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The map label for this gene is gmhA [H]

Identifier: 170747652

GI number: 170747652

Start: 1289388

End: 1289975

Strand: Reverse

Name: gmhA [H]

Synonym: Mrad2831_1225

Alternate gene names: 170747652

Gene position: 1289975-1289388 (Counterclockwise)

Preceding gene: 170747653

Following gene: 170747651

Centisome position: 21.22

GC content: 71.6

Gene sequence:

>588_bases
ATGAGCGCGATCGTCGATTTTCTCACGCGGACCCGTGACACCTTCCAGGCCGCCCTCGACGATACCCGCTTCCACGCGAC
CCTCGCCGAGACCGCCGATCTCGTGACCGCGTCCCTGCGCGGCGGCGGCAAGCTCCTGACGATCGGCAACGGCGGCAGCG
CCGCCGACGCACAGCACATCGCGGGCGAGTTCGTCTCGCGGCTCAACTACGACCGGCCGCCGGCTGCGGCCGTGGCGCTG
ACCACCGACACCTCGGTGATCACCGCGATCGGCAACGATTACGGCTACGAGCACGTGTTCGAGCGGCAGGTTCTGGCCCT
CGGGCGGCCGGGCGATGTCCTGCTCGCGCTCTCCACGTCGGGGCGGTCGCCGAGCGTGCTGAAGGCGATGGACGCGGCCC
GCGGCCTGGGTCTGCGGGTCGTCGCCTTCACGGGCGCGACGGGCGGGGCGATGCCCGAGCGGGCGGATGTCTGCCTGCAC
GCGCCGTCGGACGCCACGCCGCTGATCCAGCAGATCCACATCACCGCCGCGCACATCGTCTGCGGCCTCGTCGAGGAAAG
CCTGTTCCCGCGCGGGACGGCAGCGTGA

Upstream 100 bases:

>100_bases
GCGGTTCGCCAACGTCTGATCGGGATGGGCGGAGCCTGCAGCGAACGCGCCGCCGGTCGGCCCTACACGGCGGCCGGCGC
GGGAACGGACCGAGGTTATC

Downstream 100 bases:

>100_bases
GGGACGGCCTGTGACCGAGCCAGAGTGGAAGGGTGGAGGCCCCGTCCGGCAAGCCATGATCCTGTGCGGCGGCTTCGGCA
CGCGCCTCGGCGCGCTGACC

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MSAIVDFLTRTRDTFQAALDDTRFHATLAETADLVTASLRGGGKLLTIGNGGSAADAQHIAGEFVSRLNYDRPPAAAVAL
TTDTSVITAIGNDYGYEHVFERQVLALGRPGDVLLALSTSGRSPSVLKAMDAARGLGLRVVAFTGATGGAMPERADVCLH
APSDATPLIQQIHITAAHIVCGLVEESLFPRGTAA

Sequences:

>Translated_195_residues
MSAIVDFLTRTRDTFQAALDDTRFHATLAETADLVTASLRGGGKLLTIGNGGSAADAQHIAGEFVSRLNYDRPPAAAVAL
TTDTSVITAIGNDYGYEHVFERQVLALGRPGDVLLALSTSGRSPSVLKAMDAARGLGLRVVAFTGATGGAMPERADVCLH
APSDATPLIQQIHITAAHIVCGLVEESLFPRGTAA
>Mature_194_residues
SAIVDFLTRTRDTFQAALDDTRFHATLAETADLVTASLRGGGKLLTIGNGGSAADAQHIAGEFVSRLNYDRPPAAAVALT
TDTSVITAIGNDYGYEHVFERQVLALGRPGDVLLALSTSGRSPSVLKAMDAARGLGLRVVAFTGATGGAMPERADVCLHA
PSDATPLIQQIHITAAHIVCGLVEESLFPRGTAA

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1786416, Length=170, Percent_Identity=43.5294117647059, Blast_Score=137, Evalue=3e-34,
Organism=Escherichia coli, GI1789539, Length=158, Percent_Identity=43.0379746835443, Blast_Score=129, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 20255; Mature: 20124

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIVDFLTRTRDTFQAALDDTRFHATLAETADLVTASLRGGGKLLTIGNGGSAADAQHI
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHH
AGEFVSRLNYDRPPAAAVALTTDTSVITAIGNDYGYEHVFERQVLALGRPGDVLLALSTS
HHHHHHHCCCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEECC
GRSPSVLKAMDAARGLGLRVVAFTGATGGAMPERADVCLHAPSDATPLIQQIHITAAHIV
CCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHH
CGLVEESLFPRGTAA
HHHHHHHCCCCCCCC
>Mature Secondary Structure 
SAIVDFLTRTRDTFQAALDDTRFHATLAETADLVTASLRGGGKLLTIGNGGSAADAQHI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHH
AGEFVSRLNYDRPPAAAVALTTDTSVITAIGNDYGYEHVFERQVLALGRPGDVLLALSTS
HHHHHHHCCCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEECC
GRSPSVLKAMDAARGLGLRVVAFTGATGGAMPERADVCLHAPSDATPLIQQIHITAAHIV
CCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHH
CGLVEESLFPRGTAA
HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA