Click here to switch to the map view.

The map label for this gene is mog [H]

Identifier: 170748995

GI number: 170748995

Start: 2740765

End: 2741319

Strand: Reverse

Name: mog [H]

Synonym: Mrad2831_2585

Alternate gene names: 170748995

Gene position: 2741319-2740765 (Counterclockwise)

Preceding gene: 170748996

Following gene: 170748985

Centisome position: 45.1

GC content: 73.15

Gene sequence:

>555_bases
ATGGTGGCTCGCATCGGCATCCTCACCGTGTCGGACCGCGCCGCGGCGGGCGTCTACGCGGACGAGGGCGGCCCTGCCAT
CCGGGCGGAGCTCACGCGCCTGCTCGCCTCGCCCTGGGAGCCGGTGCACAGGATCGTGCCCGACGGGGTCGAGAGCGTGC
GCGACGCCATCGTCGAACTCGTGGACGGCGAGGGCTGCGGCCTCGTGCTGACGACCGGTGGGACGGGCCCGACCCCGCGC
GACCTCACGCCGGAGGGCACCGAGGCGGCCTGCGAGCGGATGATGCCGGGCTTCGGCGAACTGCTGCGCATGAGGAGCCT
GGAACAGGTGCCAACCGCCATCCTGTCGCGGCAGACGGCCGGCATCCGAGGCAAGGCCCTGGTGGTCAACCTGCCGGGCC
GCCCGTCATCGATCCGCGTGTCGCTTCTGGCGGTGATGCCGGCCATTCCCTACTGTCTCGACCTAATCGGCGCCGCCCTC
GTCGACACCGACCCGGCCATCCTGTCGGCGTTCCGGCCCGCCCTCGGGGCGCCGGCTCCCGGTCGGCGCACATGA

Upstream 100 bases:

>100_bases
CGCCATCGCGCGCAAGCCCAAGGGCCACGACTTCGTCGCCGACCGCATCTCCGCTCCCGCCGTCGCGCGGCACATGAGCG
TCACCGGGGGATAGGACGCC

Downstream 100 bases:

>100_bases
TGAAGCTCGCGATCTGCCTCGTGATCTACGGCCGCGGACGCAATTCCGACGCGGCCCTCACCCCGACGCGGCCCTCGCCA
AGGTCGTCCGTCGGCTGACT

Product: molybdenum cofactor synthesis domain-containing protein

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MVARIGILTVSDRAAAGVYADEGGPAIRAELTRLLASPWEPVHRIVPDGVESVRDAIVELVDGEGCGLVLTTGGTGPTPR
DLTPEGTEAACERMMPGFGELLRMRSLEQVPTAILSRQTAGIRGKALVVNLPGRPSSIRVSLLAVMPAIPYCLDLIGAAL
VDTDPAILSAFRPALGAPAPGRRT

Sequences:

>Translated_184_residues
MVARIGILTVSDRAAAGVYADEGGPAIRAELTRLLASPWEPVHRIVPDGVESVRDAIVELVDGEGCGLVLTTGGTGPTPR
DLTPEGTEAACERMMPGFGELLRMRSLEQVPTAILSRQTAGIRGKALVVNLPGRPSSIRVSLLAVMPAIPYCLDLIGAAL
VDTDPAILSAFRPALGAPAPGRRT
>Mature_184_residues
MVARIGILTVSDRAAAGVYADEGGPAIRAELTRLLASPWEPVHRIVPDGVESVRDAIVELVDGEGCGLVLTTGGTGPTPR
DLTPEGTEAACERMMPGFGELLRMRSLEQVPTAILSRQTAGIRGKALVVNLPGRPSSIRVSLLAVMPAIPYCLDLIGAAL
VDTDPAILSAFRPALGAPAPGRRT

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=163, Percent_Identity=37.4233128834356, Blast_Score=111, Evalue=4e-25,
Organism=Homo sapiens, GI66932975, Length=163, Percent_Identity=37.4233128834356, Blast_Score=111, Evalue=4e-25,
Organism=Escherichia coli, GI1786190, Length=182, Percent_Identity=47.8021978021978, Blast_Score=167, Evalue=4e-43,
Organism=Escherichia coli, GI1787000, Length=149, Percent_Identity=32.2147651006711, Blast_Score=66, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17564954, Length=157, Percent_Identity=36.3057324840764, Blast_Score=90, Evalue=7e-19,
Organism=Drosophila melanogaster, GI17136978, Length=152, Percent_Identity=32.8947368421053, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24638841, Length=152, Percent_Identity=32.8947368421053, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 19169; Mature: 19169

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVARIGILTVSDRAAAGVYADEGGPAIRAELTRLLASPWEPVHRIVPDGVESVRDAIVEL
CCEEEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHH
VDGEGCGLVLTTGGTGPTPRDLTPEGTEAACERMMPGFGELLRMRSLEQVPTAILSRQTA
HCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
GIRGKALVVNLPGRPSSIRVSLLAVMPAIPYCLDLIGAALVDTDPAILSAFRPALGAPAP
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
GRRT
CCCC
>Mature Secondary Structure
MVARIGILTVSDRAAAGVYADEGGPAIRAELTRLLASPWEPVHRIVPDGVESVRDAIVEL
CCEEEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHH
VDGEGCGLVLTTGGTGPTPRDLTPEGTEAACERMMPGFGELLRMRSLEQVPTAILSRQTA
HCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
GIRGKALVVNLPGRPSSIRVSLLAVMPAIPYCLDLIGAALVDTDPAILSAFRPALGAPAP
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
GRRT
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]