Click here to switch to the map view.

The map label for this gene is ycgM [H]

Identifier: 170749785

GI number: 170749785

Start: 3593158

End: 3593940

Strand: Direct

Name: ycgM [H]

Synonym: Mrad2831_3384

Alternate gene names: 170749785

Gene position: 3593158-3593940 (Clockwise)

Preceding gene: 170749784

Following gene: 170749786

Centisome position: 59.12

GC content: 72.29

Gene sequence:

>783_bases
ATGGCAACGATCGATCGACGCCGCGTGCTCGGGGCGGTCGCCGCCGGCGCCGCCGCGGGCCTCGGCCCCGCCGCGGCCGC
CGAGGCGCAGCCGGACCCGCTGTTCCCGCTCGCGCAGGCCACCATCCCGATCCTGGGCGAGGCGCAGGTCTTCCCGGTCC
GCCGGATCTACTGCATCGGCCGCAACTACGCGGCCCATGCCCGCGAGATGGGCTCCGACCCGTCGCGCGAGCCGCCCTTC
TTCTTCCAGAAACCGGCGGATGCCGTGCAGGTCGTGGCGGGCGGCGTCGCCGAGCATCCCTACCCGTCGCTGACCCAGAA
CTACCACCACGAGATCGAGCTCGTCGCAGTGCTGAAGTCGGGCGGCCGCGACGTCCCGGCCGCGCAGGCGCTCGACCACG
TCTACGGCTACGCCACCGGCCTCGACATGACCCGCCGGGACCTCCAGCGCGGGATGGGTAACCAGAAGAAGCCGTGGGAG
ATCGGCAAGAGCTTCGACCGTTCCGCGCCCATCACGCCGATCCTGCCCGTCGTCCGGGCCGGGCATCCAACCCGCGGCCG
CATCCGGCTCGCCGTGAACGGCACCGTGCGGCAGGACGCCGACCTGTCGGAGATGATCTGGTCGGTGGCCGAGCAGATCG
CGGAGCTGTCGCGGGCCTTCGAGCTCAAGGCCGGCGACATCGTCTTCTCCGGGACGCCCGAGAATGTCGGGCCGGTCGTC
CGCGGGGACGTGCTCGCGGGCTCGATCGCGGGCCTGCCGGACCTGTCGATCCGCATCGTCTGA

Upstream 100 bases:

>100_bases
GCCTGAGCCTTTCCATCCCAGCCGCGGACCGCTGGCGGCCGGTCCCGCCCGGTCGTATCGCCCGCATGCGGCGCACGGAT
CGCGGTGAAGGGACAGAGGC

Downstream 100 bases:

>100_bases
TCCCGCATCGTTTGACGCTCCCCCCGCGGCGACGCGGCGCCGGCGGGACGACGACTTTCCCTGCCGGCGGCGCGGCTCTA
TCCCGTACGGATCCGCGGGG

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MATIDRRRVLGAVAAGAAAGLGPAAAAEAQPDPLFPLAQATIPILGEAQVFPVRRIYCIGRNYAAHAREMGSDPSREPPF
FFQKPADAVQVVAGGVAEHPYPSLTQNYHHEIELVAVLKSGGRDVPAAQALDHVYGYATGLDMTRRDLQRGMGNQKKPWE
IGKSFDRSAPITPILPVVRAGHPTRGRIRLAVNGTVRQDADLSEMIWSVAEQIAELSRAFELKAGDIVFSGTPENVGPVV
RGDVLAGSIAGLPDLSIRIV

Sequences:

>Translated_260_residues
MATIDRRRVLGAVAAGAAAGLGPAAAAEAQPDPLFPLAQATIPILGEAQVFPVRRIYCIGRNYAAHAREMGSDPSREPPF
FFQKPADAVQVVAGGVAEHPYPSLTQNYHHEIELVAVLKSGGRDVPAAQALDHVYGYATGLDMTRRDLQRGMGNQKKPWE
IGKSFDRSAPITPILPVVRAGHPTRGRIRLAVNGTVRQDADLSEMIWSVAEQIAELSRAFELKAGDIVFSGTPENVGPVV
RGDVLAGSIAGLPDLSIRIV
>Mature_259_residues
ATIDRRRVLGAVAAGAAAGLGPAAAAEAQPDPLFPLAQATIPILGEAQVFPVRRIYCIGRNYAAHAREMGSDPSREPPFF
FQKPADAVQVVAGGVAEHPYPSLTQNYHHEIELVAVLKSGGRDVPAAQALDHVYGYATGLDMTRRDLQRGMGNQKKPWEI
GKSFDRSAPITPILPVVRAGHPTRGRIRLAVNGTVRQDADLSEMIWSVAEQIAELSRAFELKAGDIVFSGTPENVGPVVR
GDVLAGSIAGLPDLSIRIV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI215422413, Length=203, Percent_Identity=40.3940886699507, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI13654274, Length=206, Percent_Identity=38.8349514563107, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI66348062, Length=199, Percent_Identity=40.2010050251256, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI156231349, Length=205, Percent_Identity=31.219512195122, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI40786394, Length=221, Percent_Identity=30.7692307692308, Blast_Score=96, Evalue=3e-20,
Organism=Escherichia coli, GI1787428, Length=211, Percent_Identity=36.4928909952607, Blast_Score=139, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17557057, Length=194, Percent_Identity=33.5051546391753, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6324161, Length=219, Percent_Identity=30.1369863013699, Blast_Score=102, Evalue=8e-23,
Organism=Drosophila melanogaster, GI28572127, Length=215, Percent_Identity=32.093023255814, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI28571789, Length=211, Percent_Identity=27.0142180094787, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 27739; Mature: 27608

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIDRRRVLGAVAAGAAAGLGPAAAAEAQPDPLFPLAQATIPILGEAQVFPVRRIYCIG
CCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCHHHHHCCCCCCCCEECCCEEEEEEC
RNYAAHAREMGSDPSREPPFFFQKPADAVQVVAGGVAEHPYPSLTQNYHHEIELVAVLKS
CCHHHHHHHHCCCCCCCCCCCEECCHHHHHHHHCCCCCCCCCCHHHCCCHHEEEEEEECC
GGRDVPAAQALDHVYGYATGLDMTRRDLQRGMGNQKKPWEIGKSFDRSAPITPILPVVRA
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCHHHHHHHC
GHPTRGRIRLAVNGTVRQDADLSEMIWSVAEQIAELSRAFELKAGDIVFSGTPENVGPVV
CCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCE
RGDVLAGSIAGLPDLSIRIV
ECCHHCCHHCCCCCCEEEEC
>Mature Secondary Structure 
ATIDRRRVLGAVAAGAAAGLGPAAAAEAQPDPLFPLAQATIPILGEAQVFPVRRIYCIG
CCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCHHHHHCCCCCCCCEECCCEEEEEEC
RNYAAHAREMGSDPSREPPFFFQKPADAVQVVAGGVAEHPYPSLTQNYHHEIELVAVLKS
CCHHHHHHHHCCCCCCCCCCCEECCHHHHHHHHCCCCCCCCCCHHHCCCHHEEEEEEECC
GGRDVPAAQALDHVYGYATGLDMTRRDLQRGMGNQKKPWEIGKSFDRSAPITPILPVVRA
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCHHHHHHHC
GHPTRGRIRLAVNGTVRQDADLSEMIWSVAEQIAELSRAFELKAGDIVFSGTPENVGPVV
CCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCE
RGDVLAGSIAGLPDLSIRIV
ECCHHCCHHCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]