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The map label for this gene is infC [H]

Identifier: 170749563

GI number: 170749563

Start: 3340690

End: 3341211

Strand: Reverse

Name: infC [H]

Synonym: Mrad2831_3158

Alternate gene names: 170749563

Gene position: 3341211-3340690 (Counterclockwise)

Preceding gene: 170749564

Following gene: 170749562

Centisome position: 54.97

GC content: 63.98

Gene sequence:

>522_bases
ATGCCGGCCCCGCAGAAGGACGGGCCGCGCGCGAACCGCGACATTCGCGGTGTGCGGGAAGTGCAGCTGATCGACGATAC
CGGGCAGAACCGCGGCGTCGTCCCCTTCTTCGACGCCCTGAACCTGGCCGAGGAAGTCGGTCTCGATCTCGTGGAGATCG
CGCCGAATTCCGTGCCGCCCGTCTGCAAGCTGCTCGATTACGGGCGCTTCCGCTTCAACGAGCAGAAGAAGCAGAACGAG
GCCCGCAAGCGGCAGAAGACCGTCGAGGTGAAGGAGATCAAGCTCCGTCCCGGCATCGACAAGCACGACTACGACACCAA
GATGAAGTCGGTTCACCGCTTCTTCGAGGAGGGCGACAAGGTCAAGGTGACCCTGCGCTTCCGCGGTCGTGAGATGGCTC
ACCAGGATATCGGTCTGCGCCTCCTGGAGCGCGTGAAGAGCGAGACCGCCGAGATCGCCAAGGTCGAGAGCGAGCCGATG
CTCGAAGGCCGGCAGATGATCATGATCCTCGCGCCGCGCTGA

Upstream 100 bases:

>100_bases
GATGAAACCGGGACGGCAGGCGGTCAGGAGATCCTCCTGGGGATCCGCCGTTTCGCCGTTGCAGCAGGAGACCTAAGCCA
TTCGTAGACCGATGAGAGCC

Downstream 100 bases:

>100_bases
GCGGCCCGGATCCAGGGACGCGAGACTTGCGCCGCCTCCTCACAGGGGCGGCGTTGTCTTTTCAGCGCTTCCGATCGGCG
CCGCCGCGGATTATGGGCAG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MPAPQKDGPRANRDIRGVREVQLIDDTGQNRGVVPFFDALNLAEEVGLDLVEIAPNSVPPVCKLLDYGRFRFNEQKKQNE
ARKRQKTVEVKEIKLRPGIDKHDYDTKMKSVHRFFEEGDKVKVTLRFRGREMAHQDIGLRLLERVKSETAEIAKVESEPM
LEGRQMIMILAPR

Sequences:

>Translated_173_residues
MPAPQKDGPRANRDIRGVREVQLIDDTGQNRGVVPFFDALNLAEEVGLDLVEIAPNSVPPVCKLLDYGRFRFNEQKKQNE
ARKRQKTVEVKEIKLRPGIDKHDYDTKMKSVHRFFEEGDKVKVTLRFRGREMAHQDIGLRLLERVKSETAEIAKVESEPM
LEGRQMIMILAPR
>Mature_172_residues
PAPQKDGPRANRDIRGVREVQLIDDTGQNRGVVPFFDALNLAEEVGLDLVEIAPNSVPPVCKLLDYGRFRFNEQKKQNEA
RKRQKTVEVKEIKLRPGIDKHDYDTKMKSVHRFFEEGDKVKVTLRFRGREMAHQDIGLRLLERVKSETAEIAKVESEPML
EGRQMIMILAPR

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=165, Percent_Identity=55.1515151515151, Blast_Score=171, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 19949; Mature: 19818

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPQKDGPRANRDIRGVREVQLIDDTGQNRGVVPFFDALNLAEEVGLDLVEIAPNSVPP
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCH
VCKLLDYGRFRFNEQKKQNEARKRQKTVEVKEIKLRPGIDKHDYDTKMKSVHRFFEEGDK
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHEEEECCCCCCCCHHHHHHHHHHHHHCCCE
VKVTLRFRGREMAHQDIGLRLLERVKSETAEIAKVESEPMLEGRQMIMILAPR
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
PAPQKDGPRANRDIRGVREVQLIDDTGQNRGVVPFFDALNLAEEVGLDLVEIAPNSVPP
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCH
VCKLLDYGRFRFNEQKKQNEARKRQKTVEVKEIKLRPGIDKHDYDTKMKSVHRFFEEGDK
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHEEEECCCCCCCCHHHHHHHHHHHHHCCCE
VKVTLRFRGREMAHQDIGLRLLERVKSETAEIAKVESEPMLEGRQMIMILAPR
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA