Click here to switch to the map view.

The map label for this gene is fdoG [H]

Identifier: 170747524

GI number: 170747524

Start: 1148675

End: 1151110

Strand: Reverse

Name: fdoG [H]

Synonym: Mrad2831_1092

Alternate gene names: 170747524

Gene position: 1151110-1148675 (Counterclockwise)

Preceding gene: 170747525

Following gene: 170747523

Centisome position: 18.94

GC content: 65.52

Gene sequence:

>2436_bases
ATGACCAACCTCTGGATGGACATCAAGCACGCGGACGTGATCACCGTGATGGGCGGCAATGCCGCCGAGGCGCACCCTTG
CGGCTTCAAGTGGGTCGTGGAGGCGAAGGCCCATAACAATGCCAAGCTGATCGTCGTCGATCCGCGCTTCACCCGCACGG
CGTCGGTGGCCGATCTCTACTGCCCGATCCGGCAGGGGACCGACATCGCGTTCCTGTCGGGCGTGGCCAAGTACCTGCTC
GACAACGACAAGCTGCAGCACCGCTACGTCTCCGCCTACACCAACGCCGGGTACGTGGTCCGCGAGGGCTACGACTTCAG
CGAGGGTCTGTTCGCGGGCTACGACGCGGACAAGCGCGATTACGACAAGACCACCTGGGACTACGAGATCGGCCCCGACG
GCTACGCCGTGGTCGACGAGACGATGCAGCATCCGCGCTGCGTGATGCAGCTCCTGAAGAAGCACGTCTCGCTCTACACG
CCCGAGATGGTCGAGAAGATCTGCGGCTCGCCCAAGGAGACCTTCCTGAAGGTCTGCGAGCTGATGGCGACGACGGCTTC
CCCCGAGAAGTCGATGGCCTCGCTCTACGCGCTCGGCTGGACCCATCACTCCAAGGGCTCGCAGAACATCCGCTCGATGT
GCATCGTGCAGACGCTGCTCGGGAACATCGGCGTGCTCGGCGGCGGCATGCAGGCCCTGCGCGGTCACTCCAACATCCAG
GGGCTGACCGATATCGGGCTGATGTCGAACCTCATCCCCGGGTACCTGAACATCCCGGTGGAGAAGGAGCCCGACTACGC
CAGCTACATCGCCAAGCGGCAGTTCAAGCCGCTGCGGCCCGGACAGACGAGCTACTGGCAGAACTACAACAAGTTCTTCG
TCTCGTTCCAGAAGGCGATGTGGGGCGACAAGGCCACCAAGGAGAACGACTGGGCGTACGACTACCTGCCCAAGCTCGAT
GTGCCGACCTACGACGTGCTGCGCGGGTTCGAGCTCGCCAAGCAGGGCAAGATGACCGGCTACGTCATCCAGGGCTTCAA
CCCCCTGCTGTCGTTCCCGAATCGCGCCAAGATGACGGAAGCCTTCTCCAAGATGAAGTTCATCGTGGTGATGGATCCGC
TCAAGACGGAGACGGCCCGGTTCTGGGAGAACCACGGCGAGTACAACGACGTCGACCCGACCAAGATCCAGACCGAGGTG
TTCGAGCTCCCGACCACCCTGTTCGTGGAGGAGGAAGGCTCGCTGTCGAACTCCAGCCGGTGGCTGCAGTGGCACTGGCA
GGCGCAGGACGCGCCGGGCGAGTGCCGCTCGGACATCGAGATCATGTCGGAGATCTTCCTCCGCATGAAGGCGGCCTACA
AGAAGGACGGCGGGGCCTTCCCGGACCCGATCGTCAATCTGAAGTGGGACTACGCGATCGCCGAGGCACCGACGCCGACC
GAGCTCGCCCGCGAGCTCAACGGCTACACGCTGGCGCCGACGCCGGACCTCAACGGGACCATCATCCCGGCGGGCAAGCA
GGTCGACGGCTTCGCCCAGCTCAAGGACGACGGCACCACCGCCTGCGGCTGCTGGATCTACTCGGGCTGCTACACCGAGA
AGGGCAACATGATGGCCCGCCGGGACAACACCGACCCCGGCGACCGCGGCATCGCGCCGAACTGGGCCTTCGCGTGGCCG
GCCAACCGGCGCGTGCTCTACAACCGCGCCTCGTGCGACCCCGAGGGTCGCCCGTGGTCGGAGAAGAAGAAGCTCATCGA
GTGGAACGGCAAGCAGTGGATCGGCTTCGACGTGCCGGACTACGGCGTCACCGTCGCCCCCGATAAGGGCGTCGGCCCGT
TCATCCTGAACCAGGAGGGCGTCGCCCGCCTGTGGACTCGCGGTCTCATGCGCGACGGGCCGTTCCCGGCGCACTACGAG
CCCTTCGAGTCGCCGGTGGCCAACCTCGCCTTCCCGAAGATCAAGGGCGCGCCCGCGTCCCGCATCTTCAAGGACGATCT
GGCCGATCTCGGCGACGCGAAGGAGTTCCCCTACGCGGCGACGAGCTACCGCCTGACCGAGCACTTCCACGGCTGGACCA
AGCACGCCCGGATCAACGCGATCCTCCAGCCGGAGGCCTTCGTGGAGATCTCGGAGGAGCTCGCCAAGGAGAAGGGCATC
GCCAAGGGCGGCTGGGTCCGCGTCTGGTCGAAGCGCGGCTCGCTCAAGGCCAAGGCGGTGGTGACGAAGCGGATCAAGCC
CCTGATCTGCGACGGCAAGCCCGTCCACGTCGTCGGCATCCCGCAGCACTGGGGCTTCATGGGCCACACCAAGAAAGGAT
GGCACCCGAACTCGCTGACGCCCGTCGTCGGCGACGCGAACACCGAGACGCCGGAGTTCAAGGCCTGGCTCGTGAACATC
GAGCCGACCACGCCTCCGTCGGACGCGGTCGCGTAA

Upstream 100 bases:

>100_bases
GACAGTCCGAAGCATGGGGGCCCTGGTCTTCGATAACCAGGCCAGAGTTTGACACGGTCCGTCGGTCGCCAGTTTGGCGC
CCTCCTTCGGACGCGGTGCG

Downstream 100 bases:

>100_bases
GGGGGAGCGGCAGACATGGCTGACTACAGCTCCCTCGACATCCGCCAGCGCTCCGCCTCCACGGAGACGCCGCCGGAGAT
CCGCCGCCAGGTGGAGGTCG

Product: formate dehydrogenase subunit alpha

Products: NA

Alternate protein names: Aerobic formate dehydrogenase major subunit; FDH-Z subunit alpha; Formate dehydrogenase-O subunit alpha [H]

Number of amino acids: Translated: 811; Mature: 810

Protein sequence:

>811_residues
MTNLWMDIKHADVITVMGGNAAEAHPCGFKWVVEAKAHNNAKLIVVDPRFTRTASVADLYCPIRQGTDIAFLSGVAKYLL
DNDKLQHRYVSAYTNAGYVVREGYDFSEGLFAGYDADKRDYDKTTWDYEIGPDGYAVVDETMQHPRCVMQLLKKHVSLYT
PEMVEKICGSPKETFLKVCELMATTASPEKSMASLYALGWTHHSKGSQNIRSMCIVQTLLGNIGVLGGGMQALRGHSNIQ
GLTDIGLMSNLIPGYLNIPVEKEPDYASYIAKRQFKPLRPGQTSYWQNYNKFFVSFQKAMWGDKATKENDWAYDYLPKLD
VPTYDVLRGFELAKQGKMTGYVIQGFNPLLSFPNRAKMTEAFSKMKFIVVMDPLKTETARFWENHGEYNDVDPTKIQTEV
FELPTTLFVEEEGSLSNSSRWLQWHWQAQDAPGECRSDIEIMSEIFLRMKAAYKKDGGAFPDPIVNLKWDYAIAEAPTPT
ELARELNGYTLAPTPDLNGTIIPAGKQVDGFAQLKDDGTTACGCWIYSGCYTEKGNMMARRDNTDPGDRGIAPNWAFAWP
ANRRVLYNRASCDPEGRPWSEKKKLIEWNGKQWIGFDVPDYGVTVAPDKGVGPFILNQEGVARLWTRGLMRDGPFPAHYE
PFESPVANLAFPKIKGAPASRIFKDDLADLGDAKEFPYAATSYRLTEHFHGWTKHARINAILQPEAFVEISEELAKEKGI
AKGGWVRVWSKRGSLKAKAVVTKRIKPLICDGKPVHVVGIPQHWGFMGHTKKGWHPNSLTPVVGDANTETPEFKAWLVNI
EPTTPPSDAVA

Sequences:

>Translated_811_residues
MTNLWMDIKHADVITVMGGNAAEAHPCGFKWVVEAKAHNNAKLIVVDPRFTRTASVADLYCPIRQGTDIAFLSGVAKYLL
DNDKLQHRYVSAYTNAGYVVREGYDFSEGLFAGYDADKRDYDKTTWDYEIGPDGYAVVDETMQHPRCVMQLLKKHVSLYT
PEMVEKICGSPKETFLKVCELMATTASPEKSMASLYALGWTHHSKGSQNIRSMCIVQTLLGNIGVLGGGMQALRGHSNIQ
GLTDIGLMSNLIPGYLNIPVEKEPDYASYIAKRQFKPLRPGQTSYWQNYNKFFVSFQKAMWGDKATKENDWAYDYLPKLD
VPTYDVLRGFELAKQGKMTGYVIQGFNPLLSFPNRAKMTEAFSKMKFIVVMDPLKTETARFWENHGEYNDVDPTKIQTEV
FELPTTLFVEEEGSLSNSSRWLQWHWQAQDAPGECRSDIEIMSEIFLRMKAAYKKDGGAFPDPIVNLKWDYAIAEAPTPT
ELARELNGYTLAPTPDLNGTIIPAGKQVDGFAQLKDDGTTACGCWIYSGCYTEKGNMMARRDNTDPGDRGIAPNWAFAWP
ANRRVLYNRASCDPEGRPWSEKKKLIEWNGKQWIGFDVPDYGVTVAPDKGVGPFILNQEGVARLWTRGLMRDGPFPAHYE
PFESPVANLAFPKIKGAPASRIFKDDLADLGDAKEFPYAATSYRLTEHFHGWTKHARINAILQPEAFVEISEELAKEKGI
AKGGWVRVWSKRGSLKAKAVVTKRIKPLICDGKPVHVVGIPQHWGFMGHTKKGWHPNSLTPVVGDANTETPEFKAWLVNI
EPTTPPSDAVA
>Mature_810_residues
TNLWMDIKHADVITVMGGNAAEAHPCGFKWVVEAKAHNNAKLIVVDPRFTRTASVADLYCPIRQGTDIAFLSGVAKYLLD
NDKLQHRYVSAYTNAGYVVREGYDFSEGLFAGYDADKRDYDKTTWDYEIGPDGYAVVDETMQHPRCVMQLLKKHVSLYTP
EMVEKICGSPKETFLKVCELMATTASPEKSMASLYALGWTHHSKGSQNIRSMCIVQTLLGNIGVLGGGMQALRGHSNIQG
LTDIGLMSNLIPGYLNIPVEKEPDYASYIAKRQFKPLRPGQTSYWQNYNKFFVSFQKAMWGDKATKENDWAYDYLPKLDV
PTYDVLRGFELAKQGKMTGYVIQGFNPLLSFPNRAKMTEAFSKMKFIVVMDPLKTETARFWENHGEYNDVDPTKIQTEVF
ELPTTLFVEEEGSLSNSSRWLQWHWQAQDAPGECRSDIEIMSEIFLRMKAAYKKDGGAFPDPIVNLKWDYAIAEAPTPTE
LARELNGYTLAPTPDLNGTIIPAGKQVDGFAQLKDDGTTACGCWIYSGCYTEKGNMMARRDNTDPGDRGIAPNWAFAWPA
NRRVLYNRASCDPEGRPWSEKKKLIEWNGKQWIGFDVPDYGVTVAPDKGVGPFILNQEGVARLWTRGLMRDGPFPAHYEP
FESPVANLAFPKIKGAPASRIFKDDLADLGDAKEFPYAATSYRLTEHFHGWTKHARINAILQPEAFVEISEELAKEKGIA
KGGWVRVWSKRGSLKAKAVVTKRIKPLICDGKPVHVVGIPQHWGFMGHTKKGWHPNSLTPVVGDANTETPEFKAWLVNIE
PTTPPSDAVA

Specific function: Allows to use formate as major electron donor during aerobic respiration. Subunit alpha possibly forms the active site [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868720, Length=804, Percent_Identity=59.0796019900497, Blast_Score=1018, Evalue=0.0,
Organism=Escherichia coli, GI3868719, Length=803, Percent_Identity=56.5379825653798, Blast_Score=976, Evalue=0.0,
Organism=Escherichia coli, GI3868721, Length=452, Percent_Identity=24.5575221238938, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI87081797, Length=235, Percent_Identity=26.3829787234043, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1787870, Length=236, Percent_Identity=27.9661016949153, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006443
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 90897; Mature: 90766

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLWMDIKHADVITVMGGNAAEAHPCGFKWVVEAKAHNNAKLIVVDPRFTRTASVADLY
CCCEEEEECCCCEEEEECCCCCCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCHHHHC
CPIRQGTDIAFLSGVAKYLLDNDKLQHRYVSAYTNAGYVVREGYDFSEGLFAGYDADKRD
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCCCCEECCCCCCCC
YDKTTWDYEIGPDGYAVVDETMQHPRCVMQLLKKHVSLYTPEMVEKICGSPKETFLKVCE
CCCCCCCEEECCCCCEEHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHH
LMATTASPEKSMASLYALGWTHHSKGSQNIRSMCIVQTLLGNIGVLGGGMQALRGHSNIQ
HHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCC
GLTDIGLMSNLIPGYLNIPVEKEPDYASYIAKRQFKPLRPGQTSYWQNYNKFFVSFQKAM
CHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
WGDKATKENDWAYDYLPKLDVPTYDVLRGFELAKQGKMTGYVIQGFNPLLSFPNRAKMTE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHCCCCHHHHHH
AFSKMKFIVVMDPLKTETARFWENHGEYNDVDPTKIQTEVFELPTTLFVEEEGSLSNSSR
HHHHEEEEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCC
WLQWHWQAQDAPGECRSDIEIMSEIFLRMKAAYKKDGGAFPDPIVNLKWDYAIAEAPTPT
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECEEECCCCCHH
ELARELNGYTLAPTPDLNGTIIPAGKQVDGFAQLKDDGTTACGCWIYSGCYTEKGNMMAR
HHHHHCCCEEECCCCCCCCEEEECCCCCCCCEEECCCCCCEEEEEEECCEEECCCCEEEE
RDNTDPGDRGIAPNWAFAWPANRRVLYNRASCDPEGRPWSEKKKLIEWNGKQWIGFDVPD
CCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCCCCCCHHHHHHHEEECCCEEEECCCCC
YGVTVAPDKGVGPFILNQEGVARLWTRGLMRDGPFPAHYEPFESPVANLAFPKIKGAPAS
CCEEECCCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCHHCCHHHCCCCCCCCCCHH
RIFKDDLADLGDAKEFPYAATSYRLTEHFHGWTKHARINAILQPEAFVEISEELAKEKGI
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHCCCEEEEEECCHHHHHHHHHHHHHCCC
AKGGWVRVWSKRGSLKAKAVVTKRIKPLICDGKPVHVVGIPQHWGFMGHTKKGWHPNSLT
CCCCEEEEEECCCCCCHHHHHHHCCCEEEECCCEEEEEECCHHCCCCCCCCCCCCCCCCC
PVVGDANTETPEFKAWLVNIEPTTPPSDAVA
CEECCCCCCCCCEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
TNLWMDIKHADVITVMGGNAAEAHPCGFKWVVEAKAHNNAKLIVVDPRFTRTASVADLY
CCEEEEECCCCEEEEECCCCCCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCHHHHC
CPIRQGTDIAFLSGVAKYLLDNDKLQHRYVSAYTNAGYVVREGYDFSEGLFAGYDADKRD
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCCCCEECCCCCCCC
YDKTTWDYEIGPDGYAVVDETMQHPRCVMQLLKKHVSLYTPEMVEKICGSPKETFLKVCE
CCCCCCCEEECCCCCEEHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHH
LMATTASPEKSMASLYALGWTHHSKGSQNIRSMCIVQTLLGNIGVLGGGMQALRGHSNIQ
HHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCC
GLTDIGLMSNLIPGYLNIPVEKEPDYASYIAKRQFKPLRPGQTSYWQNYNKFFVSFQKAM
CHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
WGDKATKENDWAYDYLPKLDVPTYDVLRGFELAKQGKMTGYVIQGFNPLLSFPNRAKMTE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHCCCCHHHHHH
AFSKMKFIVVMDPLKTETARFWENHGEYNDVDPTKIQTEVFELPTTLFVEEEGSLSNSSR
HHHHEEEEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCC
WLQWHWQAQDAPGECRSDIEIMSEIFLRMKAAYKKDGGAFPDPIVNLKWDYAIAEAPTPT
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECEEECCCCCHH
ELARELNGYTLAPTPDLNGTIIPAGKQVDGFAQLKDDGTTACGCWIYSGCYTEKGNMMAR
HHHHHCCCEEECCCCCCCCEEEECCCCCCCCEEECCCCCCEEEEEEECCEEECCCCEEEE
RDNTDPGDRGIAPNWAFAWPANRRVLYNRASCDPEGRPWSEKKKLIEWNGKQWIGFDVPD
CCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCCCCCCHHHHHHHEEECCCEEEECCCCC
YGVTVAPDKGVGPFILNQEGVARLWTRGLMRDGPFPAHYEPFESPVANLAFPKIKGAPAS
CCEEECCCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCHHCCHHHCCCCCCCCCCHH
RIFKDDLADLGDAKEFPYAATSYRLTEHFHGWTKHARINAILQPEAFVEISEELAKEKGI
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHCCCEEEEEECCHHHHHHHHHHHHHCCC
AKGGWVRVWSKRGSLKAKAVVTKRIKPLICDGKPVHVVGIPQHWGFMGHTKKGWHPNSLT
CCCCEEEEEECCCCCCHHHHHHHCCCEEEECCCEEEEEECCHHCCCCCCCCCCCCCCCCC
PVVGDANTETPEFKAWLVNIEPTTPPSDAVA
CEECCCCCCCCCEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503; 8522521 [H]