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The map label for this gene is ompR [H]

Identifier: 170749688

GI number: 170749688

Start: 3486537

End: 3487298

Strand: Reverse

Name: ompR [H]

Synonym: Mrad2831_3286

Alternate gene names: 170749688

Gene position: 3487298-3486537 (Counterclockwise)

Preceding gene: 170749691

Following gene: 170749687

Centisome position: 57.38

GC content: 71.26

Gene sequence:

>762_bases
ATGACCATTCCAGACAGCCCCGCCCCCGGCACCGCCCGCGGCGTCGCGGCGATCCCGTCGATCGCCGTGGTCGACGACGA
GGCGGCGACCCGCGAGATGGTCGGGGATTACCTCAAGCTCCACGGGTTCGCGGTGGTCCTGTGCGATGGCGGGCGCGCCC
TGCGCGAGCACCTCGCCCACCACAGTCCCGACCTGATCGTGCTCGACCTGAACATGCCCGAGGAGGACGGGCTCTCCATC
GTGCGCGACCTCAAGGCCCGCACGGCGATCCCGATCATCATGCTCACCGCCACGGCGAGCGCGATCGACCGCGTGGTCGG
GCTGGAGCTCGGGGCCGACGATTACCTGCCCAAACCGTGCGAGTTGCGGGAGCTGGTCGCCCGCGTGCGATCGGTGCTGC
GCCGCGTGCAGATGCCGGGCGCCGCGCCGGCCCCGGCTCCCGTGGGCGGACGCCGGATCCGGTTCGGCACCAAGTGGCTG
GAACTCGACGCGCTGCGCCTGAGCGACGATGCCGGTCTGGAGCAGGCGCTCACCCGCTCGGAATTCGATCTGCTGAAGGC
CTTCGCCGACAACCCGCGGCGCGCGCTCTCGCGCGAGCGCCTGCTCGACCTCGCCGACGCCCGCGACCCGGACGCGTTCG
ACCGCGCCATCGACGTGCGGATCAACCGCATCCGCAAGAAGGTCGAGCCGGATCCCGGCAATCCGCGCTACATCCGGACC
GTGCGGGGTCTCGGATACATATTCCGCCCCGAGGGCGACTGA

Upstream 100 bases:

>100_bases
ACTACGCTAGAAATCGTGTTGAAAACTTGTCACGGTAACGTGAGCCGATACGATTCCTGCATTCGTTCCAGAGCGAACCC
GGAAAGTGCGCACCGCTGCG

Downstream 100 bases:

>100_bases
TGTTCCCAGCTCAATGTTGCGTCGTGACGTGACAACGCAACAATTCGTGCTCCGACTTGGGCTGGAAGCAATATCGGCGG
TACCGAGCTACCCTATCAGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTIPDSPAPGTARGVAAIPSIAVVDDEAATREMVGDYLKLHGFAVVLCDGGRALREHLAHHSPDLIVLDLNMPEEDGLSI
VRDLKARTAIPIIMLTATASAIDRVVGLELGADDYLPKPCELRELVARVRSVLRRVQMPGAAPAPAPVGGRRIRFGTKWL
ELDALRLSDDAGLEQALTRSEFDLLKAFADNPRRALSRERLLDLADARDPDAFDRAIDVRINRIRKKVEPDPGNPRYIRT
VRGLGYIFRPEGD

Sequences:

>Translated_253_residues
MTIPDSPAPGTARGVAAIPSIAVVDDEAATREMVGDYLKLHGFAVVLCDGGRALREHLAHHSPDLIVLDLNMPEEDGLSI
VRDLKARTAIPIIMLTATASAIDRVVGLELGADDYLPKPCELRELVARVRSVLRRVQMPGAAPAPAPVGGRRIRFGTKWL
ELDALRLSDDAGLEQALTRSEFDLLKAFADNPRRALSRERLLDLADARDPDAFDRAIDVRINRIRKKVEPDPGNPRYIRT
VRGLGYIFRPEGD
>Mature_252_residues
TIPDSPAPGTARGVAAIPSIAVVDDEAATREMVGDYLKLHGFAVVLCDGGRALREHLAHHSPDLIVLDLNMPEEDGLSIV
RDLKARTAIPIIMLTATASAIDRVVGLELGADDYLPKPCELRELVARVRSVLRRVQMPGAAPAPAPVGGRRIRFGTKWLE
LDALRLSDDAGLEQALTRSEFDLLKAFADNPRRALSRERLLDLADARDPDAFDRAIDVRINRIRKKVEPDPGNPRYIRTV
RGLGYIFRPEGD

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=239, Percent_Identity=44.3514644351464, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=40.2597402597403, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=32.6086956521739, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788394, Length=238, Percent_Identity=36.5546218487395, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=39.6551724137931, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=36.6379310344828, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI2367329, Length=242, Percent_Identity=38.4297520661157, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1786911, Length=234, Percent_Identity=35.4700854700855, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1786784, Length=237, Percent_Identity=38.3966244725738, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=30.1255230125523, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082012, Length=233, Percent_Identity=33.0472103004292, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=31.8777292576419, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787375, Length=238, Percent_Identity=29.8319327731092, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790552, Length=232, Percent_Identity=31.4655172413793, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788550, Length=125, Percent_Identity=34.4, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1790299, Length=118, Percent_Identity=33.0508474576271, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=34.2105263157895, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27777; Mature: 27646

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIPDSPAPGTARGVAAIPSIAVVDDEAATREMVGDYLKLHGFAVVLCDGGRALREHLAH
CCCCCCCCCCCCCCHHHCCCEEEECCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHH
HSPDLIVLDLNMPEEDGLSIVRDLKARTAIPIIMLTATASAIDRVVGLELGADDYLPKPC
CCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHEECCCCCCCCCH
ELRELVARVRSVLRRVQMPGAAPAPAPVGGRRIRFGTKWLELDALRLSDDAGLEQALTRS
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCEEEEEEEEECCCCCHHHHHHHH
EFDLLKAFADNPRRALSRERLLDLADARDPDAFDRAIDVRINRIRKKVEPDPGNPRYIRT
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
VRGLGYIFRPEGD
EHHCCEEECCCCC
>Mature Secondary Structure 
TIPDSPAPGTARGVAAIPSIAVVDDEAATREMVGDYLKLHGFAVVLCDGGRALREHLAH
CCCCCCCCCCCCCHHHCCCEEEECCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHH
HSPDLIVLDLNMPEEDGLSIVRDLKARTAIPIIMLTATASAIDRVVGLELGADDYLPKPC
CCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHEECCCCCCCCCH
ELRELVARVRSVLRRVQMPGAAPAPAPVGGRRIRFGTKWLELDALRLSDDAGLEQALTRS
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCEEEEEEEEECCCCCHHHHHHHH
EFDLLKAFADNPRRALSRERLLDLADARDPDAFDRAIDVRINRIRKKVEPDPGNPRYIRT
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
VRGLGYIFRPEGD
EHHCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]