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The map label for this gene is glpX [H]

Identifier: 170749325

GI number: 170749325

Start: 3076620

End: 3077603

Strand: Reverse

Name: glpX [H]

Synonym: Mrad2831_2918

Alternate gene names: 170749325

Gene position: 3077603-3076620 (Counterclockwise)

Preceding gene: 170749326

Following gene: 170749323

Centisome position: 50.64

GC content: 73.27

Gene sequence:

>984_bases
ATGGAAGAGGCCCCCAAGCCGGCATCGCGCGGCGTCCCGCGCACGCTCGCCCTCGAACTGGCCCGCGTGACGGAGCGTGC
CGCCATCGCCGCCGCCCGATTGCGCGGCCAGGGCGACGAGAAGGCGGCCGACCAGGCGGCGGTCGACGCGATGCGCGACG
AACTCAACGGCCTGCCGATCCGCGGCACCGTGGTGATCGGGGAGGGGGAGCGCGATCAGGCGCCGATGCTGTTCATCGGC
GAGCAGCTCGGTCTCGGGGAAGGGCCCGAGGTCGACATCGCGGTCGATCCGCTGGAGGGCACGACCCTCTGCGCCAAGGA
CATGCCCGGCGCCATCGCGGTCATGGCCATGGCGGAGCGCGGCTCGCTCCTCGCCGCGCCCGACGTCTACATGCAGAAGA
TCGCCATCGGGCCCGGCTACCCGCCCGGGCTCGTCGATCTCGACGCCAGCCCGACCGACAACATCCTGGCGCTGGCCAGG
GCCAAGGGCGTCGATCCGAAGCAGATCACCGCCCTGATCCTCGACCGGCCGCGGCACGCGGCCCTCGTGGCCGAGGTGCG
GGCGGCCGGCGCGGCGGTGCGCCTGATCTCGGACGGCGACATCGCCGGGATCATCTTCACGGCGAGCCCCGAGGAGACGG
GCATCGACCTGTATCTCGGGACCGGCGCGGCGCCCGAGGGCGTGCTGGCGGCCGCCGCGATGCGCTGCATCGGCGGCCAG
ATGCAGGGGCGCCTGATCCTGGATACCCCGGACCGGCGGCGCCGGGCCGCCGAGATGGGCATCGAGAATCTCGACCGGAA
ATACGACCTGACCGACCTCGCGAGCGGTGACGTCATCGTGGCCGCCACGGGCATCACCGACGGGGCGCTCCTGCGCGGCG
TGCGCTTCAGGCCGGACCGGATCCAGACCGAGACCCTGGTCTACCGGTCCGAGGCCGGGACGGTGCGGCGGATCCTCGGC
GAGCACCGCCGCGGGCTGACCTGA

Upstream 100 bases:

>100_bases
TGGGCCTTAGCGAACCGGCGTATACGCTGCGCGGCCGTCATCCGACGGTATCCATCCGGGATCCGACCCCAAGATCGGAC
CCGGCCAGAGGCAGGAAACC

Downstream 100 bases:

>100_bases
TCCCGCGGGCCGCCGGTCCGCGACCGGCGGCGTTCAGTCCGACGGTTCGGCCCGGCTTCAGTTCAGCACTACCACCTTGC
TGCCGACGGGGACGCGGCTG

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MEEAPKPASRGVPRTLALELARVTERAAIAAARLRGQGDEKAADQAAVDAMRDELNGLPIRGTVVIGEGERDQAPMLFIG
EQLGLGEGPEVDIAVDPLEGTTLCAKDMPGAIAVMAMAERGSLLAAPDVYMQKIAIGPGYPPGLVDLDASPTDNILALAR
AKGVDPKQITALILDRPRHAALVAEVRAAGAAVRLISDGDIAGIIFTASPEETGIDLYLGTGAAPEGVLAAAAMRCIGGQ
MQGRLILDTPDRRRRAAEMGIENLDRKYDLTDLASGDVIVAATGITDGALLRGVRFRPDRIQTETLVYRSEAGTVRRILG
EHRRGLT

Sequences:

>Translated_327_residues
MEEAPKPASRGVPRTLALELARVTERAAIAAARLRGQGDEKAADQAAVDAMRDELNGLPIRGTVVIGEGERDQAPMLFIG
EQLGLGEGPEVDIAVDPLEGTTLCAKDMPGAIAVMAMAERGSLLAAPDVYMQKIAIGPGYPPGLVDLDASPTDNILALAR
AKGVDPKQITALILDRPRHAALVAEVRAAGAAVRLISDGDIAGIIFTASPEETGIDLYLGTGAAPEGVLAAAAMRCIGGQ
MQGRLILDTPDRRRRAAEMGIENLDRKYDLTDLASGDVIVAATGITDGALLRGVRFRPDRIQTETLVYRSEAGTVRRILG
EHRRGLT
>Mature_327_residues
MEEAPKPASRGVPRTLALELARVTERAAIAAARLRGQGDEKAADQAAVDAMRDELNGLPIRGTVVIGEGERDQAPMLFIG
EQLGLGEGPEVDIAVDPLEGTTLCAKDMPGAIAVMAMAERGSLLAAPDVYMQKIAIGPGYPPGLVDLDASPTDNILALAR
AKGVDPKQITALILDRPRHAALVAEVRAAGAAVRLISDGDIAGIIFTASPEETGIDLYLGTGAAPEGVLAAAAMRCIGGQ
MQGRLILDTPDRRRRAAEMGIENLDRKYDLTDLASGDVIVAATGITDGALLRGVRFRPDRIQTETLVYRSEAGTVRRILG
EHRRGLT

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtilis [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=323, Percent_Identity=45.2012383900929, Blast_Score=242, Evalue=3e-65,
Organism=Escherichia coli, GI1789298, Length=307, Percent_Identity=42.3452768729642, Blast_Score=211, Evalue=4e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 34407; Mature: 34407

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEAPKPASRGVPRTLALELARVTERAAIAAARLRGQGDEKAADQAAVDAMRDELNGLPI
CCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCE
RGTVVIGEGERDQAPMLFIGEQLGLGEGPEVDIAVDPLEGTTLCAKDMPGAIAVMAMAER
EEEEEEECCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCEEECCCCCCCEEEEEECCC
GSLLAAPDVYMQKIAIGPGYPPGLVDLDASPTDNILALARAKGVDPKQITALILDRPRHA
CCEEECCHHHHHHEECCCCCCCCEEECCCCCCCCEEEEHHHCCCCHHHEEEEEECCCCHH
ALVAEVRAAGAAVRLISDGDIAGIIFTASPEETGIDLYLGTGAAPEGVLAAAAMRCIGGQ
HHHHHHHHCCEEEEEEECCCEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCC
MQGRLILDTPDRRRRAAEMGIENLDRKYDLTDLASGDVIVAATGITDGALLRGVRFRPDR
CCCEEEEECCHHHHHHHHHCHHHCCCCCCHHHCCCCCEEEEECCCCCHHHHCCCCCCCCC
IQTETLVYRSEAGTVRRILGEHRRGLT
CCEEEEEEECCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MEEAPKPASRGVPRTLALELARVTERAAIAAARLRGQGDEKAADQAAVDAMRDELNGLPI
CCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCE
RGTVVIGEGERDQAPMLFIGEQLGLGEGPEVDIAVDPLEGTTLCAKDMPGAIAVMAMAER
EEEEEEECCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCEEECCCCCCCEEEEEECCC
GSLLAAPDVYMQKIAIGPGYPPGLVDLDASPTDNILALARAKGVDPKQITALILDRPRHA
CCEEECCHHHHHHEECCCCCCCCEEECCCCCCCCEEEEHHHCCCCHHHEEEEEECCCCHH
ALVAEVRAAGAAVRLISDGDIAGIIFTASPEETGIDLYLGTGAAPEGVLAAAAMRCIGGQ
HHHHHHHHCCEEEEEEECCCEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCC
MQGRLILDTPDRRRRAAEMGIENLDRKYDLTDLASGDVIVAATGITDGALLRGVRFRPDR
CCCEEEEECCHHHHHHHHHCHHHCCCCCCHHHCCCCCEEEEECCCCCHHHHCCCCCCCCC
IQTETLVYRSEAGTVRRILGEHRRGLT
CCEEEEEEECCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]