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The map label for this gene is rnc [H]

Identifier: 170079136

GI number: 170079136

Start: 2647428

End: 2648204

Strand: Direct

Name: rnc [H]

Synonym: SYNPCC7002_A2542

Alternate gene names: 170079136

Gene position: 2647428-2648204 (Clockwise)

Preceding gene: 170079133

Following gene: 170079137

Centisome position: 88.01

GC content: 52.64

Gene sequence:

>777_bases
ATGACAAGCTTGCCTCCCTTTCAGCGATCGCCTCTTCTGTTACAGGCGTTGACCCACCGCTCCTTTGCCAACGAACAACC
AGAGACAATCCAAGACAATGAGCGCCTGGAATTTTTAGGCGATGCGGTGCTCAAGTTCATCATGGGAAAGCTACTGTACG
AGCGTTATCCTGACTTTCAAGAAGGGGAACTGAGCCGACTGCGGGCCAGTTTAGAAAATAATCGCCACCAATTGGCTGAA
TTTGCCCAGGTGTTGGGTCTCGATCAGATCTTGCGCCTCGGCAAAGGGGCCGAAAAGGAAGGGGCCAGGCAAAACCCAGA
AATTTTAAGTAATACCTTTGAGGCGGTCGTCGGGGCTTACTTTTTAGATGCGGGGATCGAAGCGGCGATCGCCTTTGTCG
AAACCTTAGTCATTCCCGTGGCCGATCGCCTCGTGCAACAACCAAGCGATCCCCTCGCCCAAAATTTCAAAGGCCAATTG
CAAGAGTGGGCCCTAGCAAACCACGGTGAAATTCCGAAATACAAAACCCTAAATGAATCCGGGGCCGACCATGCAAAAAC
TTTTACGGTGGCGGTTTATCTCCAAGGACAGGAATGGGGCCGGGGTCAAGCGGCCTCGAAGAAGCAAGCCCAAAAAGCCG
CAGCCCAGGTTGCTTTACAAAAATTAACCCCTTCATCAGTGCCCACCGAGCCGTCTCCTAAACCACCTGCAACAGATGAT
CGTTTTGCCCTCCTCCAAGCCCTTGCCACCCAAATCACCCCGCGCCAATCCCCTTAA

Upstream 100 bases:

>100_bases
CTCCTGAATCACCGTTGCTTATGAGTTGCAGTGATTGGCTTTTAGATGGTTTGACGCTAGGTTTATTTACTCTCTGAACA
TTATAAAGTTTCGCTTAACC

Downstream 100 bases:

>100_bases
TTGGGCGAGAAAATGGCTGTGCTTGATCCCCGATGCAGGCTTGGTTTGGTGTCGCTGCGAAAAATTTCGATACAATATAG
TGTGATTTACTTTACAAAAC

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MTSLPPFQRSPLLLQALTHRSFANEQPETIQDNERLEFLGDAVLKFIMGKLLYERYPDFQEGELSRLRASLENNRHQLAE
FAQVLGLDQILRLGKGAEKEGARQNPEILSNTFEAVVGAYFLDAGIEAAIAFVETLVIPVADRLVQQPSDPLAQNFKGQL
QEWALANHGEIPKYKTLNESGADHAKTFTVAVYLQGQEWGRGQAASKKQAQKAAAQVALQKLTPSSVPTEPSPKPPATDD
RFALLQALATQITPRQSP

Sequences:

>Translated_258_residues
MTSLPPFQRSPLLLQALTHRSFANEQPETIQDNERLEFLGDAVLKFIMGKLLYERYPDFQEGELSRLRASLENNRHQLAE
FAQVLGLDQILRLGKGAEKEGARQNPEILSNTFEAVVGAYFLDAGIEAAIAFVETLVIPVADRLVQQPSDPLAQNFKGQL
QEWALANHGEIPKYKTLNESGADHAKTFTVAVYLQGQEWGRGQAASKKQAQKAAAQVALQKLTPSSVPTEPSPKPPATDD
RFALLQALATQITPRQSP
>Mature_257_residues
TSLPPFQRSPLLLQALTHRSFANEQPETIQDNERLEFLGDAVLKFIMGKLLYERYPDFQEGELSRLRASLENNRHQLAEF
AQVLGLDQILRLGKGAEKEGARQNPEILSNTFEAVVGAYFLDAGIEAAIAFVETLVIPVADRLVQQPSDPLAQNFKGQLQ
EWALANHGEIPKYKTLNESGADHAKTFTVAVYLQGQEWGRGQAASKKQAQKAAAQVALQKLTPSSVPTEPSPKPPATDDR
FALLQALATQITPRQSP

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Homo sapiens, GI155030234, Length=222, Percent_Identity=33.7837837837838, Blast_Score=114, Evalue=7e-26,
Organism=Homo sapiens, GI155030236, Length=222, Percent_Identity=33.7837837837838, Blast_Score=114, Evalue=8e-26,
Organism=Escherichia coli, GI1788920, Length=218, Percent_Identity=37.1559633027523, Blast_Score=115, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17506883, Length=230, Percent_Identity=29.5652173913043, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193202651, Length=230, Percent_Identity=29.5652173913043, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17137682, Length=222, Percent_Identity=31.5315315315315, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 28470; Mature: 28338

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS50137 DS_RBD ; PS00517 RNASE_3_1 ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLPPFQRSPLLLQALTHRSFANEQPETIQDNERLEFLGDAVLKFIMGKLLYERYPDFQ
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
EGELSRLRASLENNRHQLAEFAQVLGLDQILRLGKGAEKEGARQNPEILSNTFEAVVGAY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
FLDAGIEAAIAFVETLVIPVADRLVQQPSDPLAQNFKGQLQEWALANHGEIPKYKTLNES
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GADHAKTFTVAVYLQGQEWGRGQAASKKQAQKAAAQVALQKLTPSSVPTEPSPKPPATDD
CCCHHEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
RFALLQALATQITPRQSP
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TSLPPFQRSPLLLQALTHRSFANEQPETIQDNERLEFLGDAVLKFIMGKLLYERYPDFQ
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
EGELSRLRASLENNRHQLAEFAQVLGLDQILRLGKGAEKEGARQNPEILSNTFEAVVGAY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
FLDAGIEAAIAFVETLVIPVADRLVQQPSDPLAQNFKGQLQEWALANHGEIPKYKTLNES
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GADHAKTFTVAVYLQGQEWGRGQAASKKQAQKAAAQVALQKLTPSSVPTEPSPKPPATDD
CCCHHEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
RFALLQALATQITPRQSP
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA