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The map label for this gene is gstA [H]

Identifier: 170749726

GI number: 170749726

Start: 3526532

End: 3527149

Strand: Direct

Name: gstA [H]

Synonym: Mrad2831_3325

Alternate gene names: 170749726

Gene position: 3526532-3527149 (Clockwise)

Preceding gene: 170749713

Following gene: 170749727

Centisome position: 58.02

GC content: 72.98

Gene sequence:

>618_bases
ATGAAGCTCTACCACCATCCCCTCTCGGGCCACGCGCACCGGGCGCGCCTGTTCCTGTCCCTGGTCGACGCCCCGCACGA
GCTGATCGAGGTCGACTTGAAGGCGGGCGCGCACAAGACGCCGGCCTTCCTCGCCCTGAACCCGTTCGGTCAGGTGCCGG
TGCTCGACGACGACGGCGTGATCGTCTCCGATTCCAACGCCATCCTCGTCTACGTGGCGAAGCGGCTCGGCCGGTCCGAC
TGGCTGCCCGAGGATCCGCGCGGCGCGGCGGCGGTCCAGCGCTGGCTCTCGGTCGCGGCGGGCGAGCTCGCCTACGGCCC
GGCGGCCGCGCGGCTGATCACGGTCTTCGGCGCCAAGTTCTCTCCGGAGGAGGTGATCGGCCGGGCGCACACGCTCCTGG
GACGGATCGAGGCACATCTCGACGGGCGGGACTGGCTCGCGGCCGAGCGGCCGACCATCGCGGACGTGGCGGTCTACAGC
TACCTCGCCCGCGCCCCGGAGGGGAACGTGGACCTGTCGGGCTACCCGCGGGTCGAGGCCTTCCTGCGCCGGGTCGAGGG
CCTGCCGGGCTTCGTCCCCTTCGCCGAGACTCCCGCGGGCCTCACGGCGGCGGCGTGA

Upstream 100 bases:

>100_bases
GAATGATGAACTGCGCAGAACGCGCATTCTGCTCGCCCGGAAGCGACGGCATTCTCCTCATACGGCCCGGGGCGATCCCG
GCCCCCGACGGAGATCCACC

Downstream 100 bases:

>100_bases
CCAGAAGAGCCCCGGGCGCACCCGCGCCCGGGAGCTGGACCGCGTGGAGGAGGCGGAGATGGCTGACGGTCAAACCTTTG
CGACGCTGCCGACCTGGCAT

Product: glutathione S-transferase domain-containing protein

Products: HX; R-S-glutathione

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MKLYHHPLSGHAHRARLFLSLVDAPHELIEVDLKAGAHKTPAFLALNPFGQVPVLDDDGVIVSDSNAILVYVAKRLGRSD
WLPEDPRGAAAVQRWLSVAAGELAYGPAAARLITVFGAKFSPEEVIGRAHTLLGRIEAHLDGRDWLAAERPTIADVAVYS
YLARAPEGNVDLSGYPRVEAFLRRVEGLPGFVPFAETPAGLTAAA

Sequences:

>Translated_205_residues
MKLYHHPLSGHAHRARLFLSLVDAPHELIEVDLKAGAHKTPAFLALNPFGQVPVLDDDGVIVSDSNAILVYVAKRLGRSD
WLPEDPRGAAAVQRWLSVAAGELAYGPAAARLITVFGAKFSPEEVIGRAHTLLGRIEAHLDGRDWLAAERPTIADVAVYS
YLARAPEGNVDLSGYPRVEAFLRRVEGLPGFVPFAETPAGLTAAA
>Mature_205_residues
MKLYHHPLSGHAHRARLFLSLVDAPHELIEVDLKAGAHKTPAFLALNPFGQVPVLDDDGVIVSDSNAILVYVAKRLGRSD
WLPEDPRGAAAVQRWLSVAAGELAYGPAAARLITVFGAKFSPEEVIGRAHTLLGRIEAHLDGRDWLAAERPTIADVAVYS
YLARAPEGNVDLSGYPRVEAFLRRVEGLPGFVPFAETPAGLTAAA

Specific function: Unknown

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI4504187, Length=200, Percent_Identity=28.5, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI124249394, Length=200, Percent_Identity=28.5, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788640, Length=204, Percent_Identity=27.4509803921569, Blast_Score=69, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922526, Length=200, Percent_Identity=31, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI20130115, Length=182, Percent_Identity=31.8681318681319, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19922532, Length=181, Percent_Identity=32.5966850828729, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI17933730, Length=187, Percent_Identity=24.5989304812834, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24654992, Length=181, Percent_Identity=30.3867403314917, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17864592, Length=180, Percent_Identity=27.2222222222222, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17864598, Length=181, Percent_Identity=27.6243093922652, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17864596, Length=193, Percent_Identity=23.8341968911917, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20130123, Length=197, Percent_Identity=29.4416243654822, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571670, Length=164, Percent_Identity=27.4390243902439, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24654979, Length=180, Percent_Identity=28.8888888888889, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24654983, Length=181, Percent_Identity=28.7292817679558, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24654965, Length=183, Percent_Identity=29.5081967213115, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221378141, Length=169, Percent_Identity=30.1775147928994, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17864594, Length=179, Percent_Identity=25.6983240223464, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24646259, Length=185, Percent_Identity=28.6486486486486, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI221378983, Length=185, Percent_Identity=28.6486486486486, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI85725204, Length=163, Percent_Identity=26.9938650306748, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17737923, Length=163, Percent_Identity=26.9938650306748, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI19922528, Length=195, Percent_Identity=31.7948717948718, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45549270, Length=140, Percent_Identity=30.7142857142857, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24654975, Length=167, Percent_Identity=29.3413173652695, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI62472445, Length=183, Percent_Identity=30.0546448087432, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24654996, Length=181, Percent_Identity=30.3867403314917, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: 2.5.1.18

Molecular weight: Translated: 22042; Mature: 22042

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYHHPLSGHAHRARLFLSLVDAPHELIEVDLKAGAHKTPAFLALNPFGQVPVLDDDGV
CCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEECCCCCCCEECCCCE
IVSDSNAILVYVAKRLGRSDWLPEDPRGAAAVQRWLSVAAGELAYGPAAARLITVFGAKF
EEECCCEEEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHCHHHCCHHHHHHHHHHCCCC
SPEEVIGRAHTLLGRIEAHLDGRDWLAAERPTIADVAVYSYLARAPEGNVDLSGYPRVEA
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHH
FLRRVEGLPGFVPFAETPAGLTAAA
HHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKLYHHPLSGHAHRARLFLSLVDAPHELIEVDLKAGAHKTPAFLALNPFGQVPVLDDDGV
CCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEECCCCCCCEECCCCE
IVSDSNAILVYVAKRLGRSDWLPEDPRGAAAVQRWLSVAAGELAYGPAAARLITVFGAKF
EEECCCEEEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHCHHHCCHHHHHHHHHHCCCC
SPEEVIGRAHTLLGRIEAHLDGRDWLAAERPTIADVAVYSYLARAPEGNVDLSGYPRVEA
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHH
FLRRVEGLPGFVPFAETPAGLTAAA
HHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA