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The map label for this gene is hcaT [H]

Identifier: 170747274

GI number: 170747274

Start: 882422

End: 883588

Strand: Reverse

Name: hcaT [H]

Synonym: Mrad2831_0841

Alternate gene names: 170747274

Gene position: 883588-882422 (Counterclockwise)

Preceding gene: 170747275

Following gene: 170747273

Centisome position: 14.54

GC content: 78.23

Gene sequence:

>1167_bases
ATGAGGGCCGAGGGGAGCAGCGCGGAACGGCGCGGCGGGCTCGCCCGGTTTCTCGCCCTGTACGCGGCGCTCTACGGCGC
CTACGGCGTCCTGTCGCCGGTGCTGCCGGGCTTCCTCGCCGCGCGCGGTCTGACACCCGGCGAGATCGGTCTCCTCCTCG
CGGCCGCGGGCGCCCTGCGCCTCGGGATCGGGCCCCTGGCCGGCGCCTTCGCCGACCGCCACCGGGCCGGCCGATCCGTC
CTGGCAGCGAGTCTCGCGCTGGCCGGGCTCAGCGCCCTGGCGCACCTGCCCGGCGCCGGGCTGGCGCAATTGATCGGTCC
GGCGCTCCTCTACGCGGCGGGCACCGCGGCCCCGGCGCCCCTCGCCGACGCGCTCGCGCTGGCCGCCGCACGGGGCGGTG
CGGCGTTCCAGTACGGCTGGGTCCGCGGCGCGGGCTCGGCCGCGTTCATCGCCGGCACAGCCGCGGCCGGCTGGCTGATC
GGCCTCTACGGCCTCGCCGCCGCCCTCGTGGCGAGCGGCAGCCTGTTTCTGGCCGCCGGCGCGGCAGCCCTGGCCCTGCC
CGCCGGCCCGGGCGTCGCGGCTCGGGCCGGGGCGCCGTGGCACGGCTTCGCCGCCCTGGTCGCCCTGCCGCGCTTCCGCC
GCACGGTGCTCGTCGCCGGCCTGGTGATCGGCGCGCACGCGATGCACGACGGCTTCGCCATGATCCTGTGGCGGTCCGCC
GGGATCGCGGCGACCACCGCCGGCCTGCTCTGGTCGGTCTCGGTGGCCGCCGAGGTCCTGGTGTTCCTGCTGGTCGGGCC
GCTCCTGCTGGCGCGGATCGGCCCCGCGGCCGGCGTCGCGGTGGCGGCCTGCGCGGGGGCCCTGCGCTGGGCGGTGCTGG
GATCCACGACCGCGATCCCGTGGCTCGCCGCCGCCGAGTCCCTGCACGGGCTGAGCTTCGCCCTCCTGCACCTCGCCTGC
CTGAGGCTCATCGAGGCGTCGACGCCGGCCGATCTCAGGACGACCGCGCTGGCGCTCTACGGGACGCTGGGCCTCGGCCT
CTCAGGGGTCGCGGCGACCCTGGCCTCCGGGGCTCTGTACGGCGCGTTCGGCGCACCGGCCTTCTGGGCCATGGCGGCGC
TGAGTCTCGCGGCCCTGCCGCTCGTGCCGGCGCTGCGGGATCGCTGA

Upstream 100 bases:

>100_bases
GGGACTTTGCTCGAGGACTCGCTCCGGGCGCCGTCGTCCCGGGCAGGCCGTCCCCCGCGCGGAATGACGGGGTGAAGACC
CGTCCGGTGCGAACATCCCG

Downstream 100 bases:

>100_bases
AGCGGCGGGTTCTTTTCCCGCGCCTATGGTACGGACCCGGAACGGACCCGCCCGAAAAGCCCCGCATGCCCGTCGTCGCC
GAGATCCTGATCCCGCTCGC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MRAEGSSAERRGGLARFLALYAALYGAYGVLSPVLPGFLAARGLTPGEIGLLLAAAGALRLGIGPLAGAFADRHRAGRSV
LAASLALAGLSALAHLPGAGLAQLIGPALLYAAGTAAPAPLADALALAAARGGAAFQYGWVRGAGSAAFIAGTAAAGWLI
GLYGLAAALVASGSLFLAAGAAALALPAGPGVAARAGAPWHGFAALVALPRFRRTVLVAGLVIGAHAMHDGFAMILWRSA
GIAATTAGLLWSVSVAAEVLVFLLVGPLLLARIGPAAGVAVAACAGALRWAVLGSTTAIPWLAAAESLHGLSFALLHLAC
LRLIEASTPADLRTTALALYGTLGLGLSGVAATLASGALYGAFGAPAFWAMAALSLAALPLVPALRDR

Sequences:

>Translated_388_residues
MRAEGSSAERRGGLARFLALYAALYGAYGVLSPVLPGFLAARGLTPGEIGLLLAAAGALRLGIGPLAGAFADRHRAGRSV
LAASLALAGLSALAHLPGAGLAQLIGPALLYAAGTAAPAPLADALALAAARGGAAFQYGWVRGAGSAAFIAGTAAAGWLI
GLYGLAAALVASGSLFLAAGAAALALPAGPGVAARAGAPWHGFAALVALPRFRRTVLVAGLVIGAHAMHDGFAMILWRSA
GIAATTAGLLWSVSVAAEVLVFLLVGPLLLARIGPAAGVAVAACAGALRWAVLGSTTAIPWLAAAESLHGLSFALLHLAC
LRLIEASTPADLRTTALALYGTLGLGLSGVAATLASGALYGAFGAPAFWAMAALSLAALPLVPALRDR
>Mature_388_residues
MRAEGSSAERRGGLARFLALYAALYGAYGVLSPVLPGFLAARGLTPGEIGLLLAAAGALRLGIGPLAGAFADRHRAGRSV
LAASLALAGLSALAHLPGAGLAQLIGPALLYAAGTAAPAPLADALALAAARGGAAFQYGWVRGAGSAAFIAGTAAAGWLI
GLYGLAAALVASGSLFLAAGAAALALPAGPGVAARAGAPWHGFAALVALPRFRRTVLVAGLVIGAHAMHDGFAMILWRSA
GIAATTAGLLWSVSVAAEVLVFLLVGPLLLARIGPAAGVAVAACAGALRWAVLGSTTAIPWLAAAESLHGLSFALLHLAC
LRLIEASTPADLRTTALALYGTLGLGLSGVAATLASGALYGAFGAPAFWAMAALSLAALPLVPALRDR

Specific function: Probable permease involved in the uptake of 3- phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=380, Percent_Identity=33.6842105263158, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022814
- InterPro:   IPR016196
- InterPro:   IPR005276 [H]

Pfam domain/function: PF01306 LacY_symp [H]

EC number: NA

Molecular weight: Translated: 38037; Mature: 38037

Theoretical pI: Translated: 11.07; Mature: 11.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAEGSSAERRGGLARFLALYAALYGAYGVLSPVLPGFLAARGLTPGEIGLLLAAAGALR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LGIGPLAGAFADRHRAGRSVLAASLALAGLSALAHLPGAGLAQLIGPALLYAAGTAAPAP
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCH
LADALALAAARGGAAFQYGWVRGAGSAAFIAGTAAAGWLIGLYGLAAALVASGSLFLAAG
HHHHHHHHHHCCCCEEEECCEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC
AAALALPAGPGVAARAGAPWHGFAALVALPRFRRTVLVAGLVIGAHAMHDGFAMILWRSA
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECC
GIAATTAGLLWSVSVAAEVLVFLLVGPLLLARIGPAAGVAVAACAGALRWAVLGSTTAIP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHH
WLAAAESLHGLSFALLHLACLRLIEASTPADLRTTALALYGTLGLGLSGVAATLASGALY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCHH
GAFGAPAFWAMAALSLAALPLVPALRDR
CCCCCHHHHHHHHHHHHHHHHCHHHCCC
>Mature Secondary Structure
MRAEGSSAERRGGLARFLALYAALYGAYGVLSPVLPGFLAARGLTPGEIGLLLAAAGALR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LGIGPLAGAFADRHRAGRSVLAASLALAGLSALAHLPGAGLAQLIGPALLYAAGTAAPAP
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCH
LADALALAAARGGAAFQYGWVRGAGSAAFIAGTAAAGWLIGLYGLAAALVASGSLFLAAG
HHHHHHHHHHCCCCEEEECCEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC
AAALALPAGPGVAARAGAPWHGFAALVALPRFRRTVLVAGLVIGAHAMHDGFAMILWRSA
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECC
GIAATTAGLLWSVSVAAEVLVFLLVGPLLLARIGPAAGVAVAACAGALRWAVLGSTTAIP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHH
WLAAAESLHGLSFALLHLACLRLIEASTPADLRTTALALYGTLGLGLSGVAATLASGALY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCHH
GAFGAPAFWAMAALSLAALPLVPALRDR
CCCCCHHHHHHHHHHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9603882; 9205837; 9278503 [H]