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The map label for this gene is yfbT [H]

Identifier: 170749784

GI number: 170749784

Start: 3592398

End: 3593063

Strand: Direct

Name: yfbT [H]

Synonym: Mrad2831_3383

Alternate gene names: 170749784

Gene position: 3592398-3593063 (Clockwise)

Preceding gene: 170749779

Following gene: 170749785

Centisome position: 59.11

GC content: 74.62

Gene sequence:

>666_bases
ATGCCCGAGTCAGCCCTCCCGTCGCGCCCCCTGGCGGCGCTCCTGTTCGACATGGACGGGACGATCATCAGCTCGATCGC
CTCCGCGGAGCGGATCTGGTCGCGCTGGGCCGAGGCGCACGGCCTCGACGCGGCGTCCTTCCTGCCGACGATCCACGGCG
TGCAGTCGGTCGAGACCATCCGGCGGCTGAACCTGCCGGGCGTCGATCCCGTGGCCGAGGCCGCCGCGATCACCGAGGCC
GAGATGGCGGATGTCGACGACATCGTGGCCATCCCGGGGGCGCGGGCCTTCCTGGAGGCGCTGCCGCGCCACCGCTGGGC
GATCGTCACCTCGGCGCCCCGGCGGCTGGCGGAGCGCCGCCTCGCGGCGGCCGGCATGCCGGTCCCCGACCTTCTCGTGG
CCGCCGAGGACGTAGCGCGGGGCAAGCCCGCGCCGGACTGCTTCCTGCTGGCGGCCGGACGCCTCGGCGTCGCGGCGGCG
GACTGCCTCGTGTTCGAGGACGCCCCGGCCGGCATCCGTGCGGCCGAGGCCGCGGATGCGGCCGTCGTGGTCGTCACCGC
CACCCATCACGAGCCGGTGAGGACCAATCATCCCACGATTGCCGACTACACCGGGCTGCGCGTCGCGGCCGCGGCGGAGG
GGATCCGGGTGACACAAACCGCCTGA

Upstream 100 bases:

>100_bases
GACCCCGGGCGAAGGCGTCCCGGAGGCCCGGCCGCCCGCGAGACGCGGCCATGCGCGCGGGCCGGTTGCCGGGACGGCGG
CGCCGGCCTAGCCCTCGCCC

Downstream 100 bases:

>100_bases
GCCTTTCCATCCCAGCCGCGGACCGCTGGCGGCCGGTCCCGCCCGGTCGTATCGCCCGCATGCGGCGCACGGATCGCGGT
GAAGGGACAGAGGCATGGCA

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MPESALPSRPLAALLFDMDGTIISSIASAERIWSRWAEAHGLDAASFLPTIHGVQSVETIRRLNLPGVDPVAEAAAITEA
EMADVDDIVAIPGARAFLEALPRHRWAIVTSAPRRLAERRLAAAGMPVPDLLVAAEDVARGKPAPDCFLLAAGRLGVAAA
DCLVFEDAPAGIRAAEAADAAVVVVTATHHEPVRTNHPTIADYTGLRVAAAAEGIRVTQTA

Sequences:

>Translated_221_residues
MPESALPSRPLAALLFDMDGTIISSIASAERIWSRWAEAHGLDAASFLPTIHGVQSVETIRRLNLPGVDPVAEAAAITEA
EMADVDDIVAIPGARAFLEALPRHRWAIVTSAPRRLAERRLAAAGMPVPDLLVAAEDVARGKPAPDCFLLAAGRLGVAAA
DCLVFEDAPAGIRAAEAADAAVVVVTATHHEPVRTNHPTIADYTGLRVAAAAEGIRVTQTA
>Mature_220_residues
PESALPSRPLAALLFDMDGTIISSIASAERIWSRWAEAHGLDAASFLPTIHGVQSVETIRRLNLPGVDPVAEAAAITEAE
MADVDDIVAIPGARAFLEALPRHRWAIVTSAPRRLAERRLAAAGMPVPDLLVAAEDVARGKPAPDCFLLAAGRLGVAAAD
CLVFEDAPAGIRAAEAADAAVVVVTATHHEPVRTNHPTIADYTGLRVAAAAEGIRVTQTA

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrate glucose 6-phosphate [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI87082080, Length=179, Percent_Identity=41.8994413407821, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789046, Length=176, Percent_Identity=36.9318181818182, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790151, Length=205, Percent_Identity=27.8048780487805, Blast_Score=65, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321833, Length=241, Percent_Identity=30.7053941908714, Blast_Score=101, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6321834, Length=232, Percent_Identity=30.6034482758621, Blast_Score=96, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320905, Length=183, Percent_Identity=27.8688524590164, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322136, Length=181, Percent_Identity=28.7292817679558, Blast_Score=68, Evalue=9e-13,
Organism=Drosophila melanogaster, GI116008157, Length=216, Percent_Identity=29.6296296296296, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17137324, Length=211, Percent_Identity=28.436018957346, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 23096; Mature: 22964

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPESALPSRPLAALLFDMDGTIISSIASAERIWSRWAEAHGLDAASFLPTIHGVQSVETI
CCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RRLNLPGVDPVAEAAAITEAEMADVDDIVAIPGARAFLEALPRHRWAIVTSAPRRLAERR
HHCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHCCCCCEEEEEHHHHHHHHHH
LAAAGMPVPDLLVAAEDVARGKPAPDCFLLAAGRLGVAAADCLVFEDAPAGIRAAEAADA
HHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHEEEECCCCCCCCHHCCCCC
AVVVVTATHHEPVRTNHPTIADYTGLRVAAAAEGIRVTQTA
EEEEEEECCCCCCCCCCCCCCCCCCEEEEHHHCCEEEECCC
>Mature Secondary Structure 
PESALPSRPLAALLFDMDGTIISSIASAERIWSRWAEAHGLDAASFLPTIHGVQSVETI
CCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RRLNLPGVDPVAEAAAITEAEMADVDDIVAIPGARAFLEALPRHRWAIVTSAPRRLAERR
HHCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHCCCCCEEEEEHHHHHHHHHH
LAAAGMPVPDLLVAAEDVARGKPAPDCFLLAAGRLGVAAADCLVFEDAPAGIRAAEAADA
HHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHEEEECCCCCCCCHHCCCCC
AVVVVTATHHEPVRTNHPTIADYTGLRVAAAAEGIRVTQTA
EEEEEEECCCCCCCCCCCCCCCCCCEEEEHHHCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 10493123 [H]