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The map label for this gene is hexR [C]

Identifier: 170749649

GI number: 170749649

Start: 3440271

End: 3441209

Strand: Reverse

Name: hexR [C]

Synonym: Mrad2831_3246

Alternate gene names: 170749649

Gene position: 3441209-3440271 (Counterclockwise)

Preceding gene: 170749650

Following gene: 170749648

Centisome position: 56.62

GC content: 74.33

Gene sequence:

>939_bases
GTGGCACTGCAACCTGGGGAAGCATCTGTCGCCCAGCGCATCGCGCAGGCGTACCCGTCCCTCAGCGCCGCCCATCGGCA
GGTTGCCCGCTTCGTCCTCGATCACCCGCTCCGCGCCGCGACGCTCCCGGTCAACGAGCTGGCGGATCTCGTCGGCGTCT
CCGTCGCGACCGCCAACCGGTTCGCCCGCGCTGTCGGCTACGCGGGCTACGCGAAGTTCCGCGCGGCCCTCGTCCTCGGC
TACGAGAAGGCGCTCGCCCCGGTCGAGAAGCTGCGCGGCGGCCGGGAGCAGCCCACGACCGTGTCCGGGATCCTCGACGG
GGCCCTGGCCGACATCGTCCGCAACATCGAGGCGACGCGGCGCGGGCTCGACGGCGAGACGTGCGGCCGCGCGGTCGAGG
CGATCCGGCAGGCCCGGCGAGTCTACGTGGTGGGCCTGGGCAGCAGCAGCTGGCCGGCCGGCATCCTCGCGCGCAACCTC
GACGTGAACCGCGAGGACGTCCACCTGCTGGCGACGCTGGAGGGGCCGGGCTTCGCCGCGCGGACCCTGCGCCGGCTGAC
GGCCGACGACCTCGTCATCGCCCTCGCCACCCCGCGCTACTTCGCCGACACGGTGCGGCTCGCCGAGATCGCCCGGAAGC
ACGGCGCCGCGGTGCTGGCGCTGACCGACGGCCCGCACTCGCCCCTCGTGGCGACCGCCACCCTCGCGCTCTACGCCCAG
ACGGACTGCCACTACTTCGCGGCCTCGGATGCCAGCCTGACGGCCCTCGTCGAGGCCCTCGCGAGCGCCTTCGCCCACGC
GACCGTGGATCTGGTGCCGGCCGCGACGCGGGTGACGGAAGCGGTGCTGCCCTGGCTCGACCGCGACTACGCCGCCTGGC
CGCCGCAGGGCGGAGCCGACGACCTGTCCGACACACCGCCTCCGGGAACCGTTCCATGA

Upstream 100 bases:

>100_bases
TGCAGGGGATGCCACCGGAAGCGGCAGGTCTCGGCTTGCAAATGATCTAAAAGTTTCTCAATCTCGGCTCAGTTGAGAAT
TTTCGATCGGGCCTGGCGCC

Downstream 100 bases:

>100_bases
GCGACCACCGCCCCGTTCTCGTGATCCACGGCGGCGCCGGGACGATCGCGCAGAATCAGGATGATCCGGGCGAGGCGCGC
TACCACGCGGCCCTCGCGGA

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MALQPGEASVAQRIAQAYPSLSAAHRQVARFVLDHPLRAATLPVNELADLVGVSVATANRFARAVGYAGYAKFRAALVLG
YEKALAPVEKLRGGREQPTTVSGILDGALADIVRNIEATRRGLDGETCGRAVEAIRQARRVYVVGLGSSSWPAGILARNL
DVNREDVHLLATLEGPGFAARTLRRLTADDLVIALATPRYFADTVRLAEIARKHGAAVLALTDGPHSPLVATATLALYAQ
TDCHYFAASDASLTALVEALASAFAHATVDLVPAATRVTEAVLPWLDRDYAAWPPQGGADDLSDTPPPGTVP

Sequences:

>Translated_312_residues
MALQPGEASVAQRIAQAYPSLSAAHRQVARFVLDHPLRAATLPVNELADLVGVSVATANRFARAVGYAGYAKFRAALVLG
YEKALAPVEKLRGGREQPTTVSGILDGALADIVRNIEATRRGLDGETCGRAVEAIRQARRVYVVGLGSSSWPAGILARNL
DVNREDVHLLATLEGPGFAARTLRRLTADDLVIALATPRYFADTVRLAEIARKHGAAVLALTDGPHSPLVATATLALYAQ
TDCHYFAASDASLTALVEALASAFAHATVDLVPAATRVTEAVLPWLDRDYAAWPPQGGADDLSDTPPPGTVP
>Mature_311_residues
ALQPGEASVAQRIAQAYPSLSAAHRQVARFVLDHPLRAATLPVNELADLVGVSVATANRFARAVGYAGYAKFRAALVLGY
EKALAPVEKLRGGREQPTTVSGILDGALADIVRNIEATRRGLDGETCGRAVEAIRQARRVYVVGLGSSSWPAGILARNLD
VNREDVHLLATLEGPGFAARTLRRLTADDLVIALATPRYFADTVRLAEIARKHGAAVLALTDGPHSPLVATATLALYAQT
DCHYFAASDASLTALVEALASAFAHATVDLVPAATRVTEAVLPWLDRDYAAWPPQGGADDLSDTPPPGTVP

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=266, Percent_Identity=25.187969924812, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 32896; Mature: 32764

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALQPGEASVAQRIAQAYPSLSAAHRQVARFVLDHPLRAATLPVNELADLVGVSVATANR
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHH
FARAVGYAGYAKFRAALVLGYEKALAPVEKLRGGREQPTTVSGILDGALADIVRNIEATR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RGLDGETCGRAVEAIRQARRVYVVGLGSSSWPAGILARNLDVNREDVHLLATLEGPGFAA
CCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHCCCCCCCCEEEEEEECCCCHHH
RTLRRLTADDLVIALATPRYFADTVRLAEIARKHGAAVLALTDGPHSPLVATATLALYAQ
HHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHEEE
TDCHYFAASDASLTALVEALASAFAHATVDLVPAATRVTEAVLPWLDRDYAAWPPQGGAD
CCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DLSDTPPPGTVP
CCCCCCCCCCCC
>Mature Secondary Structure 
ALQPGEASVAQRIAQAYPSLSAAHRQVARFVLDHPLRAATLPVNELADLVGVSVATANR
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHH
FARAVGYAGYAKFRAALVLGYEKALAPVEKLRGGREQPTTVSGILDGALADIVRNIEATR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RGLDGETCGRAVEAIRQARRVYVVGLGSSSWPAGILARNLDVNREDVHLLATLEGPGFAA
CCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHCCCCCCCCEEEEEEECCCCHHH
RTLRRLTADDLVIALATPRYFADTVRLAEIARKHGAAVLALTDGPHSPLVATATLALYAQ
HHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHEEE
TDCHYFAASDASLTALVEALASAFAHATVDLVPAATRVTEAVLPWLDRDYAAWPPQGGAD
CCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DLSDTPPPGTVP
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]