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The map label for this gene is tenA [H]

Identifier: 170749793

GI number: 170749793

Start: 3601104

End: 3601796

Strand: Reverse

Name: tenA [H]

Synonym: Mrad2831_3392

Alternate gene names: 170749793

Gene position: 3601796-3601104 (Counterclockwise)

Preceding gene: 170749794

Following gene: 170749792

Centisome position: 59.26

GC content: 73.02

Gene sequence:

>693_bases
GTGGCGTCCCCCGGACTGGCGGGCGCCCTGGGCGCCTTCTCCCAGGAGGCCTGGGCGCGCAACGCCGCGGCCTACGAGAC
CATCCGGTCGATGCCGTTCAACGCCGAGCTCGCCGCCGGCACGCTGCCGCAGGACCGGTTCCGGCACTACATCGTGCAGG
ACGCGCACTACCTGATCGGCTTCGGCCGGGCGCTGAGCCTCGCCGCCGCGAAGGCGCCGGATCCGGACACGATCGTGCAG
TTCTCCCGCGCTGCGCAGGAGGCGATCGTCGTCGAGCGCGCCCTCCACGGCGGCTTCTTCCGCGACTATGGCATCGGGCC
GGAGACCTTCGCGGCGACGCCGCTGACGCCGGCCTGCGACCACTACGTCTGCTACCTCGTGGCCACCGCCTACGCCGAGC
CCTACGCGGTGCTCTGCGCGGCCCTGTTGCCCTGCTTCTGGATCTACAAGGCGGTCGGCGACGATATCTTCGCCCGCGCG
GCGCCCGACAACCCGTACCGCGCCTGGATCGACACCTACGCGGGCGACGAGTTCGCCGCGGCGGTCGCGGCCATGATCGC
CGCCACCGACCGCGCGGCGCTGGACGCGTCGGAGGGCGAGCGCGCGCGGATGCACCGGGCCTTCACGCAGGCCACCCGGC
TCGAGTGGCAGTTCTGGGACAGCGCCTACCGCGACGCGGCCTGGACCCTGTGA

Upstream 100 bases:

>100_bases
GACCAACGCCTGCTCGCAGATGCGCCAGAAGCTCGGCGTGCGCACCCTCGCCGAGCTGATCCACGTCGCCGTCACCCACG
CGCAGCGGCAGGGCTAGGCC

Downstream 100 bases:

>100_bases
GCCGCCCGGCGCGCCCGTGACCGCGCCGGAGACCCGCCGCGATCTCGTCGCGGCCGCGCTCGCGGCCGCCCTGGCCGCGC
CGCTCCGTCCGGCCCTGGCG

Product: TenA family transcriptional regulator

Products: NA

Alternate protein names: Thiaminase II; Transcriptional activator tenA [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MASPGLAGALGAFSQEAWARNAAAYETIRSMPFNAELAAGTLPQDRFRHYIVQDAHYLIGFGRALSLAAAKAPDPDTIVQ
FSRAAQEAIVVERALHGGFFRDYGIGPETFAATPLTPACDHYVCYLVATAYAEPYAVLCAALLPCFWIYKAVGDDIFARA
APDNPYRAWIDTYAGDEFAAAVAAMIAATDRAALDASEGERARMHRAFTQATRLEWQFWDSAYRDAAWTL

Sequences:

>Translated_230_residues
MASPGLAGALGAFSQEAWARNAAAYETIRSMPFNAELAAGTLPQDRFRHYIVQDAHYLIGFGRALSLAAAKAPDPDTIVQ
FSRAAQEAIVVERALHGGFFRDYGIGPETFAATPLTPACDHYVCYLVATAYAEPYAVLCAALLPCFWIYKAVGDDIFARA
APDNPYRAWIDTYAGDEFAAAVAAMIAATDRAALDASEGERARMHRAFTQATRLEWQFWDSAYRDAAWTL
>Mature_229_residues
ASPGLAGALGAFSQEAWARNAAAYETIRSMPFNAELAAGTLPQDRFRHYIVQDAHYLIGFGRALSLAAAKAPDPDTIVQF
SRAAQEAIVVERALHGGFFRDYGIGPETFAATPLTPACDHYVCYLVATAYAEPYAVLCAALLPCFWIYKAVGDDIFARAA
PDNPYRAWIDTYAGDEFAAAVAAMIAATDRAALDASEGERARMHRAFTQATRLEWQFWDSAYRDAAWTL

Specific function: Stimulates the production of several extracellular degradative enzymes at the transcriptional level, probably by interfering with degS and degU, which are required for this effect. Is not an essential protein, but affects the sporulation frequency [H]

COG id: COG0819

COG function: function code K; Putative transcription activator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiaminase-2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016084
- InterPro:   IPR004305 [H]

Pfam domain/function: PF03070 TENA_THI-4 [H]

EC number: =3.5.99.2 [H]

Molecular weight: Translated: 25102; Mature: 24971

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASPGLAGALGAFSQEAWARNAAAYETIRSMPFNAELAAGTLPQDRFRHYIVQDAHYLIG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
FGRALSLAAAKAPDPDTIVQFSRAAQEAIVVERALHGGFFRDYGIGPETFAATPLTPACD
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHCCCCCCCCCHH
HYVCYLVATAYAEPYAVLCAALLPCFWIYKAVGDDIFARAAPDNPYRAWIDTYAGDEFAA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHCCHHHHH
AVAAMIAATDRAALDASEGERARMHRAFTQATRLEWQFWDSAYRDAAWTL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASPGLAGALGAFSQEAWARNAAAYETIRSMPFNAELAAGTLPQDRFRHYIVQDAHYLIG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
FGRALSLAAAKAPDPDTIVQFSRAAQEAIVVERALHGGFFRDYGIGPETFAATPLTPACD
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHCCCCCCCCCHH
HYVCYLVATAYAEPYAVLCAALLPCFWIYKAVGDDIFARAAPDNPYRAWIDTYAGDEFAA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHCCHHHHH
AVAAMIAATDRAALDASEGERARMHRAFTQATRLEWQFWDSAYRDAAWTL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1898926; 9384377 [H]