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The map label for this gene is putA [H]

Identifier: 170749461

GI number: 170749461

Start: 3225389

End: 3229075

Strand: Reverse

Name: putA [H]

Synonym: Mrad2831_3056

Alternate gene names: 170749461

Gene position: 3229075-3225389 (Counterclockwise)

Preceding gene: 170749462

Following gene: 170749457

Centisome position: 53.13

GC content: 74.83

Gene sequence:

>3687_bases
ATGTCCGGATCCGGCGTTGTCGACGACGCAGCCGTCGGGGCCAGCGAGCCGTTCGGCCTGTTCGCGCCCGCCCTGGCGGA
CCGCTCGCCCCTGCGGCAGGCGGTGATCGCGGCCTGCCGGCGGCCCGAAGCGGGTTGCGTGGCGGCGCTCCTCGCCGAGG
CGCGCCTGCCGCCCGATGCCGCTCGGCGCGTCGCCGAGCACGCGCGGCGCCTCGTCGAGAGCCTGCGGCGGCAGGGCCGA
CGCGGCGGCGTCGAGGGTCTGATCCACGAATACGCGCTGTCCAGCCAGGAAGGCGTGGCGCTGATGTGCCTCGCCGAGGC
GCTGCTGCGCATCCCCGACGCGGCGACGCGGGACGCGCTGATCCGCGACAAGATCGCGGGCGGCGACTGGGCGGCCCATC
TCGGGCACAGTCCGTCGCCCTTCGTCAACGCGGCGACCTGGGGCCTGCTCGTGACCGGCAAGCTGACGGCGACCCGGGAC
GAGGCCGGCCTCTCCGCCGCGCTCACCCGGCTGATCGCCCGCGGCGGCGAGCCGGTGATCCGCAAAGGCGTCGACCTCGC
CATGCGGATGATGGGCGAGCAGTTCGTGGCGGGGCGGACCATCGCCGAGGCCCTGCGGCACGCGGCGCCGCTCGAGGCGA
AGGGCTTCACCTACTCGTACGACATGCTCGGCGAGGCCGCCGTGACCGCCGAGGACGCCGAGCGCTTCCGCCGCGCCTAC
GCGGAGGCCATCGCGGCGATCGGCGCGGCATCGGCCGGCCGCGGCGTGCTCCTCGGCCCCGGCATCTCGATCAAGCTGTC
GGCGCTCCACCCCCGCTACGTCCGCGCGCAGCGCGACCGGGTCCTGGCCGAGCTCTATCCCCGCGTGCTGGACTTGGCCC
GCCGCGCCATGGGCCACGGCATCGGCCTCAACATCGACGCCGAGGAGGCCGACCGCCTCGACCTGTCGCTCGACATCCTT
GAGCGGCTCGCCGCCGACCCCGAACTCGCCGGCTGGGACGGGCTCGGCTTCGTGGTCCAGGCCTACGGCAAGCGCTGCCC
CTTCGTCATCGACGTGCTGATCGACCTCGCCCGGCGGTGCCGGCGGCGGCTGATGGTGCGGCTCGTGAAGGGCGCCTACT
GGGACAGCGAGATCAAGCGGGCGCAGGTCGACGGTCTTTCGGACTTCCCGGTCTTCACCCGGAAAGTCCACACCGACGTC
TCGTACCTCGCCTGCGCGCGGCGGCTGCTCGCCGCGCCCGACGCGGTCTTCCCGCAATTCGCCACCCACAACGCCCAGAC
ACTGGCGAGCATCGTCGCGATGGCCGGCCCGGATTTCCGGCTCGGCCAGTACGAGTTCCAGTGCCTGCACGGCATGGGCG
AACCGCTCTACGAGGCCGTGATGGCCGACGCCGATCTGCAGCGGCCCTGCCGCATCTACGCACCGGTGGGCACGCACGAG
ACCCTGCTCGCCTACCTGGTGCGGCGCCTCCTGGAGAACGGGGCCAACACGTCCTTCGTCAACCGGGTCGCCGACGAGGC
CGTGCCGGTCGCGGACCTGATCGCCGACCCCGTCGCCGTCGTCGAGGCCGAGCCGGATCCCGGCGCGCCCCATCCGAGAA
TCGCGGCGCCCCGGGACCTCTACGGCCCGGGCCGCGCAAACGCGGCCGGGCTCGACCTCGCCGACGAGGCGGCTCTCGCC
AGCCTGTGGGACGGGTTGGCGGCGAGCGGCCGCACCGCGTGGCGGGCGGTGCCGTCGGGCGCGGATGCCGCGGCGGCCGA
CGAACCCGTGCGCAATCCCGCCGACCGCCGGGACATCGTGGGATACGACCGGCCGGCGACGGCCGGGACCGTGGCGATCG
CCGTGGCGCGGGCGGAGGCGGGCGCGGCCGGCTGGGCGGCGACGCCAGCCACAGAGCGCGCCGCCTGCCTGCGGCGGGCC
GCCGACGCCCTCGAGGCGCAGATGCCGACGCTGATCGGGCTCGTCGTGCGTGAGGCAGGCAAGACCTGCGCGAGCGCCGT
CGCGGAGATCCGCGAGGCGGTCGACTTCCTCCGCTACGACGCCGCCGAGGCCGAGCGGACTCTCGGGAACGCGCACGCGC
CGCTCGGCCCGGTCGCCTGCATCGCGCCGTGGAATTTCCCGCTGGCGATCTTCGTCGGTCAGGTCGCGGCCGCCCTGGCG
GCGGGCAACACGGTCCTGGCGAAACCCGCCGAGGAGACGCCGCTGATCGCGGCGGCTGCGGTCCGCGCGCTGCACGCGGC
CGGGATCCCCGCGGAGGCGCTGCACCTCCTGCCGGGCGACGGCAGGGTCGGCGCCGCCCTGGTCGAGGATCCGCGCGTGC
AGGGCGTGATGTTCACCGGATCGACGGCCGTGGCCAAGGGCATCCAGCGCGCTCTGGCGGAGCGACTGAACCGCTTCGAC
GAGCCGGTGCCGTTCCTGGCCGAGACCGGCGGCCAGAACGCCCTCGTGGTCGATTCCTCGGCGCTCGCCGAGCAGGTGGT
GGCCGACGTGATCGCCTCGGCCTTCGATTCCGCGGGCCAGCGCTGCTCCGCGCTCCGGATCCTGTGCCTGCAGGAGGAGA
TCGCCGACCGGACGCTGCACATGCTGAAAGGCGCCCTCCGGGAGTTGCGGGTGGGCGATCCGCGGCGCCTCGCCGTCGAC
GTCGGGCCGGTCATCACCGCCGAGGCCGCCGATCGGATCATCGGCCACGTGGCGCACATGCGCGCGCGAGGCTTCCCGGT
GGCGCAGTTCCCCCTGCCGCCCGAAGCCGACGCCGGGACCTTCGTGCCGCCGACCCTGATCGAGATCGGGGCCGTCGCCG
ATGTCGAGCAGGAGGTGTTCGGGCCGGTGCTGCACGTGCTGCGCTATCGCCGCGACGCCCTCGACGCGCTCCTCGCGGCG
ATCGACGCGACCGGCTACGGACTCACCTTCGGGCTGCACAGCCGCATCGACGAGACCATCGATCACGTCCTCGGCCGCGT
GCGGGCCGGCAACCGCTACGTGAACCGCAACATCATCGGTGCGGTCGTCGGCGTGCAGCCCTTCGGCGGCTCCGGGCTGT
CGGGGACGGGCCCGAAGGCCGGCGGCCCGCTTTCCCTCGGCCGCCTGCTGCGCCGCGCGCCCGCCGCCGCCCGCGACGGG
CTGGCCGCCGACGATTCGGGTCTGCGTCCCTTCACGGCGTGGCTGCGCTCGCGGCACCGGCACGACCTCGCGGACAGGCT
CGAAGCCGTCCGATATACCGGCCGCGCCGCGATCGCGCTGGCCGGTCCCGTCGGTGAGCGCAACCTGTACGCGCTGCGTC
CCCGCGGGCGCGTCGCGGCCGTCGCCGCCACCGAGACGGCGCTCCTGCTCCAGCTCGGCGCGATCCTCGGCACGGGCAAC
GCGGCCGTCGTCATCGGGCCGGACGGGCGCGATCCGGTCCTGGACGGTCTGCCGGAAGCGTGCGCGGCGCGGGTCGCCCG
GGCGCCGGATCTCGGGCGCGCGGGCGCGATCGTCGGGGTCCTGTTCGCGGGCGGCGCCGACGACCTGCTGGCCCTGAACA
GGGCCGTCGCGGCGCGCGACGGCGCGATCCTGCCGATCCAGGCCCGCTGCCCGGAGGCGCTGGCGGCCGGCGACCTCTAC
GATCCAGCCGGCCTGGTGGAGGAGGTCACCACCACGATCAACACCGCGGCGGCCGGCGGCAATGCCAGCCTGATGAGCGT
CGGGTGA

Upstream 100 bases:

>100_bases
GGATCGCCCCGCGCGTCTCAGGCCTCGACGCGTGTTTTGAACGGTGTAGCGTGAGGCCGCGACGGCGCGGTGTCACCGGG
CCGTGTCCGAGGGGCGGCCC

Downstream 100 bases:

>100_bases
GCCCGCAACTGCCCGGTCAGGCCGACCGGCGCAGATTCCAGAACAGCGGCAGCCCGGTCAGCATGCCTTCGAGGTCCCGC
CGGTAGGCGGTCGGCTGGAA

Product: delta-1-pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1228; Mature: 1227

Protein sequence:

>1228_residues
MSGSGVVDDAAVGASEPFGLFAPALADRSPLRQAVIAACRRPEAGCVAALLAEARLPPDAARRVAEHARRLVESLRRQGR
RGGVEGLIHEYALSSQEGVALMCLAEALLRIPDAATRDALIRDKIAGGDWAAHLGHSPSPFVNAATWGLLVTGKLTATRD
EAGLSAALTRLIARGGEPVIRKGVDLAMRMMGEQFVAGRTIAEALRHAAPLEAKGFTYSYDMLGEAAVTAEDAERFRRAY
AEAIAAIGAASAGRGVLLGPGISIKLSALHPRYVRAQRDRVLAELYPRVLDLARRAMGHGIGLNIDAEEADRLDLSLDIL
ERLAADPELAGWDGLGFVVQAYGKRCPFVIDVLIDLARRCRRRLMVRLVKGAYWDSEIKRAQVDGLSDFPVFTRKVHTDV
SYLACARRLLAAPDAVFPQFATHNAQTLASIVAMAGPDFRLGQYEFQCLHGMGEPLYEAVMADADLQRPCRIYAPVGTHE
TLLAYLVRRLLENGANTSFVNRVADEAVPVADLIADPVAVVEAEPDPGAPHPRIAAPRDLYGPGRANAAGLDLADEAALA
SLWDGLAASGRTAWRAVPSGADAAAADEPVRNPADRRDIVGYDRPATAGTVAIAVARAEAGAAGWAATPATERAACLRRA
ADALEAQMPTLIGLVVREAGKTCASAVAEIREAVDFLRYDAAEAERTLGNAHAPLGPVACIAPWNFPLAIFVGQVAAALA
AGNTVLAKPAEETPLIAAAAVRALHAAGIPAEALHLLPGDGRVGAALVEDPRVQGVMFTGSTAVAKGIQRALAERLNRFD
EPVPFLAETGGQNALVVDSSALAEQVVADVIASAFDSAGQRCSALRILCLQEEIADRTLHMLKGALRELRVGDPRRLAVD
VGPVITAEAADRIIGHVAHMRARGFPVAQFPLPPEADAGTFVPPTLIEIGAVADVEQEVFGPVLHVLRYRRDALDALLAA
IDATGYGLTFGLHSRIDETIDHVLGRVRAGNRYVNRNIIGAVVGVQPFGGSGLSGTGPKAGGPLSLGRLLRRAPAAARDG
LAADDSGLRPFTAWLRSRHRHDLADRLEAVRYTGRAAIALAGPVGERNLYALRPRGRVAAVAATETALLLQLGAILGTGN
AAVVIGPDGRDPVLDGLPEACAARVARAPDLGRAGAIVGVLFAGGADDLLALNRAVAARDGAILPIQARCPEALAAGDLY
DPAGLVEEVTTTINTAAAGGNASLMSVG

Sequences:

>Translated_1228_residues
MSGSGVVDDAAVGASEPFGLFAPALADRSPLRQAVIAACRRPEAGCVAALLAEARLPPDAARRVAEHARRLVESLRRQGR
RGGVEGLIHEYALSSQEGVALMCLAEALLRIPDAATRDALIRDKIAGGDWAAHLGHSPSPFVNAATWGLLVTGKLTATRD
EAGLSAALTRLIARGGEPVIRKGVDLAMRMMGEQFVAGRTIAEALRHAAPLEAKGFTYSYDMLGEAAVTAEDAERFRRAY
AEAIAAIGAASAGRGVLLGPGISIKLSALHPRYVRAQRDRVLAELYPRVLDLARRAMGHGIGLNIDAEEADRLDLSLDIL
ERLAADPELAGWDGLGFVVQAYGKRCPFVIDVLIDLARRCRRRLMVRLVKGAYWDSEIKRAQVDGLSDFPVFTRKVHTDV
SYLACARRLLAAPDAVFPQFATHNAQTLASIVAMAGPDFRLGQYEFQCLHGMGEPLYEAVMADADLQRPCRIYAPVGTHE
TLLAYLVRRLLENGANTSFVNRVADEAVPVADLIADPVAVVEAEPDPGAPHPRIAAPRDLYGPGRANAAGLDLADEAALA
SLWDGLAASGRTAWRAVPSGADAAAADEPVRNPADRRDIVGYDRPATAGTVAIAVARAEAGAAGWAATPATERAACLRRA
ADALEAQMPTLIGLVVREAGKTCASAVAEIREAVDFLRYDAAEAERTLGNAHAPLGPVACIAPWNFPLAIFVGQVAAALA
AGNTVLAKPAEETPLIAAAAVRALHAAGIPAEALHLLPGDGRVGAALVEDPRVQGVMFTGSTAVAKGIQRALAERLNRFD
EPVPFLAETGGQNALVVDSSALAEQVVADVIASAFDSAGQRCSALRILCLQEEIADRTLHMLKGALRELRVGDPRRLAVD
VGPVITAEAADRIIGHVAHMRARGFPVAQFPLPPEADAGTFVPPTLIEIGAVADVEQEVFGPVLHVLRYRRDALDALLAA
IDATGYGLTFGLHSRIDETIDHVLGRVRAGNRYVNRNIIGAVVGVQPFGGSGLSGTGPKAGGPLSLGRLLRRAPAAARDG
LAADDSGLRPFTAWLRSRHRHDLADRLEAVRYTGRAAIALAGPVGERNLYALRPRGRVAAVAATETALLLQLGAILGTGN
AAVVIGPDGRDPVLDGLPEACAARVARAPDLGRAGAIVGVLFAGGADDLLALNRAVAARDGAILPIQARCPEALAAGDLY
DPAGLVEEVTTTINTAAAGGNASLMSVG
>Mature_1227_residues
SGSGVVDDAAVGASEPFGLFAPALADRSPLRQAVIAACRRPEAGCVAALLAEARLPPDAARRVAEHARRLVESLRRQGRR
GGVEGLIHEYALSSQEGVALMCLAEALLRIPDAATRDALIRDKIAGGDWAAHLGHSPSPFVNAATWGLLVTGKLTATRDE
AGLSAALTRLIARGGEPVIRKGVDLAMRMMGEQFVAGRTIAEALRHAAPLEAKGFTYSYDMLGEAAVTAEDAERFRRAYA
EAIAAIGAASAGRGVLLGPGISIKLSALHPRYVRAQRDRVLAELYPRVLDLARRAMGHGIGLNIDAEEADRLDLSLDILE
RLAADPELAGWDGLGFVVQAYGKRCPFVIDVLIDLARRCRRRLMVRLVKGAYWDSEIKRAQVDGLSDFPVFTRKVHTDVS
YLACARRLLAAPDAVFPQFATHNAQTLASIVAMAGPDFRLGQYEFQCLHGMGEPLYEAVMADADLQRPCRIYAPVGTHET
LLAYLVRRLLENGANTSFVNRVADEAVPVADLIADPVAVVEAEPDPGAPHPRIAAPRDLYGPGRANAAGLDLADEAALAS
LWDGLAASGRTAWRAVPSGADAAAADEPVRNPADRRDIVGYDRPATAGTVAIAVARAEAGAAGWAATPATERAACLRRAA
DALEAQMPTLIGLVVREAGKTCASAVAEIREAVDFLRYDAAEAERTLGNAHAPLGPVACIAPWNFPLAIFVGQVAAALAA
GNTVLAKPAEETPLIAAAAVRALHAAGIPAEALHLLPGDGRVGAALVEDPRVQGVMFTGSTAVAKGIQRALAERLNRFDE
PVPFLAETGGQNALVVDSSALAEQVVADVIASAFDSAGQRCSALRILCLQEEIADRTLHMLKGALRELRVGDPRRLAVDV
GPVITAEAADRIIGHVAHMRARGFPVAQFPLPPEADAGTFVPPTLIEIGAVADVEQEVFGPVLHVLRYRRDALDALLAAI
DATGYGLTFGLHSRIDETIDHVLGRVRAGNRYVNRNIIGAVVGVQPFGGSGLSGTGPKAGGPLSLGRLLRRAPAAARDGL
AADDSGLRPFTAWLRSRHRHDLADRLEAVRYTGRAAIALAGPVGERNLYALRPRGRVAAVAATETALLLQLGAILGTGNA
AVVIGPDGRDPVLDGLPEACAARVARAPDLGRAGAIVGVLFAGGADDLLALNRAVAARDGAILPIQARCPEALAAGDLYD
PAGLVEEVTTTINTAAAGGNASLMSVG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=449, Percent_Identity=32.0712694877506, Blast_Score=169, Evalue=2e-41,
Organism=Homo sapiens, GI25777734, Length=449, Percent_Identity=32.0712694877506, Blast_Score=169, Evalue=2e-41,
Organism=Homo sapiens, GI238859541, Length=449, Percent_Identity=32.0712694877506, Blast_Score=168, Evalue=3e-41,
Organism=Homo sapiens, GI188035924, Length=452, Percent_Identity=30.0884955752212, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI310128103, Length=440, Percent_Identity=30.4545454545455, Blast_Score=159, Evalue=2e-38,
Organism=Homo sapiens, GI153266822, Length=472, Percent_Identity=27.9661016949153, Blast_Score=159, Evalue=2e-38,
Organism=Homo sapiens, GI21361176, Length=456, Percent_Identity=29.1666666666667, Blast_Score=158, Evalue=3e-38,
Organism=Homo sapiens, GI310128093, Length=440, Percent_Identity=30.2272727272727, Blast_Score=157, Evalue=4e-38,
Organism=Homo sapiens, GI21614513, Length=436, Percent_Identity=29.1284403669725, Blast_Score=151, Evalue=4e-36,
Organism=Homo sapiens, GI4507229, Length=419, Percent_Identity=30.0715990453461, Blast_Score=149, Evalue=2e-35,
Organism=Homo sapiens, GI12007648, Length=443, Percent_Identity=28.8939051918736, Blast_Score=148, Evalue=3e-35,
Organism=Homo sapiens, GI25777730, Length=418, Percent_Identity=29.6650717703349, Blast_Score=148, Evalue=4e-35,
Organism=Homo sapiens, GI238814322, Length=427, Percent_Identity=27.1662763466042, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI25777732, Length=423, Percent_Identity=28.1323877068558, Blast_Score=143, Evalue=9e-34,
Organism=Homo sapiens, GI25777721, Length=432, Percent_Identity=29.1666666666667, Blast_Score=140, Evalue=6e-33,
Organism=Homo sapiens, GI310128091, Length=389, Percent_Identity=30.5912596401028, Blast_Score=139, Evalue=2e-32,
Organism=Homo sapiens, GI25777724, Length=465, Percent_Identity=27.3118279569892, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI115387104, Length=457, Percent_Identity=25.601750547046, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI25777728, Length=413, Percent_Identity=27.8450363196126, Blast_Score=131, Evalue=4e-30,
Organism=Homo sapiens, GI11095441, Length=402, Percent_Identity=26.6169154228856, Blast_Score=121, Evalue=5e-27,
Organism=Homo sapiens, GI25952152, Length=437, Percent_Identity=27.4599542334096, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI310128087, Length=265, Percent_Identity=32.0754716981132, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI310128089, Length=330, Percent_Identity=29.0909090909091, Blast_Score=106, Evalue=2e-22,
Organism=Homo sapiens, GI206597441, Length=434, Percent_Identity=25.8064516129032, Blast_Score=103, Evalue=1e-21,
Organism=Homo sapiens, GI206597439, Length=434, Percent_Identity=25.8064516129032, Blast_Score=103, Evalue=1e-21,
Organism=Homo sapiens, GI22907049, Length=434, Percent_Identity=25.8064516129032, Blast_Score=103, Evalue=1e-21,
Organism=Homo sapiens, GI25777726, Length=464, Percent_Identity=24.7844827586207, Blast_Score=100, Evalue=9e-21,
Organism=Homo sapiens, GI310128095, Length=311, Percent_Identity=29.2604501607717, Blast_Score=99, Evalue=3e-20,
Organism=Homo sapiens, GI4502043, Length=330, Percent_Identity=27.2727272727273, Blast_Score=96, Evalue=3e-19,
Organism=Homo sapiens, GI238814371, Length=330, Percent_Identity=27.2727272727273, Blast_Score=96, Evalue=3e-19,
Organism=Homo sapiens, GI71773324, Length=330, Percent_Identity=26.969696969697, Blast_Score=95, Evalue=4e-19,
Organism=Homo sapiens, GI310128097, Length=259, Percent_Identity=30.5019305019305, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI310128101, Length=214, Percent_Identity=31.3084112149533, Blast_Score=88, Evalue=6e-17,
Organism=Homo sapiens, GI73695881, Length=330, Percent_Identity=26.3636363636364, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI73695879, Length=330, Percent_Identity=26.3636363636364, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI310128099, Length=211, Percent_Identity=31.7535545023697, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI4557303, Length=331, Percent_Identity=23.8670694864048, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI73466520, Length=331, Percent_Identity=23.8670694864048, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI301500698, Length=430, Percent_Identity=23.7209302325581, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI223972651, Length=428, Percent_Identity=28.0373831775701, Blast_Score=69, Evalue=3e-11,
Organism=Escherichia coli, GI1787250, Length=1255, Percent_Identity=58.2470119521912, Blast_Score=1339, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=450, Percent_Identity=30.4444444444444, Blast_Score=165, Evalue=2e-41,
Organism=Escherichia coli, GI1788042, Length=448, Percent_Identity=32.8125, Blast_Score=162, Evalue=2e-40,
Organism=Escherichia coli, GI87081896, Length=416, Percent_Identity=31.0096153846154, Blast_Score=155, Evalue=1e-38,
Organism=Escherichia coli, GI1787684, Length=431, Percent_Identity=29.0023201856148, Blast_Score=148, Evalue=3e-36,
Organism=Escherichia coli, GI1787715, Length=448, Percent_Identity=32.3660714285714, Blast_Score=144, Evalue=3e-35,
Organism=Escherichia coli, GI1786504, Length=475, Percent_Identity=27.5789473684211, Blast_Score=126, Evalue=8e-30,
Organism=Escherichia coli, GI1787558, Length=426, Percent_Identity=29.5774647887324, Blast_Score=125, Evalue=2e-29,
Organism=Escherichia coli, GI87082295, Length=421, Percent_Identity=27.5534441805226, Blast_Score=119, Evalue=1e-27,
Organism=Escherichia coli, GI87081926, Length=406, Percent_Identity=27.5862068965517, Blast_Score=106, Evalue=7e-24,
Organism=Escherichia coli, GI1787653, Length=272, Percent_Identity=27.2058823529412, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17534447, Length=456, Percent_Identity=32.0175438596491, Blast_Score=176, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI115534176, Length=445, Percent_Identity=31.685393258427, Blast_Score=171, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI115532534, Length=375, Percent_Identity=33.8666666666667, Blast_Score=161, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI25143874, Length=439, Percent_Identity=28.0182232346241, Blast_Score=149, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI25143876, Length=439, Percent_Identity=28.0182232346241, Blast_Score=149, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI25144435, Length=436, Percent_Identity=30.045871559633, Blast_Score=145, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI32564736, Length=414, Percent_Identity=30.1932367149758, Blast_Score=142, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17562198, Length=415, Percent_Identity=29.3975903614458, Blast_Score=140, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI32564151, Length=409, Percent_Identity=30.0733496332518, Blast_Score=135, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71995606, Length=436, Percent_Identity=28.4403669724771, Blast_Score=135, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17534119, Length=453, Percent_Identity=28.2560706401766, Blast_Score=129, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI133930964, Length=419, Percent_Identity=27.2076372315036, Blast_Score=129, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI71995613, Length=393, Percent_Identity=27.9898218829517, Blast_Score=127, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17551164, Length=435, Percent_Identity=27.3563218390805, Blast_Score=122, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71986308, Length=400, Percent_Identity=26.5, Blast_Score=118, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71990744, Length=299, Percent_Identity=29.0969899665552, Blast_Score=100, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI32566756, Length=327, Percent_Identity=25.0764525993884, Blast_Score=87, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI25146391, Length=327, Percent_Identity=25.0764525993884, Blast_Score=87, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI25146394, Length=372, Percent_Identity=23.9247311827957, Blast_Score=87, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17564084, Length=328, Percent_Identity=25.3048780487805, Blast_Score=78, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320917, Length=451, Percent_Identity=31.0421286031042, Blast_Score=176, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6325196, Length=453, Percent_Identity=29.8013245033113, Blast_Score=162, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6324950, Length=414, Percent_Identity=28.5024154589372, Blast_Score=159, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6323822, Length=457, Percent_Identity=30.6345733041575, Blast_Score=149, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6321826, Length=482, Percent_Identity=29.8755186721992, Blast_Score=149, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6323821, Length=458, Percent_Identity=30.3493449781659, Blast_Score=146, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6319478, Length=414, Percent_Identity=27.0531400966184, Blast_Score=130, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6321828, Length=447, Percent_Identity=23.7136465324385, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323757, Length=324, Percent_Identity=25.3086419753086, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281362580, Length=461, Percent_Identity=30.3687635574837, Blast_Score=170, Evalue=5e-42,
Organism=Drosophila melanogaster, GI62472918, Length=461, Percent_Identity=30.3687635574837, Blast_Score=170, Evalue=5e-42,
Organism=Drosophila melanogaster, GI62472926, Length=461, Percent_Identity=30.3687635574837, Blast_Score=170, Evalue=5e-42,
Organism=Drosophila melanogaster, GI62472936, Length=461, Percent_Identity=30.3687635574837, Blast_Score=170, Evalue=5e-42,
Organism=Drosophila melanogaster, GI21356737, Length=461, Percent_Identity=30.3687635574837, Blast_Score=170, Evalue=5e-42,
Organism=Drosophila melanogaster, GI20129399, Length=419, Percent_Identity=30.0715990453461, Blast_Score=167, Evalue=4e-41,
Organism=Drosophila melanogaster, GI24668425, Length=517, Percent_Identity=25.9187620889749, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24668417, Length=517, Percent_Identity=25.9187620889749, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24668413, Length=517, Percent_Identity=25.9187620889749, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI28571798, Length=473, Percent_Identity=26.0042283298097, Blast_Score=138, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28571796, Length=473, Percent_Identity=26.0042283298097, Blast_Score=138, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28571794, Length=473, Percent_Identity=26.0042283298097, Blast_Score=138, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28571802, Length=473, Percent_Identity=26.0042283298097, Blast_Score=138, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28571800, Length=473, Percent_Identity=26.0042283298097, Blast_Score=138, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28571806, Length=473, Percent_Identity=26.0042283298097, Blast_Score=138, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28574525, Length=445, Percent_Identity=27.1910112359551, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24666674, Length=424, Percent_Identity=27.8301886792453, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24650465, Length=453, Percent_Identity=26.7108167770419, Blast_Score=132, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24585660, Length=440, Percent_Identity=25.6818181818182, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281360299, Length=335, Percent_Identity=28.3582089552239, Blast_Score=100, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281360297, Length=335, Percent_Identity=28.3582089552239, Blast_Score=100, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281360295, Length=335, Percent_Identity=28.3582089552239, Blast_Score=100, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24586250, Length=335, Percent_Identity=28.3582089552239, Blast_Score=100, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281360301, Length=335, Percent_Identity=28.3582089552239, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45552499, Length=335, Percent_Identity=28.0597014925373, Blast_Score=98, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281360303, Length=335, Percent_Identity=28.0597014925373, Blast_Score=97, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24638876, Length=401, Percent_Identity=24.9376558603491, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24638878, Length=401, Percent_Identity=24.9376558603491, Blast_Score=92, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 128662; Mature: 128530

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSGVVDDAAVGASEPFGLFAPALADRSPLRQAVIAACRRPEAGCVAALLAEARLPPDA
CCCCCCCCHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHH
ARRVAEHARRLVESLRRQGRRGGVEGLIHEYALSSQEGVALMCLAEALLRIPDAATRDAL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHH
IRDKIAGGDWAAHLGHSPSPFVNAATWGLLVTGKLTATRDEAGLSAALTRLIARGGEPVI
HHHHCCCCCHHHHCCCCCCCCCCHHHEEEEEECCEECCCCHHHHHHHHHHHHHCCCCHHH
RKGVDLAMRMMGEQFVAGRTIAEALRHAAPLEAKGFTYSYDMLGEAAVTAEDAERFRRAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHCCHHHHHHHHHHHHHHH
AEAIAAIGAASAGRGVLLGPGISIKLSALHPRYVRAQRDRVLAELYPRVLDLARRAMGHG
HHHHHHHHCCCCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IGLNIDAEEADRLDLSLDILERLAADPELAGWDGLGFVVQAYGKRCPFVIDVLIDLARRC
CCCCCCCCHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
RRRLMVRLVKGAYWDSEIKRAQVDGLSDFPVFTRKVHTDVSYLACARRLLAAPDAVFPQF
HHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCHH
ATHNAQTLASIVAMAGPDFRLGQYEFQCLHGMGEPLYEAVMADADLQRPCRIYAPVGTHE
HCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEECCCCHH
TLLAYLVRRLLENGANTSFVNRVADEAVPVADLIADPVAVVEAEPDPGAPHPRIAAPRDL
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHCCEEEEECCCCCCCCCCCCCCCCCC
YGPGRANAAGLDLADEAALASLWDGLAASGRTAWRAVPSGADAAAADEPVRNPADRRDIV
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHEECCCCCCCCCCCCCCCCCCCCCCCC
GYDRPATAGTVAIAVARAEAGAAGWAATPATERAACLRRAADALEAQMPTLIGLVVREAG
CCCCCCCCCCEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTCASAVAEIREAVDFLRYDAAEAERTLGNAHAPLGPVACIAPWNFPLAIFVGQVAAALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHH
AGNTVLAKPAEETPLIAAAAVRALHAAGIPAEALHLLPGDGRVGAALVEDPRVQGVMFTG
CCCEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHEECCCCCCCCHHEECCCCCCEEEEEC
STAVAKGIQRALAERLNRFDEPVPFLAETGGQNALVVDSSALAEQVVADVIASAFDSAGQ
CHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHH
RCSALRILCLQEEIADRTLHMLKGALRELRVGDPRRLAVDVGPVITAEAADRIIGHVAHM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEHHHHHHHHHHHHHH
RARGFPVAQFPLPPEADAGTFVPPTLIEIGAVADVEQEVFGPVLHVLRYRRDALDALLAA
HHCCCCEEECCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDATGYGLTFGLHSRIDETIDHVLGRVRAGNRYVNRNIIGAVVGVQPFGGSGLSGTGPKA
HHCCCCCEEHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEHEEECCCCCCCCCCCCCCCC
GGPLSLGRLLRRAPAAARDGLAADDSGLRPFTAWLRSRHRHDLADRLEAVRYTGRAAIAL
CCCHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
AGPVGERNLYALRPRGRVAAVAATETALLLQLGAILGTGNAAVVIGPDGRDPVLDGLPEA
ECCCCCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHCCHHH
CAARVARAPDLGRAGAIVGVLFAGGADDLLALNRAVAARDGAILPIQARCPEALAAGDLY
HHHHHHCCCCCCCCHHHHHHEECCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHCCCCC
DPAGLVEEVTTTINTAAAGGNASLMSVG
CHHHHHHHHHHHHHHHCCCCCCEEEECC
>Mature Secondary Structure 
SGSGVVDDAAVGASEPFGLFAPALADRSPLRQAVIAACRRPEAGCVAALLAEARLPPDA
CCCCCCCHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHH
ARRVAEHARRLVESLRRQGRRGGVEGLIHEYALSSQEGVALMCLAEALLRIPDAATRDAL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHH
IRDKIAGGDWAAHLGHSPSPFVNAATWGLLVTGKLTATRDEAGLSAALTRLIARGGEPVI
HHHHCCCCCHHHHCCCCCCCCCCHHHEEEEEECCEECCCCHHHHHHHHHHHHHCCCCHHH
RKGVDLAMRMMGEQFVAGRTIAEALRHAAPLEAKGFTYSYDMLGEAAVTAEDAERFRRAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHCCHHHHHHHHHHHHHHH
AEAIAAIGAASAGRGVLLGPGISIKLSALHPRYVRAQRDRVLAELYPRVLDLARRAMGHG
HHHHHHHHCCCCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IGLNIDAEEADRLDLSLDILERLAADPELAGWDGLGFVVQAYGKRCPFVIDVLIDLARRC
CCCCCCCCHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
RRRLMVRLVKGAYWDSEIKRAQVDGLSDFPVFTRKVHTDVSYLACARRLLAAPDAVFPQF
HHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCHH
ATHNAQTLASIVAMAGPDFRLGQYEFQCLHGMGEPLYEAVMADADLQRPCRIYAPVGTHE
HCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEECCCCHH
TLLAYLVRRLLENGANTSFVNRVADEAVPVADLIADPVAVVEAEPDPGAPHPRIAAPRDL
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHCCEEEEECCCCCCCCCCCCCCCCCC
YGPGRANAAGLDLADEAALASLWDGLAASGRTAWRAVPSGADAAAADEPVRNPADRRDIV
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHEECCCCCCCCCCCCCCCCCCCCCCCC
GYDRPATAGTVAIAVARAEAGAAGWAATPATERAACLRRAADALEAQMPTLIGLVVREAG
CCCCCCCCCCEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTCASAVAEIREAVDFLRYDAAEAERTLGNAHAPLGPVACIAPWNFPLAIFVGQVAAALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHH
AGNTVLAKPAEETPLIAAAAVRALHAAGIPAEALHLLPGDGRVGAALVEDPRVQGVMFTG
CCCEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHEECCCCCCCCHHEECCCCCCEEEEEC
STAVAKGIQRALAERLNRFDEPVPFLAETGGQNALVVDSSALAEQVVADVIASAFDSAGQ
CHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHH
RCSALRILCLQEEIADRTLHMLKGALRELRVGDPRRLAVDVGPVITAEAADRIIGHVAHM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEHHHHHHHHHHHHHH
RARGFPVAQFPLPPEADAGTFVPPTLIEIGAVADVEQEVFGPVLHVLRYRRDALDALLAA
HHCCCCEEECCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDATGYGLTFGLHSRIDETIDHVLGRVRAGNRYVNRNIIGAVVGVQPFGGSGLSGTGPKA
HHCCCCCEEHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEHEEECCCCCCCCCCCCCCCC
GGPLSLGRLLRRAPAAARDGLAADDSGLRPFTAWLRSRHRHDLADRLEAVRYTGRAAIAL
CCCHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
AGPVGERNLYALRPRGRVAAVAATETALLLQLGAILGTGNAAVVIGPDGRDPVLDGLPEA
ECCCCCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHCCHHH
CAARVARAPDLGRAGAIVGVLFAGGADDLLALNRAVAARDGAILPIQARCPEALAAGDLY
HHHHHHCCCCCCCCHHHHHHEECCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHCCCCC
DPAGLVEEVTTTINTAAAGGNASLMSVG
CHHHHHHHHHHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]