| Definition | Methylobacterium radiotolerans JCM 2831 chromosome, complete genome. |
|---|---|
| Accession | NC_010505 |
| Length | 6,077,833 |
Click here to switch to the map view.
The map label for this gene is fabG [H]
Identifier: 170749474
GI number: 170749474
Start: 3241415
End: 3242182
Strand: Reverse
Name: fabG [H]
Synonym: Mrad2831_3069
Alternate gene names: 170749474
Gene position: 3242182-3241415 (Counterclockwise)
Preceding gene: 170749475
Following gene: 170749473
Centisome position: 53.34
GC content: 72.79
Gene sequence:
>768_bases GTGAGCGTCGCCGTCACACCGCGCCGGGTCCTCGTGACCGGCGGCGCGTCCGGGATCGGCGCCGCGATCGTCCGCGCCCT GGCGGGAGCCGGTCTCGGCGTCGACTTCACCTACCGCGCCTCGGCCGAGGCCGCGCAGGCGCTGCTGGCCGAGCTTCGGG CGACCTACCCGGACCGGCCGTTCGCGGCCCATGCCGTTGACCTCGCCGACCGGGCAGGGCTGGAGCTGTTCTGCGAGGCC GCCGAGGCGACGGGCTATTACGGTCTCGTCCACAATGCCGGCCAGTCCTGCGACGCCCTCGCGGCGATGCTCGATCAGGA GCGGGCCGAGGCCGCCATGCAGGTCAATTTCTTCTCGCTGACGCGCCTCGCCAAGGCGCTGGTGCGGGAGATGACCCGCG CGCGCGCGGGCCGCATCGTGGCGATCGGGTCCGTCGCCGCCCTGCGGGCCAATGCCGGCAACGCCGCCTACGCGGCGACC AAGGGCGCGCTCATCGCGTATTGTCGGACCCTGGCGATGGAGACGGCCAAGCGCGGCGTGACCGTCAACGTGATCGCCCC GGGCTTCGTCGACACCGCCATGATGGAGCGCTACGCCGCCTACCGGGACGGCATGGAGCGCCAGATTCCGATCGGCCGCT TCGGCCGGCCCGAGGATGTCGCGGCGCTGGCGGCCTTCCTGATGGGCGAGGGGGCATCCTACATCACCGGCACCGTGCTG CCCGTCGATGGCGGCCTGACCGCCATGATGGGCGTCCACCGGACCTGA
Upstream 100 bases:
>100_bases TCGTGGAGACTGCCCGCGACCTGCCGGTGCGGACCGTGCTGTCGAACTCGTTCGGCTTCGGCGGCCAGAACACCTGCCTG GTCCTCGGCGCGGAGCCCGC
Downstream 100 bases:
>100_bases CGGTGGCGCCGCCGAACCGGACGACCCTGACGATGCGCGCCAGCCTCGCCCTCACCGCCGCCCTCTGCGGCGCGGCTCTC CTGGCCCCGGGCCACGCCCG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 255; Mature: 254
Protein sequence:
>255_residues MSVAVTPRRVLVTGGASGIGAAIVRALAGAGLGVDFTYRASAEAAQALLAELRATYPDRPFAAHAVDLADRAGLELFCEA AEATGYYGLVHNAGQSCDALAAMLDQERAEAAMQVNFFSLTRLAKALVREMTRARAGRIVAIGSVAALRANAGNAAYAAT KGALIAYCRTLAMETAKRGVTVNVIAPGFVDTAMMERYAAYRDGMERQIPIGRFGRPEDVAALAAFLMGEGASYITGTVL PVDGGLTAMMGVHRT
Sequences:
>Translated_255_residues MSVAVTPRRVLVTGGASGIGAAIVRALAGAGLGVDFTYRASAEAAQALLAELRATYPDRPFAAHAVDLADRAGLELFCEA AEATGYYGLVHNAGQSCDALAAMLDQERAEAAMQVNFFSLTRLAKALVREMTRARAGRIVAIGSVAALRANAGNAAYAAT KGALIAYCRTLAMETAKRGVTVNVIAPGFVDTAMMERYAAYRDGMERQIPIGRFGRPEDVAALAAFLMGEGASYITGTVL PVDGGLTAMMGVHRT >Mature_254_residues SVAVTPRRVLVTGGASGIGAAIVRALAGAGLGVDFTYRASAEAAQALLAELRATYPDRPFAAHAVDLADRAGLELFCEAA EATGYYGLVHNAGQSCDALAAMLDQERAEAAMQVNFFSLTRLAKALVREMTRARAGRIVAIGSVAALRANAGNAAYAATK GALIAYCRTLAMETAKRGVTVNVIAPGFVDTAMMERYAAYRDGMERQIPIGRFGRPEDVAALAAFLMGEGASYITGTVLP VDGGLTAMMGVHRT
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=33.6099585062241, Blast_Score=117, Evalue=1e-26, Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=30.5555555555556, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI15277342, Length=248, Percent_Identity=32.6612903225806, Blast_Score=98, Evalue=8e-21, Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=30.2788844621514, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI126723750, Length=143, Percent_Identity=34.965034965035, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI19923817, Length=246, Percent_Identity=28.4552845528455, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI66933014, Length=217, Percent_Identity=26.2672811059908, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI59889578, Length=136, Percent_Identity=37.5, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=29.0983606557377, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI20149619, Length=194, Percent_Identity=29.8969072164948, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=39.0041493775934, Blast_Score=139, Evalue=2e-34, Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=36.8421052631579, Blast_Score=115, Evalue=3e-27, Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=33.59375, Blast_Score=94, Evalue=6e-21, Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=31.1284046692607, Blast_Score=91, Evalue=7e-20, Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=28.740157480315, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=26.3779527559055, Blast_Score=80, Evalue=9e-17, Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=30.4878048780488, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=29.8804780876494, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI87082160, Length=243, Percent_Identity=27.9835390946502, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=27.0491803278689, Blast_Score=75, Evalue=6e-15, Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=31.0204081632653, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1786701, Length=195, Percent_Identity=30.7692307692308, Blast_Score=66, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=31.8725099601594, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI25147288, Length=260, Percent_Identity=28.4615384615385, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=31.4176245210728, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=31.3008130081301, Blast_Score=94, Evalue=9e-20, Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=28.030303030303, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=26.8939393939394, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=31.2977099236641, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=29.0566037735849, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17551412, Length=271, Percent_Identity=30.2583025830258, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=30.952380952381, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=28.735632183908, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=29.811320754717, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=29.8850574712644, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=30, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=27.0676691729323, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=28.3524904214559, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=26.6666666666667, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=29.5880149812734, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=27.3809523809524, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17565030, Length=271, Percent_Identity=29.1512915129151, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17560332, Length=272, Percent_Identity=30.8823529411765, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=28.1124497991968, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=29.5546558704453, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17538182, Length=250, Percent_Identity=27.6, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17508651, Length=248, Percent_Identity=24.5967741935484, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=156, Percent_Identity=28.8461538461538, Blast_Score=66, Evalue=6e-12, Organism=Drosophila melanogaster, GI24639444, Length=258, Percent_Identity=33.3333333333333, Blast_Score=109, Evalue=1e-24, Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=31.5175097276265, Blast_Score=95, Evalue=4e-20, Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=30.7692307692308, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=31.0756972111554, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=32.421875, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI21357041, Length=256, Percent_Identity=30.859375, Blast_Score=84, Evalue=7e-17, Organism=Drosophila melanogaster, GI24644337, Length=120, Percent_Identity=37.5, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=29.2181069958848, Blast_Score=81, Evalue=5e-16, Organism=Drosophila melanogaster, GI21356301, Length=199, Percent_Identity=29.1457286432161, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24665264, Length=195, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=30.0518134715026, Blast_Score=66, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26551; Mature: 26420
Theoretical pI: Translated: 8.45; Mature: 8.45
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 4.3 %Met (Translated Protein) 5.5 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 3.9 %Met (Mature Protein) 5.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSVAVTPRRVLVTGGASGIGAAIVRALAGAGLGVDFTYRASAEAAQALLAELRATYPDRP CCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCC FAAHAVDLADRAGLELFCEAAEATGYYGLVHNAGQSCDALAAMLDQERAEAAMQVNFFSL CHHHHHHHHHHCCHHHHHHHHHCCCEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH TRLAKALVREMTRARAGRIVAIGSVAALRANAGNAAYAATKGALIAYCRTLAMETAKRGV HHHHHHHHHHHHHHHCCCEEEECCHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC TVNVIAPGFVDTAMMERYAAYRDGMERQIPIGRFGRPEDVAALAAFLMGEGASYITGTVL EEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHEEEEE PVDGGLTAMMGVHRT EECCCHHHHHCCCCC >Mature Secondary Structure SVAVTPRRVLVTGGASGIGAAIVRALAGAGLGVDFTYRASAEAAQALLAELRATYPDRP CCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCC FAAHAVDLADRAGLELFCEAAEATGYYGLVHNAGQSCDALAAMLDQERAEAAMQVNFFSL CHHHHHHHHHHCCHHHHHHHHHCCCEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH TRLAKALVREMTRARAGRIVAIGSVAALRANAGNAAYAATKGALIAYCRTLAMETAKRGV HHHHHHHHHHHHHHHCCCEEEECCHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC TVNVIAPGFVDTAMMERYAAYRDGMERQIPIGRFGRPEDVAALAAFLMGEGASYITGTVL EEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHEEEEE PVDGGLTAMMGVHRT EECCCHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8759840; 9384377; 9534248; 8654983 [H]