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The map label for this gene is ycgM [H]

Identifier: 170749457

GI number: 170749457

Start: 3220801

End: 3221496

Strand: Reverse

Name: ycgM [H]

Synonym: Mrad2831_3052

Alternate gene names: 170749457

Gene position: 3221496-3220801 (Counterclockwise)

Preceding gene: 170749461

Following gene: 170749456

Centisome position: 53.0

GC content: 69.97

Gene sequence:

>696_bases
ATGCTCTCCGTCATCCAGAACCCGCCCCGCATCGCGCTCCCCATCGTCGGCAGCAGCGACTTCTTCCCCGTGCGCCGCGT
CTACTGCGTCGGCCGCAACTACGCCGCCCATGCCCGTGAGATGGGTGCGGACCCGGACCGTGAGCCGCCGTTCTTCTTCA
TGAAGCCTGCCGACGCCCTGCAGATCGTCGGCCCGGAACCCACGGCCCACGCCTACCCGCCGAAGACCGCCAACTACCAT
TTCGAGGTGGAGATGGTGGCGGCCCTCGCCAGCGGCGGCAGCGACATTCCGGCCGAGACCGCGCTGGAGCACGTCTACGG
CTACGCCATCGGCCTCGACATGACCCGGCGCGACGTCCAGGACGAGGCCAAGAAGATGTCCCGGCCCTGGGACACCGCCA
AGGCCGCCGACGGTTCGGGCCCGGTCGGCGCCCTCCACCCGGTCTCCGTCATCGGCCACCCGGCGAAGGGCGCGATCACC
CTGTCGGTCGACGGCGAGATCCGCCAGAAGGGCGACCTCGCCGACATGATCTGGTCCGTCGCCGAGCAGATCGCCTACCT
TTCGGGCTACTTCGTCCTGCAGCCCGGCGACCTGATCTTCACCGGCACGCCCTCCGGCGTCGGTCCGGTCCAGCGCGGCC
AGCGCATGGTCGCGGCGATCGACGGTCTCGGCGCCATCACCCTCGACGTCGTGTGA

Upstream 100 bases:

>100_bases
GCGCCGGTATGGCGCGCGCCGATGCGAACCTTACAACGGTGATGTAGGGCCCGTGCGTCGTCGCGCCGGGCCACCCGGAC
GATCCACCGCAGAGGCAGAG

Downstream 100 bases:

>100_bases
GCCGCGCAGCCGCATGATCCTCGATCGGCCGGTCCTGCGGCGCCTGTTTCACCTCGGGGCGCTCGCGTCCCGGGGCATGA
CCCTCGGCGTGCGCGGCGTC

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MLSVIQNPPRIALPIVGSSDFFPVRRVYCVGRNYAAHAREMGADPDREPPFFFMKPADALQIVGPEPTAHAYPPKTANYH
FEVEMVAALASGGSDIPAETALEHVYGYAIGLDMTRRDVQDEAKKMSRPWDTAKAADGSGPVGALHPVSVIGHPAKGAIT
LSVDGEIRQKGDLADMIWSVAEQIAYLSGYFVLQPGDLIFTGTPSGVGPVQRGQRMVAAIDGLGAITLDVV

Sequences:

>Translated_231_residues
MLSVIQNPPRIALPIVGSSDFFPVRRVYCVGRNYAAHAREMGADPDREPPFFFMKPADALQIVGPEPTAHAYPPKTANYH
FEVEMVAALASGGSDIPAETALEHVYGYAIGLDMTRRDVQDEAKKMSRPWDTAKAADGSGPVGALHPVSVIGHPAKGAIT
LSVDGEIRQKGDLADMIWSVAEQIAYLSGYFVLQPGDLIFTGTPSGVGPVQRGQRMVAAIDGLGAITLDVV
>Mature_231_residues
MLSVIQNPPRIALPIVGSSDFFPVRRVYCVGRNYAAHAREMGADPDREPPFFFMKPADALQIVGPEPTAHAYPPKTANYH
FEVEMVAALASGGSDIPAETALEHVYGYAIGLDMTRRDVQDEAKKMSRPWDTAKAADGSGPVGALHPVSVIGHPAKGAIT
LSVDGEIRQKGDLADMIWSVAEQIAYLSGYFVLQPGDLIFTGTPSGVGPVQRGQRMVAAIDGLGAITLDVV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=206, Percent_Identity=42.2330097087379, Blast_Score=161, Evalue=6e-40,
Organism=Homo sapiens, GI215422413, Length=203, Percent_Identity=41.871921182266, Blast_Score=157, Evalue=6e-39,
Organism=Homo sapiens, GI66348062, Length=199, Percent_Identity=42.713567839196, Blast_Score=157, Evalue=7e-39,
Organism=Homo sapiens, GI156231349, Length=244, Percent_Identity=32.7868852459016, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI40786394, Length=214, Percent_Identity=32.2429906542056, Blast_Score=102, Evalue=2e-22,
Organism=Escherichia coli, GI1787428, Length=202, Percent_Identity=40.5940594059406, Blast_Score=152, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17557057, Length=189, Percent_Identity=38.6243386243386, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6324161, Length=221, Percent_Identity=29.8642533936652, Blast_Score=112, Evalue=6e-26,
Organism=Drosophila melanogaster, GI28571789, Length=225, Percent_Identity=28, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI28572127, Length=214, Percent_Identity=29.9065420560748, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 24641; Mature: 24641

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVIQNPPRIALPIVGSSDFFPVRRVYCVGRNYAAHAREMGADPDREPPFFFMKPADAL
CCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCEE
QIVGPEPTAHAYPPKTANYHFEVEMVAALASGGSDIPAETALEHVYGYAIGLDMTRRDVQ
EEECCCCCCCCCCCCCCCEEEEHEEEEHHHCCCCCCCHHHHHHHHHHHHEECCHHHHHHH
DEAKKMSRPWDTAKAADGSGPVGALHPVSVIGHPAKGAITLSVDGEIRQKGDLADMIWSV
HHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHH
AEQIAYLSGYFVLQPGDLIFTGTPSGVGPVQRGQRMVAAIDGLGAITLDVV
HHHHHHHHCEEEECCCCEEEECCCCCCCHHHHCCEEEEECCCCCEEEEEEC
>Mature Secondary Structure
MLSVIQNPPRIALPIVGSSDFFPVRRVYCVGRNYAAHAREMGADPDREPPFFFMKPADAL
CCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCEE
QIVGPEPTAHAYPPKTANYHFEVEMVAALASGGSDIPAETALEHVYGYAIGLDMTRRDVQ
EEECCCCCCCCCCCCCCCEEEEHEEEEHHHCCCCCCCHHHHHHHHHHHHEECCHHHHHHH
DEAKKMSRPWDTAKAADGSGPVGALHPVSVIGHPAKGAITLSVDGEIRQKGDLADMIWSV
HHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHH
AEQIAYLSGYFVLQPGDLIFTGTPSGVGPVQRGQRMVAAIDGLGAITLDVV
HHHHHHHHCEEEECCCCEEEECCCCCCCHHHHCCEEEEECCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]