGLLNIGRPKFGETVVVAAAAGPVGSLVGQIAKIHGARAVGIAG
CCHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCC
GPEKCRYLTEELGFDAAIDHRGSDLPGTLAAACPKGIDVYFENVGGAVFAAVLPLLNPFA
CHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHCCCCCEEEEHHCCHHHHHHHHHHHCHHH
RIPVCGLVSAYNATEVPPGPDRLPGLMRSVLTNRLHIQGFIVWDFAEQAETFRKEVAGWI
HCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEEECHHHHHHHHHHHHHHHH
QDGRVRYREDVVEGLENAPEAFIGLLKGRNFGKLVVRVS
HCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]