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The map label for this gene is phr [H]

Identifier: 170079382

GI number: 170079382

Start: 2918298

End: 2919731

Strand: Reverse

Name: phr [H]

Synonym: SYNPCC7002_A2796

Alternate gene names: 170079382

Gene position: 2919731-2918298 (Counterclockwise)

Preceding gene: 170079383

Following gene: 170079379

Centisome position: 97.06

GC content: 50.56

Gene sequence:

>1434_bases
ATGGCTGAACTGGTTTTACATTGGCATCGGCGAGATTTGCGGCTACAGGATAATGTTGCCTTGGCAGAAGCACGGCAACA
GTCGGCCAAGGTGGTCGGCATTTTCTGCCTCGATCCGGCCATTTTAGAAAAAGAAGATGTGGCTCCAGCGCGGGTGAAAT
ATCTGTTAGCGTGCCTGGCAGAATTGGCAGAAAATTACCAAAAAGCGGGCAGTCAACTACTGATTTTCCAGGGGAATCCC
TTAGAGGTCTTGCCCAAAGTTGCAGAATCTCTCAAAGTCCATACGGTCTACTGGAATCTGGACGTGGAACCCTATGCCCA
ACAGCGGGATCACCAGATGGCGATCGCCTTGCGTCAGGTAGGAGCCAAGATAGAAACCTTTTGGGATCAGCTCCTCCATG
CACCAGGAAAGGTCTTCACCCAATCTAAAAAGCCCTACAGCGTGTATTCGCCGTTCTGGAAAAACTGGTCGCAAAAGTCG
AAAGCCGCCCCCGTTACTGCCCTCAGAGATTGCCAAGGACTGAGTGATGCCGAACAGAAATTAGCGAAAGACCTAGGGGC
GATCGCCTTACCGACCTTGGCTGATCTGGGCTTCAGTTGGGACAAACCGTTTACTGTACCTGTGGGGGAAACTGCCAGCC
TGGGGCAATTAGATAGATTTACCGAGAATTTTATTGAGAAATACGATGGCGATCGCAACTTCCCGGCGACCGATGGCACC
TCCCGCCTTAGTGCCGCGTTGAAATTTGGGGCGATCGGCATTCGGACGGTTTGGCAAGCCACAGAAACTGCCCTAAACCA
CTGCCGCAGTAAAGAAGCAGAAGCTGGCGTCATCACCTGGCAGCAGGAATTAGCCTGGCGAGAATTTTATCAACACTGTC
TCTTTTTCTTTCCGGAACTTGCCCAGGGGCCATACCGGGAAGAGTTTAAAGACTTTCCTTGGGAAAATGACGAAGAAAAA
TTCCAGGCCTGGTGCGCTGGTCAAACGGGCTATCCGATTATTGATGCAGCGATGCGCCAACTTAATGAAACGGGCTGGAT
GCATAACCGCTGTCGGATGATTGTCGCCAGTTTTCTCACCAAGGATTTGATTATCGATTGGCGTTGGGGCGAAAAATATT
TTATGCAAACCCTGGTTGATGGTGATCTTGCGGCGAATAATGGTGGTTGGCAGTGGAGTGCTTCCAGCGGCATGGATCCT
AAACCCCTGCGAATTTTTAACCCTTATACCCAAGCGCAGAAATTTGACCCCGAAGCAGACTACATTCGCCACTGGCTACC
AGAGCTCAGTGGTTTGGATACCCAGGTTTTACTCACGGGCCAAATTCCCCGTTTACTCTGTCAGCAACACGATTACCCAG
AACCGATTGTGGAACACCGGGTACGCCAGCGGGAATTTAAGCGACTCTACAAATTAGTCAAAGACAAAGCCTAA

Upstream 100 bases:

>100_bases
AATAATAAAGAGATAAATGCCAGGAGTCGGGCTTTGCCTTGCTCCTTTTTTGTGGCTCGATTAGGATATAAGCCGCAGCG
AATGGGGCAATTTTTTAAGA

Downstream 100 bases:

>100_bases
ACAAAACGGGTGAGATTAACGCGATAGCGTTCTTTTTTGGTCATGTTGATCTCGCCAACTTCGACGCGGCCTTTGCCCCT
GAGGGAAATCAGATCACCCG

Product: deoxyribopyrimidine photolyase

Products: NA

Alternate protein names: DNA photolyase; Photoreactivating enzyme [H]

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MAELVLHWHRRDLRLQDNVALAEARQQSAKVVGIFCLDPAILEKEDVAPARVKYLLACLAELAENYQKAGSQLLIFQGNP
LEVLPKVAESLKVHTVYWNLDVEPYAQQRDHQMAIALRQVGAKIETFWDQLLHAPGKVFTQSKKPYSVYSPFWKNWSQKS
KAAPVTALRDCQGLSDAEQKLAKDLGAIALPTLADLGFSWDKPFTVPVGETASLGQLDRFTENFIEKYDGDRNFPATDGT
SRLSAALKFGAIGIRTVWQATETALNHCRSKEAEAGVITWQQELAWREFYQHCLFFFPELAQGPYREEFKDFPWENDEEK
FQAWCAGQTGYPIIDAAMRQLNETGWMHNRCRMIVASFLTKDLIIDWRWGEKYFMQTLVDGDLAANNGGWQWSASSGMDP
KPLRIFNPYTQAQKFDPEADYIRHWLPELSGLDTQVLLTGQIPRLLCQQHDYPEPIVEHRVRQREFKRLYKLVKDKA

Sequences:

>Translated_477_residues
MAELVLHWHRRDLRLQDNVALAEARQQSAKVVGIFCLDPAILEKEDVAPARVKYLLACLAELAENYQKAGSQLLIFQGNP
LEVLPKVAESLKVHTVYWNLDVEPYAQQRDHQMAIALRQVGAKIETFWDQLLHAPGKVFTQSKKPYSVYSPFWKNWSQKS
KAAPVTALRDCQGLSDAEQKLAKDLGAIALPTLADLGFSWDKPFTVPVGETASLGQLDRFTENFIEKYDGDRNFPATDGT
SRLSAALKFGAIGIRTVWQATETALNHCRSKEAEAGVITWQQELAWREFYQHCLFFFPELAQGPYREEFKDFPWENDEEK
FQAWCAGQTGYPIIDAAMRQLNETGWMHNRCRMIVASFLTKDLIIDWRWGEKYFMQTLVDGDLAANNGGWQWSASSGMDP
KPLRIFNPYTQAQKFDPEADYIRHWLPELSGLDTQVLLTGQIPRLLCQQHDYPEPIVEHRVRQREFKRLYKLVKDKA
>Mature_476_residues
AELVLHWHRRDLRLQDNVALAEARQQSAKVVGIFCLDPAILEKEDVAPARVKYLLACLAELAENYQKAGSQLLIFQGNPL
EVLPKVAESLKVHTVYWNLDVEPYAQQRDHQMAIALRQVGAKIETFWDQLLHAPGKVFTQSKKPYSVYSPFWKNWSQKSK
AAPVTALRDCQGLSDAEQKLAKDLGAIALPTLADLGFSWDKPFTVPVGETASLGQLDRFTENFIEKYDGDRNFPATDGTS
RLSAALKFGAIGIRTVWQATETALNHCRSKEAEAGVITWQQELAWREFYQHCLFFFPELAQGPYREEFKDFPWENDEEKF
QAWCAGQTGYPIIDAAMRQLNETGWMHNRCRMIVASFLTKDLIIDWRWGEKYFMQTLVDGDLAANNGGWQWSASSGMDPK
PLRIFNPYTQAQKFDPEADYIRHWLPELSGLDTQVLLTGQIPRLLCQQHDYPEPIVEHRVRQREFKRLYKLVKDKA

Specific function: Involved in repair of UV radiation-induced DNA damage. Exhibits specific, light-dependent repair activity for a cyclobutyl pyrimidine dimer by catalyzing the light-dependent monomerization (300-600 nm) of the dimers (in cis-syn configuration), which are f

COG id: COG0415

COG function: function code L; Deoxyribodipyrimidine photolyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DNA photolyase domain [H]

Homologues:

Organism=Homo sapiens, GI4758072, Length=495, Percent_Identity=27.0707070707071, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI188536100, Length=486, Percent_Identity=26.5432098765432, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI188536103, Length=438, Percent_Identity=25.5707762557078, Blast_Score=150, Evalue=2e-36,
Organism=Escherichia coli, GI1786926, Length=469, Percent_Identity=39.6588486140725, Blast_Score=298, Evalue=4e-82,
Organism=Saccharomyces cerevisiae, GI6324962, Length=501, Percent_Identity=29.940119760479, Blast_Score=224, Evalue=2e-59,
Organism=Drosophila melanogaster, GI17137248, Length=490, Percent_Identity=29.3877551020408, Blast_Score=201, Evalue=9e-52,
Organism=Drosophila melanogaster, GI24585455, Length=490, Percent_Identity=29.3877551020408, Blast_Score=201, Evalue=9e-52,
Organism=Drosophila melanogaster, GI24648152, Length=466, Percent_Identity=26.8240343347639, Blast_Score=143, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002081
- InterPro:   IPR018394
- InterPro:   IPR006050
- InterPro:   IPR019947
- InterPro:   IPR005101
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00875 DNA_photolyase; PF03441 FAD_binding_7 [H]

EC number: =4.1.99.3 [H]

Molecular weight: Translated: 54729; Mature: 54598

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00394 DNA_PHOTOLYASES_1_1 ; PS00691 DNA_PHOTOLYASES_1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELVLHWHRRDLRLQDNVALAEARQQSAKVVGIFCLDPAILEKEDVAPARVKYLLACLA
CCCCEEEHHHCCCCCCCCHHHHHHHHCCCCEEEEEECCCHHHCCCCCCHHHHHHHHHHHH
ELAENYQKAGSQLLIFQGNPLEVLPKVAESLKVHTVYWNLDVEPYAQQRDHQMAIALRQV
HHHHHHHHCCCEEEEECCCCHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHH
GAKIETFWDQLLHAPGKVFTQSKKPYSVYSPFWKNWSQKSKAAPVTALRDCQGLSDAEQK
HHHHHHHHHHHHCCCCHHHCCCCCCCCHHCHHHHCCCHHCCCCCHHHHHHHCCCCHHHHH
LAKDLGAIALPTLADLGFSWDKPFTVPVGETASLGQLDRFTENFIEKYDGDRNFPATDGT
HHHHHCCHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCH
SRLSAALKFGAIGIRTVWQATETALNHCRSKEAEAGVITWQQELAWREFYQHCLFFFPEL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
AQGPYREEFKDFPWENDEEKFQAWCAGQTGYPIIDAAMRQLNETGWMHNRCRMIVASFLT
HCCCCHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KDLIIDWRWGEKYFMQTLVDGDLAANNGGWQWSASSGMDPKPLRIFNPYTQAQKFDPEAD
HHHEEEEECCHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCEEEECCHHHHHCCCCHHH
YIRHWLPELSGLDTQVLLTGQIPRLLCQQHDYPEPIVEHRVRQREFKRLYKLVKDKA
HHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AELVLHWHRRDLRLQDNVALAEARQQSAKVVGIFCLDPAILEKEDVAPARVKYLLACLA
CCCEEEHHHCCCCCCCCHHHHHHHHCCCCEEEEEECCCHHHCCCCCCHHHHHHHHHHHH
ELAENYQKAGSQLLIFQGNPLEVLPKVAESLKVHTVYWNLDVEPYAQQRDHQMAIALRQV
HHHHHHHHCCCEEEEECCCCHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHH
GAKIETFWDQLLHAPGKVFTQSKKPYSVYSPFWKNWSQKSKAAPVTALRDCQGLSDAEQK
HHHHHHHHHHHHCCCCHHHCCCCCCCCHHCHHHHCCCHHCCCCCHHHHHHHCCCCHHHHH
LAKDLGAIALPTLADLGFSWDKPFTVPVGETASLGQLDRFTENFIEKYDGDRNFPATDGT
HHHHHCCHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCH
SRLSAALKFGAIGIRTVWQATETALNHCRSKEAEAGVITWQQELAWREFYQHCLFFFPEL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
AQGPYREEFKDFPWENDEEKFQAWCAGQTGYPIIDAAMRQLNETGWMHNRCRMIVASFLT
HCCCCHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KDLIIDWRWGEKYFMQTLVDGDLAANNGGWQWSASSGMDPKPLRIFNPYTQAQKFDPEAD
HHHEEEEECCHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCEEEECCHHHHHCCCCHHH
YIRHWLPELSGLDTQVLLTGQIPRLLCQQHDYPEPIVEHRVRQREFKRLYKLVKDKA
HHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11254140; 8905231; 10896222; 10871367 [H]