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The map label for this gene is moxX [H]

Identifier: 170749794

GI number: 170749794

Start: 3601800

End: 3602474

Strand: Reverse

Name: moxX [H]

Synonym: Mrad2831_3393

Alternate gene names: 170749794

Gene position: 3602474-3601800 (Counterclockwise)

Preceding gene: 170749795

Following gene: 170749793

Centisome position: 59.27

GC content: 71.41

Gene sequence:

>675_bases
ATGAACGCCATCGCATCCCAGATCGACGCCGCCGCCACCCGCCTGCCGGTCCTCGTCATCGATGATCACCCCATCGTCCT
GCAGGGCTGTCGACGGGTGCTGGAGGATTCCGGCGTCGAGACCATCGCGGAGGCGACGACCGTCGTCGGCGGCTACCGGA
TCTTCCACCGGCTCCGCCCGCCGGTCGTGATCTGCGACCTGACCTTCCAGGGCAGCGGCATGGCCGGGCTCGGCCTGATC
CGGCGCATCCGGGCGGTCGCACCCGAGACGCGCATCCTGGTCTTCAGCATGCACAACGACCCGGTGATCGTCGCCCGCGC
CCTCGAGGCGGGGGCCCTCGGCTACGTCCTCAAGGACCACGCCTCGGCCGAGCTGTTCGAGGCCTTCGCCAAGGTCCGCG
TCGGCGAGGTCTACCTCGACCGGCGCCTGGCGACCGAGGTGGCGATGCTGCGCGCCGATGCCCGCCGCGCGCCGGAATCG
CAGCTGACCCCCCGCGAGCAGCAGATCCTGGCGCGCCTCGCGCAGGGGCGCTCCTACGGGGCCATCGCGGCCGACCTGTC
GGTGAGCTACAAGACCGTGACCAACGCCTGCTCGCAGATGCGCCAGAAGCTCGGCGTGCGCACCCTCGCCGAGCTGATCC
ACGTCGCCGTCACCCACGCGCAGCGGCAGGGCTAG

Upstream 100 bases:

>100_bases
GCACCTTCGCCCTTGACAATGCCGGCCCCGGGGCGATCGTCCGGATCACGATCCCCGTTCCGCCTGACCGGGGCGACGAG
AACAACACCGCGCCGAGCGC

Downstream 100 bases:

>100_bases
GCCGTGGCGTCCCCCGGACTGGCGGGCGCCCTGGGCGCCTTCTCCCAGGAGGCCTGGGCGCGCAACGCCGCGGCCTACGA
GACCATCCGGTCGATGCCGT

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MNAIASQIDAAATRLPVLVIDDHPIVLQGCRRVLEDSGVETIAEATTVVGGYRIFHRLRPPVVICDLTFQGSGMAGLGLI
RRIRAVAPETRILVFSMHNDPVIVARALEAGALGYVLKDHASAELFEAFAKVRVGEVYLDRRLATEVAMLRADARRAPES
QLTPREQQILARLAQGRSYGAIAADLSVSYKTVTNACSQMRQKLGVRTLAELIHVAVTHAQRQG

Sequences:

>Translated_224_residues
MNAIASQIDAAATRLPVLVIDDHPIVLQGCRRVLEDSGVETIAEATTVVGGYRIFHRLRPPVVICDLTFQGSGMAGLGLI
RRIRAVAPETRILVFSMHNDPVIVARALEAGALGYVLKDHASAELFEAFAKVRVGEVYLDRRLATEVAMLRADARRAPES
QLTPREQQILARLAQGRSYGAIAADLSVSYKTVTNACSQMRQKLGVRTLAELIHVAVTHAQRQG
>Mature_224_residues
MNAIASQIDAAATRLPVLVIDDHPIVLQGCRRVLEDSGVETIAEATTVVGGYRIFHRLRPPVVICDLTFQGSGMAGLGLI
RRIRAVAPETRILVFSMHNDPVIVARALEAGALGYVLKDHASAELFEAFAKVRVGEVYLDRRLATEVAMLRADARRAPES
QLTPREQQILARLAQGRSYGAIAADLSVSYKTVTNACSQMRQKLGVRTLAELIHVAVTHAQRQG

Specific function: Member of the two-component regulatory system moxY/moxX probably involved in the regulation of the methanol dehydrogenase expression [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=29.6650717703349, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788521, Length=201, Percent_Identity=33.8308457711443, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1788546, Length=198, Percent_Identity=29.2929292929293, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1786747, Length=204, Percent_Identity=27.4509803921569, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788712, Length=209, Percent_Identity=25.8373205741627, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790102, Length=201, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787473, Length=182, Percent_Identity=34.6153846153846, Blast_Score=74, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24374; Mature: 24374

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAIASQIDAAATRLPVLVIDDHPIVLQGCRRVLEDSGVETIAEATTVVGGYRIFHRLRP
CCHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
PVVICDLTFQGSGMAGLGLIRRIRAVAPETRILVFSMHNDPVIVARALEAGALGYVLKDH
CEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEHHHCCHHHHHHHHC
ASAELFEAFAKVRVGEVYLDRRLATEVAMLRADARRAPESQLTPREQQILARLAQGRSYG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCC
AIAADLSVSYKTVTNACSQMRQKLGVRTLAELIHVAVTHAQRQG
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNAIASQIDAAATRLPVLVIDDHPIVLQGCRRVLEDSGVETIAEATTVVGGYRIFHRLRP
CCHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
PVVICDLTFQGSGMAGLGLIRRIRAVAPETRILVFSMHNDPVIVARALEAGALGYVLKDH
CEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEHHHCCHHHHHHHHC
ASAELFEAFAKVRVGEVYLDRRLATEVAMLRADARRAPESQLTPREQQILARLAQGRSYG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCC
AIAADLSVSYKTVTNACSQMRQKLGVRTLAELIHVAVTHAQRQG
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8392137 [H]