Click here to switch to the map view.

The map label for this gene is fabA [H]

Identifier: 170749092

GI number: 170749092

Start: 2828568

End: 2829104

Strand: Reverse

Name: fabA [H]

Synonym: Mrad2831_2685

Alternate gene names: 170749092

Gene position: 2829104-2828568 (Counterclockwise)

Preceding gene: 170749094

Following gene: 170749091

Centisome position: 46.55

GC content: 68.53

Gene sequence:

>537_bases
ATGCCGCCAGACGCCGAGACACAAGCGCAGGGTGCGAACCGCCGGTCGCACTATTCCTACGAGGATCTTCTGGCCTGCGG
GCGCGGCGAACTCTTCGGACCCGGCAACGCGCAATTGCCGCTGCCGCCGATGCTGATGTTCGACCGGATCACGTCCATCG
GGACCGAGGGCGGCGCCCACGGCAAGGGGCACGTGACGGCCGAGCTCGATATCCGGCCGGACCTCTGGTTCTTCCCCTGC
CATTTCCAGGGCGATCCGGTCATGCCGGGTTGCCTGGGGCTCGACGCCCTGTGGCAGATGCTGGGCTTCCATCTCGGCTG
GCTCGGCTCGCCGGGCCGCGGCCGCGCCCTCGGCGTGGGCGAGGTGAAGCTCGCCGGCCAGGTGCTGCCGACGATCAAGA
AGGTCGTCTACAACGTCGACGTGAAGCGGGTCCGTCAGGGCAAGCTCGTGCTCGGCATCGGCGACGGCTGGCTCGAGGCG
GACGGCGAGCGCGTCTATCAGGTCCAGGACATGCGGGTCGGCCTGTTCCAGAGTTGA

Upstream 100 bases:

>100_bases
AAGGCGCGGCGCCCCGTGCTAACCCGCGCGCCAGCCGACGGGCCGAGTATAGTCGCCCGCGACGCGAAGATCGCGCCCAT
CCGAGGAAACAGCCAACGCA

Downstream 100 bases:

>100_bases
GCCGCGTCGCCGCGCGCCCGGCTCGCGGCTCGGCCGCAACGCCGGACGTTCTCGGCGGTTGAGATTGTGTCCGCGTCACC
TTAGCTGACCGTGACGCGGC

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase [H]

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MPPDAETQAQGANRRSHYSYEDLLACGRGELFGPGNAQLPLPPMLMFDRITSIGTEGGAHGKGHVTAELDIRPDLWFFPC
HFQGDPVMPGCLGLDALWQMLGFHLGWLGSPGRGRALGVGEVKLAGQVLPTIKKVVYNVDVKRVRQGKLVLGIGDGWLEA
DGERVYQVQDMRVGLFQS

Sequences:

>Translated_178_residues
MPPDAETQAQGANRRSHYSYEDLLACGRGELFGPGNAQLPLPPMLMFDRITSIGTEGGAHGKGHVTAELDIRPDLWFFPC
HFQGDPVMPGCLGLDALWQMLGFHLGWLGSPGRGRALGVGEVKLAGQVLPTIKKVVYNVDVKRVRQGKLVLGIGDGWLEA
DGERVYQVQDMRVGLFQS
>Mature_177_residues
PPDAETQAQGANRRSHYSYEDLLACGRGELFGPGNAQLPLPPMLMFDRITSIGTEGGAHGKGHVTAELDIRPDLWFFPCH
FQGDPVMPGCLGLDALWQMLGFHLGWLGSPGRGRALGVGEVKLAGQVLPTIKKVVYNVDVKRVRQGKLVLGIGDGWLEAD
GERVYQVQDMRVGLFQS

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787187, Length=167, Percent_Identity=59.8802395209581, Blast_Score=215, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: =4.2.1.60 [H]

Molecular weight: Translated: 19397; Mature: 19265

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPDAETQAQGANRRSHYSYEDLLACGRGELFGPGNAQLPLPPMLMFDRITSIGTEGGAH
CCCCCCCHHCCCCCCCCCCHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHCCCCCCCC
GKGHVTAELDIRPDLWFFPCHFQGDPVMPGCLGLDALWQMLGFHLGWLGSPGRGRALGVG
CCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEECCC
EVKLAGQVLPTIKKVVYNVDVKRVRQGKLVLGIGDGWLEADGERVYQVQDMRVGLFQS
CEEEHHHHHHHHHHHHHCCCHHHHCCCCEEEEECCCEEECCCCEEEEEECCEECCCCC
>Mature Secondary Structure 
PPDAETQAQGANRRSHYSYEDLLACGRGELFGPGNAQLPLPPMLMFDRITSIGTEGGAH
CCCCCCHHCCCCCCCCCCHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHCCCCCCCC
GKGHVTAELDIRPDLWFFPCHFQGDPVMPGCLGLDALWQMLGFHLGWLGSPGRGRALGVG
CCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEECCC
EVKLAGQVLPTIKKVVYNVDVKRVRQGKLVLGIGDGWLEADGERVYQVQDMRVGLFQS
CEEEHHHHHHHHHHHHHCCCHHHHCCCCEEEEECCCEEECCCCEEEEEECCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA