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The map label for this gene is ompR [H]

Identifier: 170748891

GI number: 170748891

Start: 2635054

End: 2635809

Strand: Reverse

Name: ompR [H]

Synonym: Mrad2831_2473

Alternate gene names: 170748891

Gene position: 2635809-2635054 (Counterclockwise)

Preceding gene: 170748901

Following gene: 170748890

Centisome position: 43.37

GC content: 70.37

Gene sequence:

>756_bases
ATGATGCAGGCCGACCCGCAGACCGACTCCTTTGCGATGAGCGCACCCGCAACACCCCACATCCTCGTCGTCGAGGACGA
TCGGGAGATCTCGGCGCTGATCGCGCGCTACCTGCGCGGCAACGATTGCCGCGTCACGCTGGCCGGGGACGGCACCGACA
TGGACCGGGTCCTGGCGGAGGCGCGCATCGACCTCATCGTGCTCGACCTGATGCTTCCCGGCGAGGACGGTCTGAGCCTG
TGCAAGCGCCTGCGCGGCACCTCGCAGATCCCGATCCTGATCCTGACCGCGAAGTCCGAGGACGTGGACCGGATCCTCGG
CCTCGAACTCGGCGCCGACGACTACCTCGCCAAGCCGTTCAACCCGCGGGAACTGCTCGCCCGGATCCGCGCGATCCTGC
GCCGGGTCGCCGCCGAGGCGCCGGACGCGGACGAGCGGCGGCGGCTGCACTTCTCCGGCTGGACCCTCGACGTCTCCCTG
CGACAGGTGCTCTCCCCCGAGGGCGCCCGCATCTCGATCACCGGGGCGGAGTTCGACCTGCTCCACGCCCTGTGTCTCCG
GCCGGGGCGGGTGCTGTCGCGGGACCAGCTCCTCGACCTCACCCAGGGCCGGGCCGCGGGCCCGTTCGAGCGGAGCATCG
ACGTGCTGATCTCGCGGATCCGCCAGAAGATCGAGCGCGACACCCGCAACCCCGAGTTCATCCGCACGATCCGGTCCGGC
GGCTACCTGTTCACGCCCGAGGTCACGCGGTCATGA

Upstream 100 bases:

>100_bases
GTTCGGCAACTCAGTTCAGGTCCGTGCGGGAAACACGCGCTTACAAAATGGTTCCGTGCCCCACCTTCGAATAATCGGCG
GATGGCGTCATAATAGCCTG

Downstream 100 bases:

>100_bases
GCGGCCTGGGGCGGCTCCGCGCGCGGCTGCGCCCGAAGACCATCGCGGGCCAGATCGCGCTGCTCGTGGTCGCCGGCATC
GCGGTCGCCCACGTGGTCGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MMQADPQTDSFAMSAPATPHILVVEDDREISALIARYLRGNDCRVTLAGDGTDMDRVLAEARIDLIVLDLMLPGEDGLSL
CKRLRGTSQIPILILTAKSEDVDRILGLELGADDYLAKPFNPRELLARIRAILRRVAAEAPDADERRRLHFSGWTLDVSL
RQVLSPEGARISITGAEFDLLHALCLRPGRVLSRDQLLDLTQGRAAGPFERSIDVLISRIRQKIERDTRNPEFIRTIRSG
GYLFTPEVTRS

Sequences:

>Translated_251_residues
MMQADPQTDSFAMSAPATPHILVVEDDREISALIARYLRGNDCRVTLAGDGTDMDRVLAEARIDLIVLDLMLPGEDGLSL
CKRLRGTSQIPILILTAKSEDVDRILGLELGADDYLAKPFNPRELLARIRAILRRVAAEAPDADERRRLHFSGWTLDVSL
RQVLSPEGARISITGAEFDLLHALCLRPGRVLSRDQLLDLTQGRAAGPFERSIDVLISRIRQKIERDTRNPEFIRTIRSG
GYLFTPEVTRS
>Mature_251_residues
MMQADPQTDSFAMSAPATPHILVVEDDREISALIARYLRGNDCRVTLAGDGTDMDRVLAEARIDLIVLDLMLPGEDGLSL
CKRLRGTSQIPILILTAKSEDVDRILGLELGADDYLAKPFNPRELLARIRAILRRVAAEAPDADERRRLHFSGWTLDVSL
RQVLSPEGARISITGAEFDLLHALCLRPGRVLSRDQLLDLTQGRAAGPFERSIDVLISRIRQKIERDTRNPEFIRTIRSG
GYLFTPEVTRS

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=48.2905982905983, Blast_Score=209, Evalue=9e-56,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=39.5652173913043, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=40.343347639485, Blast_Score=156, Evalue=9e-40,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=41.991341991342, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=36.2068965517241, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=37.719298245614, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=35.7446808510638, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=37.117903930131, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=37.6106194690265, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=35.5555555555556, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=34.9557522123894, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=34.8214285714286, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=35.8078602620087, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=33.1838565022422, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1790299, Length=139, Percent_Identity=29.4964028776978, Blast_Score=65, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=102, Percent_Identity=34.3137254901961, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28010; Mature: 28010

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQADPQTDSFAMSAPATPHILVVEDDREISALIARYLRGNDCRVTLAGDGTDMDRVLAE
CCCCCCCCCCEEECCCCCCEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
ARIDLIVLDLMLPGEDGLSLCKRLRGTSQIPILILTAKSEDVDRILGLELGADDYLAKPF
HHHCEEEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHCEECCCCHHCCCC
NPRELLARIRAILRRVAAEAPDADERRRLHFSGWTLDVSLRQVLSPEGARISITGAEFDL
CHHHHHHHHHHHHHHHHHCCCCCHHHCEEEECCEEEEHHHHHHHCCCCCEEEEECCHHHH
LHALCLRPGRVLSRDQLLDLTQGRAAGPFERSIDVLISRIRQKIERDTRNPEFIRTIRSG
HHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
GYLFTPEVTRS
CEEECCCCCCC
>Mature Secondary Structure
MMQADPQTDSFAMSAPATPHILVVEDDREISALIARYLRGNDCRVTLAGDGTDMDRVLAE
CCCCCCCCCCEEECCCCCCEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
ARIDLIVLDLMLPGEDGLSLCKRLRGTSQIPILILTAKSEDVDRILGLELGADDYLAKPF
HHHCEEEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHCEECCCCHHCCCC
NPRELLARIRAILRRVAAEAPDADERRRLHFSGWTLDVSLRQVLSPEGARISITGAEFDL
CHHHHHHHHHHHHHHHHHCCCCCHHHCEEEECCEEEEHHHHHHHCCCCCEEEEECCHHHH
LHALCLRPGRVLSRDQLLDLTQGRAAGPFERSIDVLISRIRQKIERDTRNPEFIRTIRSG
HHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
GYLFTPEVTRS
CEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]