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The map label for this gene is ribBA [H]

Identifier: 170749162

GI number: 170749162

Start: 2892368

End: 2893444

Strand: Reverse

Name: ribBA [H]

Synonym: Mrad2831_2755

Alternate gene names: 170749162

Gene position: 2893444-2892368 (Counterclockwise)

Preceding gene: 170749163

Following gene: 170749159

Centisome position: 47.61

GC content: 70.1

Gene sequence:

>1077_bases
GTGCCCCACTGCTCCGTCACAGAGGCCATCGCGGCCTTCGCCCGCGGCGAGATCGTGGTCGTCACCGACGACGACGACCG
CGAGAACGAGGGCGACCTCGTCGTCGCAGCCTCGCTCTGCACGCCGGAGAAGATGGCGTTCATCATCCGCAACACCTGCG
GCATCGTCTGCGCGCCGCTCACGCAGAGCGAGGCGCGGCGGCTCCACCTCGCGCCCATGGTGGCGTCGAACGACGCCCCC
CTGGGCACGGCCTTCACCGTCACGGTCGACGTCAAGCACGGCCTGACGACGGGGATCTCGGCGGAGCAGCGCTGCAACAC
GGTGCGGGCGCTCGCCAACGGCAACATGGGCGCGGGCGACTTCGTGCGGCCAGGCCACGTCTTCCCGCTCATCGCCCGCG
ACGGCGGCGTGCTCATGCGCTCGGGCCACACGGAAGCGGCGGTCGACCTGTGCCGCCTCGCCGAGCTGCCGCCCGTCGGC
GTGATCTGCGAACTCGCCAACGACGACGGTACGGTGATGAAGGGGCCGCAGATCGAGGCCTTCGCCGAGAAGCACGGCCT
CAAGCAGGTCTCGGTGGCCGACCTCATCGCCTACCGACAGGCGCGCGACCGGCTGGTGGAGCGGGTCGGCCACTTCACGG
TCCGATCGAACCACGGCGACGTGAACGCCTACGTGTTCTCGACGCCCTTCGAGTCGATCCAGCAATTCGCCTTCGTGATG
GGCGAGATCGGCGACGGTCGGGACGTGCTGGTGCGCCTGCACCGCTCCAACGTCGCCGCCGACGTGATCGGCGGCGGCAA
GCAGATCGACGCCGTGCTGAAGCGCTTCGCGGCCGCCGGCCGCGGCGTGCTGGTCTATCTCCGGGACGGAACCGCGGGCG
TGCCGGTCAAGAACGTCACCGAGGAGGGGACGGAGGCGCTGCGGGCGCGGCAATGGCGCGAGATCGGGCTCGGCGCCCAG
ATTCTGCGCGATCTGGGTGTTGTCTCCATCCGCAACCTCGCGACCTCGTCGCGCTCCTATGTCGGCCTCTCGGGCTTCGG
CATCGAGCTCCTGGGCGACGAGCCTCTCGAAGGCTGA

Upstream 100 bases:

>100_bases
GTAGACGCACAAGTGTTTTTCTTTGATGCAGATCCCGTATTTGCTTTTGCATCAGAGTACCGTGCGCAAATATCGTCCCT
TGCTTACCGGTAGTATCTCC

Downstream 100 bases:

>100_bases
GGCAGGACCGGGACGCCCGGTCAAGCGCGGCGCAGGACGGTCCAGACCGCGGCGCCGGCCATGATGGCGGCGGCACCGCG
GTTCAGCCGCGTGCGGAAAG

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: 3,4-dihydroxy-2-butanone 4-phosphate synthase; DHBP synthase; GTP cyclohydrolase-2; GTP cyclohydrolase II [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MPHCSVTEAIAAFARGEIVVVTDDDDRENEGDLVVAASLCTPEKMAFIIRNTCGIVCAPLTQSEARRLHLAPMVASNDAP
LGTAFTVTVDVKHGLTTGISAEQRCNTVRALANGNMGAGDFVRPGHVFPLIARDGGVLMRSGHTEAAVDLCRLAELPPVG
VICELANDDGTVMKGPQIEAFAEKHGLKQVSVADLIAYRQARDRLVERVGHFTVRSNHGDVNAYVFSTPFESIQQFAFVM
GEIGDGRDVLVRLHRSNVAADVIGGGKQIDAVLKRFAAAGRGVLVYLRDGTAGVPVKNVTEEGTEALRARQWREIGLGAQ
ILRDLGVVSIRNLATSSRSYVGLSGFGIELLGDEPLEG

Sequences:

>Translated_358_residues
MPHCSVTEAIAAFARGEIVVVTDDDDRENEGDLVVAASLCTPEKMAFIIRNTCGIVCAPLTQSEARRLHLAPMVASNDAP
LGTAFTVTVDVKHGLTTGISAEQRCNTVRALANGNMGAGDFVRPGHVFPLIARDGGVLMRSGHTEAAVDLCRLAELPPVG
VICELANDDGTVMKGPQIEAFAEKHGLKQVSVADLIAYRQARDRLVERVGHFTVRSNHGDVNAYVFSTPFESIQQFAFVM
GEIGDGRDVLVRLHRSNVAADVIGGGKQIDAVLKRFAAAGRGVLVYLRDGTAGVPVKNVTEEGTEALRARQWREIGLGAQ
ILRDLGVVSIRNLATSSRSYVGLSGFGIELLGDEPLEG
>Mature_357_residues
PHCSVTEAIAAFARGEIVVVTDDDDRENEGDLVVAASLCTPEKMAFIIRNTCGIVCAPLTQSEARRLHLAPMVASNDAPL
GTAFTVTVDVKHGLTTGISAEQRCNTVRALANGNMGAGDFVRPGHVFPLIARDGGVLMRSGHTEAAVDLCRLAELPPVGV
ICELANDDGTVMKGPQIEAFAEKHGLKQVSVADLIAYRQARDRLVERVGHFTVRSNHGDVNAYVFSTPFESIQQFAFVMG
EIGDGRDVLVRLHRSNVAADVIGGGKQIDAVLKRFAAAGRGVLVYLRDGTAGVPVKNVTEEGTEALRARQWREIGLGAQI
LRDLGVVSIRNLATSSRSYVGLSGFGIELLGDEPLEG

Specific function: Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=203, Percent_Identity=49.2610837438424, Blast_Score=196, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6320695, Length=202, Percent_Identity=48.019801980198, Blast_Score=183, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12; =3.5.4.25 [H]

Molecular weight: Translated: 38165; Mature: 38034

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHCSVTEAIAAFARGEIVVVTDDDDRENEGDLVVAASLCTPEKMAFIIRNTCGIVCAPL
CCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHEECCCCEEEECC
TQSEARRLHLAPMVASNDAPLGTAFTVTVDVKHGLTTGISAEQRCNTVRALANGNMGAGD
CHHHCCEEEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCC
FVRPGHVFPLIARDGGVLMRSGHTEAAVDLCRLAELPPVGVICELANDDGTVMKGPQIEA
CCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCHHH
FAEKHGLKQVSVADLIAYRQARDRLVERVGHFTVRSNHGDVNAYVFSTPFESIQQFAFVM
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEEEECCHHHHHHHHHHH
GEIGDGRDVLVRLHRSNVAADVIGGGKQIDAVLKRFAAAGRGVLVYLRDGTAGVPVKNVT
HCCCCCCEEEEEEECCCCEEECCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCH
EEGTEALRARQWREIGLGAQILRDLGVVSIRNLATSSRSYVGLSGFGIELLGDEPLEG
HHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHCCCCCEEEECCCCEEEECCCCCCC
>Mature Secondary Structure 
PHCSVTEAIAAFARGEIVVVTDDDDRENEGDLVVAASLCTPEKMAFIIRNTCGIVCAPL
CCCHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHEECCCCEEEECC
TQSEARRLHLAPMVASNDAPLGTAFTVTVDVKHGLTTGISAEQRCNTVRALANGNMGAGD
CHHHCCEEEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCC
FVRPGHVFPLIARDGGVLMRSGHTEAAVDLCRLAELPPVGVICELANDDGTVMKGPQIEA
CCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCHHH
FAEKHGLKQVSVADLIAYRQARDRLVERVGHFTVRSNHGDVNAYVFSTPFESIQQFAFVM
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEEEECCHHHHHHHHHHH
GEIGDGRDVLVRLHRSNVAADVIGGGKQIDAVLKRFAAAGRGVLVYLRDGTAGVPVKNVT
HCCCCCCEEEEEEECCCCEEECCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCH
EEGTEALRARQWREIGLGAQILRDLGVVSIRNLATSSRSYVGLSGFGIELLGDEPLEG
HHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHCCCCCEEEECCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA