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The map label for this gene is pheA [H]

Identifier: 170750049

GI number: 170750049

Start: 3883987

End: 3884844

Strand: Direct

Name: pheA [H]

Synonym: Mrad2831_3650

Alternate gene names: 170750049

Gene position: 3883987-3884844 (Clockwise)

Preceding gene: 170750048

Following gene: 170750051

Centisome position: 63.9

GC content: 71.45

Gene sequence:

>858_bases
ATGACCGACCGCACCATCGCCTACCAGGGTGAGCCCGGGGCCAACTCGCACATCATCTGCGCGGAGGCCTACCCGGACTG
GACACCCCTCCCCTGCCCGACCTTCGAGGACGCCTTCGCGGCGGTGACGGAGGGGCGCGCCCAGCGGGCGATGATCCCGA
TCGAGAACTCGATCGCGGGCCGGGTCGCCGACATCCACCACCTGATCCCGATCTCGCCGCTGCACATCGTGGCCGAGCAC
TTCCTGCCGATCCACTTCCAGCTGATGGTCCTGCCGGGCACGAAGCGCGAGTCGCTGAGGAGCGTCCACAGCCACGTCCA
CGCGCTGGGCCAGTGCCGCCGGATCATCCGGCGGATGGGCCTGAAGGCCGTGGTCGCCGGCGACACCGCCGGGGCGGCCC
GCGAGATCGCCGAGATCGGCGACCCGAGCCGGGCGGCCCTGGCGCCCGCGCTCGCCGCCGAGGTCTACGGCCTCGACATC
CTGGAGCGCGACGTCGAGGACGAGGCGCACAACACCACCCGGTTCGTGGTCTTCTCCCCCGAGCCCGTGCCGGTCGCCCA
GGGCACCGAGCCCTGCGTGACGAGCTTCGTGTTCCGCGTCCGCAACATCCCGGCCGCCCTCTACAAGGCGCTCGGCGGCT
TCGCGACCAACGGCGTCAACATGTCGAAGCTCGAGAGCTACATGGTCGACGGCGAGTTCACCGCCACGCAGTTCTACGCC
GAGGTCGACGGCCACCCGGAGGATCCGGGCCTCAGCCGCGCGCTCGACGAGCTCGGCTTCTTCTCGCGCGAGCTGCGGGT
GATCGGCACCTACCCGGCCCACCCGTTCCGGGAGGCGGCGCGGCCGGCAGCGGAGTGA

Upstream 100 bases:

>100_bases
CCTGCCGCTCGGCGTCGACACTCCCGCCGACCTGGAACGGGCCCGCGCCCTGCTGCAGGGCCGGCGCCTGAACTGACACG
CCGAACGAATCCGCGCCGCC

Downstream 100 bases:

>100_bases
GCCCTCACTCCCGCCGGAGCACCCGGTCGGCCGCCAGATCCGACCAGAAGCCCGGCCGGAAGTCGCGCTTGAGCGCCTCG
GGATCGTAGACGGTCTCGAC

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MTDRTIAYQGEPGANSHIICAEAYPDWTPLPCPTFEDAFAAVTEGRAQRAMIPIENSIAGRVADIHHLIPISPLHIVAEH
FLPIHFQLMVLPGTKRESLRSVHSHVHALGQCRRIIRRMGLKAVVAGDTAGAAREIAEIGDPSRAALAPALAAEVYGLDI
LERDVEDEAHNTTRFVVFSPEPVPVAQGTEPCVTSFVFRVRNIPAALYKALGGFATNGVNMSKLESYMVDGEFTATQFYA
EVDGHPEDPGLSRALDELGFFSRELRVIGTYPAHPFREAARPAAE

Sequences:

>Translated_285_residues
MTDRTIAYQGEPGANSHIICAEAYPDWTPLPCPTFEDAFAAVTEGRAQRAMIPIENSIAGRVADIHHLIPISPLHIVAEH
FLPIHFQLMVLPGTKRESLRSVHSHVHALGQCRRIIRRMGLKAVVAGDTAGAAREIAEIGDPSRAALAPALAAEVYGLDI
LERDVEDEAHNTTRFVVFSPEPVPVAQGTEPCVTSFVFRVRNIPAALYKALGGFATNGVNMSKLESYMVDGEFTATQFYA
EVDGHPEDPGLSRALDELGFFSRELRVIGTYPAHPFREAARPAAE
>Mature_284_residues
TDRTIAYQGEPGANSHIICAEAYPDWTPLPCPTFEDAFAAVTEGRAQRAMIPIENSIAGRVADIHHLIPISPLHIVAEHF
LPIHFQLMVLPGTKRESLRSVHSHVHALGQCRRIIRRMGLKAVVAGDTAGAAREIAEIGDPSRAALAPALAAEVYGLDIL
ERDVEDEAHNTTRFVVFSPEPVPVAQGTEPCVTSFVFRVRNIPAALYKALGGFATNGVNMSKLESYMVDGEFTATQFYAE
VDGHPEDPGLSRALDELGFFSRELRVIGTYPAHPFREAARPAAE

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=273, Percent_Identity=30.03663003663, Blast_Score=130, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 31045; Mature: 30913

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRTIAYQGEPGANSHIICAEAYPDWTPLPCPTFEDAFAAVTEGRAQRAMIPIENSIAG
CCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCHHEEECCCCCCHHH
RVADIHHLIPISPLHIVAEHFLPIHFQLMVLPGTKRESLRSVHSHVHALGQCRRIIRRMG
HHHHHHHHCCCCHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LKAVVAGDTAGAAREIAEIGDPSRAALAPALAAEVYGLDILERDVEDEAHNTTRFVVFSP
CEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
EPVPVAQGTEPCVTSFVFRVRNIPAALYKALGGFATNGVNMSKLESYMVDGEFTATQFYA
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCHHCCCCCHHHHHHHHCCCCEEHHEEEE
EVDGHPEDPGLSRALDELGFFSRELRVIGTYPAHPFREAARPAAE
ECCCCCCCCCHHHHHHHHHHHHHCEEEEECCCCCHHHHHCCCCCC
>Mature Secondary Structure 
TDRTIAYQGEPGANSHIICAEAYPDWTPLPCPTFEDAFAAVTEGRAQRAMIPIENSIAG
CCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCHHEEECCCCCCHHH
RVADIHHLIPISPLHIVAEHFLPIHFQLMVLPGTKRESLRSVHSHVHALGQCRRIIRRMG
HHHHHHHHCCCCHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LKAVVAGDTAGAAREIAEIGDPSRAALAPALAAEVYGLDILERDVEDEAHNTTRFVVFSP
CEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
EPVPVAQGTEPCVTSFVFRVRNIPAALYKALGGFATNGVNMSKLESYMVDGEFTATQFYA
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCHHCCCCCHHHHHHHHCCCCEEHHEEEE
EVDGHPEDPGLSRALDELGFFSRELRVIGTYPAHPFREAARPAAE
ECCCCCCCCCHHHHHHHHHHHHHCEEEEECCCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1512561; 1444388 [H]