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The map label for this gene is ndhH [H]

Identifier: 170079135

GI number: 170079135

Start: 2646057

End: 2647241

Strand: Reverse

Name: ndhH [H]

Synonym: SYNPCC7002_A2541

Alternate gene names: 170079135

Gene position: 2647241-2646057 (Counterclockwise)

Preceding gene: 170079139

Following gene: 170079134

Centisome position: 88.01

GC content: 50.72

Gene sequence:

>1185_bases
ATGACAAGAATTGAAACTCGTACCGAACCTATGGTGATTAACATGGGGCCTCACCACCCCTCCATGCACGGCGTATTACG
CTTGATCGTCACCCTTGACGGGGAAGACGTCGTTGATTGCGAACCCGTCATCGGCTATCTGCATCGGGGTATGGAAAAAA
TTGCCGAAAATCGCACCAATGTCATGTATGTCCCCTATGTGAGTCGTTGGGACTACGCCGCAGGGATGTTTAACGAAGCG
ATCACCGTTAATGCCCCCGAAAAACTCGCCGATATCGAAGTGCCGAAGCGCGCCCAATATATCCGCGTGATCATGCTGGA
GCTGAACCGCATTGCCAATCACCTCCTTTGGCTTGGCCCCTTCCTCGCGGATGTCGGTGCCCAGACACCTTTCTTCTACA
TCTTCCGGGAACGGGAAATGATCTATGACCTGTGGGAAGCCGCCACCGGGATGCGCCTAATCAACAACAACTATTTCCGC
ATTGGTGGTGTAGCTGTCGATCTTCCCTACGGTTGGAACGATAAATGTTTAGATTTTTGCGACTATTTCGATCCCAAAGT
TGATGAATACGAAAAACTAATCACCAATAACCCCATTTTCCGCCGCCGGGTAGAAGGGGTCGGCACGATCACCCGCGATG
AAGCGATCAACTGGAGTCTGTCAGGGCCAATGTTGCGGGCCTCTGGGGTGAAATGGGATCTCCGCAAAGTGGATCACTAC
GAGTGTTATGACGATTTTGACTGGGATGTACAGTGGGAAACTGCTGGGGACTGCTTTGCCCGCTATTTGGTACGAATTCG
GGAAATGCGCGAGTCAGTGAAAATTATTCGCCAAGCCCTGAAAGGAATGCCCGGTGGTGCCTACGAAAACCTCGAAGCCA
AGCGGATGTTAGAAGGGAAAAAATCCGAATGGAACGACTTCGATTACCAATACATCGCGAAAAAAGTTGCGCCGACGTTC
AAAATCCCCGATGGCGAACATTATGTCCGTCTCGAAAGTGGCAAAGGCGAAGTGGGAATTTTCATTCAGGGCAATAACAA
TGTGTTCCCCTGGCGCTGGAAAATCCGTTCGGCAGACTTCAATAACCTCCAAATTTTGCCCCACCTGCTGAAAGGCGTGA
AGGTGGCGGACATTATGGCGATTCTCGGTAGCATTGACGTGATTATGGGTTCCGTTGACCGTTAA

Upstream 100 bases:

>100_bases
CGGTGATTCAGGAGATTGGAAAAACGCAATGCACAAACAAACCATCTCACCCCATCACCAGATTTAATTTAAATAAGCAT
AACGGAAGACCTGCGGATCC

Downstream 100 bases:

>100_bases
TTGTTCTGAGTGAGAAATGTGAAAGAGGGCTATGGCGGCTCTCTTTTTTTTGTTTGCGGTATTTAATAGTTTTGAAAATT
TGGAGACTAGAAAAATTATG

Product: NAD(P)H-quinone oxidoreductase subunit H

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase subunit H; NADH-plastoquinone oxidoreductase subunit H; NDH-1 subunit H; NDH-H [H]

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MTRIETRTEPMVINMGPHHPSMHGVLRLIVTLDGEDVVDCEPVIGYLHRGMEKIAENRTNVMYVPYVSRWDYAAGMFNEA
ITVNAPEKLADIEVPKRAQYIRVIMLELNRIANHLLWLGPFLADVGAQTPFFYIFREREMIYDLWEAATGMRLINNNYFR
IGGVAVDLPYGWNDKCLDFCDYFDPKVDEYEKLITNNPIFRRRVEGVGTITRDEAINWSLSGPMLRASGVKWDLRKVDHY
ECYDDFDWDVQWETAGDCFARYLVRIREMRESVKIIRQALKGMPGGAYENLEAKRMLEGKKSEWNDFDYQYIAKKVAPTF
KIPDGEHYVRLESGKGEVGIFIQGNNNVFPWRWKIRSADFNNLQILPHLLKGVKVADIMAILGSIDVIMGSVDR

Sequences:

>Translated_394_residues
MTRIETRTEPMVINMGPHHPSMHGVLRLIVTLDGEDVVDCEPVIGYLHRGMEKIAENRTNVMYVPYVSRWDYAAGMFNEA
ITVNAPEKLADIEVPKRAQYIRVIMLELNRIANHLLWLGPFLADVGAQTPFFYIFREREMIYDLWEAATGMRLINNNYFR
IGGVAVDLPYGWNDKCLDFCDYFDPKVDEYEKLITNNPIFRRRVEGVGTITRDEAINWSLSGPMLRASGVKWDLRKVDHY
ECYDDFDWDVQWETAGDCFARYLVRIREMRESVKIIRQALKGMPGGAYENLEAKRMLEGKKSEWNDFDYQYIAKKVAPTF
KIPDGEHYVRLESGKGEVGIFIQGNNNVFPWRWKIRSADFNNLQILPHLLKGVKVADIMAILGSIDVIMGSVDR
>Mature_393_residues
TRIETRTEPMVINMGPHHPSMHGVLRLIVTLDGEDVVDCEPVIGYLHRGMEKIAENRTNVMYVPYVSRWDYAAGMFNEAI
TVNAPEKLADIEVPKRAQYIRVIMLELNRIANHLLWLGPFLADVGAQTPFFYIFREREMIYDLWEAATGMRLINNNYFRI
GGVAVDLPYGWNDKCLDFCDYFDPKVDEYEKLITNNPIFRRRVEGVGTITRDEAINWSLSGPMLRASGVKWDLRKVDHYE
CYDDFDWDVQWETAGDCFARYLVRIREMRESVKIIRQALKGMPGGAYENLEAKRMLEGKKSEWNDFDYQYIAKKVAPTFK
IPDGEHYVRLESGKGEVGIFIQGNNNVFPWRWKIRSADFNNLQILPHLLKGVKVADIMAILGSIDVIMGSVDR

Specific function: NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758786, Length=392, Percent_Identity=41.0714285714286, Blast_Score=298, Evalue=5e-81,
Organism=Homo sapiens, GI260898743, Length=386, Percent_Identity=40.4145077720207, Blast_Score=287, Evalue=1e-77,
Organism=Escherichia coli, GI145693162, Length=388, Percent_Identity=38.4020618556701, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1789076, Length=386, Percent_Identity=30.0518134715026, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1788832, Length=393, Percent_Identity=29.2620865139949, Blast_Score=133, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17568379, Length=392, Percent_Identity=40.0510204081633, Blast_Score=306, Evalue=2e-83,
Organism=Caenorhabditis elegans, GI17555284, Length=392, Percent_Identity=39.7959183673469, Blast_Score=305, Evalue=3e-83,
Organism=Drosophila melanogaster, GI221459469, Length=390, Percent_Identity=42.5641025641026, Blast_Score=326, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24638644, Length=397, Percent_Identity=40.3022670025189, Blast_Score=320, Evalue=1e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885 [H]

Pfam domain/function: PF00346 Complex1_49kDa [H]

EC number: 1.6.5.3

Molecular weight: Translated: 45609; Mature: 45478

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRIETRTEPMVINMGPHHPSMHGVLRLIVTLDGEDVVDCEPVIGYLHRGMEKIAENRTN
CCCCCCCCCCEEEEECCCCCHHHHEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCC
VMYVPYVSRWDYAAGMFNEAITVNAPEKLADIEVPKRAQYIRVIMLELNRIANHLLWLGP
EEEECCCCCCCHHHHHCCCCEEECCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FLADVGAQTPFFYIFREREMIYDLWEAATGMRLINNNYFRIGGVAVDLPYGWNDKCLDFC
HHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCEEECCCEEEECCEEEECCCCCCHHHHHHH
DYFDPKVDEYEKLITNNPIFRRRVEGVGTITRDEAINWSLSGPMLRASGVKWDLRKVDHY
HHCCCCHHHHHHHHCCCCHHHHHHHCCCCEECCCCEEEECCCCEEEECCCEEEHHCCCCC
ECYDDFDWDVQWETAGDCFARYLVRIREMRESVKIIRQALKGMPGGAYENLEAKRMLEGK
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCC
KSEWNDFDYQYIAKKVAPTFKIPDGEHYVRLESGKGEVGIFIQGNNNVFPWRWKIRSADF
CCCCCCCCHHHHHHHHCCCEECCCCCEEEEEECCCCCEEEEEECCCCEEEEEEEEECCCC
NNLQILPHLLKGVKVADIMAILGSIDVIMGSVDR
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TRIETRTEPMVINMGPHHPSMHGVLRLIVTLDGEDVVDCEPVIGYLHRGMEKIAENRTN
CCCCCCCCCEEEEECCCCCHHHHEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCC
VMYVPYVSRWDYAAGMFNEAITVNAPEKLADIEVPKRAQYIRVIMLELNRIANHLLWLGP
EEEECCCCCCCHHHHHCCCCEEECCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FLADVGAQTPFFYIFREREMIYDLWEAATGMRLINNNYFRIGGVAVDLPYGWNDKCLDFC
HHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCEEECCCEEEECCEEEECCCCCCHHHHHHH
DYFDPKVDEYEKLITNNPIFRRRVEGVGTITRDEAINWSLSGPMLRASGVKWDLRKVDHY
HHCCCCHHHHHHHHCCCCHHHHHHHCCCCEECCCCEEEECCCCEEEECCCEEEHHCCCCC
ECYDDFDWDVQWETAGDCFARYLVRIREMRESVKIIRQALKGMPGGAYENLEAKRMLEGK
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCC
KSEWNDFDYQYIAKKVAPTFKIPDGEHYVRLESGKGEVGIFIQGNNNVFPWRWKIRSADF
CCCCCCCCHHHHHHHHCCCEECCCCCEEEEEECCCCCEEEEEECCCCEEEEEEEEECCCC
NNLQILPHLLKGVKVADIMAILGSIDVIMGSVDR
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA