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The map label for this gene is aquIMB

Identifier: 302334807

GI number: 302334807

Start: 1231349

End: 1231768

Strand: Direct

Name: aquIMB

Synonym: NA

Alternate gene names: 302334807

Gene position: 1231349-1231768 (Clockwise)

Preceding gene: 170077805

Following gene: 170077806

Centisome position: 40.94

GC content: 41.67

Gene sequence:

>420_bases
ATGGATATTAAAAACGTTCATATCAAAAATCACGAACAAACAGCTCATGCACCTTCCACTCTAGAAAAAATTCGTAAAGT
CAAACAAGGGGGTAAACTCTCAGAACAGACAAAGACATTTGGTTCAACCTACCGCAGGTTAGATCCGAACCAGCCATCTC
CTACAGTGACCCGTAGTGGTTATCGAGATTTTATTCATCCTTTTGAAGATCGAATGCTCACAGTTCGTGAACTGGCTTGT
TTGCAAACCTTTCCCCTTGATTGGGAGTTTACCGGAACTCGACTTGATTCTTATAGTAGTAAACGTAAAGTGACGATGAC
TCAGTTTGGACAAGTGGGTAATGCAGTACCGCCGTTACTTGCTGAAGCTGTTGCTAAAGCGGTTAGCGAACAGCTTCTGG
ATGTCATTGATGAAAAATAA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: Type II cytosine-5 DNA methyltransferase

Products: NA

Alternate protein names: M.AquI subunit beta; M.AquIB; Cytosine-specific methyltransferase AquI subunit beta

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:
NA

Sequences:

>Translated_139_residues
MDIKNVHIKNHEQTAHAPSTLEKIRKVKQGGKLSEQTKTFGSTYRRLDPNQPSPTVTRSGYRDFIHPFEDRMLTVRELAC
LQTFPLDWEFTGTRLDSYSSKRKVTMTQFGQVGNAVPPLLAEAVAKAVSEQLLDVIDEK
>Mature_139_residues
MDIKNVHIKNHEQTAHAPSTLEKIRKVKQGGKLSEQTKTFGSTYRRLDPNQPSPTVTRSGYRDFIHPFEDRMLTVRELAC
LQTFPLDWEFTGTRLDSYSSKRKVTMTQFGQVGNAVPPLLAEAVAKAVSEQLLDVIDEK

Specific function: This methylase recognizes the double-stranded sequence CYCGRG, causes specific methylation on C-1 on both strands, and protects the DNA from cleavage by the AquI endonuclease

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C5-methyltransferase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTAB_SYNP2 (P34883)

Other databases:

- EMBL:   M28051
- EMBL:   CP000951
- RefSeq:   YP_003828901.1
- ProteinModelPortal:   P34883
- REBASE:   3283
- GeneID:   9488071
- GenomeReviews:   CP000951_GR
- OMA:   RELACLQ
- InterPro:   IPR018117
- InterPro:   IPR001525
- PANTHER:   PTHR10629

Pfam domain/function: PF00145 DNA_methylase

EC number: =2.1.1.37

Molecular weight: Translated: 15760; Mature: 15760

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS00095 C5_MTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKNVHIKNHEQTAHAPSTLEKIRKVKQGGKLSEQTKTFGSTYRRLDPNQPSPTVTRSG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
YRDFIHPFEDRMLTVRELACLQTFPLDWEFTGTRLDSYSSKRKVTMTQFGQVGNAVPPLL
HHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHH
AEAVAKAVSEQLLDVIDEK
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDIKNVHIKNHEQTAHAPSTLEKIRKVKQGGKLSEQTKTFGSTYRRLDPNQPSPTVTRSG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
YRDFIHPFEDRMLTVRELACLQTFPLDWEFTGTRLDSYSSKRKVTMTQFGQVGNAVPPLL
HHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHH
AEAVAKAVSEQLLDVIDEK
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2104605