| Definition | Methylobacterium radiotolerans JCM 2831 chromosome, complete genome. |
|---|---|
| Accession | NC_010505 |
| Length | 6,077,833 |
Click here to switch to the map view.
The map label for this gene is yqjQ [H]
Identifier: 170747700
GI number: 170747700
Start: 1339348
End: 1340163
Strand: Reverse
Name: yqjQ [H]
Synonym: Mrad2831_1275
Alternate gene names: 170747700
Gene position: 1340163-1339348 (Counterclockwise)
Preceding gene: 170747703
Following gene: 170747695
Centisome position: 22.05
GC content: 73.41
Gene sequence:
>816_bases ATGACGGATCGTGCCAAGGGAATTGCTCTGATCACCGGCGCTTCGGGCGGGATCGGTGCGATCTATGCCGAACAGCTCGC CGCGCGCGGCTACGATCTCATCCTGACCGCCCGGAACGCGGATCGCCTGGAGGCGGTCGCGGAGACGGTGCGCGGGGCCT CCGGCCGCACCGTCGAGGCGCTCGCGGCGGATATCAACGACCGTGCCGGTCTTCGGCGCGTCGAGGACCGGCTGCGGGGC GACGCGGCGATCACCCTGCTGGTCAACAACGCCGGCTTCGGCTCGGCGGCCCCGCTGCTCCAGGCGGATCCGGACGAGAT GGAGCGCATGATCGGCGTGAACGTCACGGCCGTGACGCGCCTCGCCTACGCGGCGGCGCCGGCCTTCGTCGCGCGGGGGC ACGGGGCGATCATCAACGTCGCCTCGACCGTCGCCCTCAATCCCGAGCTGCTCAACGGCGTCTACGGGGCCAGCAAGGCT TACGTCCTGGCCTTCACCCAGGCGCTGCAGCACGAACTCGCCCCCAAGGGCGTCCGGATCCAGGCGGTCCTGCCCGGCGC GACGGCGACGGAGTTCTGGACCGTGGCCGGCGTCGGCGGCCACCGGAACCTCCCGGCCAGCATCGTCATGACGCCGGCCG ATCTGGTCGCGGCCGCGCTGGCCGGGTTCGATGCCGGCGAGGTCGTCACGATCCCGCCCCTGGAGAACGGCGCGGCCTGG TCCGCGCTGGACGCCGCGCGCCTCGAACTCGCCGCCCAGCTCGGCGCGTCGGCGCCGGCGAGCCGGTACCGGAGCGCGCG CGCCGTCGCGGCCTGA
Upstream 100 bases:
>100_bases TCATACCAAGGTATGGCGTCGCCCCGCGTCGGTATAAATGTCCGGCTCCGTCCCGGTCGCTACACTTTCCGTCATCCAAC AGCGCAGACGGAGAGTTGTC
Downstream 100 bases:
>100_bases GGCGCCCGCGGGGGCGCCCCGACCGGGGACCCCTGCCCACTCCCCGCGGCGGGTCGGTCAGGCCCGGGCGAGCGGCAGGC GCACCGTGAACCGGGCGCCC
Product: short-chain dehydrogenase/reductase SDR
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 271; Mature: 270
Protein sequence:
>271_residues MTDRAKGIALITGASGGIGAIYAEQLAARGYDLILTARNADRLEAVAETVRGASGRTVEALAADINDRAGLRRVEDRLRG DAAITLLVNNAGFGSAAPLLQADPDEMERMIGVNVTAVTRLAYAAAPAFVARGHGAIINVASTVALNPELLNGVYGASKA YVLAFTQALQHELAPKGVRIQAVLPGATATEFWTVAGVGGHRNLPASIVMTPADLVAAALAGFDAGEVVTIPPLENGAAW SALDAARLELAAQLGASAPASRYRSARAVAA
Sequences:
>Translated_271_residues MTDRAKGIALITGASGGIGAIYAEQLAARGYDLILTARNADRLEAVAETVRGASGRTVEALAADINDRAGLRRVEDRLRG DAAITLLVNNAGFGSAAPLLQADPDEMERMIGVNVTAVTRLAYAAAPAFVARGHGAIINVASTVALNPELLNGVYGASKA YVLAFTQALQHELAPKGVRIQAVLPGATATEFWTVAGVGGHRNLPASIVMTPADLVAAALAGFDAGEVVTIPPLENGAAW SALDAARLELAAQLGASAPASRYRSARAVAA >Mature_270_residues TDRAKGIALITGASGGIGAIYAEQLAARGYDLILTARNADRLEAVAETVRGASGRTVEALAADINDRAGLRRVEDRLRGD AAITLLVNNAGFGSAAPLLQADPDEMERMIGVNVTAVTRLAYAAAPAFVARGHGAIINVASTVALNPELLNGVYGASKAY VLAFTQALQHELAPKGVRIQAVLPGATATEFWTVAGVGGHRNLPASIVMTPADLVAAALAGFDAGEVVTIPPLENGAAWS ALDAARLELAAQLGASAPASRYRSARAVAA
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG0300
COG function: function code R; Short-chain dehydrogenases of various substrate specificities
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI4557649, Length=185, Percent_Identity=37.8378378378378, Blast_Score=121, Evalue=7e-28, Organism=Homo sapiens, GI226371731, Length=185, Percent_Identity=33.5135135135135, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI7705855, Length=188, Percent_Identity=32.9787234042553, Blast_Score=110, Evalue=2e-24, Organism=Homo sapiens, GI40807363, Length=205, Percent_Identity=30.7317073170732, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI32483357, Length=202, Percent_Identity=29.2079207920792, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI33667109, Length=199, Percent_Identity=30.6532663316583, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI7657478, Length=186, Percent_Identity=30.1075268817204, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI5031737, Length=198, Percent_Identity=30.3030303030303, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI142976729, Length=192, Percent_Identity=31.25, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI7705925, Length=184, Percent_Identity=29.8913043478261, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI40254992, Length=186, Percent_Identity=28.494623655914, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI109715829, Length=193, Percent_Identity=30.5699481865285, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI15277342, Length=195, Percent_Identity=32.3076923076923, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI19743808, Length=186, Percent_Identity=31.1827956989247, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI150247226, Length=186, Percent_Identity=30.6451612903226, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1787335, Length=186, Percent_Identity=33.8709677419355, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1787820, Length=218, Percent_Identity=30.2752293577982, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1786701, Length=183, Percent_Identity=29.5081967213115, Blast_Score=75, Evalue=6e-15, Organism=Escherichia coli, GI87082100, Length=187, Percent_Identity=31.0160427807487, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1789208, Length=188, Percent_Identity=30.3191489361702, Blast_Score=72, Evalue=6e-14, Organism=Escherichia coli, GI1790717, Length=188, Percent_Identity=30.3191489361702, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1788459, Length=187, Percent_Identity=31.5508021390374, Blast_Score=65, Evalue=5e-12, Organism=Escherichia coli, GI87082160, Length=187, Percent_Identity=26.7379679144385, Blast_Score=64, Evalue=8e-12, Organism=Caenorhabditis elegans, GI71994600, Length=194, Percent_Identity=35.0515463917526, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI71994604, Length=193, Percent_Identity=33.160621761658, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI25152911, Length=193, Percent_Identity=32.6424870466321, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560220, Length=198, Percent_Identity=32.3232323232323, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17562904, Length=201, Percent_Identity=30.3482587064677, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI25147288, Length=185, Percent_Identity=29.7297297297297, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI212646214, Length=196, Percent_Identity=28.0612244897959, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17560332, Length=205, Percent_Identity=29.2682926829268, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17562910, Length=200, Percent_Identity=29, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI193204405, Length=200, Percent_Identity=30.5, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17555706, Length=182, Percent_Identity=31.3186813186813, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17560150, Length=196, Percent_Identity=31.6326530612245, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17562906, Length=208, Percent_Identity=31.25, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17563726, Length=205, Percent_Identity=28.780487804878, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17557668, Length=189, Percent_Identity=27.5132275132275, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17565030, Length=198, Percent_Identity=30.3030303030303, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17538480, Length=202, Percent_Identity=31.1881188118812, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17559104, Length=210, Percent_Identity=29.0476190476191, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17559552, Length=189, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17561402, Length=196, Percent_Identity=27.5510204081633, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17508895, Length=143, Percent_Identity=32.1678321678322, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI115534694, Length=187, Percent_Identity=32.0855614973262, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17560676, Length=200, Percent_Identity=26, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17560176, Length=197, Percent_Identity=28.4263959390863, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17544670, Length=208, Percent_Identity=27.8846153846154, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17562908, Length=209, Percent_Identity=30.1435406698565, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17538486, Length=205, Percent_Identity=27.8048780487805, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6319635, Length=186, Percent_Identity=29.5698924731183, Blast_Score=82, Evalue=8e-17, Organism=Saccharomyces cerevisiae, GI6323882, Length=197, Percent_Identity=33.502538071066, Blast_Score=79, Evalue=6e-16, Organism=Saccharomyces cerevisiae, GI6322067, Length=212, Percent_Identity=27.8301886792453, Blast_Score=72, Evalue=8e-14, Organism=Saccharomyces cerevisiae, GI6322861, Length=189, Percent_Identity=24.8677248677249, Blast_Score=65, Evalue=8e-12, Organism=Drosophila melanogaster, GI24640442, Length=190, Percent_Identity=34.2105263157895, Blast_Score=107, Evalue=6e-24, Organism=Drosophila melanogaster, GI24584752, Length=194, Percent_Identity=34.020618556701, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI28574402, Length=196, Percent_Identity=32.6530612244898, Blast_Score=100, Evalue=9e-22, Organism=Drosophila melanogaster, GI24584744, Length=196, Percent_Identity=32.6530612244898, Blast_Score=100, Evalue=9e-22, Organism=Drosophila melanogaster, GI161076933, Length=184, Percent_Identity=32.6086956521739, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI24584748, Length=184, Percent_Identity=32.6086956521739, Blast_Score=99, Evalue=4e-21, Organism=Drosophila melanogaster, GI28571526, Length=201, Percent_Identity=34.3283582089552, Blast_Score=98, Evalue=7e-21, Organism=Drosophila melanogaster, GI21357041, Length=194, Percent_Identity=34.5360824742268, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI23397609, Length=197, Percent_Identity=34.010152284264, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI24644339, Length=194, Percent_Identity=33.5051546391753, Blast_Score=87, Evalue=2e-17, Organism=Drosophila melanogaster, GI116007236, Length=197, Percent_Identity=29.4416243654822, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI116007238, Length=211, Percent_Identity=27.4881516587678, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24639444, Length=187, Percent_Identity=31.0160427807487, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI221331216, Length=201, Percent_Identity=27.363184079602, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24665247, Length=201, Percent_Identity=27.363184079602, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI21355319, Length=196, Percent_Identity=26.530612244898, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24648944, Length=196, Percent_Identity=29.0816326530612, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24665243, Length=206, Percent_Identity=27.6699029126214, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI221331218, Length=206, Percent_Identity=27.6699029126214, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24643142, Length=191, Percent_Identity=27.2251308900524, Blast_Score=64, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 27686; Mature: 27555
Theoretical pI: Translated: 6.28; Mature: 6.28
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 1.5 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 1.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTDRAKGIALITGASGGIGAIYAEQLAARGYDLILTARNADRLEAVAETVRGASGRTVEA CCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCCCCHHH LAADINDRAGLRRVEDRLRGDAAITLLVNNAGFGSAAPLLQADPDEMERMIGVNVTAVTR HHHCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHHH LAYAAAPAFVARGHGAIINVASTVALNPELLNGVYGASKAYVLAFTQALQHELAPKGVRI HHHHHCCHHHHCCCCEEEEEEHHEEECHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEE QAVLPGATATEFWTVAGVGGHRNLPASIVMTPADLVAAALAGFDAGEVVTIPPLENGAAW EEEECCCCCHHEEEEEECCCCCCCCCEEEECHHHHHHHHHHCCCCCCEEECCCCCCCCCH SALDAARLELAAQLGASAPASRYRSARAVAA HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC >Mature Secondary Structure TDRAKGIALITGASGGIGAIYAEQLAARGYDLILTARNADRLEAVAETVRGASGRTVEA CCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCCCCHHH LAADINDRAGLRRVEDRLRGDAAITLLVNNAGFGSAAPLLQADPDEMERMIGVNVTAVTR HHHCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHHH LAYAAAPAFVARGHGAIINVASTVALNPELLNGVYGASKAYVLAFTQALQHELAPKGVRI HHHHHCCHHHHCCCCEEEEEEHHEEECHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEE QAVLPGATATEFWTVAGVGGHRNLPASIVMTPADLVAAALAGFDAGEVVTIPPLENGAAW EEEECCCCCHHEEEEEECCCCCCCCCEEEECHHHHHHHHHHCCCCCCEEECCCCCCCCCH SALDAARLELAAQLGASAPASRYRSARAVAA HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8969508; 9384377 [H]