Click here to switch to the map view.

The map label for this gene is trpD

Identifier: 170749505

GI number: 170749505

Start: 3277840

End: 3278877

Strand: Reverse

Name: trpD

Synonym: Mrad2831_3100

Alternate gene names: 170749505

Gene position: 3278877-3277840 (Counterclockwise)

Preceding gene: 170749506

Following gene: 170749504

Centisome position: 53.95

GC content: 75.63

Gene sequence:

>1038_bases
ATGGACAGCTTCAGACCCCATCTCGCGAAGGTCGCCGGGGGCCTCGCCCTCGACCGCGCCGAGGCCCGCGCCGCCTTCGA
CGACCTGCTGTCGGGCGAGGTCACGCCGGTCCAGGCCGGCGCCTTCCTGACCGCCCTCAAGGTGCGCGGCGAGAGCGTCG
AGGAGATCGTCGGCGCGGCCGAGGCCATGCGGGCGCGCATGACGCGCGTCGCGGCGCCGGAGAACGCCGTCGACGTCGTC
GGCACCGGCGGTGACCATTCCGGCAGCGTGAACGTCTCGACCCTGGCGGCGATCGTCGTGGCCGCCTGCGGCGTGCCGGT
GGCGAAGCACGGGAACCGCGCGGCGACCTCGCGCTCCGGCGCCGCCGACGTGCTCGCGGCCCTGGGCGTCCGGCTCGGGC
TCGACCCCGCCGCGCAGGCCCGCTGCCTCGACGAGGCCGGCCTCTGCTTCCTGTTCGCGCAGGCTCACCACCCGGCGATG
CGCCACGTCGCGGCGGTCCGGTCCGAGCTGCCCGTGCGGACGATCTTCAACCTGCTCGGCCCGCTGAGCAACCCGGCCGG
CGTGGGCTACCAGCTCTTCGGCGTCGCCCAGGCGGCTCTCGCGGAGCCGCTGACGCGGGTCCTGGCCGAACTCGGCAGCC
GCCGGGTCTGGACCGTCCACGGATCCGATGGGCTCGACGAGATCACCGTCACCGGCCCGACGCAGGTCGTCGCCCTCGAC
GAAGGCCGGTTGTGCCACTTCACCATCGACCCGCGCGAATTCGGGCTGGCGCTGCGCGCGCCCGAGGAGCTGCGCGGCGG
CGACCCGGCCGACAACGCGCGGTCCCTGGAGGCCGTCCTGGCGGGTGCGCGGAACGCCTATCGGGACATCGCGGTCCTCA
ACGCCGGGGCGGCGCTCGTGGTCGCGGGGGCCGCGCAGGCCCTGGCGGACGGCGTCGCGCAGGCGCAGGATGCCGTCGAT
TCCGGGGCCGCCCGGGCGACGCTCGCCCGCCTCGTCCGGGCCTCGAACGACCACTCCAACGGGCAGGAGGGCCGATGA

Upstream 100 bases:

>100_bases
AACTTCCTGGATCTCGCCGCCGCCTGGAACACGGCGCGTGACAGGACGCGCGCCGACGTGCATTGACGCCGGGGGCCGGG
GCGGCCCTCCGTAAGAACTC

Downstream 100 bases:

>100_bases
GCTCGCTGACGCACGAGGCGACCCCGGAGACCGGCGCCGGGACCCCGACCGAGCGGCCGAACGTCCTCGCCCGCATCGAG
GCCTACAAGCGCCGCGAGAT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MDSFRPHLAKVAGGLALDRAEARAAFDDLLSGEVTPVQAGAFLTALKVRGESVEEIVGAAEAMRARMTRVAAPENAVDVV
GTGGDHSGSVNVSTLAAIVVAACGVPVAKHGNRAATSRSGAADVLAALGVRLGLDPAAQARCLDEAGLCFLFAQAHHPAM
RHVAAVRSELPVRTIFNLLGPLSNPAGVGYQLFGVAQAALAEPLTRVLAELGSRRVWTVHGSDGLDEITVTGPTQVVALD
EGRLCHFTIDPREFGLALRAPEELRGGDPADNARSLEAVLAGARNAYRDIAVLNAGAALVVAGAAQALADGVAQAQDAVD
SGAARATLARLVRASNDHSNGQEGR

Sequences:

>Translated_345_residues
MDSFRPHLAKVAGGLALDRAEARAAFDDLLSGEVTPVQAGAFLTALKVRGESVEEIVGAAEAMRARMTRVAAPENAVDVV
GTGGDHSGSVNVSTLAAIVVAACGVPVAKHGNRAATSRSGAADVLAALGVRLGLDPAAQARCLDEAGLCFLFAQAHHPAM
RHVAAVRSELPVRTIFNLLGPLSNPAGVGYQLFGVAQAALAEPLTRVLAELGSRRVWTVHGSDGLDEITVTGPTQVVALD
EGRLCHFTIDPREFGLALRAPEELRGGDPADNARSLEAVLAGARNAYRDIAVLNAGAALVVAGAAQALADGVAQAQDAVD
SGAARATLARLVRASNDHSNGQEGR
>Mature_345_residues
MDSFRPHLAKVAGGLALDRAEARAAFDDLLSGEVTPVQAGAFLTALKVRGESVEEIVGAAEAMRARMTRVAAPENAVDVV
GTGGDHSGSVNVSTLAAIVVAACGVPVAKHGNRAATSRSGAADVLAALGVRLGLDPAAQARCLDEAGLCFLFAQAHHPAM
RHVAAVRSELPVRTIFNLLGPLSNPAGVGYQLFGVAQAALAEPLTRVLAELGSRRVWTVHGSDGLDEITVTGPTQVVALD
EGRLCHFTIDPREFGLALRAPEELRGGDPADNARSLEAVLAGARNAYRDIAVLNAGAALVVAGAAQALADGVAQAQDAVD
SGAARATLARLVRASNDHSNGQEGR

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=282, Percent_Identity=40.7801418439716, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1787019, Length=313, Percent_Identity=24.9201277955272, Blast_Score=79, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6320561, Length=324, Percent_Identity=31.1728395061728, Blast_Score=134, Evalue=2e-32,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_METRJ (B1M5Q2)

Other databases:

- EMBL:   CP001001
- RefSeq:   YP_001755765.1
- ProteinModelPortal:   B1M5Q2
- SMR:   B1M5Q2
- GeneID:   6139146
- GenomeReviews:   CP001001_GR
- KEGG:   mrd:Mrad2831_3100
- HOGENOM:   HBG559996
- OMA:   ATPSQMG
- ProtClustDB:   PRK00188
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35337; Mature: 35337

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSFRPHLAKVAGGLALDRAEARAAFDDLLSGEVTPVQAGAFLTALKVRGESVEEIVGAA
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCHHHHHHHHH
EAMRARMTRVAAPENAVDVVGTGGDHSGSVNVSTLAAIVVAACGVPVAKHGNRAATSRSG
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHCCCCCHHCCCCC
AADVLAALGVRLGLDPAAQARCLDEAGLCFLFAQAHHPAMRHVAAVRSELPVRTIFNLLG
HHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEHHCCHHHHHHHHHHHCCCHHHHHHHHC
PLSNPAGVGYQLFGVAQAALAEPLTRVLAELGSRRVWTVHGSDGLDEITVTGPTQVVALD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCEEEEEEC
EGRLCHFTIDPREFGLALRAPEELRGGDPADNARSLEAVLAGARNAYRDIAVLNAGAALV
CCCEEEEEECHHHHCEEECCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHH
VAGAAQALADGVAQAQDAVDSGAARATLARLVRASNDHSNGQEGR
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MDSFRPHLAKVAGGLALDRAEARAAFDDLLSGEVTPVQAGAFLTALKVRGESVEEIVGAA
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCHHHHHHHHH
EAMRARMTRVAAPENAVDVVGTGGDHSGSVNVSTLAAIVVAACGVPVAKHGNRAATSRSG
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHCCCCCHHCCCCC
AADVLAALGVRLGLDPAAQARCLDEAGLCFLFAQAHHPAMRHVAAVRSELPVRTIFNLLG
HHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEHHCCHHHHHHHHHHHCCCHHHHHHHHC
PLSNPAGVGYQLFGVAQAALAEPLTRVLAELGSRRVWTVHGSDGLDEITVTGPTQVVALD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCEEEEEEC
EGRLCHFTIDPREFGLALRAPEELRGGDPADNARSLEAVLAGARNAYRDIAVLNAGAALV
CCCEEEEEECHHHHCEEECCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHH
VAGAAQALADGVAQAQDAVDSGAARATLARLVRASNDHSNGQEGR
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA