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The map label for this gene is glpR [H]

Identifier: 170749672

GI number: 170749672

Start: 3464993

End: 3465754

Strand: Reverse

Name: glpR [H]

Synonym: Mrad2831_3270

Alternate gene names: 170749672

Gene position: 3465754-3464993 (Counterclockwise)

Preceding gene: 170749680

Following gene: 170749671

Centisome position: 57.02

GC content: 69.16

Gene sequence:

>762_bases
ATGCTCTCGGAGCGTCAGAACGCGATCATGGACATCGCGCGGACCGAAGGGCGTGTCTCGGTCGACGCCCTATCCGGTCG
GTTCGCGGTCAGCGTGCAGACCATCCGGAAGGATCTCAACGACCTGTGCGACGCGCGTCTGCTTTCGCGCATCCACGGCG
GGGCCGTGCTCGGCGCGGGGGCCGAGAACCTCGACTACGAGGCCCGCAACGCGCTGGCGGCGCCCGAGAAGGCGGCGATC
GCGCGCGCGGCCGCCGACCTGATCCCGGACCGCTCCTCGCTGTTCATCAATATCGGTACCACCACCGAGGCCGTTGCCCG
GGCGCTCCTCGGCCATTCCGGGCTCATGGTGATCACCAACAACCTCAACGTCGCGCTCGCCCTGCGGCCGAGCCCCGAGA
TCGAGTGCATCGTGGCGGGCGGCCTGATCCGTCGCTCGGACGGCGGGATCGTGGGGGAGGCGGCGGTGGACTTCATCCGC
CAGTTCAAGGTCGATTTCGCGGTGATCGGGGCCTCGGCGATCGACGAGGACGGGGCGCTCCTCGATTTCGATTATCGCGA
GGTCCGGGTCGCCCAGGCGATCATCGCCAACGCCCGCCACGTCGTGCTGGTCGCGGATTCCACCAAGTTCGAGCGGAGCG
CCCCGGTCCGGCTCGCCCAGCTCGGCCAGATCGGAACCTTCGTGACCGATCGCTGCCCCAGCGAGACGCTGCGCGACCTC
TGTCGCGCGTCCGGCGTCCGCCTCGTCGAAACCGGTCGTTGA

Upstream 100 bases:

>100_bases
GGCGTGGTCGCCGGTCCAGAACGCGCTTTCGCTTTCTCATGACGCTCGCGCGCTCGCACCGAGAAGAGGTTTCGTTTTCG
TCGCGCGGAGGTCTGCAGGT

Downstream 100 bases:

>100_bases
GCGTATCGCTTTCGATTGACTTTCCTTTGGTTTCGTATTCAATTCCTCTGCTTTCGCAGTCGCGCGCCGGACGCCGCGAC
ACGAAAGGGGGAGGATCATG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MLSERQNAIMDIARTEGRVSVDALSGRFAVSVQTIRKDLNDLCDARLLSRIHGGAVLGAGAENLDYEARNALAAPEKAAI
ARAAADLIPDRSSLFINIGTTTEAVARALLGHSGLMVITNNLNVALALRPSPEIECIVAGGLIRRSDGGIVGEAAVDFIR
QFKVDFAVIGASAIDEDGALLDFDYREVRVAQAIIANARHVVLVADSTKFERSAPVRLAQLGQIGTFVTDRCPSETLRDL
CRASGVRLVETGR

Sequences:

>Translated_253_residues
MLSERQNAIMDIARTEGRVSVDALSGRFAVSVQTIRKDLNDLCDARLLSRIHGGAVLGAGAENLDYEARNALAAPEKAAI
ARAAADLIPDRSSLFINIGTTTEAVARALLGHSGLMVITNNLNVALALRPSPEIECIVAGGLIRRSDGGIVGEAAVDFIR
QFKVDFAVIGASAIDEDGALLDFDYREVRVAQAIIANARHVVLVADSTKFERSAPVRLAQLGQIGTFVTDRCPSETLRDL
CRASGVRLVETGR
>Mature_253_residues
MLSERQNAIMDIARTEGRVSVDALSGRFAVSVQTIRKDLNDLCDARLLSRIHGGAVLGAGAENLDYEARNALAAPEKAAI
ARAAADLIPDRSSLFINIGTTTEAVARALLGHSGLMVITNNLNVALALRPSPEIECIVAGGLIRRSDGGIVGEAAVDFIR
QFKVDFAVIGASAIDEDGALLDFDYREVRVAQAIIANARHVVLVADSTKFERSAPVRLAQLGQIGTFVTDRCPSETLRDL
CRASGVRLVETGR

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=246, Percent_Identity=46.3414634146341, Blast_Score=231, Evalue=3e-62,
Organism=Escherichia coli, GI87082344, Length=245, Percent_Identity=39.1836734693878, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI1788069, Length=248, Percent_Identity=30.241935483871, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789519, Length=254, Percent_Identity=29.9212598425197, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1789059, Length=251, Percent_Identity=28.2868525896414, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI226510968, Length=228, Percent_Identity=32.8947368421053, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789170, Length=234, Percent_Identity=27.3504273504274, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790753, Length=230, Percent_Identity=26.5217391304348, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787063, Length=250, Percent_Identity=24.4, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787540, Length=210, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 26948; Mature: 26948

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSERQNAIMDIARTEGRVSVDALSGRFAVSVQTIRKDLNDLCDARLLSRIHGGAVLGAG
CCCCHHHHHHHHHHCCCCEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEECC
AENLDYEARNALAAPEKAAIARAAADLIPDRSSLFINIGTTTEAVARALLGHSGLMVITN
CCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCCEEEEEE
NLNVALALRPSPEIECIVAGGLIRRSDGGIVGEAAVDFIRQFKVDFAVIGASAIDEDGAL
CCEEEEEECCCCCEEEEEECCEEEECCCCEEHHHHHHHHHHHHHHHEEEECCCCCCCCCE
LDFDYREVRVAQAIIANARHVVLVADSTKFERSAPVRLAQLGQIGTFVTDRCPSETLRDL
EECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
CRASGVRLVETGR
HHHCCCEEEECCC
>Mature Secondary Structure
MLSERQNAIMDIARTEGRVSVDALSGRFAVSVQTIRKDLNDLCDARLLSRIHGGAVLGAG
CCCCHHHHHHHHHHCCCCEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEECC
AENLDYEARNALAAPEKAAIARAAADLIPDRSSLFINIGTTTEAVARALLGHSGLMVITN
CCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCCEEEEEE
NLNVALALRPSPEIECIVAGGLIRRSDGGIVGEAAVDFIRQFKVDFAVIGASAIDEDGAL
CCEEEEEECCCCCEEEEEECCEEEECCCCEEHHHHHHHHHHHHHHHEEEECCCCCCCCCE
LDFDYREVRVAQAIIANARHVVLVADSTKFERSAPVRLAQLGQIGTFVTDRCPSETLRDL
EECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
CRASGVRLVETGR
HHHCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]