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The map label for this gene is malF [H]

Identifier: 170684307

GI number: 170684307

Start: 4591081

End: 4592625

Strand: Reverse

Name: malF [H]

Synonym: EcSMS35_4495

Alternate gene names: 170684307

Gene position: 4592625-4591081 (Counterclockwise)

Preceding gene: 170679620

Following gene: 170680586

Centisome position: 90.61

GC content: 52.94

Gene sequence:

>1545_bases
ATGGATGTCATTAAAAAGAAACATTGGTGGCAAAGCGACGCGCTGAAATGGTCAGTGTTAGGTCTGCTCGGCCTGCTGGT
GGGTTACCTTGTTGTTTTAATGTACGCACAAGGGGAATACCTGTTCGCCATTACCACGCTGATATTGAGTTCAGCGGGGC
TGTATATTTTCGCCAATCGTAAAGCCTACGCCTGGCGCTATGTTTACCCGGGAATGGCTGGAATGGGATTATTCGTCCTC
TTCCCTTTGGTCTGCACCATCGCCATTGCCTTTACCAACTACAGCAGCACTAACCAGCTGACTTTTGAACGTGCGCAGGA
AGTGTTGTTAGATCGCTCCTGGCAAGCAGGCAAAACCTATAATTTTGGTCTTTACCCGGCGGGCGATGAGTGGCAACTGG
CGCTCAGCGACGGCGAAACCGGCAAAAATTACCTCTCCGACGCGTTTAAATTTGGCGGCGAGCAAAAACTGCAACTGAAA
GAAACGACCGCCCAGCCCGAAGGCGAACGCGCGAATCTGCGCGTGATTACCCAGAATCGTCAGGCACTGAGTGACATTAC
CGCCATTCTGCCGGATGGCAACAAAGTGATGATGAGCTCCCTGCGCCAGTTTTCTGGCACGCAGCCGCTCTACACACTCG
ACGGTGACGGCACGCTGACGAATAATCAGAGCGGCGTAAAATATCGTCCAAACGACCAGATTGGTTTTTACCAGTCCATC
ACTGCTGACGGCAACTGGGGTGATGAAAAGCTAAGCCCCGGTTACACCGTGACCACCGGCTGGAAAAACTTTACCCGCGT
CTTTACCGACGAAGGCATTCAGAAACCGTTCCTCGCCATTTTCGTCTGGACCGTGGTGTTCTCGCTGATCACTGTCTTTT
TAACGGTGGCGGTCGGCATGGTTCTGGCGTGTCTGGTGCAGTGGGAAGCGTTGCGCGGCAAAGCGGTCTATCGCGTCCTG
CTTATTCTGCCCTACGCGGTGCCATCGTTCATTTCAATCTTGATTTTCAAAGGGTTGTTTAACCAGAGCTTCGGTGAGAT
CAACATGATGTTGAGCGCGCTGTTTGGCGTGAAGCCCGCCTGGTTCAGCGATCCGACCACCGCCCGAACGATGCTGATTA
TCGTCAATACCTGGCTGGGTTATCCGTACATGATGATCCTCTGCATGGGCTTGCTGAAAGCGATTCCGGACGATTTGTAT
GAAGCCTCAGCAATGGATGGCGCAGGTCCGTTCCAGAACTTCTTTAAGATTACGCTGCCGCTGCTGATTAAACCGCTGAC
GCCGCTGATGATCGCCAGCTTCGCCTTTAACTTTAACAACTTCGTGCTGATTCAACTGTTAACCAACGGCGGCCCGGATC
GTCTTGGCACGACCACGCCAGCCGGTTATACCGACCTGCTTGTTAACTACACCTACCGCATCGCTTTTGAAGGCGGCGGG
GGTCAGGACTTCGGTCTGGCAGCAGCAATTGCCACGCTGATCTTCCTGCTGGTGGGTGCGCTGGCGATAGTGAACCTGAA
AGCCACGCGAATGAAGTTTGATTAA

Upstream 100 bases:

>100_bases
AACGTATGTAGGCCTGGTAAGGCGCGTCAGCGTCGCATCAGGCAGTTGTTGTCGGATAAGGCGTGAAAGCCTTATCCGTC
CTGGAATGAGGAAGAACCCC

Downstream 100 bases:

>100_bases
GGGAGATAACAAAAATGGCAATGGTCCAACCGAAATCGCAAAAAGCACGTTTGTTTATTACTCACCTGCTACTGCTACTT
TTTATCGCGGCGATTATGTT

Product: maltose transporter membrane protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MDVIKKKHWWQSDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAITTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVL
FPLVCTIAIAFTNYSSTNQLTFERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLK
ETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGTLTNNQSGVKYRPNDQIGFYQSI
TADGNWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKPFLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVL
LILPYAVPSFISILIFKGLFNQSFGEINMMLSALFGVKPAWFSDPTTARTMLIIVNTWLGYPYMMILCMGLLKAIPDDLY
EASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDRLGTTTPAGYTDLLVNYTYRIAFEGGG
GQDFGLAAAIATLIFLLVGALAIVNLKATRMKFD

Sequences:

>Translated_514_residues
MDVIKKKHWWQSDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAITTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVL
FPLVCTIAIAFTNYSSTNQLTFERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLK
ETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGTLTNNQSGVKYRPNDQIGFYQSI
TADGNWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKPFLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVL
LILPYAVPSFISILIFKGLFNQSFGEINMMLSALFGVKPAWFSDPTTARTMLIIVNTWLGYPYMMILCMGLLKAIPDDLY
EASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDRLGTTTPAGYTDLLVNYTYRIAFEGGG
GQDFGLAAAIATLIFLLVGALAIVNLKATRMKFD
>Mature_514_residues
MDVIKKKHWWQSDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAITTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVL
FPLVCTIAIAFTNYSSTNQLTFERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLK
ETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGTLTNNQSGVKYRPNDQIGFYQSI
TADGNWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKPFLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVL
LILPYAVPSFISILIFKGLFNQSFGEINMMLSALFGVKPAWFSDPTTARTMLIIVNTWLGYPYMMILCMGLLKAIPDDLY
EASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDRLGTTTPAGYTDLLVNYTYRIAFEGGG
GQDFGLAAAIATLIFLLVGALAIVNLKATRMKFD

Specific function: Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790465, Length=514, Percent_Identity=99.8054474708171, Blast_Score=1041, Evalue=0.0,
Organism=Escherichia coli, GI1787570, Length=267, Percent_Identity=27.7153558052434, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1789861, Length=262, Percent_Identity=31.6793893129771, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 57015; Mature: 57015

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVIKKKHWWQSDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAITTLILSSAGLYIFANR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECC
KAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTFERAQEVLLDRSWQAGKTY
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCEE
NFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLKETTAQPEGERANLRVITQNR
CCCEECCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEEECCH
QALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGTLTNNQSGVKYRPNDQIGFYQSI
HHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEECCCCEECCCCCCCEECCCCCCCCEEEE
TADGNWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKPFLAIFVWTVVFSLITVFLTVAVGM
CCCCCCCCCCCCCCEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLACLVQWEALRGKAVYRVLLILPYAVPSFISILIFKGLFNQSFGEINMMLSALFGVKPA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
WFSDPTTARTMLIIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPFQNFFKITLP
CCCCCCCHHEEEEEEEHHHCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHH
LLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDRLGTTTPAGYTDLLVNYTYRIAFEGGG
HHHCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHEEEEEEEEEECCC
GQDFGLAAAIATLIFLLVGALAIVNLKATRMKFD
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCC
>Mature Secondary Structure
MDVIKKKHWWQSDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAITTLILSSAGLYIFANR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECC
KAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTFERAQEVLLDRSWQAGKTY
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCEE
NFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLKETTAQPEGERANLRVITQNR
CCCEECCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEEECCH
QALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGTLTNNQSGVKYRPNDQIGFYQSI
HHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEECCCCEECCCCCCCEECCCCCCCCEEEE
TADGNWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKPFLAIFVWTVVFSLITVFLTVAVGM
CCCCCCCCCCCCCCEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLACLVQWEALRGKAVYRVLLILPYAVPSFISILIFKGLFNQSFGEINMMLSALFGVKPA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
WFSDPTTARTMLIIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPFQNFFKITLP
CCCCCCCHHEEEEEEEHHHCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHH
LLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDRLGTTTPAGYTDLLVNYTYRIAFEGGG
HHHCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHEEEEEEEEEECCC
GQDFGLAAAIATLIFLLVGALAIVNLKATRMKFD
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]