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The map label for this gene is rfbC [C]

Identifier: 170748798

GI number: 170748798

Start: 2522729

End: 2523280

Strand: Reverse

Name: rfbC [C]

Synonym: Mrad2831_2380

Alternate gene names: 170748798

Gene position: 2523280-2522729 (Counterclockwise)

Preceding gene: 170748800

Following gene: 170748797

Centisome position: 41.52

GC content: 68.48

Gene sequence:

>552_bases
ATGGACGTCATCGAGACCGAGATCCCCGACGTGAAGCGCATCGTCCTGAAGCGCTTCGGCGACGCGCGGGGCTGGTTCTC
GGAGACCTTCCGGGCCGACACCCTGGCGCGGGCCGGGATCGCCACGCCGTTCATCCAGGACAACCAGTCCTTCTCGGCCC
CGCAGGGGACGGTCCGCGGCCTCCACTTCCAGATCGCCCCCCGCGCGCAGGCCAAGCTGATCCGCGTGCTGCAGGGCGCG
ATCCTCGACGTGGCGGTCGATATCCGCAGCGACTCGCCGACCTACGGGAAGTACGTCGCCGTCACCCTCGACGCCGAGAA
GGGCGAGCAGCTCTACATCCCGCACGGCTTCGCGCACGGCTTCTGCACCCTGACCCCCGACGTGATGGTCACCTACAAGG
TCGACGACTACTACAGCCCCGAGCACGACCGCGCGCTGTTCTGGAACGATCCGGCGATCGGGATCCCGTGGCCGGTCTCG
GGAGAGGCGGCGATCCTGTCCGACAAGGATCGCCGGGCGCCCAAGCTCGCCGATCTCGGCAGCGTCTTCTGA

Upstream 100 bases:

>100_bases
CACCGAGGTTGTGGTCGGCGAGGCGGGCGCGCGACCCGGAACGACCGACGCGGAGACGTCCGCTGGACCTCCCGACGGGA
TCCGCAAGAGGGGCGCTGGC

Downstream 100 bases:

>100_bases
AGAGCGCGGCCCGGCCGCAATTTTGTCACGTCGGCCGGTCTTAGGCTGCCCCGGCTTTCTCAGTTCTCGATCGATCCGAA
GAGGTAATCCGCCATGCGCA

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MDVIETEIPDVKRIVLKRFGDARGWFSETFRADTLARAGIATPFIQDNQSFSAPQGTVRGLHFQIAPRAQAKLIRVLQGA
ILDVAVDIRSDSPTYGKYVAVTLDAEKGEQLYIPHGFAHGFCTLTPDVMVTYKVDDYYSPEHDRALFWNDPAIGIPWPVS
GEAAILSDKDRRAPKLADLGSVF

Sequences:

>Translated_183_residues
MDVIETEIPDVKRIVLKRFGDARGWFSETFRADTLARAGIATPFIQDNQSFSAPQGTVRGLHFQIAPRAQAKLIRVLQGA
ILDVAVDIRSDSPTYGKYVAVTLDAEKGEQLYIPHGFAHGFCTLTPDVMVTYKVDDYYSPEHDRALFWNDPAIGIPWPVS
GEAAILSDKDRRAPKLADLGSVF
>Mature_183_residues
MDVIETEIPDVKRIVLKRFGDARGWFSETFRADTLARAGIATPFIQDNQSFSAPQGTVRGLHFQIAPRAQAKLIRVLQGA
ILDVAVDIRSDSPTYGKYVAVTLDAEKGEQLYIPHGFAHGFCTLTPDVMVTYKVDDYYSPEHDRALFWNDPAIGIPWPVS
GEAAILSDKDRRAPKLADLGSVF

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=180, Percent_Identity=46.1111111111111, Blast_Score=152, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17550412, Length=181, Percent_Identity=39.7790055248619, Blast_Score=111, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20280; Mature: 20280

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVIETEIPDVKRIVLKRFGDARGWFSETFRADTLARAGIATPFIQDNQSFSAPQGTVRG
CCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEE
LHFQIAPRAQAKLIRVLQGAILDVAVDIRSDSPTYGKYVAVTLDAEKGEQLYIPHGFAHG
EEEEECCHHHHHHHHHHHHHHEEEEEEECCCCCCCCEEEEEEEECCCCCEEEEECCCCCC
FCTLTPDVMVTYKVDDYYSPEHDRALFWNDPAIGIPWPVSGEAAILSDKDRRAPKLADLG
EEEECCCEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCC
SVF
CCC
>Mature Secondary Structure
MDVIETEIPDVKRIVLKRFGDARGWFSETFRADTLARAGIATPFIQDNQSFSAPQGTVRG
CCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEE
LHFQIAPRAQAKLIRVLQGAILDVAVDIRSDSPTYGKYVAVTLDAEKGEQLYIPHGFAHG
EEEEECCHHHHHHHHHHHHHHEEEEEEECCCCCCCCEEEEEEEECCCCCEEEEECCCCCC
FCTLTPDVMVTYKVDDYYSPEHDRALFWNDPAIGIPWPVSGEAAILSDKDRRAPKLADLG
EEEECCCEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCC
SVF
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]