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The map label for this gene is dehH1 [H]

Identifier: 170748079

GI number: 170748079

Start: 1772280

End: 1773164

Strand: Reverse

Name: dehH1 [H]

Synonym: Mrad2831_1661

Alternate gene names: 170748079

Gene position: 1773164-1772280 (Counterclockwise)

Preceding gene: 170748082

Following gene: 170748078

Centisome position: 29.17

GC content: 72.66

Gene sequence:

>885_bases
ATGGCCCGCGACTTCCTGCCGGGATTCGACCGGCACCGGATCGAGACCGCGCCCGGCGTGACGATCAACGCCCGCTCGGC
CGGATCCGGGCCGCCGGTGCTGCTGCTGCACGGCCATCCCCAGACCCTGTCGACGTGGCTCCAGGTCGCGCCGCGCCTCG
CGGAGCGGCACGCCGTGGTGGCGATGGACCTGCGCGGCTACGGCGATTCGTCGAAGCCCCCCGGGGGCGAGCGCCACGCC
AACTACGCCAAGCGCGCCATGGCGGCGGACGCGGCGGCCCTGATGCGGGCGCTCGGGCACGAACGCTTCGCCGTCGTCGG
GCATGACCGCGGCGGCCGCGTCGCCCACCGCCTCGCCCTCGACCACAGCCGGGCGGTGGAGCGGATCGCCGTGTTCGACA
TCGCGCCCACCGCGACCATGTACGCGCGCACCGACAAGGATTTCGCCACCCGCTATTTCTGGTGGTTCTTCTTCATCCAG
CCCCATCCCCTGCCGGAGACGCTGATCGGGGCCGATCCGGAATATTTCCTGCGCCACCACGTCGACGGCCAGTCCAAGAC
CCCCGGCTCGACCCCGCCGGAACTCTTCGCCGAGTACCTGCGCTGCTACGCCGACCCGGCCTGCCGCCACGCGATCTGCG
AGGATTACCGGGCCGCCGCCGGGATCGACCTGGAGCACGACGCGGCCGATGCCGAGGCCCGGATCACCGCGCCGCTGCTG
GCGCTCTGGGGGGCGAAGGGCGTGGTCGGCCGGACCTACGACGTGCTGGAGACGTGGCGCGAGAAGGCGACCGACGTCTC
GGGCCGGGCGCTGGATTGCGGCCACACCCTCCAGGAGGAGCGGCCGGACGCGGTTCTCTCGGAGTTGGCGGCGTTCCTGC
GCTGA

Upstream 100 bases:

>100_bases
ATGGCGGTTCGGCGGACATGGTGCCGGAGGCGCCTTATCATCCGGTGCATCCCGGCGCGCCAGTGCGGCAGGATGGAGAC
CGAACCCGGAGACCGATCCC

Downstream 100 bases:

>100_bases
GCCGGCCGCCGGCCCGGAACAGATCGACCGCGCTGTCGTAGCCCGCGTCGCAGATCCGGCCGCGCGCCGGGAACAGACCG
GCGGCGATCAGCCGGTCGTA

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MARDFLPGFDRHRIETAPGVTINARSAGSGPPVLLLHGHPQTLSTWLQVAPRLAERHAVVAMDLRGYGDSSKPPGGERHA
NYAKRAMAADAAALMRALGHERFAVVGHDRGGRVAHRLALDHSRAVERIAVFDIAPTATMYARTDKDFATRYFWWFFFIQ
PHPLPETLIGADPEYFLRHHVDGQSKTPGSTPPELFAEYLRCYADPACRHAICEDYRAAAGIDLEHDAADAEARITAPLL
ALWGAKGVVGRTYDVLETWREKATDVSGRALDCGHTLQEERPDAVLSELAAFLR

Sequences:

>Translated_294_residues
MARDFLPGFDRHRIETAPGVTINARSAGSGPPVLLLHGHPQTLSTWLQVAPRLAERHAVVAMDLRGYGDSSKPPGGERHA
NYAKRAMAADAAALMRALGHERFAVVGHDRGGRVAHRLALDHSRAVERIAVFDIAPTATMYARTDKDFATRYFWWFFFIQ
PHPLPETLIGADPEYFLRHHVDGQSKTPGSTPPELFAEYLRCYADPACRHAICEDYRAAAGIDLEHDAADAEARITAPLL
ALWGAKGVVGRTYDVLETWREKATDVSGRALDCGHTLQEERPDAVLSELAAFLR
>Mature_293_residues
ARDFLPGFDRHRIETAPGVTINARSAGSGPPVLLLHGHPQTLSTWLQVAPRLAERHAVVAMDLRGYGDSSKPPGGERHAN
YAKRAMAADAAALMRALGHERFAVVGHDRGGRVAHRLALDHSRAVERIAVFDIAPTATMYARTDKDFATRYFWWFFFIQP
HPLPETLIGADPEYFLRHHVDGQSKTPGSTPPELFAEYLRCYADPACRHAICEDYRAAAGIDLEHDAADAEARITAPLLA
LWGAKGVVGRTYDVLETWREKATDVSGRALDCGHTLQEERPDAVLSELAAFLR

Specific function: Unknown

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=275, Percent_Identity=23.6363636363636, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI218777840, Length=276, Percent_Identity=26.8115942028986, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI13376164, Length=276, Percent_Identity=26.8115942028986, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI27597073, Length=121, Percent_Identity=32.2314049586777, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17554012, Length=303, Percent_Identity=25.4125412541254, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.3 [H]

Molecular weight: Translated: 32451; Mature: 32320

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARDFLPGFDRHRIETAPGVTINARSAGSGPPVLLLHGHPQTLSTWLQVAPRLAERHAVV
CCCCCCCCCCCCCEECCCCCEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCEEE
AMDLRGYGDSSKPPGGERHANYAKRAMAADAAALMRALGHERFAVVGHDRGGRVAHRLAL
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
DHSRAVERIAVFDIAPTATMYARTDKDFATRYFWWFFFIQPHPLPETLIGADPEYFLRHH
HHHHHHHHHHEEECCCCHHHEEECCHHHHHHEEEEEEEECCCCCCHHHHCCCHHHHHHHC
VDGQSKTPGSTPPELFAEYLRCYADPACRHAICEDYRAAAGIDLEHDAADAEARITAPLL
CCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
ALWGAKGVVGRTYDVLETWREKATDVSGRALDCGHTLQEERPDAVLSELAAFLR
HHHCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCHHHHCCHHHHHHHHHHHHC
>Mature Secondary Structure 
ARDFLPGFDRHRIETAPGVTINARSAGSGPPVLLLHGHPQTLSTWLQVAPRLAERHAVV
CCCCCCCCCCCCEECCCCCEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCEEE
AMDLRGYGDSSKPPGGERHANYAKRAMAADAAALMRALGHERFAVVGHDRGGRVAHRLAL
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
DHSRAVERIAVFDIAPTATMYARTDKDFATRYFWWFFFIQPHPLPETLIGADPEYFLRHH
HHHHHHHHHHEEECCCCHHHEEECCHHHHHHEEEEEEEECCCCCCHHHHCCCHHHHHHHC
VDGQSKTPGSTPPELFAEYLRCYADPACRHAICEDYRAAAGIDLEHDAADAEARITAPLL
CCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
ALWGAKGVVGRTYDVLETWREKATDVSGRALDCGHTLQEERPDAVLSELAAFLR
HHHCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCHHHHCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1512562 [H]