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The map label for this gene is lpfA [H]

Identifier: 170680528

GI number: 170680528

Start: 4190762

End: 4191334

Strand: Reverse

Name: lpfA [H]

Synonym: EcSMS35_4096

Alternate gene names: 170680528

Gene position: 4191334-4190762 (Counterclockwise)

Preceding gene: 170681402

Following gene: 170681205

Centisome position: 82.7

GC content: 48.87

Gene sequence:

>573_bases
ATGAAGCGTAATATTATAGGCGGTGCATTCACTCTGGCATCTTTAATGCTGGCCGGACATGCACTGGCAGAAGATGGTGT
TGTTCACTTCGTCGGTGAAATTGTCGACACTACTTGTGAAGTTACCTCCGATACAGCCGATCAAACCGTCCCACTGGGTA
AAGTCAGTAAAAATGCATTTTCAGGTGTAGGTAGTCTGGCGTCACCACAGCAGTTCAGTATTAAACTTGAAAAGTGCCCG
GCAACCTACACTCAGGCAGCCGTTCGTTTTGATGGTACAGAAGCGCCTGGCGGCGACGGCGACCTGAAAGTGGGTACGCC
GCTTACAGCGGGCAACCCTGGCGATTTTACCGGTACAGGACAAGCGATTGCGGCAACGGGTGTCGGTATTCGTATTTTTA
ACCAGTCAGATAACTCGCAGGTTAAACTTTATAACGATTCTGCCTATACCGCTATCGACGCGGAAGGCAAGGCTGAAATG
AAGTTTATTGCACGCTATGTGGCAACCAATGCAACCGTAACGGCGGGTACGGCGAACGCCGATTCACAATTTACTGTCGA
ATATAAGAAATAA

Upstream 100 bases:

>100_bases
AAAACTATCTCATTGGTGTACTATGCCTGTGAATCAAAGCACACTTATTATTTTAAGTGATGATTCATGGTAAAGGATAT
ATTATATCAATGGAGTTTTT

Downstream 100 bases:

>100_bases
TTTATCAAGGGCCTTTTTATTCAGTTGGCTTTGGCCAGGGAGTCGTTATGTCCAGAAAAAGTTGTTTAATCAGGCTCTTT
AAAACAACCGTTTCATGTAA

Product: long polar fimbrial operon protein LpfA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MKRNIIGGAFTLASLMLAGHALAEDGVVHFVGEIVDTTCEVTSDTADQTVPLGKVSKNAFSGVGSLASPQQFSIKLEKCP
ATYTQAAVRFDGTEAPGGDGDLKVGTPLTAGNPGDFTGTGQAIAATGVGIRIFNQSDNSQVKLYNDSAYTAIDAEGKAEM
KFIARYVATNATVTAGTANADSQFTVEYKK

Sequences:

>Translated_190_residues
MKRNIIGGAFTLASLMLAGHALAEDGVVHFVGEIVDTTCEVTSDTADQTVPLGKVSKNAFSGVGSLASPQQFSIKLEKCP
ATYTQAAVRFDGTEAPGGDGDLKVGTPLTAGNPGDFTGTGQAIAATGVGIRIFNQSDNSQVKLYNDSAYTAIDAEGKAEM
KFIARYVATNATVTAGTANADSQFTVEYKK
>Mature_190_residues
MKRNIIGGAFTLASLMLAGHALAEDGVVHFVGEIVDTTCEVTSDTADQTVPLGKVSKNAFSGVGSLASPQQFSIKLEKCP
ATYTQAAVRFDGTEAPGGDGDLKVGTPLTAGNPGDFTGTGQAIAATGVGIRIFNQSDNSQVKLYNDSAYTAIDAEGKAEM
KFIARYVATNATVTAGTANADSQFTVEYKK

Specific function: Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial protein family [H]

Homologues:

Organism=Escherichia coli, GI87082421, Length=198, Percent_Identity=31.3131313131313, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI87081753, Length=173, Percent_Identity=32.3699421965318, Blast_Score=70, Evalue=6e-14,
Organism=Escherichia coli, GI1789531, Length=193, Percent_Identity=31.0880829015544, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790773, Length=181, Percent_Identity=28.7292817679558, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1786746, Length=162, Percent_Identity=31.4814814814815, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008966
- InterPro:   IPR000259
- InterPro:   IPR014779 [H]

Pfam domain/function: PF00419 Fimbrial [H]

EC number: NA

Molecular weight: Translated: 19665; Mature: 19665

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRNIIGGAFTLASLMLAGHALAEDGVVHFVGEIVDTTCEVTSDTADQTVPLGKVSKNAF
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCEEECCCCCCCCCCCCCHHCCHHH
SGVGSLASPQQFSIKLEKCPATYTQAAVRFDGTEAPGGDGDLKVGTPLTAGNPGDFTGTG
HCCCCCCCCCEEEEEEECCCCCHHEEEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCC
QAIAATGVGIRIFNQSDNSQVKLYNDSAYTAIDAEGKAEMKFIARYVATNATVTAGTANA
CEEEECCCEEEEEECCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHCCCEEEECCCCC
DSQFTVEYKK
CCEEEEEECC
>Mature Secondary Structure
MKRNIIGGAFTLASLMLAGHALAEDGVVHFVGEIVDTTCEVTSDTADQTVPLGKVSKNAF
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCEEECCCCCCCCCCCCCHHCCHHH
SGVGSLASPQQFSIKLEKCPATYTQAAVRFDGTEAPGGDGDLKVGTPLTAGNPGDFTGTG
HCCCCCCCCCEEEEEEECCCCCHHEEEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCC
QAIAATGVGIRIFNQSDNSQVKLYNDSAYTAIDAEGKAEMKFIARYVATNATVTAGTANA
CEEEECCCEEEEEECCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHCCCEEEECCCCC
DSQFTVEYKK
CCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1982455 [H]