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The map label for this gene is ung [H]

Identifier: 170747167

GI number: 170747167

Start: 772762

End: 773451

Strand: Reverse

Name: ung [H]

Synonym: Mrad2831_0733

Alternate gene names: 170747167

Gene position: 773451-772762 (Counterclockwise)

Preceding gene: 170747170

Following gene: 170747165

Centisome position: 12.73

GC content: 76.23

Gene sequence:

>690_bases
ATGACCGACACGCCCGTCGCCGACGCCCTCACCGCCTTCCGCGCCTCGGGTTCGCCCTGGCTGAGCCTGCCCTTCTTCGC
CGGCGGGGAGGCCGACGCCGTGGCGGCGCGGGTCGATGCGCGAATCGCCGCGGGCGCCCGCGTCCTGCCGGCGCCGGACC
GGATCTTCCGCGCCCTGACAGAGACCCCGCCGCAGGACGTGCGGGCCGTGATCCTCGGCCAGGATCCGTACCCGACCCCG
GGCGACGCCAACGGCCTCGCCTTCTCGTTCGTGGGCTCCGGTCGCCTGCCGGCCTCGCTGAAGGTGATCCTGGCGGAGGC
GGGCTCCGACCGCGCCGCGGGCGGCGACCTGACGCCCTGGGCGCGGCAGGGCGTGCTCCTGCTCAACAGCGCGCTCACCG
TCGAGGCCGGCAAGGCCGGGGCGCATCTGCGTTACGGCTGGGCCGCGCTGACCGACGAGGCGGTGAGCGCCGTGTCGGCG
CGTCCCGAGCCCGCGGTATTCCTGCTCTGGGGGGCCCAGGCGCGGGCCCGGGCCACGCTGATCGACGCGACCCGCCACGG
CGTGTTCGAGAGCGGACACCCCTCGCCGCTCAACCGCGCCCGGGATTTTCCGGGCTCCGACCCGTTCGGGCGGGCCAACC
GGTGGCTCGCCGAGCACGGGCGTCGGCCGATCGAGTGGCGCCTCGGCTGA

Upstream 100 bases:

>100_bases
CCCAGTCCCTAAACACGGGCGGCTCCCGGCCGCAACCGCCGCGCCCGTGACGGTGCTCCCCCGCCCCCTATCTGGCCGCG
GAACCCGACCGCGAGAGACC

Downstream 100 bases:

>100_bases
GGCCGGCGCCGATCCGGTGCGCGGCCGATCACGGCTTGGCGGGCTCGGCGGGCTTCGCAGGCGCGGCCGGCTCCTGGCCC
GCGGGCAGGAGCACGTTCTT

Product: uracil-DNA glycosylase superfamily protein

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MTDTPVADALTAFRASGSPWLSLPFFAGGEADAVAARVDARIAAGARVLPAPDRIFRALTETPPQDVRAVILGQDPYPTP
GDANGLAFSFVGSGRLPASLKVILAEAGSDRAAGGDLTPWARQGVLLLNSALTVEAGKAGAHLRYGWAALTDEAVSAVSA
RPEPAVFLLWGAQARARATLIDATRHGVFESGHPSPLNRARDFPGSDPFGRANRWLAEHGRRPIEWRLG

Sequences:

>Translated_229_residues
MTDTPVADALTAFRASGSPWLSLPFFAGGEADAVAARVDARIAAGARVLPAPDRIFRALTETPPQDVRAVILGQDPYPTP
GDANGLAFSFVGSGRLPASLKVILAEAGSDRAAGGDLTPWARQGVLLLNSALTVEAGKAGAHLRYGWAALTDEAVSAVSA
RPEPAVFLLWGAQARARATLIDATRHGVFESGHPSPLNRARDFPGSDPFGRANRWLAEHGRRPIEWRLG
>Mature_228_residues
TDTPVADALTAFRASGSPWLSLPFFAGGEADAVAARVDARIAAGARVLPAPDRIFRALTETPPQDVRAVILGQDPYPTPG
DANGLAFSFVGSGRLPASLKVILAEAGSDRAAGGDLTPWARQGVLLLNSALTVEAGKAGAHLRYGWAALTDEAVSAVSAR
PEPAVFLLWGAQARARATLIDATRHGVFESGHPSPLNRARDFPGSDPFGRANRWLAEHGRRPIEWRLG

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=185, Percent_Identity=41.6216216216216, Blast_Score=147, Evalue=7e-36,
Organism=Homo sapiens, GI6224979, Length=185, Percent_Identity=41.6216216216216, Blast_Score=147, Evalue=7e-36,
Organism=Escherichia coli, GI1788934, Length=208, Percent_Identity=41.3461538461538, Blast_Score=158, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17556304, Length=219, Percent_Identity=37.8995433789954, Blast_Score=154, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6323620, Length=206, Percent_Identity=37.378640776699, Blast_Score=114, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 24104; Mature: 23973

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTPVADALTAFRASGSPWLSLPFFAGGEADAVAARVDARIAAGARVLPAPDRIFRALT
CCCCCHHHHHHHHHCCCCCCEECCEECCCCCCHHHHHHHHHHHCCCEECCCHHHHHHHHH
ETPPQDVRAVILGQDPYPTPGDANGLAFSFVGSGRLPASLKVILAEAGSDRAAGGDLTPW
CCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCCCCCCHH
ARQGVLLLNSALTVEAGKAGAHLRYGWAALTDEAVSAVSARPEPAVFLLWGAQARARATL
HHCCEEEEECEEEEECCCCCCEEEECHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHEEE
IDATRHGVFESGHPSPLNRARDFPGSDPFGRANRWLAEHGRRPIEWRLG
EHHHHCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure 
TDTPVADALTAFRASGSPWLSLPFFAGGEADAVAARVDARIAAGARVLPAPDRIFRALT
CCCCHHHHHHHHHCCCCCCEECCEECCCCCCHHHHHHHHHHHCCCEECCCHHHHHHHHH
ETPPQDVRAVILGQDPYPTPGDANGLAFSFVGSGRLPASLKVILAEAGSDRAAGGDLTPW
CCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCCCCCCHH
ARQGVLLLNSALTVEAGKAGAHLRYGWAALTDEAVSAVSARPEPAVFLLWGAQARARATL
HHCCEEEEECEEEEECCCCCCEEEECHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHEEE
IDATRHGVFESGHPSPLNRARDFPGSDPFGRANRWLAEHGRRPIEWRLG
EHHHHCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA