Click here to switch to the map view.

The map label for this gene is aer [H]

Identifier: 170682786

GI number: 170682786

Start: 3443548

End: 3445068

Strand: Reverse

Name: aer [H]

Synonym: EcSMS35_3366

Alternate gene names: 170682786

Gene position: 3445068-3443548 (Counterclockwise)

Preceding gene: 170681948

Following gene: 170682681

Centisome position: 67.97

GC content: 54.96

Gene sequence:

>1521_bases
ATGTCTTCTCATCCGTATGTCACCCAGCAAAATACCCCGCTGGCGGACGATACCACTCTGATGTCCACTACCGATCTGCA
AAGCTATATCACTCATGCTAATGACACTTTTGTGCAGGTGAGCGGCTTTACCTTGCAAGAGTTACAAGGGCAGCCGCACA
ACATGGTGCGTCACCCGGATATGCCAAAAGCGGCGTTTGCAGATATGTGGTTCACCCTGAAAAAAGGGGAGCCCTGGAGC
GGCATCGTGAAAAATCGCCGCAAAAATGGCGACCATTATTGGGTGCGGGCCAATGCGGTACCGATGGTGCGCGAGGGAAA
AATCAGTGGCTATATGTCGATTCGTACCCGGGCGACGGATGAAGAGATCGCGGCGGTGGAGCCGCTGTACAAAGCGTTGA
ACGCCGGACGTACCAGTAAGCGTATTCATAAAGGCCTGGTGGTGCGTAAAGGCTGGCTGGGAAAACTGCCTTCATTACCG
CTTCGCTGGCGGGCGCGTGGCGTGATGACCCTGATGTTTATCTTGCTGGCGGTCATGCTTTGGTTTGTTGCTGCCCCGGT
GGTGACGTATATCCTCTGTGCGTTAGTGGTATTGTTGGCAAGCGCCTGTTTTGAATGGCAGATTGTCCGCCCGATAGAAA
ATGTCGCCCGTCAGGCACTGAAGGTGGCGACCGGAGAGCGTAATAGTGTTGAGCATCTGAATCGCAGCGATGAGCTGGGG
CTGACATTACGCGCGGTAGGGCAGCTTGGCCTGATGTGCCGTTGGCTAATTAACGATGTCTCAAGCCAGGTGTCCAGTGT
CAGAAATGGCAGTGAGACGCTGGCGAAAGGCACCGATGAACTGAACGAACATACCCAGCAGACAGTTGATAACGTTCAGC
AAACGGTGGCGACCATGAACCAGATGGCGGCGTCGGTGAAACAGAACTCTGCCACGGCGTCGGCTGCTGATAAACTTTCT
ATCACCGCCAGTAATGCGGCAGTGCAGGGCGGGGAGGCGATGACTACGGTGATCAAGACAATGGACGATATTGCCGACAG
TACCCAGCGCATTGGCACCATTACTTCGCTGATTAACGATATTGCGTTTCAGACCAATATTCTGGCCCTGAATGCGGCGG
TGGAAGCGGCGCGTGCCGGCGAACAGGGCAAAGGTTTTGCAGTGGTGGCGGGGGAAGTGCGTCATTTAGCCAGCCGCAGC
GCCAATGCTGCCAACGATATTCGCAAGCTGATTGATGCCAGTGCTGATAAGGTGCAATCTGGTTCGCAGCAGGTACACGC
CGCCGGACGGACGATGGAAGATATTGTGGCGCAGGTAAAAAACGTCACCCAGTTGATAGCTCAGATTAGCCATTCAACGC
TGGAACAGGCCGATGGGCTTTCCAGCCTGACCCGTGCAGTGGATGAGCTTAACCTGATCACCCAGAAAAACGCCGAGTTA
GTGGAAGAGAGTGCGCAGGTGTCGGCGATGGTGAAACACCGCGCCAGCCGACTGGAAGACGCGGTGACGGTGCTGCATTA
A

Upstream 100 bases:

>100_bases
GCGATCTAAATCAAATTAATCAGTTAAAGATAACCGCAGTGGGGCCGACATAAACTCTGACAAGAAGTTAACAACCATAT
AACCTGCACAGGACGCGAAC

Downstream 100 bases:

>100_bases
TCGGTATGCCGGATCCGGCAATCGGTGATTAATCCAGTTGCGTAATATCAAAAGCGGCGCGGTCGATCACCGCAATGATC
TTTTTTATTTGTGCATCAGT

Product: aerotaxis receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGFTLQELQGQPHNMVRHPDMPKAAFADMWFTLKKGEPWS
GIVKNRRKNGDHYWVRANAVPMVREGKISGYMSIRTRATDEEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLP
LRWRARGVMTLMFILLAVMLWFVAAPVVTYILCALVVLLASACFEWQIVRPIENVARQALKVATGERNSVEHLNRSDELG
LTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAKGTDELNEHTQQTVDNVQQTVATMNQMAASVKQNSATASAADKLS
ITASNAAVQGGEAMTTVIKTMDDIADSTQRIGTITSLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRS
ANAANDIRKLIDASADKVQSGSQQVHAAGRTMEDIVAQVKNVTQLIAQISHSTLEQADGLSSLTRAVDELNLITQKNAEL
VEESAQVSAMVKHRASRLEDAVTVLH

Sequences:

>Translated_506_residues
MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGFTLQELQGQPHNMVRHPDMPKAAFADMWFTLKKGEPWS
GIVKNRRKNGDHYWVRANAVPMVREGKISGYMSIRTRATDEEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLP
LRWRARGVMTLMFILLAVMLWFVAAPVVTYILCALVVLLASACFEWQIVRPIENVARQALKVATGERNSVEHLNRSDELG
LTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAKGTDELNEHTQQTVDNVQQTVATMNQMAASVKQNSATASAADKLS
ITASNAAVQGGEAMTTVIKTMDDIADSTQRIGTITSLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRS
ANAANDIRKLIDASADKVQSGSQQVHAAGRTMEDIVAQVKNVTQLIAQISHSTLEQADGLSSLTRAVDELNLITQKNAEL
VEESAQVSAMVKHRASRLEDAVTVLH
>Mature_505_residues
SSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGFTLQELQGQPHNMVRHPDMPKAAFADMWFTLKKGEPWSG
IVKNRRKNGDHYWVRANAVPMVREGKISGYMSIRTRATDEEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLPL
RWRARGVMTLMFILLAVMLWFVAAPVVTYILCALVVLLASACFEWQIVRPIENVARQALKVATGERNSVEHLNRSDELGL
TLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAKGTDELNEHTQQTVDNVQQTVATMNQMAASVKQNSATASAADKLSI
TASNAAVQGGEAMTTVIKTMDDIADSTQRIGTITSLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRSA
NAANDIRKLIDASADKVQSGSQQVHAAGRTMEDIVAQVKNVTQLIAQISHSTLEQADGLSSLTRAVDELNLITQKNAELV
EESAQVSAMVKHRASRLEDAVTVLH

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=506, Percent_Identity=99.4071146245059, Blast_Score=1035, Evalue=0.0,
Organism=Escherichia coli, GI1787690, Length=323, Percent_Identity=39.938080495356, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1788195, Length=267, Percent_Identity=46.0674157303371, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI2367378, Length=324, Percent_Identity=40.7407407407407, Blast_Score=201, Evalue=6e-53,
Organism=Escherichia coli, GI1788194, Length=249, Percent_Identity=46.1847389558233, Blast_Score=199, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 55098; Mature: 54966

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGFTLQELQGQPHNMVRHPD
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHCCCCCCCCCCCC
MPKAAFADMWFTLKKGEPWSGIVKNRRKNGDHYWVRANAVPMVREGKISGYMSIRTRATD
CCHHHHHHHHEEEECCCCCHHHHHHHCCCCCEEEEEECCCCCEECCCCCCEEEEEECCCC
EEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLPLRWRARGVMTLMFILLAVML
HHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
WFVAAPVVTYILCALVVLLASACFEWQIVRPIENVARQALKVATGERNSVEHLNRSDELG
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCC
LTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAKGTDELNEHTQQTVDNVQQTVATMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
QMAASVKQNSATASAADKLSITASNAAVQGGEAMTTVIKTMDDIADSTQRIGTITSLIND
HHHHHHHHCCCHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRSANAANDIRKLIDASADKVQS
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHC
GSQQVHAAGRTMEDIVAQVKNVTQLIAQISHSTLEQADGLSSLTRAVDELNLITQKNAEL
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHH
VEESAQVSAMVKHRASRLEDAVTVLH
HHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGFTLQELQGQPHNMVRHPD
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHCCCCCCCCCCCC
MPKAAFADMWFTLKKGEPWSGIVKNRRKNGDHYWVRANAVPMVREGKISGYMSIRTRATD
CCHHHHHHHHEEEECCCCCHHHHHHHCCCCCEEEEEECCCCCEECCCCCCEEEEEECCCC
EEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLPLRWRARGVMTLMFILLAVML
HHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
WFVAAPVVTYILCALVVLLASACFEWQIVRPIENVARQALKVATGERNSVEHLNRSDELG
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCC
LTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAKGTDELNEHTQQTVDNVQQTVATMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
QMAASVKQNSATASAADKLSITASNAAVQGGEAMTTVIKTMDDIADSTQRIGTITSLIND
HHHHHHHHCCCHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRSANAANDIRKLIDASADKVQS
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHC
GSQQVHAAGRTMEDIVAQVKNVTQLIAQISHSTLEQADGLSSLTRAVDELNLITQKNAEL
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHH
VEESAQVSAMVKHRASRLEDAVTVLH
HHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]