Click here to switch to the map view.

The map label for this gene is yhaO

Identifier: 170679999

GI number: 170679999

Start: 3486907

End: 3488238

Strand: Reverse

Name: yhaO

Synonym: EcSMS35_3407

Alternate gene names: 170679999

Gene position: 3488238-3486907 (Counterclockwise)

Preceding gene: 170680456

Following gene: 170681817

Centisome position: 68.82

GC content: 50.68

Gene sequence:

>1332_bases
ATGGAAATTGCATCGAATAAAGGCGTCATTGCAGACGCTTCGACCCCGGCGGGTCGTGCTGGAATGAGTGAGAGCGAGTG
GCGAGAAGCGATCAAATTCGACAGTACTGACACCGGCTGGGTGATTATGAGTATCGGGATGGCGATTGGCGCGGGGATTG
TTTTTCTCCCGGTGCAGGTCGGTTTGATGGGGTTGTGGGTATTTTTGCTCTCATCGGTGATTGGTTACCCGGCAATGTAT
CTGTTTCAGCGGTTGTTTATTAATACGTTGGCAGAATCACCAGAATGTAAAGATTACCCGAGCGTCATTAGCGGTTATTT
AGGTAAAAACTGGGGCATCCTGTTAGGTGCACTCTATTTCGTAATGCTGGTGATTTGGATGTTCGTCTATTCCACCGCCA
TCACCAACGATAGTGCTTCCTACCTGCATACCTTCGGCGTGACGGAAGGGTTGCTGTCAGACAGTCCCTTTTATGGTCTG
GTACTGATTTGCATTCTGGTGGCGATCTCTTCACGCGGCGAGAAATTGTTATTCAAAATTTCGACCGGCATGGTGCTGAC
CAAGCTGCTGGTGGTCGCGGCGCTGGGCGTATCGATGGTGGGAATGTGGCATCTGTATAACGTCGGTTCGCTACCGCCGC
TGGGGCTGCTGGTGAAAAACGCCATTATTACGCTGCCGTTTACCCTGACGTCGATTCTGTTTATCCAGACGTTAAGCCCG
ATGGTGATCTCTTATCGCTCGCGGGAAAAATCGATTGAAGTGGCGCGGCATAAAGCATTGCGGGCAATGAATATCGCGTT
TGGCATTTTGTTTGTCACCGTCTTTTTCTACGCAGTGTCGTTCACGCTGGCGATGGGACATGACGAAGCGGTAAAAGCCT
ACGAGCAGAATATTTCCGCGCTGGCGATTGCGGCGCAGTTTATTAGCGGTGACGGCGCAGCGTGGGTGAAAGTGGTCAGC
GTCATTCTCAATATCTTTGCAGTAATGACCGCGTTTTTTGGCGTCTATTTAGGCTTTCGCGAAGCAACGCAAGGGATCGT
AATGAACATCCTGCGTCGCAAGATGCCTGCCGAGAAGATTAACGAAAATCTCGTTCAGCGCGGCATCATGATTTTCGCCA
TTTTGCTGGCCTGGAGCGCCATCGTACTGAACGCACCGGTGTTGAGCTTCACCTCTATCTGTAGCCCGATTTTCGGCATG
GTAGGGTGCCTGATCCCGGCGTGGCTGGTTTACAAAGTACCGGCATTGCACAAATACAAAGGGATGTCTCTGTACCTGAT
TATCGTCACTGGTTTGTTGCTTTGTGTTTCTCCGTTCCTGGCATTTTCTTGA

Upstream 100 bases:

>100_bases
CTTTATTCTAATAACTCGCCTGCAAAAACGTAGACCGCATATCGCCTTGATGCGGCTCGGAAAAAAATAATAAGCCCTAC
AAAATATTGAGCGAGAAATT

Downstream 100 bases:

>100_bases
TTTCCCTGAAATTTTAAGGTTTTTAATATGTTTGATTCGACTTTAAATCCGTTATGGCAGCGTTACATCCTCGCCGTTCA
GGAGGAAGTAAAACCGGCGC

Product: serine transporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMY
LFQRLFINTLAESPECKDYPSVISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGL
VLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSP
MVISYRSREKSIEVARHKALRAMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVS
VILNIFAVMTAFFGVYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTSICSPIFGM
VGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLAFS

Sequences:

>Translated_443_residues
MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMY
LFQRLFINTLAESPECKDYPSVISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGL
VLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSP
MVISYRSREKSIEVARHKALRAMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVS
VILNIFAVMTAFFGVYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTSICSPIFGM
VGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLAFS
>Mature_443_residues
MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMY
LFQRLFINTLAESPECKDYPSVISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGL
VLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSP
MVISYRSREKSIEVARHKALRAMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVS
VILNIFAVMTAFFGVYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTSICSPIFGM
VGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLAFS

Specific function: Unknown

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily

Homologues:

Organism=Escherichia coli, GI145693183, Length=443, Percent_Identity=100, Blast_Score=889, Evalue=0.0,
Organism=Escherichia coli, GI1789961, Length=408, Percent_Identity=44.6078431372549, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI1789160, Length=422, Percent_Identity=28.6729857819905, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1789504, Length=436, Percent_Identity=25.6880733944954, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789211, Length=412, Percent_Identity=22.5728155339806, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHAO_ECOLI (P42628)

Other databases:

- EMBL:   U18997
- EMBL:   U00096
- EMBL:   AP009048
- RefSeq:   AP_003658.1
- RefSeq:   YP_026203.3
- ProteinModelPortal:   P42628
- STRING:   P42628
- EnsemblBacteria:   EBESCT00000003100
- EnsemblBacteria:   EBESCT00000016515
- GeneID:   947628
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5519
- KEGG:   eco:b3110
- EchoBASE:   EB2609
- EcoGene:   EG12754
- eggNOG:   COG0814
- GeneTree:   EBGT00050000008986
- HOGENOM:   HBG297876
- OMA:   AMYLFQK
- ProtClustDB:   CLSK880592
- BioCyc:   EcoCyc:YHAO-MONOMER
- Genevestigator:   P42628
- InterPro:   IPR004694
- TIGRFAMs:   TIGR00814

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 48315; Mature: 48315

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1c5930ec)-; HASH(0x1c47eddc)-; HASH(0x1c5d6870)-; HASH(0x1b380830)-; HASH(0x1b5eac10)-; HASH(0x1c5e9eac)-; HASH(0x1c19e680)-; HASH(0x1c58cf74)-; HASH(0x1c15011c)-; HASH(0x1b9d9264)-; HASH(0x1c2afd7c)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQV
CCCCCCCCEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHH
GLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPSVISGYLGKNWGILLGALYF
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHH
VMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGLVLICILVAISSRGEKLLFKI
HHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEE
STGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVISYRSREKSIEVARHKALRAMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LAIAAQFISGDGAAWVKVVSVILNIFAVMTAFFGVYLGFREATQGIVMNILRRKMPAEKI
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
NENLVQRGIMIFAILLAWSAIVLNAPVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHC
GMSLYLIIVTGLLLCVSPFLAFS
CCHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQV
CCCCCCCCEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHH
GLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPSVISGYLGKNWGILLGALYF
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHH
VMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGLVLICILVAISSRGEKLLFKI
HHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEE
STGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVISYRSREKSIEVARHKALRAMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LAIAAQFISGDGAAWVKVVSVILNIFAVMTAFFGVYLGFREATQGIVMNILRRKMPAEKI
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
NENLVQRGIMIFAILLAWSAIVLNAPVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHC
GMSLYLIIVTGLLLCVSPFLAFS
CCHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503