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The map label for this gene is malG

Identifier: 170680586

GI number: 170680586

Start: 4590176

End: 4591066

Strand: Reverse

Name: malG

Synonym: EcSMS35_4494

Alternate gene names: 170680586

Gene position: 4591066-4590176 (Counterclockwise)

Preceding gene: 170684307

Following gene: 170681775

Centisome position: 90.58

GC content: 55.11

Gene sequence:

>891_bases
ATGGCAATGGTCCAACCGAAATCGCAAAAAGCACGTTTGTTTATTACTCACCTGCTACTGCTACTTTTTATCGCGGCGAT
TATGTTCCCGCTGCTGATGGTCGTCGCCATCTCGCTGCGTCAGGGGAACTTCGCGACTGGCAGCCTGATCCCGGAGCAAA
TCTCCTGGGATCACTGGAAACTGGCGTTAGGTTTTAGTGTGGAACAGGCTGATGGTCGCATTACGCCACCGCCATTCCCG
GTACTGCTGTGGCTGTGGAACTCGGTAAAGGTCGCCGGGATTTCCGCGATTGGCATTGTGGCGCTCTCCACCACCTGCGC
CTACGCTTTCGCCCGTATGCGCTTTCCAGGCAAAGCGACGCTGCTGAAAGGAATGCTGATTTTCCAGATGTTCCCGGCAG
TACTTTCACTGGTCGCGTTGTATGCGTTGTTTGATCGTCTGGGTGAGTACATTCCATTCATTGGTCTGAATACTCACGGC
GGCGTAATTTTCGCGTATCTGGGCGGGATTGCGCTGCATGTCTGGACCATCAAAGGTTATTTCGAAACCATCGACAGTTC
GCTGGAAGAAGCGGCGGCGCTGGATGGTGCGACACCGTGGCAGGCCTTCCGCCTTGTCCTGTTGCCGCTGTCAGTACCGA
TTCTGGCGGTGGTGTTCATCCTGTCGTTTATCGCTGCCATTACTGAAGTTCCGGTCGCGTCGCTATTACTGCGTGACGTA
AACAGCTACACCCTGGCTGTGGGGATGCAGCAATACCTCAACCCGCAAAACTACCTGTGGGGTGACTTTGCCGCCGCTGC
CGTGATGTCTGCATTACCGATCACCATCGTCTTCCTGCTGGCTCAACGCTGGCTGGTCAACGGCCTGACGGCAGGTGGTG
TGAAAGGTTAA

Upstream 100 bases:

>100_bases
CAGCAGCAATTGCCACGCTGATCTTCCTGCTGGTGGGTGCGCTGGCGATAGTGAACCTGAAAGCCACGCGAATGAAGTTT
GATTAAGGGAGATAACAAAA

Downstream 100 bases:

>100_bases
AGATGTTGTTCTGCCAATGTTATGCCGCTGCACCCTCAACTTACGTTATCCCAACTTGTGACTGTTATTCGGCGCTCCAC
GGAGCGCCTTTTTTTACTCC

Product: maltose transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MAMVQPKSQKARLFITHLLLLLFIAAIMFPLLMVVAISLRQGNFATGSLIPEQISWDHWKLALGFSVEQADGRITPPPFP
VLLWLWNSVKVAGISAIGIVALSTTCAYAFARMRFPGKATLLKGMLIFQMFPAVLSLVALYALFDRLGEYIPFIGLNTHG
GVIFAYLGGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDV
NSYTLAVGMQQYLNPQNYLWGDFAAAAVMSALPITIVFLLAQRWLVNGLTAGGVKG

Sequences:

>Translated_296_residues
MAMVQPKSQKARLFITHLLLLLFIAAIMFPLLMVVAISLRQGNFATGSLIPEQISWDHWKLALGFSVEQADGRITPPPFP
VLLWLWNSVKVAGISAIGIVALSTTCAYAFARMRFPGKATLLKGMLIFQMFPAVLSLVALYALFDRLGEYIPFIGLNTHG
GVIFAYLGGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDV
NSYTLAVGMQQYLNPQNYLWGDFAAAAVMSALPITIVFLLAQRWLVNGLTAGGVKG
>Mature_295_residues
AMVQPKSQKARLFITHLLLLLFIAAIMFPLLMVVAISLRQGNFATGSLIPEQISWDHWKLALGFSVEQADGRITPPPFPV
LLWLWNSVKVAGISAIGIVALSTTCAYAFARMRFPGKATLLKGMLIFQMFPAVLSLVALYALFDRLGEYIPFIGLNTHGG
VIFAYLGGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVN
SYTLAVGMQQYLNPQNYLWGDFAAAAVMSALPITIVFLLAQRWLVNGLTAGGVKG

Specific function: Part of the binding-protein-dependent transport system for maltose; probably responsible for the translocation of the substrate across the membrane

COG id: COG3833

COG function: function code G; ABC-type maltose transport systems, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1790464, Length=296, Percent_Identity=100, Blast_Score=588, Evalue=1e-169,
Organism=Escherichia coli, GI1787571, Length=280, Percent_Identity=30.3571428571429, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789860, Length=284, Percent_Identity=25.7042253521127, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MALG_ECO57 (P68185)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   C86096
- PIR:   G91255
- RefSeq:   NP_290666.1
- RefSeq:   NP_313042.1
- ProteinModelPortal:   P68185
- SMR:   P68185
- EnsemblBacteria:   EBESCT00000024399
- EnsemblBacteria:   EBESCT00000055306
- GeneID:   914319
- GeneID:   960091
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z5630
- KEGG:   ecs:ECs5015
- GeneTree:   EBGT00050000008925
- HOGENOM:   HBG729451
- OMA:   IIAISFR
- ProtClustDB:   PRK10998
- BioCyc:   ECOL83334:ECS5015-MONOMER
- InterPro:   IPR000515

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 32226; Mature: 32095

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1e41381c)-; HASH(0x1db915b8)-; HASH(0x1d762a78)-; HASH(0x1e251fdc)-; HASH(0x1e4005a0)-; HASH(0x1e2b2c5c)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMVQPKSQKARLFITHLLLLLFIAAIMFPLLMVVAISLRQGNFATGSLIPEQISWDHWK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCEE
LALGFSVEQADGRITPPPFPVLLWLWNSVKVAGISAIGIVALSTTCAYAFARMRFPGKAT
EEEECEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LLKGMLIFQMFPAVLSLVALYALFDRLGEYIPFIGLNTHGGVIFAYLGGIALHVWTIKGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
FETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSYTLAVGMQQYLNPQNYLWGDFAAAAVMSALPITIVFLLAQRWLVNGLTAGGVKG
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
>Mature Secondary Structure 
AMVQPKSQKARLFITHLLLLLFIAAIMFPLLMVVAISLRQGNFATGSLIPEQISWDHWK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCEE
LALGFSVEQADGRITPPPFPVLLWLWNSVKVAGISAIGIVALSTTCAYAFARMRFPGKAT
EEEECEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LLKGMLIFQMFPAVLSLVALYALFDRLGEYIPFIGLNTHGGVIFAYLGGIALHVWTIKGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
FETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSYTLAVGMQQYLNPQNYLWGDFAAAAVMSALPITIVFLLAQRWLVNGLTAGGVKG
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796