BacMap

Definition	Methylobacterium radiotolerans JCM 2831 chromosome, complete genome.
Accession	NC_010505
Length	6,077,833

Click here to switch to the map view.

The map label for this gene is yvaG [H]

Identifier: 170748140

GI number: 170748140

Start: 1831654

End: 1832433

Strand: Reverse

Name: yvaG [H]

Synonym: Mrad2831_1722

Alternate gene names: 170748140

Gene position: 1832433-1831654 (Counterclockwise)

Preceding gene: 170748141

Following gene: 170748139

Centisome position: 30.15

GC content: 74.36

Gene sequence:

>780_bases
ATGGATCTCGGCTTGAGCGGGCGCCGGGCGCTCGTCTGCGCGGCGAGCAAGGGGCTCGGCAAGGGCTGCGCCCTGGCGCT
CGCCCGGGAGGGCGTCGCGGTGACGATCACGGCCCGCACCGCGGAGACGCTGGAGCGGACCGCGGACGAGATCCGCGCCG
CGACAGGTGCCACCGTGACCACCGTCGCGGGCGACATCGCCACCGAGGCCGGCCGGGCCGCCGCGCTCGCCGCCTGCCCC
GAGCCCGACATCCTGGTCAACAATGCCGGCGGCCCGCCCCCCGGCGATTTCCGCGAGTGGGACCGCGACGCCTGGATCCG
GGCGCTCGACGCCAACATGCTGGCGCCGATCGCGCTCATCAAGGCGACGGTCGACGGGATGATCGGCCGCGGGTTCGGCC
GGATCGTCAACATCACCTCCGGCGCCGTGAAGGCGCCGATCGAGCATCTCGGCCTGTCGAACGGCGCCCGCTCGGGGCTG
ACGGGCTTCGTGGCCGGGCTCGCGCGGACGACCGTGCGGCACGGCGTGACGATCAACAACCTGCTGCCCGGCCCCTTCGA
CACCGACCGGATCCGCAGCAACGCGGCGGCGGGGGCCGCCAAGGCCGGCACCACCGTGGAGGCGTTCCTGGAGGCGCGGG
CGCGCGACAACCCCGCCGGCCGCTTCGGCCACCCCGACGAGTTCGGCGCCGCCTGCGCGTTCCTGTGCAGCCAGCAGGCG
GGCTTCATCACCGGGCAGAACCTGCTGATGGATGGCGGCGCCTATCCCGGCACGTTCTGA

Upstream 100 bases:

>100_bases
CGCCCCGCGCCCTGTCCCGGCCCGCTTCCGGGGACGGCCCCCGGCGCGCTATGACGCGCCGGGCGCCCTCGCGGCGAGGG
CCGGCTCACGGAGGCTTCCC

Downstream 100 bases:

>100_bases
CGCGGACCGGCCCTCCGTTTGCAGGGGCGGGCCGGATCACATCGTGCGGTGAGGACCATGAGCGTACGCGAGACCGTCGA
GGAGCGTCTGGCCCGGATCG

Product: short-chain dehydrogenase/reductase SDR

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MDLGLSGRRALVCAASKGLGKGCALALAREGVAVTITARTAETLERTADEIRAATGATVTTVAGDIATEAGRAAALAACP
EPDILVNNAGGPPPGDFREWDRDAWIRALDANMLAPIALIKATVDGMIGRGFGRIVNITSGAVKAPIEHLGLSNGARSGL
TGFVAGLARTTVRHGVTINNLLPGPFDTDRIRSNAAAGAAKAGTTVEAFLEARARDNPAGRFGHPDEFGAACAFLCSQQA
GFITGQNLLMDGGAYPGTF

Sequences:

>Translated_259_residues
MDLGLSGRRALVCAASKGLGKGCALALAREGVAVTITARTAETLERTADEIRAATGATVTTVAGDIATEAGRAAALAACP
EPDILVNNAGGPPPGDFREWDRDAWIRALDANMLAPIALIKATVDGMIGRGFGRIVNITSGAVKAPIEHLGLSNGARSGL
TGFVAGLARTTVRHGVTINNLLPGPFDTDRIRSNAAAGAAKAGTTVEAFLEARARDNPAGRFGHPDEFGAACAFLCSQQA
GFITGQNLLMDGGAYPGTF
>Mature_259_residues
MDLGLSGRRALVCAASKGLGKGCALALAREGVAVTITARTAETLERTADEIRAATGATVTTVAGDIATEAGRAAALAACP
EPDILVNNAGGPPPGDFREWDRDAWIRALDANMLAPIALIKATVDGMIGRGFGRIVNITSGAVKAPIEHLGLSNGARSGL
TGFVAGLARTTVRHGVTINNLLPGPFDTDRIRSNAAAGAAKAGTTVEAFLEARARDNPAGRFGHPDEFGAACAFLCSQQA
GFITGQNLLMDGGAYPGTF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=27.9527559055118, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=28.7937743190661, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=25.296442687747, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7705925, Length=256, Percent_Identity=27.34375, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI226371731, Length=184, Percent_Identity=28.2608695652174, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=26.5060240963855, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI66933014, Length=231, Percent_Identity=24.6753246753247, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI7706318, Length=207, Percent_Identity=26.5700483091787, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=255, Percent_Identity=32.156862745098, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=31.9230769230769, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=28.4, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=27.1317829457364, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082160, Length=267, Percent_Identity=27.7153558052434, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1787905, Length=258, Percent_Identity=27.1317829457364, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1789208, Length=264, Percent_Identity=27.6515151515151, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=26.0700389105058, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI2367365, Length=255, Percent_Identity=29.0196078431373, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=29.811320754717, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=29.811320754717, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=28.515625, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=31.0606060606061, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=29.0566037735849, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=29.4339622641509, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=28.3524904214559, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=27.9245283018868, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=27.9245283018868, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=27.4809160305344, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=27.2030651340996, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=28, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=266, Percent_Identity=30.8270676691729, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=27.1698113207547, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=27.8195488721804, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=27.3076923076923, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=28.2352941176471, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=28.8973384030418, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=26.6917293233083, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=25.6704980842912, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=261, Percent_Identity=27.9693486590038, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=272, Percent_Identity=27.2058823529412, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=27.5193798449612, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=256, Percent_Identity=26.171875, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=27.0588235294118, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=25.6603773584906, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=31.3492063492063, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24644339, Length=257, Percent_Identity=28.4046692607004, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=31.3253012048193, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=29.6875, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=27.1653543307087, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24639444, Length=263, Percent_Identity=26.615969581749, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644337, Length=171, Percent_Identity=28.6549707602339, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 26411; Mature: 26411

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGLSGRRALVCAASKGLGKGCALALAREGVAVTITARTAETLERTADEIRAATGATVT
CCCCCCCCEEEEEECCCCCCCHHHHHEECCCEEEEEECCCHHHHHHHHHHHHHHCCCEEE
TVAGDIATEAGRAAALAACPEPDILVNNAGGPPPGDFREWDRDAWIRALDANMLAPIALI
EHHHHHHHHCCCCEEEECCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
KATVDGMIGRGFGRIVNITSGAVKAPIEHLGLSNGARSGLTGFVAGLARTTVRHGVTINN
HHHHHHHHHCCCCCEEEECCCHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEC
LLPGPFDTDRIRSNAAAGAAKAGTTVEAFLEARARDNPAGRFGHPDEFGAACAFLCSQQA
CCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCC
GFITGQNLLMDGGAYPGTF
CEEECCCEEEECCCCCCCC
>Mature Secondary Structure
MDLGLSGRRALVCAASKGLGKGCALALAREGVAVTITARTAETLERTADEIRAATGATVT
CCCCCCCCEEEEEECCCCCCCHHHHHEECCCEEEEEECCCHHHHHHHHHHHHHHCCCEEE
TVAGDIATEAGRAAALAACPEPDILVNNAGGPPPGDFREWDRDAWIRALDANMLAPIALI
EHHHHHHHHCCCCEEEECCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
KATVDGMIGRGFGRIVNITSGAVKAPIEHLGLSNGARSGLTGFVAGLARTTVRHGVTINN
HHHHHHHHHCCCCCEEEECCCHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEC
LLPGPFDTDRIRSNAAAGAAKAGTTVEAFLEARARDNPAGRFGHPDEFGAACAFLCSQQA
CCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCC
GFITGQNLLMDGGAYPGTF
CEEECCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]