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The map label for this gene is moeZ [H]

Identifier: 170749562

GI number: 170749562

Start: 3339801

End: 3340586

Strand: Reverse

Name: moeZ [H]

Synonym: Mrad2831_3157

Alternate gene names: 170749562

Gene position: 3340586-3339801 (Counterclockwise)

Preceding gene: 170749563

Following gene: 170749556

Centisome position: 54.96

GC content: 74.17

Gene sequence:

>786_bases
ATGGCCCTCGCCCCCGACGAGATCGAACGCTACGCCCGCCACCTCGTCCTGGCCGAGGTCGGCGGTCCCGGTCAGGCCCG
GATCAAGGCCGCCCGGATCCTCGTCGTCGGGGCGGGCGGGCTCGGCGCGCCGCTGATCCAGTACCTCGCCGCCGCGGGGA
TCGGCACGATCGGCCTCGTCGACGACGACACGGTCTCCCTGTCGAATCTGCAGCGGCAGGTGATCCACGGGACGCCGGAT
CTCGGCCGGCCGAAGGTCGAGAGCGCGGCCGACGCGGTGGCGCGCCTCAACCCGCACGTGACGGTCGTCCGGCACCCGTT
CCGGATCGACGCGGGCAACGCCGTCGACCTCATCGCCGGCTACGACCTCGTGGCCGACGGATCCGACAACTTCGCCACGC
GCTACGCGGTGTCGGACGCCTGCTTCCGGGCGGGGCGCCCGCTGGTGACGGCGGCGCTGGGCCGCTTCGACGGCACGCTG
ACCACGATCCGCGCGCACGAGACCGGGGCCGACGGGACTCCGAACCCGACCTATCGCTGCCTCTTCCCGAACCCGCCTCC
GCCCGGCAGCGTGCCCGCCTGCGCGGAGGCCGGCGTGCTCGGCGCGCTCGCCGGCGTCATGGGCTCGCTGATGGCCATGG
AGGTGATCCGCGCCGTGGCGGGCTTCGGCGAGCCGCTGGTCGGGCGCCTCCTCATGGTCGACGCCCGCGCGATGCGGTTC
GAGACCCTGACCTACGGCTGGGATCCCGAGAACCCGCTCAGCGGCAGCGGCGCCTCAGCCGCCTAG

Upstream 100 bases:

>100_bases
GCCCGGATCCAGGGACGCGAGACTTGCGCCGCCTCCTCACAGGGGCGGCGTTGTCTTTTCAGCGCTTCCGATCGGCGCCG
CCGCGGATTATGGGCAGGTT

Downstream 100 bases:

>100_bases
CGGCTCCGGCGGCATCCACGGTCCCTCCGCCTCCGCCTTGCCGAGGCAGCACTTCTTGAACTTCCTCCCCGAGCCGCACG
GGCAGGGGTCGTTGCGGCCG

Product: UBA/THIF-type NAD/FAD binding protein

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MALAPDEIERYARHLVLAEVGGPGQARIKAARILVVGAGGLGAPLIQYLAAAGIGTIGLVDDDTVSLSNLQRQVIHGTPD
LGRPKVESAADAVARLNPHVTVVRHPFRIDAGNAVDLIAGYDLVADGSDNFATRYAVSDACFRAGRPLVTAALGRFDGTL
TTIRAHETGADGTPNPTYRCLFPNPPPPGSVPACAEAGVLGALAGVMGSLMAMEVIRAVAGFGEPLVGRLLMVDARAMRF
ETLTYGWDPENPLSGSGASAA

Sequences:

>Translated_261_residues
MALAPDEIERYARHLVLAEVGGPGQARIKAARILVVGAGGLGAPLIQYLAAAGIGTIGLVDDDTVSLSNLQRQVIHGTPD
LGRPKVESAADAVARLNPHVTVVRHPFRIDAGNAVDLIAGYDLVADGSDNFATRYAVSDACFRAGRPLVTAALGRFDGTL
TTIRAHETGADGTPNPTYRCLFPNPPPPGSVPACAEAGVLGALAGVMGSLMAMEVIRAVAGFGEPLVGRLLMVDARAMRF
ETLTYGWDPENPLSGSGASAA
>Mature_260_residues
ALAPDEIERYARHLVLAEVGGPGQARIKAARILVVGAGGLGAPLIQYLAAAGIGTIGLVDDDTVSLSNLQRQVIHGTPDL
GRPKVESAADAVARLNPHVTVVRHPFRIDAGNAVDLIAGYDLVADGSDNFATRYAVSDACFRAGRPLVTAALGRFDGTLT
TIRAHETGADGTPNPTYRCLFPNPPPPGSVPACAEAGVLGALAGVMGSLMAMEVIRAVAGFGEPLVGRLLMVDARAMRFE
TLTYGWDPENPLSGSGASAA

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=234, Percent_Identity=51.2820512820513, Blast_Score=202, Evalue=2e-52,
Organism=Homo sapiens, GI4885649, Length=161, Percent_Identity=33.5403726708075, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI38045942, Length=114, Percent_Identity=34.2105263157895, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI38045944, Length=114, Percent_Identity=34.2105263157895, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI23510338, Length=187, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI23510340, Length=187, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI38045948, Length=161, Percent_Identity=31.055900621118, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787048, Length=254, Percent_Identity=42.1259842519685, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI87082356, Length=235, Percent_Identity=37.0212765957447, Blast_Score=140, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI17540406, Length=249, Percent_Identity=41.7670682730924, Blast_Score=201, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI193203301, Length=171, Percent_Identity=28.0701754385965, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71984476, Length=112, Percent_Identity=34.8214285714286, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321903, Length=220, Percent_Identity=42.7272727272727, Blast_Score=198, Evalue=6e-52,
Organism=Saccharomyces cerevisiae, GI6320598, Length=183, Percent_Identity=27.8688524590164, Blast_Score=79, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24582879, Length=233, Percent_Identity=45.4935622317597, Blast_Score=208, Evalue=4e-54,
Organism=Drosophila melanogaster, GI24660640, Length=168, Percent_Identity=29.1666666666667, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28573937, Length=187, Percent_Identity=30.4812834224599, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 26945; Mature: 26814

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALAPDEIERYARHLVLAEVGGPGQARIKAARILVVGAGGLGAPLIQYLAAAGIGTIGLV
CCCCHHHHHHHHHHEEEEECCCCCHHEEEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEC
DDDTVSLSNLQRQVIHGTPDLGRPKVESAADAVARLNPHVTVVRHPFRIDAGNAVDLIAG
CCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCEEECCCCEEEEEEC
YDLVADGSDNFATRYAVSDACFRAGRPLVTAALGRFDGTLTTIRAHETGADGTPNPTYRC
CEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEE
LFPNPPPPGSVPACAEAGVLGALAGVMGSLMAMEVIRAVAGFGEPLVGRLLMVDARAMRF
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEE
ETLTYGWDPENPLSGSGASAA
EEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ALAPDEIERYARHLVLAEVGGPGQARIKAARILVVGAGGLGAPLIQYLAAAGIGTIGLV
CCCHHHHHHHHHHEEEEECCCCCHHEEEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEC
DDDTVSLSNLQRQVIHGTPDLGRPKVESAADAVARLNPHVTVVRHPFRIDAGNAVDLIAG
CCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCEEECCCCEEEEEEC
YDLVADGSDNFATRYAVSDACFRAGRPLVTAALGRFDGTLTTIRAHETGADGTPNPTYRC
CEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEE
LFPNPPPPGSVPACAEAGVLGALAGVMGSLMAMEVIRAVAGFGEPLVGRLLMVDARAMRF
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEE
ETLTYGWDPENPLSGSGASAA
EEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]