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The map label for this gene is comF [H]

Identifier: 170749082

GI number: 170749082

Start: 2821356

End: 2822117

Strand: Reverse

Name: comF [H]

Synonym: Mrad2831_2675

Alternate gene names: 170749082

Gene position: 2822117-2821356 (Counterclockwise)

Preceding gene: 170749083

Following gene: 170749080

Centisome position: 46.43

GC content: 75.33

Gene sequence:

>762_bases
ATGACGGCCCTCCAGGCCGTCGCCACGGCCCTGCGCGGTCTGCCGCGCGGGGTCGTCTCTCTGGTCTACCCGCCCACCTG
CGCGGGCTGCGGCAGCGCCACCGCCGATCCGGGCGCCTTCTGCCCGTCGTGCTGGTCGAGCCTGCGCCTGATCGAGGAAC
CGGTCTGCCAGCGCTACGGCACGCCCTTCGCGCTCGATCTCGGGGTCGGCCCGCTGGTGTCGCCCCGGGCGATCGCGGAA
CCGCCGGTCTTCGGCCGCGCCCGGGCGGTCGCCCTCTACGATGCCGTGGCGCGACGGATCGTCCATCGCCTGAAATACGA
GGACCGGCTCGATCTCGCCGGCGTCATGGCGCGGATGATGGCCGCGAGCGGCCGGACCCTGATCGCCGAGGCCGAGTGCC
TCGTTCCGGTGCCGCTCCATCGCGGTCGCCTGTGGCGGCGGCGCTTCAACCAGTCGGCCCTGCTCGCGCGGGCGATCGCC
GCTTCGGCGGGACGGCCGTGCGTCGCCACCGCCCTGGTGCGCGTGCGCGCCACGCGATCCCAGGTCGGCCTGAGCCGCGC
GGCGCGGGCCGAGAACCTGAGCGGTGCCTTCCGGGTGACGGCCGCCGAACAGCACCGCATCCGCGGACGCCGGGTTCTCC
TCGTCGACGACGTCATGACCACCGGCGCCACCGGCAACGCGGCCGCACGGGCGCTCCTGCGCGGCGGGGCGACGTCCGTG
GACCTCCTGACCTTCGCCCTCGTCGGCGACCCCGCCGGCTGA

Upstream 100 bases:

>100_bases
GCCAACGCGCGCGACCGTCAGGTCGAGCAGCAGCAGATGGCGCCGCAGGCGCGGCCCGTCTCGGCCCAGTAGGCGGGAAC
TCCGGTCGCGCGTTGCGCGC

Downstream 100 bases:

>100_bases
GGGGCCGGCCGCCGCGGGCCCGGCACCGGCGACCGGCCTCCTCGCCCGGCCGCGACGCCCGGCCTCAGCGCCCGGCCTGC
ATCCGCTCCGGAAAGCTCGC

Product: competence protein F

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTALQAVATALRGLPRGVVSLVYPPTCAGCGSATADPGAFCPSCWSSLRLIEEPVCQRYGTPFALDLGVGPLVSPRAIAE
PPVFGRARAVALYDAVARRIVHRLKYEDRLDLAGVMARMMAASGRTLIAEAECLVPVPLHRGRLWRRRFNQSALLARAIA
ASAGRPCVATALVRVRATRSQVGLSRAARAENLSGAFRVTAAEQHRIRGRRVLLVDDVMTTGATGNAAARALLRGGATSV
DLLTFALVGDPAG

Sequences:

>Translated_253_residues
MTALQAVATALRGLPRGVVSLVYPPTCAGCGSATADPGAFCPSCWSSLRLIEEPVCQRYGTPFALDLGVGPLVSPRAIAE
PPVFGRARAVALYDAVARRIVHRLKYEDRLDLAGVMARMMAASGRTLIAEAECLVPVPLHRGRLWRRRFNQSALLARAIA
ASAGRPCVATALVRVRATRSQVGLSRAARAENLSGAFRVTAAEQHRIRGRRVLLVDDVMTTGATGNAAARALLRGGATSV
DLLTFALVGDPAG
>Mature_252_residues
TALQAVATALRGLPRGVVSLVYPPTCAGCGSATADPGAFCPSCWSSLRLIEEPVCQRYGTPFALDLGVGPLVSPRAIAEP
PVFGRARAVALYDAVARRIVHRLKYEDRLDLAGVMARMMAASGRTLIAEAECLVPVPLHRGRLWRRRFNQSALLARAIAA
SAGRPCVATALVRVRATRSQVGLSRAARAENLSGAFRVTAAEQHRIRGRRVLLVDDVMTTGATGNAAARALLRGGATSVD
LLTFALVGDPAG

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=225, Percent_Identity=30.6666666666667, Blast_Score=84, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 26691; Mature: 26560

Theoretical pI: Translated: 11.56; Mature: 11.56

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALQAVATALRGLPRGVVSLVYPPTCAGCGSATADPGAFCPSCWSSLRLIEEPVCQRYG
CHHHHHHHHHHHCCCHHHHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
TPFALDLGVGPLVSPRAIAEPPVFGRARAVALYDAVARRIVHRLKYEDRLDLAGVMARMM
CCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
AASGRTLIAEAECLVPVPLHRGRLWRRRFNQSALLARAIAASAGRPCVATALVRVRATRS
HHCCCEEEEECCEEECCCCHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
QVGLSRAARAENLSGAFRVTAAEQHRIRGRRVLLVDDVMTTGATGNAAARALLRGGATSV
HHHHHHHHHHHCCCCEEEEEEHHHHHHCCCEEEEEECHHHCCCCCHHHHHHHHHCCCCHH
DLLTFALVGDPAG
HHHHHHHHCCCCC
>Mature Secondary Structure 
TALQAVATALRGLPRGVVSLVYPPTCAGCGSATADPGAFCPSCWSSLRLIEEPVCQRYG
HHHHHHHHHHHCCCHHHHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
TPFALDLGVGPLVSPRAIAEPPVFGRARAVALYDAVARRIVHRLKYEDRLDLAGVMARMM
CCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
AASGRTLIAEAECLVPVPLHRGRLWRRRFNQSALLARAIAASAGRPCVATALVRVRATRS
HHCCCEEEEECCEEECCCCHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
QVGLSRAARAENLSGAFRVTAAEQHRIRGRRVLLVDDVMTTGATGNAAARALLRGGATSV
HHHHHHHHHHHCCCCEEEEEEHHHHHHCCCEEEEEECHHHCCCCCHHHHHHHHHCCCCHH
DLLTFALVGDPAG
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]