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The map label for this gene is plp [H]

Identifier: 170747170

GI number: 170747170

Start: 775115

End: 776050

Strand: Reverse

Name: plp [H]

Synonym: Mrad2831_0736

Alternate gene names: 170747170

Gene position: 776050-775115 (Counterclockwise)

Preceding gene: 170747178

Following gene: 170747167

Centisome position: 12.77

GC content: 69.87

Gene sequence:

>936_bases
ATGCCGAACACCGCCCTTCTCCGGCGCGTCAGCGCGCTCGCCGTCATGATCGCGATGCCGGGACTGGCGCTGGCCCAGGC
ACCCCAGAAGGCCCCGACGCCGGCCGCCAACACGCCGGCGGCCCCCGCCGCGACGCCGGCCGCCGCGACGCCGGCTGCCG
CGCCGAGCGCGGACGCGGTCGTGGCGAGCGTCAATGGCAAGCCGATCACCCAGGGCGACCTCGCCATCGCGGCCGATGAC
CCGGCCCTGTCGCTGCCCGGCGTCGACGAGGCGCAGAAGAAGAACCTGCTCGTCGACTACATGGTCGACCTCCGCGTCGG
TGCGCAGGCCGCCGAGGCCGCCAAGATCGGCGACACGCCGGAGTTCAAGCGCAAGCTCGCCTATTTCCGCGACAAGCTCC
TGCTCGACGACTACCTGGAGCAGGAGGCCAAGCGCGCGGTCACGCCCGAGGCGGAGCACGCGATCTACGACCAGACCGTC
AAGCTGATGAAGCCCGAGGAGGAGGTGCACGCGCGCCACATCCTGGTGGACAACGAGGCCGAGGCCAAGAAGATCGCCGC
GCGCATCAAGGGCGGCGAGGATTTCGCCAAGGTCGCCGCCGAGGCGTCGAAGGACCCGGGCTCGAAGGCCGAGGGCGGCG
ATCTCGGCTGGTTCACCAAGGAGCGGATGGTGCCCGACTTCGCCAACGCCGCCTTCGCGATGAAGGCCGGCCAGGTCTCC
GACCCGATCAAGACCCAGTTCGGCTGGCACGTGATCAAGGTCGAGGAGAAGCGGACCAAGCCGCAGCCGACCTTCGACGA
GCTCAAGGAGCAGATCGACCAGCACCTGATCCGCAAGGCGCAGCAGGACATGATCCTGAAGCTCCGCTCGGAGGCCAAGA
TCGAGCGCGCCGACGCGCCGCCGGCCGCGCAGACTGCGCCCGAACCGAAGAAGTAG

Upstream 100 bases:

>100_bases
CCGCGCTTGCCTTCTCGCCCGACGCGGGCCACCTGTGCCGCGGCGCGACGCCCGGCCGATCCGGCGCGACGCCGAGACGT
GAGCCGAGGACTTCGCCCGT

Downstream 100 bases:

>100_bases
CGCTCGGCGCCCGACCGGCGCGGCCCCCGGGGCCGCGCCCCGTCGTCAGTACGGCCGGTCCGGGACGAGGTAGCTGGACT
GCGCCGGGGCCGGCTGGGGC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase plp; Rotamase plp [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MPNTALLRRVSALAVMIAMPGLALAQAPQKAPTPAANTPAAPAATPAAATPAAAPSADAVVASVNGKPITQGDLAIAADD
PALSLPGVDEAQKKNLLVDYMVDLRVGAQAAEAAKIGDTPEFKRKLAYFRDKLLLDDYLEQEAKRAVTPEAEHAIYDQTV
KLMKPEEEVHARHILVDNEAEAKKIAARIKGGEDFAKVAAEASKDPGSKAEGGDLGWFTKERMVPDFANAAFAMKAGQVS
DPIKTQFGWHVIKVEEKRTKPQPTFDELKEQIDQHLIRKAQQDMILKLRSEAKIERADAPPAAQTAPEPKK

Sequences:

>Translated_311_residues
MPNTALLRRVSALAVMIAMPGLALAQAPQKAPTPAANTPAAPAATPAAATPAAAPSADAVVASVNGKPITQGDLAIAADD
PALSLPGVDEAQKKNLLVDYMVDLRVGAQAAEAAKIGDTPEFKRKLAYFRDKLLLDDYLEQEAKRAVTPEAEHAIYDQTV
KLMKPEEEVHARHILVDNEAEAKKIAARIKGGEDFAKVAAEASKDPGSKAEGGDLGWFTKERMVPDFANAAFAMKAGQVS
DPIKTQFGWHVIKVEEKRTKPQPTFDELKEQIDQHLIRKAQQDMILKLRSEAKIERADAPPAAQTAPEPKK
>Mature_310_residues
PNTALLRRVSALAVMIAMPGLALAQAPQKAPTPAANTPAAPAATPAAATPAAAPSADAVVASVNGKPITQGDLAIAADDP
ALSLPGVDEAQKKNLLVDYMVDLRVGAQAAEAAKIGDTPEFKRKLAYFRDKLLLDDYLEQEAKRAVTPEAEHAIYDQTVK
LMKPEEEVHARHILVDNEAEAKKIAARIKGGEDFAKVAAEASKDPGSKAEGGDLGWFTKERMVPDFANAAFAMKAGQVSD
PIKTQFGWHVIKVEEKRTKPQPTFDELKEQIDQHLIRKAQQDMILKLRSEAKIERADAPPAAQTAPEPKK

Specific function: Assist In The Folding Of Extracytoplasmic Proteins. Essential For The Survival Of E.Coli In Stationary Phase. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Homo sapiens, GI38679892, Length=96, Percent_Identity=37.5, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1786238, Length=102, Percent_Identity=45.0980392156863, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790211, Length=84, Percent_Identity=44.047619047619, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17537235, Length=96, Percent_Identity=41.6666666666667, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356303, Length=96, Percent_Identity=39.5833333333333, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 33386; Mature: 33255

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNTALLRRVSALAVMIAMPGLALAQAPQKAPTPAANTPAAPAATPAAATPAAAPSADAV
CCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
VASVNGKPITQGDLAIAADDPALSLPGVDEAQKKNLLVDYMVDLRVGAQAAEAAKIGDTP
EEECCCCCCCCCCEEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHCCHHHHHHHCCCCH
EFKRKLAYFRDKLLLDDYLEQEAKRAVTPEAEHAIYDQTVKLMKPEEEVHARHILVDNEA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHEEEECCCH
EAKKIAARIKGGEDFAKVAAEASKDPGSKAEGGDLGWFTKERMVPDFANAAFAMKAGQVS
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCC
DPIKTQFGWHVIKVEEKRTKPQPTFDELKEQIDQHLIRKAQQDMILKLRSEAKIERADAP
CCHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PAAQTAPEPKK
CCCCCCCCCCC
>Mature Secondary Structure 
PNTALLRRVSALAVMIAMPGLALAQAPQKAPTPAANTPAAPAATPAAATPAAAPSADAV
CCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
VASVNGKPITQGDLAIAADDPALSLPGVDEAQKKNLLVDYMVDLRVGAQAAEAAKIGDTP
EEECCCCCCCCCCEEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHCCHHHHHHHCCCCH
EFKRKLAYFRDKLLLDDYLEQEAKRAVTPEAEHAIYDQTVKLMKPEEEVHARHILVDNEA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHEEEECCCH
EAKKIAARIKGGEDFAKVAAEASKDPGSKAEGGDLGWFTKERMVPDFANAAFAMKAGQVS
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCC
DPIKTQFGWHVIKVEEKRTKPQPTFDELKEQIDQHLIRKAQQDMILKLRSEAKIERADAP
CCHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PAAQTAPEPKK
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA